Component: Adiantum capillus-veneris 铁线草


Description of the Component

Component ID
 TCMH2114
Latin Name
 Adiantum capillus-veneris
English Name
 NA
Chinese Pinyin Name
 Tie Xian Cao
中文名
 铁线草
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
 NA
Geo-authentic habitats (道地产区)
 NA
Reference
 Chinese Classical Prescriptions
Barcode ID
 VASCB748-15
Barcode Source
 BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx6251 Xiao Shi Tablets 消石片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT186 MAOB Monoamine oxidase B Oxidoreductase P27338
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT191 STAT3 Signal transducer and activator of transcription 3 Transcription factor P40763
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT208 MAOA Monoamine oxidase A Oxidoreductase P21397
TCMT209 HSD11B2 11-beta-hydroxysteroid dehydrogenase 2 Oxidoreductase P80365
TCMT218 CYP2B6 Cytochrome P450 2B6 Oxidoreductase P20813
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT22 ALPI Intestinal alkaline phosphatase Hydrolase P09923
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT230 HSD17B3 Estradiol 17-beta-dehydrogenase 3 Oxidoreductase P37058
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT279 VDR Vitamin D receptor Nuclear receptor P11473
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT301 PTGES Prostaglandin E synthase Isomerase O14684
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT559 ADRB2 Beta-2 adrenergic receptor GPCR P07550
TCMT564 PRMT1 Protein-arginine N-methyltransferase 1 Transferase Q99873
TCMT565 EP300 Histone acetyltransferase p300 Transferase Q09472
TCMT566 NOS2 Nitric oxide synthase, inducible Oxidoreductase P35228
TCMT567 DNMT1 DNA (cytosine-5)-methyltransferase 1 Transferase P26358
TCMT568 DNMT3B DNA (cytosine-5)-methyltransferase 3B Transferase Q9UBC3
TCMT570 ANPEP Aminopeptidase N Unclassified P15144
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1085 Neuraminidase
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1104 Sortase
TCMT1108 Integrase
TCMT1112 Quinolone resistance protein norA
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1215 Pseudomonas aeruginosa PAO1
TCMT1218 Staphylococcus aureus
TCMT1221 Human herpesvirus 4
TCMT1224 Proteus mirabilis
TCMT1226 Klebsiella pneumoniae
TCMT1246 Escherichia coli
TCMT1249 Dengue virus 2
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1313 Human immunodeficiency virus 2
TCMT1314 Streptococcus viridans
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC962
Formula: C21H20O6

Ingredient ID: TCMC857
Formula: C10H16O

Ingredient ID: TCMC819
Formula: C19H16O4

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC638
Formula: C15H22O3

Ingredient ID: TCMC503
Formula: C10H10O3

Ingredient ID: TCMC43
Formula: C21H20O6

Ingredient ID: TCMC41
Formula: C15H24O3

Ingredient ID: TCMC1962
Formula: C18H14O8

Ingredient ID: TCMC1938
Formula: C15H22O2

Ingredient ID: TCMC1776
Formula: C8H16O2

Ingredient ID: TCMC170
Formula: C10H14O

Ingredient ID: TCMC1421
Formula: C15H24O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC41 C15H24O3 (1Alpha,4Alpha,5Beta,10Beta)-4,5-Dihydroxy-7(11)-Guaien-8-One 252.17 0.7404 2.78 1.151 3 2 57.53 6 2 18 0
TCMC43 C21H20O6 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 368.13 -0.7948 3.11 2.847 2 2 93.06 12 2 27 0
TCMC170 C10H14O (S)(+)Carvone 150.1 1.5954 2.45 1.756 1 0 17.07 3 1 11 0
TCMC503 C10H10O3 4-Methoxycinnamic Acid 178.06 0.0695 2.23 2.405 2 1 46.53 5 1 13 0
TCMC638 C15H22O3 Aerugidiol 250.16 1.3797 2.78 0.513 3 2 57.53 6 2 18 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC819 C19H16O4 Bisdemethoxycurcumin 308.1 -0.6912 3.11 4.157 2 2 74.6 8 2 23 0
TCMC857 C10H16O Camphor 152.12 0.9693 2.45 2.127 1 0 17.07 3 2 11 0
TCMC962 C21H20O6 Curcumin 368.13 -0.6611 3.11 2.955 2 3 96.22 12 2 27 0
TCMC1421 C15H24O3 Isozedoarondiol 252.17 0.7404 2.78 1.151 3 2 57.53 6 2 18 0
TCMC1776 C8H16O2 Octanoic Acid 144.12 -1.5937 2.12 3.018 2 1 37.3 8 0 10 0
TCMC1938 C15H22O2 Procurcumenol 234.16 2.0906 2.89 1.671 2 1 37.3 5 2 17 0
TCMC1962 C18H14O8 Psoromic Acid 358.07 0.0945 2.56 2.677 4 2 119.36 8 3 26 0

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