Component: Gerbera piloselloides 毛大丁草


Description of the Component

Component ID
TCMH1452
Latin Name
Gerbera piloselloides
English Name
Pilose gerbera
Chinese Pinyin Name
Mao Da Ding Cao
中文名
毛大丁草
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
ITSAK2411-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx6892 Xing Pi Yang Er Granules 醒脾养儿颗粒

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT102 ACP1 Low molecular weight phosphotyrosine protein phosphatase Hydrolase P24666
TCMT103 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) Hydrolase P10586
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT214 MGLL Monoglyceride lipase Unclassified Q99685
TCMT22 ALPI Intestinal alkaline phosphatase Hydrolase P09923
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT233 PTPN11 Protein-tyrosine phosphatase 2C Hydrolase Q06124
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT47 BCL2 Apoptosis regulator Bcl-2 Ion channel P10415
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT566 NOS2 Nitric oxide synthase, inducible Oxidoreductase P35228
TCMT598 TOP1 DNA topoisomerase I Isomerase P11387
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT60 FASN Fatty acid synthase Unclassified P49327
TCMT601 F2 Thrombin Unclassified P00734
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT640 CTSD Cathepsin D Unclassified P07339
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1093 Enoyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1107 Protease
TCMT1175 Human immunodeficiency virus
TCMT1178 Actinomyces viscosus
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1189 Pseudomonas fluorescens
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1231 Human herpesvirus 1 strain KOS
TCMT1248 Hepatitis C virus
TCMT1255 Human immunodeficiency virus 1
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1390 Human herpesvirus 2 strain G
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC913
Formula: C15H14O6

Ingredient ID: TCMC804
Formula: C30H48O3

Ingredient ID: TCMC803
Formula: C30H50O2

Ingredient ID: TCMC2694
Formula: C20H24O6

Ingredient ID: TCMC2667
Formula: C30H50O

Ingredient ID: TCMC2518
Formula: C30H48O2

Ingredient ID: TCMC2404
Formula: C30H50

Ingredient ID: TCMC2233
Formula: C21H20O10

Ingredient ID: TCMC2218
Formula: C30H50O2

Ingredient ID: TCMC2216
Formula: C30H48O3

Ingredient ID: TCMC2120
Formula: C17H24O9

Ingredient ID: TCMC1786
Formula: C30H48O3

Ingredient ID: TCMC1418
Formula: C21H20O10

Ingredient ID: TCMC13
Formula: C15H14O6

Ingredient ID: TCMC1192
Formula: C30H50O

Ingredient ID: TCMC1127
Formula: C30H50O2

Ingredient ID: TCMC1117
Formula: C15H14O7

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC13 C15H14O6 (-)-Epicatechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC803 C30H50O2 Betulin 442.38 2.1406 4.54 9.714 2 2 40.46 10 5 32 1
TCMC804 C30H48O3 Betulinic Acid 456.36 2.3495 4.43 9.407 3 2 57.53 10 5 33 1
TCMC913 C15H14O6 Cianidanol 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC1117 C15H14O7 Epigallocatechin 306.07 -2.9543 2.34 -0.128 1 6 130.61 7 3 22 1
TCMC1127 C30H50O2 Erythrodiol 442.38 1.9209 4.54 9.359 2 2 40.46 10 5 32 1
TCMC1192 C30H50O Friedeline 426.39 3.2175 4.65 12.613 1 0 17.07 8 5 31 1
TCMC1418 C21H20O10 Isovitexin 432.11 -4.1202 2.67 -0.508 6 7 177.14 10 4 31 1
TCMC1786 C30H48O3 Oleanolic_Acid 456.36 2.1298 4.43 9.052 3 2 57.53 10 5 33 1
TCMC2120 C17H24O9 Syringin 372.14 -2.2917 2.34 -0.417 6 5 138.07 14 2 26 0
TCMC2216 C30H48O3 Ursolic Acid 456.36 1.4838 4.43 8.954 3 2 57.53 10 5 33 1
TCMC2218 C30H50O2 Uvaol 442.38 1.2749 4.54 9.261 2 2 40.46 10 5 32 1
TCMC2233 C21H20O10 Vitexin 432.11 -4.1202 2.67 -0.508 6 7 177.14 10 4 31 1
TCMC2404 C30H50 Squalene 410.39 8.5524 4.76 11.482 0 0 0 23 0 30 2
TCMC2518 C30H48O2 Betulone 440.37 2.7103 4.54 9.107 2 1 37.3 9 5 32 1
TCMC2667 C30H50O Beta-Amyrin 426.39 3.0116 4.65 11.546 1 1 20.23 9 5 31 1
TCMC2694 C20H24O6 Isolariciresinol 360.16 -2.2141 3 1.061 2 4 99.38 11 3 26 0

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