Component: Centipeda minima 鹅不食草


Description of the Component

Component ID
TCMH536
Latin Name
Centipeda minima
English Name
Small centipeda
Chinese Pinyin Name
E Bu Shi Cao
中文名
鹅不食草
TCM Properties
TCM Meridians
Therapeutic Class English
For relieving exterior syndrome
Therapeutic Class Chinese
解表
Functions
relieve nasal obstruction and cough
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAJ4316-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx7119 Bi Kang Tablets 鼻康片
TCMF3596 Bi Shu Shi Tablets 鼻舒适片
TCMFx3603 Bi Tong Ning Di Ji 鼻通宁滴剂
TCMF3609 Bi Tong Pills 鼻通丸
TCMF1168 Bi Yan Kang Tablet 鼻炎康片
TCMFx3672 Bi Yan Syrup 鼻炎糖浆
TCMF3803 Cang E Bi Yan Tablets 苍鹅鼻炎片
TCMF3994 Dan Xiang Bi Yan Tablets 胆香鼻炎片
TCMFx3341 Die Da Bang Yao Wine 跌打榜药酒
TCMF3169 Fang Zhi Bi Yan Tablets 防芷鼻炎片
TCMF6996 Fu Fang Jue Ming Tablets 复方决明片
TCMFx4399 Granules Sha Capsules 克痢痧胶囊
TCMFx4407 Granules Sha Wei Pills 克痢痧微丸
TCMF4566 Hou Tong Tablets 喉痛片
TCMFx597 Ke Li Sha Capsule 克痢痧胶囊
TCMFx4186 Liang Cai Xin Die Da Pills 梁财信跌打丸
TCMFx4862 Luo Fu Shan Bai Cao You 罗浮山百草油
TCMFx129 Qin Zhi Bi Yan Syrup 芩芷鼻炎糖浆
TCMFx5344 Re Ke Ping Zhu She Oral Liquid 热可平注射液
TCMFx162 Tong Guan Powder 通关散
TCMF566 Xin Yi Bi Yan Pills 辛夷鼻炎丸
TCMF6060 Xin Yi Bi Yan Pills 辛夷鼻炎丸
TCMFx328 Zhong Hua Die Da Pills 中华跌打丸
TCMFx6238 Zhong Hua Die Da Pills 中华跌打丸
TCMFx6231 Zhong Hua Die Da Wine 中华跌打酒

