Component: Paeonia obovata 芍药

Description of the Component

Component ID
Latin Name
Paeonia obovata
English Name
Red peony root
Chinese Pinyin Name
Shao Yao
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2850 Bao Yin Decoction 保阴煎
TCMF2747 Bupleurum and Cinnamon Twig Decoction 柴胡桂枝汤
TCMF2787 Cinnamon Twig and Persica Decoction 折冲饮
TCMF2763 Cinnamon Twig Decoction plus Astragalus 桂枝加黄芪汤
TCMF2762 Cinnamon Twig Decoction plus Magnolia and Apricot Seed 桂枝加厚朴杏仁汤
TCMF2766 Cinnamon Twig Decoction plus Peony 桂枝加芍药汤
TCMF2765 Cinnamon Twig Decoction Plus Peony and Rhubarb 桂枝加芍药大黄汤
TCMF2764 Cinnamon Twig, Licorice, Dragon Bone, and Oyster Shell Decoction 桂枝加龙骨牡蛎汤
TCMF2861 Da Yuan Decoction 达原饮
TCMF2894 Dang Gui Decoction 当归汤
TCMF2818 Dang Gui Jian Zhong Decoction 当归建中汤
TCMF2802 Dang Gui Si Ni Decoction 当归四逆汤
TCMF2896 Fu Ling Decoction 茯苓饮
TCMF2803 Fu Zi Decoction 附子汤
TCMF2901 Gui Zhi Jia Hou Pu Xing Ren Decoction 桂枝加厚朴杏仁汤
TCMF2902 Gui Zhi Jia Huang Qi Decoction 桂枝加黄芪汤
TCMF2903 Gui Zhi Jia Long Gu Mu Li Decoction 桂枝加龙骨牡蛎汤
TCMF2904 Gui Zhi Jia Shao Yao Da Huang Decoction 桂枝加芍药大黄汤
TCMF2905 Gui Zhi Jia Shao Yao Decoction 桂枝加芍药汤
TCMF2804 Gui Zhi Shao Yao Zhi Mu Decoction 桂枝芍药知母汤
TCMFx2851 Hua Gan Decoction 化肝煎
TCMF2805 Huang Qi Gui Zhi Wu Wu Decoction 黄芪桂枝五物汤
TCMF2822 Kai Xin Powder 开心散
TCMF2778 Peony, Licorice, and Prepared Aconite Decoction 芍药甘草附子汤
TCMF2756 Poria Decoction 茯苓饮
TCMF2773 Pus Discharging Powder and Decoction 排脓散及汤
TCMF2752 Tang kuei Decoction 当归汤
TCMF2828 Wen Jing Decoction 温经汤
TCMF2821 Xiao Xu Ming Decoction 小续命汤
TCMF6485 Yu Dai Pills 愈带丸
TCMFx2797 Zhen Wu Decoction 真武汤

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT212 SRC Tyrosine-protein kinase SRC Kinase P12931
TCMT221 ABCB11 Bile salt export pump Transporter O95342
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT230 HSD17B3 Estradiol 17-beta-dehydrogenase 3 Oxidoreductase P37058
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT283 PTPRS Receptor-type tyrosine-protein phosphatase S Hydrolase Q13332
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT354 AURKA Serine/threonine-protein kinase Aurora-A Kinase O14965
TCMT369 IGF1R Insulin-like growth factor I receptor Kinase P08069
TCMT370 KDR Vascular endothelial growth factor receptor 2 Kinase P35968
TCMT374 AURKB Serine/threonine-protein kinase Aurora-B Kinase Q96GD4
TCMT377 INSR Insulin receptor Kinase P06213
TCMT384 GRK6 G protein-coupled receptor kinase 6 Kinase P43250
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT418 EPHB4 Ephrin type-B receptor 4 Kinase P54760
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT436 NUAK1 NUAK family SNF1-like kinase 1 Kinase O60285
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT441 PTK2 Focal adhesion kinase 1 Kinase Q05397
TCMT457 FLT4 Vascular endothelial growth factor receptor 3 Kinase P35916
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT484 PLK1 Serine/threonine-protein kinase PLK1 Kinase P53350
TCMT502 TEK Tyrosine-protein kinase TIE-2 Kinase Q02763
TCMT536 PDGFRB Platelet-derived growth factor receptor beta Kinase P09619
TCMT560 F10 Coagulation factor X Unclassified P00742
TCMT588 DAO D-amino-acid oxidase Oxidoreductase P14920
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT601 F2 Thrombin Unclassified P00734
TCMT61 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 Unclassified Q07820
TCMT620 HSPA8 Heat shock cognate 71 kDa protein Unclassified P11142
TCMT626 BRAF Serine/threonine-protein kinase B-raf Kinase P15056
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT654 GRM5 Metabotropic glutamate receptor 5 GPCR P41594
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT704 ERBB2 Receptor protein-tyrosine kinase erbB-2 Kinase P04626
TCMT721 HSPA1A Heat shock 70 kDa protein 1 Unclassified P0DMV8
TCMT739 GPR35 G-protein coupled receptor 35 GPCR Q9HC97
TCMT751 DYRK1A Dual-specificity tyrosine-phosphorylation regulated kinase 1A Kinase Q13627
TCMT752 CSNK2A1 Casein kinase II alpha Kinase P68400
TCMT753 SMAD3 Mothers against decapentaplegic homolog 3 Unclassified P84022
TCMT754 GSTP1 Glutathione S-transferase Pi Transferase P09211
TCMT755 PLK4 Serine/threonine-protein kinase PLK4 Kinase O00444
TCMT756 MAP3K8 Mitogen-activated protein kinase kinase kinase 8 Kinase P41279
TCMT757 CARM1 Histone-arginine methyltransferase CARM1 Transferase Q86X55
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1104 Sortase
TCMT1108 Integrase
TCMT1109 Reverse transcriptase
TCMT1178 Actinomyces viscosus
TCMT1189 Pseudomonas fluorescens
TCMT1190 Plasmodium falciparum (isolate FcB1 / Columbia)
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1249 Dengue virus 2
TCMT1251 Candida albicans
TCMT1294 Human parainfluenza virus 3
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1412 Salmonella typhimurium
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC913
Formula: C15H14O6

