Component ID |
TCMH1024 |
Latin Name |
Tribulus terrestris |
English Name |
Puncturevine caltrop fruit |
Chinese Pinyin Name |
Ji Li |
中文名 |
蒺藜 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
For calming liver and containing wind |
Therapeutic Class Chinese |
平肝息风 |
Functions |
subdue hyperactivity of the liver, promote blood circulation, dispel wind, clear the eye of opacity, and arrest itching |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
Henan Province |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
ITSAJ4258-14 |
Barcode Source |
BOLDSYSTEMS |
Prescription ID | Prescription English Name | Prescription Chinese Name |
---|---|---|
TCMFx2951 | An Shen Pills | 安肾丸 |
TCMF477 | Bai Dian Feng Capsule | 白癜风胶囊 |
TCMF2988 | Bai Dian Feng Capsules | 白癜风胶囊 |
TCMF2995 | Bai Dian Feng Pills | 白癜风丸 |
TCMF3066 | Bai Shi Pills | 白蚀丸 |
TCMF475 | Bai Shi Pills | 白蚀丸 |
TCMFx3114 | Ban Feng He Yao Wine | 半枫荷药酒 |
TCMFx817 | Bao Ji Oral Liquid | 保济口服液 |
TCMF3350 | Bao Ji Oral Liquid | 保济口服液 |
TCMFx818 | Bao Ji Pills | 保济丸 |
TCMF3358 | Bao Ji Pills | 保济丸 |
TCMF3596 | Bi Shu Shi Tablets | 鼻舒适片 |
TCMFx7035 | Chuan Bai Zhi Yang Xi Ji | 川百止痒洗剂 |
TCMF3700 | Da Hu Zhuang Yuan Pills | 打虎壮元丸 |
TCMFx3838 | Er Mao Guan Yan Yao | 鹅毛管眼药 |
TCMF3169 | Fang Zhi Bi Yan Tablets | 防芷鼻炎片 |
TCMF3952 | Fu Fang Shi Hu Tablets | 复方石斛片 |
TCMF810 | Fu Ming Tablet | 复明片 |
TCMF3411 | Fu Ming Tablets | 复明片 |
TCMFx3937 | Gao Xue Ya Su Jiang Pills | 高血压速降丸 |
TCMF3515 | Gu Tong Pills | 骨痛丸 |
TCMF4085 | Huang Lian Yang Gan Tablets | 黄连羊肝片 |
TCMF4819 | Jin Bu Huan Ointment | 金不换膏 |
TCMFx199 | Jiu Wei Gan Tai Capsule | 九味肝泰胶囊 |
TCMF4804 | Kai Guang Fu Ming Pills | 开光复明丸 |
TCMF251 | Kai Guang Fu Ming Pills | 开光复明丸 |
TCMF4496 | Ming Mu Di Huang Pills | 明目地黄丸 |
TCMF4504 | Ming Mu Ji Li Pills | 明目蒺藜丸 |
TCMF4523 | Ming Mu Shang Qing Pills | 明目上清丸 |
TCMF636 | Ming Mu Shang Qing Tablet | 明目上清片 |
TCMF4514 | Ming Mu Shang Qing Tablets | 明目上清片 |
TCMF4852 | Niao Du Ling Guan Chang Oral Liquid | 尿毒灵灌肠液 |
TCMF6949 | Pi Min Xiao Capsules | 皮敏消胶囊 |
TCMF4999 | Qiang Xin Pills | 强心丸 |
TCMF5822 | Qing Xin Ming Mu Shang Qing Pills | 清心明目上清丸 |
TCMFx3551 | Shen Rong Gu Ben Huan Shao Pills | 参茸固本还少丸 |
TCMF5108 | Shi Hu Ming Mu Pills | 石斛明目丸 |
TCMF260 | Tian Ma Shou Wu Tablet | 天麻首乌片 |
TCMF5439 | Tian Ma Shou Wu Tablets | 天麻首乌片 |
TCMFx5739 | Tiao Gu Tablets | 跳骨片 |
TCMF6680 | Xie Gan An Shen Pills | 泻肝安神丸 |
TCMF680 | Xie Gan An Shen Pills | 泻肝安神丸 |
TCMFx6850 | Xin Nao Shu Tong Capsules | 心脑舒通胶囊 |
TCMF6598 | Xun Ma Zhen Pills | 荨麻疹丸 |
TCMFx7050 | Ye Lu Zhi Ke Recipe | 椰露止咳合剂 |
TCMFx1067 | Zhi Chuang Tablet | 痔疮片 |
TCMFx6132 | Zhi Chuang Tablets | 痔疮片 |
TCMF6686 | Zhui Feng Zhuang Gu Ointment | 追风壮骨膏 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
TCMT140 | CA5B | Carbonic anhydrase VB | Lyase | Q9Y2D0 |
TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
TCMT143 | CA3 | Carbonic anhydrase III | Lyase | P07451 |
TCMT151 | PRKCA | Protein kinase C alpha | Kinase | P17252 |
TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
TCMT161 | HCAR2 | Hydroxycarboxylic acid receptor 2 | GPCR | Q8TDS4 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
TCMT186 | MAOB | Monoamine oxidase B | Oxidoreductase | P27338 |
TCMT195 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | Kinase | Q02750 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT208 | MAOA | Monoamine oxidase A | Oxidoreductase | P21397 |
TCMT226 | PDPK1 | 3-phosphoinositide dependent protein kinase-1 | Kinase | O15530 |
TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
TCMT265 | GSK3B | Glycogen synthase kinase-3 beta | Kinase | P49841 |
TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
TCMT355 | CSNK1D | Casein kinase I delta | Kinase | P48730 |