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT103 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) Hydrolase P10586
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT193 RELA Nuclear factor NF-kappa-B p65 subunit Transcription factor Q04206
TCMT195 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Kinase Q02750
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT212 SRC Tyrosine-protein kinase SRC Kinase P12931
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT217 CYP2C8 Cytochrome P450 2C8 Oxidoreductase P10632
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT220 CYP2J2 Cytochrome P450 2J2 Oxidoreductase P51589
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT233 PTPN11 Protein-tyrosine phosphatase 2C Hydrolase Q06124
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT329 NQO2 Quinone reductase 2 Oxidoreductase P16083
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT331 PLG Plasminogen Unclassified P00747
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT36 HTR1A Serotonin 1a (5-HT1a) receptor GPCR P08908
TCMT369 IGF1R Insulin-like growth factor I receptor Kinase P08069
TCMT370 KDR Vascular endothelial growth factor receptor 2 Kinase P35968
TCMT374 AURKB Serine/threonine-protein kinase Aurora-B Kinase Q96GD4
TCMT388 AXL Tyrosine-protein kinase receptor UFO Kinase P30530
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT402 ALK ALK tyrosine kinase receptor Kinase Q9UM73
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT422 CAMK2B CaM kinase II beta Kinase Q13554
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT436 NUAK1 NUAK family SNF1-like kinase 1 Kinase O60285
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT441 PTK2 Focal adhesion kinase 1 Kinase Q05397
TCMT445 NEK2 Serine/threonine-protein kinase NEK2 Kinase P51955
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT460 MAPKAPK2 MAP kinase-activated protein kinase 2 Kinase P49137
TCMT462 NEK6 Serine/threonine-protein kinase NEK6 Kinase Q9HC98
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT484 PLK1 Serine/threonine-protein kinase PLK1 Kinase P53350
TCMT507 MAPK14 MAP kinase p38 alpha Kinase Q16539
TCMT508 SYK Tyrosine-protein kinase SYK Kinase P43405
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT559 ADRB2 Beta-2 adrenergic receptor GPCR P07550
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT601 F2 Thrombin Unclassified P00734
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT629 ABCC1 Multidrug resistance-associated protein 1 Transporter P33527
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT734 MMP12 Matrix metalloproteinase 12 Hydrolase P39900
TCMT737 APOBEC3G DNA dC->dU-editing enzyme APOBEC-3G Unclassified Q9HC16
TCMT739 GPR35 G-protein coupled receptor 35 GPCR Q9HC97
TCMT740 PIK3CG PI3-kinase p110-gamma subunit Transferase P48736
TCMT747 ABCG2 ATP-binding cassette sub-family G member 2 Transporter Q9UNQ0
TCMT784 AVPR2 Vasopressin V2 receptor GPCR P30518
TCMT785 CXCR1 Interleukin-8 receptor A GPCR P25024
TCMT786 CCR4 C-C chemokine receptor type 4 GPCR P51679
TCMT791 PKN1 Protein kinase N1 Kinase Q16512
TCMT793 PYGL Liver glycogen phosphorylase Transferase P06737
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1092 Fatty acid synthase
TCMT1093 Enoyl-acyl-carrier protein reductase
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1108 Integrase
TCMT1109 Reverse transcriptase
TCMT1121 Sialidase
TCMT1136 Neuraminidase
TCMT1170 Enterobacter cloacae
TCMT1184 Mycobacterium fortuitum
TCMT1198 Serratia marcescens
TCMT1208 Escherichia coli K12
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1232 Pseudomonas aeruginosa
TCMT1243 Aspergillus flavus
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1261 Pseudomonas savastanoi pv. savastanoi
TCMT1286 Bacillus cereus
TCMT1289 Shigella dysenteriae
TCMT1294 Human parainfluenza virus 3
TCMT1346 Helicobacter pylori
TCMT1349 Helicobacter pylori SS1
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1394 Mycobacterium aurum
TCMT1412 Salmonella typhimurium
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1443 Leishmania amazonensis
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC6084
Formula: C46H80O2