Ingredient ID: TCMC90
Formula: C15H14O7

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC770
Formula: C7H6O2

Ingredient ID: TCMC76
Formula: C15H12O7

Ingredient ID: TCMC756
Formula: C21H18O11

Ingredient ID: TCMC755
Formula: C15H10O5

Ingredient ID: TCMC3
Formula: C15H14O6

Ingredient ID: TCMC2667
Formula: C30H50O

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC2107
Formula: C29H48O

Ingredient ID: TCMC2037
Formula: C7H6O3

Ingredient ID: TCMC1977
Formula: C6H6O3

Ingredient ID: TCMC1948
Formula: C10H12O5

Ingredient ID: TCMC1851
Formula: C41H32O26

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1826
Formula: C9H10O3

Ingredient ID: TCMC1495
Formula: C18H32O2

Ingredient ID: TCMC1343
Formula: C6H6O2

Ingredient ID: TCMC1203
Formula: C8H8O5

Ingredient ID: TCMC1202
Formula: C7H6O5

Ingredient ID: TCMC1192
Formula: C30H50O

Ingredient ID: TCMC1158
Formula: C41H30O26

Ingredient ID: TCMC1102
Formula: C14H6O8


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC3 C15H14O6 (-)-Catechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC76 C15H12O7 (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One 304.06 -2.9269 2.34 0.028 2 5 127.45 6 3 22 0
TCMC90 C15H14O7 (2S,3S)-2-(3,4,5-Trihydroxy-Phenyl)-Chroman-3,5,7-Triol 306.07 -2.9543 2.34 -0.128 1 6 130.61 7 3 22 1
TCMC755 C15H10O5 Baicalein 270.05 -1.8845 2.56 3.058 1 3 86.99 4 3 20 0
TCMC756 C21H18O11 Baicalin 446.08 -3.5292 2.56 1.678 7 6 183.21 10 4 32 1
TCMC770 C7H6O2 Benzoic Acid 122.04 -0.2398 2.01 2.666 2 1 37.3 2 1 9 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC913 C15H14O6 Cianidanol 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC995 C35H60O6 Daucosterol 576.44 -0.4469 4.65 10.487 6 4 99.38 19 5 41 1
TCMC1102 C14H6O8 Ellagic Acid 302.01 -2.0234 2.12 -0.046 2 4 133.52 4 4 22 0
TCMC1158 C41H30O26 Eugeniin 938.1 -7.5719 3.11 -0.135 11 15 444.18 24 7 67 2
TCMC1192 C30H50O Friedeline 426.39 3.2175 4.65 12.613 1 0 17.07 8 5 31 1
TCMC1202 C7H6O5 Gallic Acid 170.02 -1.6207 1.68 0.002 2 4 97.99 5 1 12 0
TCMC1203 C8H8O5 Gallic Acid Methyl Ester 184.04 -1.3697 1.79 0.323 2 3 86.99 6 1 13 0
TCMC1343 C6H6O2 Hydroquinone 110.04 -0.9206 1.9 0.87 0 2 40.46 2 1 8 0
TCMC1495 C18H32O2 Linoleic Acid 280.24 -0.9485 3.22 7.865 2 1 37.3 16 0 20 2
TCMC1826 C9H10O3 Paeonol 166.06 -0.766 2.12 1.32 1 1 46.53 5 1 12 0
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1851 C41H32O26 Pentagalloyl Glucose 940.12 -7.5719 3.11 0.697 11 15 444.18 31 6 67 3
TCMC1948 C10H12O5 Propyl Gallate 212.07 -1.6971 2.01 1.104 2 3 86.99 8 1 15 0
TCMC1977 C6H6O3 Pyrogallol 126.03 -1.3809 1.79 0.765 0 3 60.69 3 1 9 0
TCMC2037 C7H6O3 Salicylic Acid 138.03 -0.7001 1.9 2.264 2 2 57.53 3 1 10 0
TCMC2107 C29H48O Stigmasterol 412.37 1.2566 4.54 11.071 1 1 20.23 12 4 30 1
TCMC2222 C8H8O4 Vanillic Acid 168.04 -0.7519 1.9 0.626 2 2 66.76 5 1 12 0
TCMC2667 C30H50O Beta-Amyrin 426.39 3.0116 4.65 11.546 1 1 20.23 9 5 31 1

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1. General Information of the Component  
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3. Putative Targets  
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5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)