Description of the Component
Component ID |
TCMH1024 |
Latin Name |
Tribulus terrestris |
English Name |
Puncturevine caltrop fruit |
Chinese Pinyin Name |
Ji Li |
中文名 |
蒺藜 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
For calming liver and containing wind |
Therapeutic Class Chinese |
平肝息风 |
Functions |
subdue hyperactivity of the liver, promote blood circulation, dispel wind, clear the eye of opacity, and arrest itching |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
Henan Province |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
ITSAJ4258-14 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF251 | Kai Guang Fu Ming Pills | 开光复明丸 |
| TCMF260 | Tian Ma Shou Wu Tablet | 天麻首乌片 |
| TCMF2988 | Bai Dian Feng Capsules | 白癜风胶囊 |
| TCMF2995 | Bai Dian Feng Pills | 白癜风丸 |
| TCMF3066 | Bai Shi Pills | 白蚀丸 |
| TCMF3169 | Fang Zhi Bi Yan Tablets | 防芷鼻炎片 |
| TCMF3350 | Bao Ji Oral Liquid | 保济口服液 |
| TCMF3358 | Bao Ji Pills | 保济丸 |
| TCMF3411 | Fu Ming Tablets | 复明片 |
| TCMF3515 | Gu Tong Pills | 骨痛丸 |
Showing 1 to 10 of 48 entries
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
| TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
Showing 1 to 10 of 59 entries
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1218 | Staphylococcus aureus |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1408 | Colletotrichum gloeosporioides |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
| TCMT1444 | Fusarium oxysporum |
| TCMT1454 | Bacillus subtilis |
| TCMT1463 | Mycobacterium tuberculosis |
Showing 1 to 10 of 10 entries
Ingredient Structrues
Ingredient ID: TCMC5882
Formula: C27H44O4
Ingredient ID: TCMC5882
| Common Name | Chlorogenin |
| IUPAC Name | (1R,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S,18S,19S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16,19-diol |
| Canonical SMILES | C[C@@H]1CC[C@@]2(OC1)O[C@@H]1[C@H]([C@@H]2C)[C@@]2([C@@H](C1)[C@@H]1C[C@H](O)[C@@H]3[C@]([C@H]1CC2)(C)CC[C@@H](C3)O)C |
| Standard InCHI | InChI=1S/C27H44O4/c1-15-5-10-27(30-14-15)16(2)24-23(31-27)13-20-18-12-22(29)21-11-17(28)6-8-25(21,3)19(18)7-9-26(20,24)4/h15-24,28-29H,5-14H2,1-4H3/t15-,16+,17+,18-,19+,20+,21-,22+,23+,24+,25-,26+,27-/m1/s1 |
| Standard InCHIKey | PZNPHSFXILSZTM-JUGSJECZSA-N |
| External Identifiers | ChEMBL [CHEMBL2047364]; PubChem [12303065]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC3853
Formula: C27H42O4
Ingredient ID: TCMC3853
| Common Name | Ruscogenin |
| IUPAC Name | (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,14R,16R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-14,16-diol |
| Canonical SMILES | C[C@@H]1CC[C@@]2(OC1)O[C@@H]1[C@H]([C@@H]2C)[C@@]2([C@@H](C1)[C@@H]1CC=C3[C@]([C@H]1CC2)(C)[C@H](O)C[C@@H](C3)O)C |
| Standard InCHI | InChI=1S/C27H42O4/c1-15-7-10-27(30-14-15)16(2)24-22(31-27)13-21-19-6-5-17-11-18(28)12-23(29)26(17,4)20(19)8-9-25(21,24)3/h5,15-16,18-24,28-29H,6-14H2,1-4H3/t15-,16+,18-,19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1 |
| Standard InCHIKey | QMQIQBOGXYYATH-IDABPMKMSA-N |
| External Identifiers | ChEMBL [CHEMBL1169820]; PubChem [441893]; |