Ingredient ID: TCMC5433
Formula: C30H50O2

Ingredient ID: TCMC5328
Formula: C12H8O6

Ingredient ID: TCMC5294
Formula: C27H28N2O4

Ingredient ID: TCMC462
Formula: C16H12O7

Ingredient ID: TCMC4525
Formula: C17H14O7

Ingredient ID: TCMC4324
Formula: C29H48O

Ingredient ID: TCMC383
Formula: C13H10N2O

Ingredient ID: TCMC318
Formula: C14H12N2O2

Ingredient ID: TCMC282
Formula: C13H10N2O

Ingredient ID: TCMC2705
Formula: C17H28O2

Ingredient ID: TCMC2653
Formula: C20H26O5

Ingredient ID: TCMC2594
Formula: C6H13NO2

Ingredient ID: TCMC2493
Formula: C20H40O

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC2188
Formula: C17H14O7

Ingredient ID: TCMC2182
Formula: C20H40O

Ingredient ID: TCMC2107
Formula: C29H48O

Ingredient ID: TCMC1982
Formula: C15H10O7

Ingredient ID: TCMC1980
Formula: C10H6Cl2N2O2

Ingredient ID: TCMC1956
Formula: C7H6O4

Ingredient ID: TCMC1955
Formula: C7H6O3

Ingredient ID: TCMC1899
Formula: C20H22O6

Ingredient ID: TCMC1868
Formula: C13H8N2O2

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC182
Formula: C9H8O4

Ingredient ID: TCMC1512
Formula: C9H11NO2

Ingredient ID: TCMC1329
Formula: C16H12O6

Ingredient ID: TCMC1173
Formula: C10H10O4

Ingredient ID: TCMC1075
Formula: C6H13NO2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC182 C9H8O4 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC282 C13H10N2O 1-Methoxyphenazine 210.08 -0.0518 2.56 3.164 2 0 35.01 2 3 16 0
TCMC318 C14H12N2O2 2,3-Dimethoxyphenazine 240.09 -0.1036 2.56 2.72 2 0 44.24 4 3 18 0
TCMC383 C13H10N2O 2-Methoxyphenazine 210.08 -0.0518 2.56 3.164 2 0 35.01 2 3 16 0
TCMC462 C16H12O7 3-O-Methylquercetin 316.06 -2.7367 2.45 1.273 2 4 116.45 7 3 23 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC847 C9H8O4 Caffeic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC897 C16H18O9 Chlorogenic Acid 354.1 -2.1962 2.23 -0.447 7 6 164.75 11 2 25 1
TCMC1075 C6H13NO2 D-Leucine 131.09 -0.3183 1.79 -1.389 3 2 63.32 7 0 9 0
TCMC1173 C10H10O4 Ferulic Acid 194.06 -0.3908 2.12 1.231 2 2 66.76 6 1 14 0
TCMC1329 C16H12O6 Hispidulin 300.06 -1.9363 2.56 1.123 1 3 96.22 6 3 22 0
TCMC1512 C9H11NO2 L-Phenylalanine 165.08 -1.0844 2.12 0.441 3 2 63.32 5 1 12 0
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1868 C13H8N2O2 Phenazine-1-Carboxylic Acid 224.06 -0.2398 2.45 2.845 4 1 63.08 2 3 17 0
TCMC1899 C20H22O6 Pinoresinol 358.14 -2.0222 3 1.684 2 2 77.38 8 4 26 0
TCMC1955 C7H6O3 Protocatechualdehyde 138.03 -1.113 1.9 0.95 1 2 57.53 3 1 10 0
TCMC1956 C7H6O4 Protocatechuic Acid 154.03 -1.1604 1.79 0.536 2 3 77.76 4 1 11 0
TCMC1980 C10H6Cl2N2O2 Pyrrolnitrin 255.98 1.7283 1.9 2.865 1 1 58.93 5 2 16 0
TCMC1982 C15H10O7 Quercetin 302.04 -2.8012 2.34 1.381 2 5 127.45 6 3 22 0
TCMC2107 C29H48O Stigmasterol 412.37 1.2566 4.54 11.071 1 1 20.23 12 4 30 1
TCMC2182 C20H40O Trans-Phytol 296.31 1.7816 3.55 8.949 1 1 20.23 19 0 21 2
TCMC2188 C17H14O7 Tricin 330.07 -1.9881 2.56 0.679 1 3 105.45 8 3 24 0
TCMC2222 C8H8O4 Vanillic Acid 168.04 -0.7519 1.9 0.626 2 2 66.76 5 1 12 0
TCMC2493 C20H40O 3,7,11,15-Tetramethylhexadec-2-En-1-Ol 296.31 1.7816 3.55 8.949 1 1 20.23 19 0 21 2
TCMC2594 C6H13NO2 Leucine 131.09 -0.3183 1.79 -1.389 3 2 63.32 7 0 9 0
TCMC2653 C20H26O5 Brevilin A 346.18 1.687 3.11 2.47 5 0 69.67 8 3 25 0
TCMC2705 C17H28O2 Resorstatin 264.21 -2.7092 3.11 6.426 0 2 40.46 13 1 19 1
TCMC4324 C29H48O Stigmasterol 412.3705162 1.2566 4.54 11.071 1 1 20.23 5 4 30 1
TCMC4525 C17H14O7 3,3'-Dimethylquercetin 330.0739528 -1.9612 2.56 1.058 2 3 96.22 3 3 24 0
TCMC5294 C27H28N2O4 Aurantiamide Acetate 444.2049074 -1.4219 3.77 9.175 6 2 84.5 13 3 33 2
TCMC5328 C12H8O6 Brevifolin 248.032088 -1.7454 2.12 0.22 3 3 94.83 0 3 18 0
TCMC5433 C30H50O2 Arnidiol 442.3810808 1.9907 4.54 9.289 2 2 40.46 0 5 32 1
TCMC6084 C46H80O2 Taraxasteryl Palmitate 664.6158318 -0.7249 6.3 20.186 2 0 26.3 16 5 48 2

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)