Component: Ligusticum sinense 藁本


Description of the Component

Component ID
TCMH670
Latin Name
Ligusticum sinense
English Name
Chinese ligusticum
Chinese Pinyin Name
Gao Ben
中文名
藁本
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
Shaanxi Province, Liaoning Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAP3226-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx2918 An Kun Zan Yu Pills 安坤赞育丸
TCMF159 Bi Yuan Tong Qiao Granules 鼻渊通窍颗粒
TCMFx3251 Chi Tong Ning 齿痛宁
TCMF1920 Decoction of Notopterygium for Rheumatism 羌活胜湿汤
TCMF7233 Diao Yi Fang Lie Ointment 貂胰防裂膏
TCMF3756 Fu Bao Jin Pills 妇宝金丸
TCMFx3870 Fu Ke Jin Dan 妇科金丹
TCMF4819 Jin Bu Huan Ointment 金不换膏
TCMF4667 Kun Ling Pills 坤灵丸
TCMFx4483 Liu Jing Tou Tong Tablets 六经头痛片
TCMFx224 Nü Jin Capsule 女金胶囊
TCMFx163 Nv Jin Pills 女金丸
TCMFx4397 Nv Jin Syrup 女金糖浆
TCMFx4385 Nv Jin Tablets 女金片
TCMFx4413 Nv Sheng Jin Dan 女胜金丹
TCMF7382 Qiang Huo Sheng Shi Decoction 羌活胜湿汤
TCMF2839 Qiang Huo Sheng Shi Decoction 羌活胜湿汤
TCMF5177 Qiang Li Tian Ma Du Zhong Capsules 强力天麻杜仲胶囊
TCMF5443 Qing Nao Fu Shen Oral Liquid 清脑复神液
TCMFx5475 Ren Shen Nv Jin Pills 人参女金丸
TCMFx5669 Shang Ke Fu Yao 伤科敷药
TCMF5215 Tai Chan Jin Pills 胎产金丸
TCMF257 Tian Ju Nao An Capsule 天菊脑安胶囊
TCMFx5473 Tian Ma Zhui Feng Ointment 天麻追风膏
TCMF5385 Wan Ying Bao Zhen Ointment 万应宝珍膏
TCMF6584 Xiao Er Bi Yan Tablets 小儿鼻炎片
TCMF2825 Xin Yi Powder 辛夷散
TCMF7347 Xin Yi Powder 辛夷散
TCMF6242 Xiong Ju Shang Qing Granules 芎菊上清颗粒
TCMF127 Xiong Ju Shang Qing Pills 芎菊上清丸
TCMF6257 Xiong Ju Shang Qing Pills 芎菊上清丸
TCMF6249 Xiong Ju Shang Qing Tablets 芎菊上清片
TCMF128 Xiong Ju Shang Qing Tablets 芎菊上清片
TCMFx6472 Yi Kun Pills 益坤丸
TCMF1142 Zhen Nao Ning Capsule 镇脑宁胶囊
TCMF6607 Zhui Feng Ointment 追风膏
TCMF6686 Zhui Feng Zhuang Gu Ointment 追风壮骨膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT117 OPRK1 Kappa opioid receptor GPCR P41145
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT127 PARP1 Poly [ADP-ribose] polymerase-1 Transferase P09874
TCMT128 TNKS2 Tankyrase-2 Transferase Q9H2K2
TCMT129 TNKS Tankyrase-1 Transferase O95271
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT186 MAOB Monoamine oxidase B Oxidoreductase P27338
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT193 RELA Nuclear factor NF-kappa-B p65 subunit Transcription factor Q04206
TCMT195 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Kinase Q02750
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT203 G6PD Glucose-6-phosphate 1-dehydrogenase Oxidoreductase P11413
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT208 MAOA Monoamine oxidase A Oxidoreductase P21397
TCMT212 SRC Tyrosine-protein kinase SRC Kinase P12931
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT217 CYP2C8 Cytochrome P450 2C8 Oxidoreductase P10632
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT220 CYP2J2 Cytochrome P450 2J2 Oxidoreductase P51589
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT241 CHRNA7 Neuronal acetylcholine receptor protein alpha-7 subunit Ion channel P36544
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT331 PLG Plasminogen Unclassified P00747
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT36 HTR1A Serotonin 1a (5-HT1a) receptor GPCR P08908
TCMT369 IGF1R Insulin-like growth factor I receptor Kinase P08069
TCMT370 KDR Vascular endothelial growth factor receptor 2 Kinase P35968
TCMT374 AURKB Serine/threonine-protein kinase Aurora-B Kinase Q96GD4
TCMT377 INSR Insulin receptor Kinase P06213
TCMT388 AXL Tyrosine-protein kinase receptor UFO Kinase P30530
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT402 ALK ALK tyrosine kinase receptor Kinase Q9UM73
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT422 CAMK2B CaM kinase II beta Kinase Q13554
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT436 NUAK1 NUAK family SNF1-like kinase 1 Kinase O60285
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT441 PTK2 Focal adhesion kinase 1 Kinase Q05397
TCMT445 NEK2 Serine/threonine-protein kinase NEK2 Kinase P51955
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT460 MAPKAPK2 MAP kinase-activated protein kinase 2 Kinase P49137
TCMT462 NEK6 Serine/threonine-protein kinase NEK6 Kinase Q9HC98
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT484 PLK1 Serine/threonine-protein kinase PLK1 Kinase P53350
TCMT507 MAPK14 MAP kinase p38 alpha Kinase Q16539
TCMT508 SYK Tyrosine-protein kinase SYK Kinase P43405
TCMT555 HDAC6 Histone deacetylase 6 Hydrolase Q9UBN7
TCMT556 HDAC2 Histone deacetylase 2 Hydrolase Q92769
TCMT557 HDAC1 Histone deacetylase 1 Hydrolase Q13547
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT571 ADORA2B Adenosine A2b receptor GPCR P29275
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT601 F2 Thrombin Unclassified P00734
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT629 ABCC1 Multidrug resistance-associated protein 1 Transporter P33527
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT690 HDAC3 Histone deacetylase 3 Hydrolase O15379
TCMT691 HDAC8 Histone deacetylase 8 Hydrolase Q9BY41
TCMT734 MMP12 Matrix metalloproteinase 12 Hydrolase P39900
TCMT739 GPR35 G-protein coupled receptor 35 GPCR Q9HC97
TCMT740 PIK3CG PI3-kinase p110-gamma subunit Transferase P48736
TCMT747 ABCG2 ATP-binding cassette sub-family G member 2 Transporter Q9UNQ0
TCMT752 CSNK2A1 Casein kinase II alpha Kinase P68400
TCMT784 AVPR2 Vasopressin V2 receptor GPCR P30518
TCMT785 CXCR1 Interleukin-8 receptor A GPCR P25024
TCMT786 CCR4 C-C chemokine receptor type 4 GPCR P51679
TCMT791 PKN1 Protein kinase N1 Kinase Q16512
TCMT793 PYGL Liver glycogen phosphorylase Transferase P06737
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1092 Fatty acid synthase
TCMT1093 Enoyl-acyl-carrier protein reductase
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1104 Sortase
TCMT1108 Integrase
TCMT1109 Reverse transcriptase
TCMT1121 Sialidase
TCMT1136 Neuraminidase
TCMT1178 Actinomyces viscosus
TCMT1208 Escherichia coli K12
TCMT1209 Staphylococcus haemolyticus
TCMT1210 Streptococcus sobrinus
TCMT1211 Fusobacterium nucleatum
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1245 Phytophthora cactorum
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1282 Colletotrichum orbiculare
TCMT1286 Bacillus cereus
TCMT1294 Human parainfluenza virus 3
TCMT1321 Staphylococcus hominis
TCMT1343 Staphylococcus simulans
TCMT1344 Staphylococcus sciuri
TCMT1346 Helicobacter pylori
TCMT1349 Helicobacter pylori SS1
TCMT1361 Neisseria meningitidis
TCMT1370 Prevotella melaninogenica
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1393 Vibrio sp.
TCMT1408 Colletotrichum gloeosporioides
TCMT1412 Salmonella typhimurium
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1443 Leishmania amazonensis
TCMT1447 Respiratory syncytial virus
TCMT1448 Enterobacter aerogenes
TCMT1449 Influenza A virus
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC924
Formula: C10H20O

