Description of the Component
Component ID |
TCMH285 |
Latin Name |
Dioscorea nipponica |
English Name |
Nippon yam |
Chinese Pinyin Name |
Chuan Long Shu Yu |
中文名 |
穿龙薯蓣 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
GBVU067-13, GBVT4919-13 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMFx457 | Di Ao Xin Xue Kang Capsule | 地奥心血康胶囊 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
| TCMT140 | CA5B | Carbonic anhydrase VB | Lyase | Q9Y2D0 |
| TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT143 | CA3 | Carbonic anhydrase III | Lyase | P07451 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
| TCMT193 | RELA | Nuclear factor NF-kappa-B p65 subunit | Transcription factor | Q04206 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
| TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT318 | HKDC1 | Putative hexokinase HKDC1 | Transferase | Q2TB90 |
| TCMT320 | MMP3 | Matrix metalloproteinase 3 | Hydrolase | P08254 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT38 | DRD2 | Dopamine D2 receptor | GPCR | P14416 |
| TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
| TCMT609 | CTSL | Cathepsin L | Unclassified | P07711 |
| TCMT64 | PPARD | Peroxisome proliferator-activated receptor delta | Nuclear receptor | Q03181 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1136 | Neuraminidase |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1243 | Aspergillus flavus |
| TCMT1251 | Candida albicans |
| TCMT1384 | Fusarium tricinctum |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
Ingredient Structrues
Ingredient ID: TCMC2476
Formula: C12H10O2
Ingredient ID: TCMC2222
Formula: C8H8O4
Ingredient ID: TCMC2199
Formula: C8H11NO
Ingredient ID: TCMC2117
Formula: C22H26O8
Ingredient ID: TCMC1956
Formula: C7H6O4
Ingredient ID: TCMC1839
Formula: C7H6O3
Ingredient ID: TCMC1501
Formula: C15H12O4
Ingredient ID: TCMC1284
Formula: C10H13NO2
Ingredient ID: TCMC1073
Formula: C33H52O8
Ingredient ID: TCMC1072
Formula: C27H42O3
Ingredient ID: TCMC1063
Formula: C45H72O16
Ingredient ID: TCMC1015
Formula: C11H10N2O
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC1015 | C11H10N2O | Deoxyvasicinone | 186.08 | -0.8417 | 2.34 | 1.937 | 3 | 0 | 32.67 | 0 | 3 | 14 | 0 |
| TCMC1063 | C45H72O16 | Dioscin | 868.48 | -3.9636 | 4.65 | 2.836 | 16 | 8 | 235.68 | 21 | 9 | 61 | 2 |
| TCMC1072 | C27H42O3 | Disogenin | 414.31 | 0.2771 | 4.1 | 6.041 | 3 | 1 | 38.69 | 5 | 6 | 30 | 1 |
| TCMC1073 | C33H52O8 | Disogluside | 576.37 | -1.4698 | 4.21 | 4.933 | 8 | 4 | 117.84 | 11 | 7 | 41 | 0 |
| TCMC1284 | C10H13NO2 | Gnf-Pf-5230 | 179.09 | -0.489 | 2.23 | 1.798 | 2 | 2 | 52.82 | 6 | 1 | 13 | 0 |
| TCMC1501 | C15H12O4 | Liquirtigenin | 256.07 | -1.3541 | 2.67 | 1.86 | 1 | 2 | 66.76 | 3 | 3 | 19 | 0 |
| TCMC1839 | C7H6O3 | Paraben | 138.03 | -0.7001 | 1.9 | 1.07 | 2 | 2 | 57.53 | 3 | 1 | 10 | 0 |
| TCMC1956 | C7H6O4 | Protocatechuic Acid | 154.03 | -1.1604 | 1.79 | 0.536 | 2 | 3 | 77.76 | 4 | 1 | 11 | 0 |
| TCMC2117 | C22H26O8 | Syringaresinol | 418.16 | -2.1258 | 3 | 0.796 | 2 | 2 | 95.84 | 12 | 4 | 30 | 0 |
| TCMC2199 | C8H11NO | Tyramine | 137.08 | -0.943 | 2.12 | 1.104 | 1 | 2 | 46.25 | 4 | 1 | 10 | 0 |
| TCMC2222 | C8H8O4 | Vanillic Acid | 168.04 | -0.7519 | 1.9 | 0.626 | 2 | 2 | 66.76 | 5 | 1 | 12 | 0 |
| TCMC2476 | C12H10O2 | Chimaphilin | 186.07 | 0.9219 | 2.56 | 2.464 | 2 | 0 | 34.14 | 2 | 2 | 14 | 0 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
