Component: Speranskia tuberculata 透骨草

Description of the Component

Component ID
Latin Name
Speranskia tuberculata
English Name
Tuberculate speranskia
Chinese Pinyin Name
Tou Gu Cao
TCM Properties
TCM Meridians
Therapeutic Class English
For dispelling wind-dampness
Therapeutic Class Chinese
For dispelling wind-dampness and dispersing coldness
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx2937 A Wei She Xiang Hua Ji Ointment 阿魏麝香化积膏
TCMF2009 Bitter Seng Itching Stoper Decoction 苦参止痒汤
TCMFx3626 Fu Fang Jing Jie Xun Xi Ji 复方荆芥熏洗剂
TCMF2279 Haemorrhoid Smoking and Cleansing Recipe 痔疮熏洗方
TCMFx4437 Huo Xue Zhen Tong Ointment 活血镇痛膏
TCMF4284 Jin Gu Ning Cha Ji 筋骨宁搽剂
TCMFx4430 Jing Zhi Gou Pi Ointment 精制狗皮膏
TCMFx5174 Qu Feng Shi Zhi Tong Powder 祛风湿止痛散
TCMFx5703 Shang Ke Zhuang Gu Ointment 伤科壮骨膏
TCMFx5319 Shen Jin Huo Luo Pills 伸筋活络丸
TCMF5446 Shu Jin Zhi Tong Ding 舒筋止痛酊
TCMFx1146 Shu Tong An Plastics 疏痛安涂膜剂
TCMFx5613 Shu Tong An Tu Mo Ji 疏痛安涂膜剂
TCMFx5293 Wai Yong Wu Di Ointment 外用无敌膏
TCMF5740 Xi Shang Le Ding 息伤乐酊
TCMFx6106 Xin Xing Gou Pi Ointment 新型狗皮膏
TCMFx6031 Yang Xue Rong Jin Pills 养血荣筋丸
TCMFx837 Yang Xue Rong Jin Pills 养血荣筋丸
TCMFx6310 Zheng Gu Ointment 正骨膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT191 STAT3 Signal transducer and activator of transcription 3 Transcription factor P40763
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1438 Plasmodium falciparum
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC1427
Formula: C10H6O3


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC1427 C10H6O3 Juglone 174.03 -0.7335 2.23 0.575 2 1 54.37 1 2 13 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)