Component: Eriocaulon buergerianum 谷精草


Description of the Component

Component ID
TCMH699
Latin Name
Eriocaulon buergerianum
English Name
Pipewart
Chinese Pinyin Name
Gu Jing Cao
中文名
谷精草
TCM Properties
Mild,Sweet
TCM Meridians
Stomach,Liver
Therapeutic Class English
Heat clearence
Therapeutic Class Chinese
清热
Functions
expel wind and heat and clear the eye of corneal opacity
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3418 Die Da Wan Hua You 跌打万花油
TCMFx3838 Er Mao Guan Yan Yao 鹅毛管眼药
TCMF810 Fu Ming Tablet 复明片
TCMF3411 Fu Ming Tablets 复明片
TCMFx1959 Ganji Powder 疳积散
TCMFx1297 Ganji Powder 疳积散
TCMFx5694 Shang Ke Wan Hua You 伤科万花油
TCMF5198 Tui Zhang Yan Ointment 退障眼膏
TCMFx6596 Xiao Er Chang Wei Kang Granules 小儿肠胃康颗粒
TCMF6575 Xue Ya Ping Tablets 血压平片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT287 TAS2R31 Taste receptor type 2 member 31 GPCR P59538
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT752 CSNK2A1 Casein kinase II alpha Kinase P68400
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1099 Neuraminidase
TCMT1108 Integrase
TCMT1176 Streptococcus pneumoniae
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC4612
Formula: C22H22O11

Ingredient ID: TCMC4357
Formula: C16H12O8

Ingredient ID: TCMC4280
Formula: C16H26O2

Ingredient ID: TCMC3088
Formula: C15H30O2

Ingredient ID: TCMC3067
Formula: C28H58

Ingredient ID: TCMC3003
Formula: C18H36O

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC1956
Formula: C7H6O4

Ingredient ID: TCMC182
Formula: C9H8O4

Ingredient ID: TCMC1422
Formula: C17H14O7

Ingredient ID: TCMC1329
Formula: C16H12O6

Ingredient ID: TCMC1105
Formula: C15H10O5

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC182 C9H8O4 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC847 C9H8O4 Caffeic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC897 C16H18O9 Chlorogenic Acid 354.1 -2.1962 2.23 -0.447 7 6 164.75 11 2 25 1
TCMC1105 C15H10O5 Emodin 270.05 -1.2665 2.56 0.664 2 3 94.83 4 3 20 0
TCMC1329 C16H12O6 Hispidulin 300.06 -1.9363 2.56 1.123 1 3 96.22 6 3 22 0
TCMC1422 C17H14O7 Jaceosidine 330.07 -1.9881 2.56 0.679 1 3 105.45 8 3 24 0
TCMC1956 C7H6O4 Protocatechuic Acid 154.03 -1.1604 1.79 0.536 2 3 77.76 4 1 11 0
TCMC2222 C8H8O4 Vanillic Acid 168.04 -0.7519 1.9 0.626 2 2 66.76 5 1 12 0
TCMC3003 C18H36O Fitone,Hexahydrofarnesyl Acetone 268.2766158 1.0346 3.33 8.221 1 0 17.07 12 0 19 2
TCMC3067 C28H58 Octacosane 394.4538519 -7.3854 4.54 16.272 0 0 0 25 0 28 2
TCMC3088 C15H30O2 Pentadecanoic Acid 241.2167552 -4.2875 2.89 6.52 2 0 40.13 13 0 17 2
TCMC4280 C16H26O2 Methyl Farnesoate 250.1932801 3.9251 3 4.763 2 0 26.3 8 0 18 0
TCMC4357 C16H12O8 Patuletin 332.0532173 -2.486 2.34 0.632 2 5 127.45 2 3 24 0
TCMC4612 C22H22O11 Hispidulin 7-Glucoside,Homoplataginin 462.1162115 -3.3162 2.67 -0.426 6 6 166.14 5 4 33 1

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1. General Information of the Component  
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3. Putative Targets  
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5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)