TCMT374 | AURKB | Serine/threonine-protein kinase Aurora-B | Kinase | Q96GD4 |
TCMT407 | MYLK | Myosin light chain kinase, smooth muscle | Kinase | Q15746 |
TCMT417 | DYRK2 | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | Kinase | Q92630 |
TCMT42 | KMT2A | Histone-lysine N-methyltransferase MLL | Transferase | Q03164 |
TCMT445 | NEK2 | Serine/threonine-protein kinase NEK2 | Kinase | P51955 |
TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
TCMT458 | HASPIN | Serine/threonine-protein kinase haspin | Kinase | Q8TF76 |
TCMT460 | MAPKAPK2 | MAP kinase-activated protein kinase 2 | Kinase | P49137 |
TCMT462 | NEK6 | Serine/threonine-protein kinase NEK6 | Kinase | Q9HC98 |
TCMT466 | MAPK9 | c-Jun N-terminal kinase 2 | Kinase | P45984 |
TCMT473 | PIM3 | Serine/threonine-protein kinase PIM3 | Kinase | Q86V86 |
TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
TCMT484 | PLK1 | Serine/threonine-protein kinase PLK1 | Kinase | P53350 |
TCMT507 | MAPK14 | MAP kinase p38 alpha | Kinase | Q16539 |
TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
TCMT751 | DYRK1A | Dual-specificity tyrosine-phosphorylation regulated kinase 1A | Kinase | Q13627 |
TCMT763 | DYRK3 | Dual-specificity tyrosine-phosphorylation regulated kinase 3 | Kinase | O43781 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
TCMT814 | CLK1 | Dual specificty protein kinase CLK1 | Kinase | P49759 |
TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
TCMT829 | NISCH | Nischarin | Unclassified | Q9Y2I1 |
TCMT831 | DYRK4 | Dual specificity tyrosine-phosphorylation-regulated kinase 4 | Kinase | Q9NR20 |
TCMT832 | DYRK1B | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Kinase | Q9Y463 |
TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Target ID | Target Name |
---|---|
TCMT1218 | Staphylococcus aureus |
TCMT1223 | Staphylococcus epidermidis |
TCMT1246 | Escherichia coli |
TCMT1251 | Candida albicans |
TCMT1408 | Colletotrichum gloeosporioides |
TCMT1438 | Plasmodium falciparum |
TCMT1442 | Leishmania donovani |
TCMT1444 | Fusarium oxysporum |
TCMT1454 | Bacillus subtilis |
TCMT1463 | Mycobacterium tuberculosis |
Ingredient ID: TCMC5882
Formula: C27H44O4
Ingredient ID: TCMC3853
Formula: C27H42O4
Ingredient ID: TCMC3850
Formula: C27H44O4
Ingredient ID: TCMC2524
Formula: C34H28Br4N4O8
Ingredient ID: TCMC2512
Formula: C12H8S3
Ingredient ID: TCMC2500
Formula: C24H28N2O6
Ingredient ID: TCMC1767
Formula: C18H19NO4
Ingredient ID: TCMC1310
Formula: C12H10N2O
Ingredient ID: TCMC1309
Formula: C13H12N2O
Ingredient ID: TCMC1308
Formula: C12H10N2
Ingredient ID: TCMC1173
Formula: C10H10O4
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC1173 | C10H10O4 | Ferulic Acid | 194.06 | -0.3908 | 2.12 | 1.231 | 2 | 2 | 66.76 | 6 | 1 | 14 | 0 |
TCMC1308 | C12H10N2 | Harman | 182.08 | 0.0191 | 2.56 | 2.968 | 2 | 1 | 28.68 | 1 | 3 | 14 | 0 |
TCMC1309 | C13H12N2O | Harmine | 212.09 | -0.0327 | 2.56 | 2.313 | 2 | 1 | 37.91 | 3 | 3 | 16 | 0 |
TCMC1310 | C12H10N2O | Harmol | 198.08 | -0.8687 | 2.45 | 2.112 | 3 | 2 | 44.89 | 1 | 3 | 15 | 0 |
TCMC1767 | C18H19NO4 | N-Trans-Feruloyl Tyramine | 313.13 | -0.6499 | 2.89 | 3.109 | 2 | 3 | 82.28 | 10 | 2 | 23 | 0 |
TCMC2500 | C24H28N2O6 | Terrestribisamide | 440.19 | -1.4664 | 3.22 | 3.384 | 4 | 4 | 124.1 | 17 | 2 | 32 | 1 |
TCMC2512 | C12H8S3 | Alpha-Terthienyl | 247.98 | 1.7718 | 2.45 | 4.693 | 0 | 0 | 84.72 | 2 | 3 | 15 | 0 |
TCMC2524 | C34H28Br4N4O8 | Bastadin 13 | 935.86 | 1.875 | 3.44 | 8.378 | 4 | 6 | 189.28 | 10 | 4 | 50 | 2 |
TCMC3850 | C27H44O4 | Gitogenin | 432.3239599 | 0.1181 | 3.99 | 6.494 | 4 | 2 | 58.92 | 0 | 6 | 31 | 1 |
TCMC3853 | C27H42O4 | Ruscogenin | 430.3083098 | -0.296 | 3.99 | 4.378 | 4 | 2 | 58.92 | 0 | 6 | 31 | 0 |
TCMC5882 | C27H44O4 | Chlorogenin | 432.3239599 | -0.4255 | 3.99 | 5.432 | 4 | 2 | 58.92 | 0 | 6 | 31 | 1 |