Ingredient ID: TCMC906
Formula: C9H6O2

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC837
Formula: C4H8O2

Ingredient ID: TCMC834
Formula: C4H8O

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC774
Formula: C7H8O

Ingredient ID: TCMC748
Formula: C30H48O4

Ingredient ID: TCMC737
Formula: C21H20O11

Ingredient ID: TCMC711
Formula: C21H20O10

Ingredient ID: TCMC710
Formula: C15H10O5

Ingredient ID: TCMC671
Formula: C10H16

Ingredient ID: TCMC6643
Formula: C15H20O4

Ingredient ID: TCMC60
Formula: C10H16O

Ingredient ID: TCMC5725
Formula: C12H16O4

Ingredient ID: TCMC5596
Formula: C12H14O2

Ingredient ID: TCMC5091
Formula: C11H12O3

Ingredient ID: TCMC4990
Formula: C10H18O

Ingredient ID: TCMC4859
Formula: C12H16O4

Ingredient ID: TCMC4858
Formula: C12H16O3

Ingredient ID: TCMC4735
Formula: C11H10O4

Ingredient ID: TCMC4478
Formula: C21H20O8

Ingredient ID: TCMC4250
Formula: C12H18O2

Ingredient ID: TCMC372
Formula: C8H10O

Ingredient ID: TCMC3583
Formula: C12H18O2

Ingredient ID: TCMC304
Formula: C10H18O

Ingredient ID: TCMC284
Formula: C10H16

Ingredient ID: TCMC2822
Formula: C15H24

Ingredient ID: TCMC276
Formula: C8H7NO

Ingredient ID: TCMC2688
Formula: C12H16O3

Ingredient ID: TCMC2650
Formula: C12H14O4

Ingredient ID: TCMC2550
Formula: C15H24

Ingredient ID: TCMC255
Formula: C15H12O4

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2539
Formula: C10H16

Ingredient ID: TCMC2484
Formula: C10H18O

Ingredient ID: TCMC2381
Formula: C8H10O

Ingredient ID: TCMC2354
Formula: C10H14O

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC2248
Formula: C12H12O2

Ingredient ID: TCMC2223
Formula: C8H8O3

Ingredient ID: TCMC2222
Formula: C8H8O4