| Reference of Component-Ingredient Pair | 16957914 |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC3850
Formula: C27H44O4
Ingredient ID: TCMC3850
| Common Name | Gitogenin |
| IUPAC Name | (1R,2S,4S,5'R,6R,7S,8R,9S,12S,13S,15R,16R,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-15,16-diol |
| Canonical SMILES | C[C@@H]1CC[C@@]2(OC1)O[C@@H]1[C@H]([C@@H]2C)[C@@]2([C@@H](C1)[C@@H]1CC[C@@H]3[C@]([C@H]1CC2)(C)C[C@H]([C@@H](C3)O)O)C |
| Standard InCHI | InChI=1S/C27H44O4/c1-15-7-10-27(30-14-15)16(2)24-23(31-27)12-20-18-6-5-17-11-21(28)22(29)13-26(17,4)19(18)8-9-25(20,24)3/h15-24,28-29H,5-14H2,1-4H3/t15-,16+,17+,18-,19+,20+,21-,22-,23+,24+,25+,26+,27-/m1/s1 |
| Standard InCHIKey | FWCXELAAYFYCSR-RYKNUXCGSA-N |
| External Identifiers | ChEMBL [CHEMBL1770687]; PubChem [441887]; |
| Reference of Component-Ingredient Pair | 20270112 |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC2524
Formula: C34H28Br4N4O8
Ingredient ID: TCMC2524
| Common Name | Bastadin 13 |
| IUPAC Name | n.a. |
| Canonical SMILES | O/N=C/1Cc2cc(Br)c(c(c2)Oc2c(Br)cc(cc2Br)C/C(=NO)/C(=NCCc2ccc(Oc3cc(CCN=C1O)ccc3O)c(Br)c2)O)O |
| Standard InCHI | InChI=1S/C34H28Br4N4O8/c35-21-9-17-2-4-28(21)49-29-15-18(1-3-27(29)43)6-8-40-34(46)26(42-48)14-20-10-22(36)31(44)30(16-20)50-32-23(37)11-19(12-24(32)38)13-25(41-47)33(45)39-7-5-17/h1-4,9-12,15-16,43-44,47-48H,5-8,13-14H2,(H,39,45)(H,40,46)/b41-25+,42-26+ |
| Standard InCHIKey | XNGIESBQQZJDTL-RIVOPQIESA-N |
| External Identifiers | ChEMBL [CHEMBL445712]; PubChem [23426999]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC2512
Formula: C12H8S3
Ingredient ID: TCMC2512
| Common Name | Alpha-Terthienyl |
| IUPAC Name | 2,5-dithiophen-2-ylthiophene |
| Canonical SMILES | c1csc(c1)c1ccc(s1)c1cccs1 |
| Standard InCHI | InChI=1S/C12H8S3/c1-3-9(13-7-1)11-5-6-12(15-11)10-4-2-8-14-10/h1-8H |
| Standard InCHIKey | KXSFECAJUBPPFE-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL90017]; PubChem [65067]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1024 | Tribulus terrestris | Ji Li | 蒺藜 |
| TCMH1331 | Rhaponticum uniflorum | Lou Lu | 漏芦 |
| TCMH1503 | Eclipta prostrata | Mo Han Lian | 墨旱莲 |
| TCMH2733 | Trachycarpus fortunei | Zong Ban | 棕板 |
| TCMH2734 | Trachycarpus fortunei | Zong Ban Tan | 棕板炭 |
| TCMH2738 | Trachycarpus fortunei | Zong Lv Pi | 棕榈皮 |
| TCMH2740 | Trachycarpus fortunei | Zong Lv Zi | 棕榈子 |
| TCMH320 | Tribulus terrestris | Ci Ji Li | 刺蒺藜 |
| TCMH73 | Tribulus terrestris | Bai Ji Li | 白蒺藜 |
| TCMH800 | Herba ecliptae prostratae | Han Lian Cao | 旱莲草 |
Showing 1 to 10 of 10 entries
Ingredient ID: TCMC2500
Formula: C24H28N2O6
Ingredient ID: TCMC2500
| Common Name | Terrestribisamide |
| IUPAC Name | (E)-3-(4-hydroxy-3-methoxyphenyl)-N-[4-[[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]amino]butyl]prop-2-enamide |
| Canonical SMILES | COc1cc(/C=C/C(=NCCCCN=C(/C=C/c2ccc(c(c2)OC)O)O)O)ccc1O |
| Standard InCHI | InChI=1S/C24H28N2O6/c1-31-21-15-17(5-9-19(21)27)7-11-23(29)25-13-3-4-14-26-24(30)12-8-18-6-10-20(28)22(16-18)32-2/h5-12,15-16,27-28H,3-4,13-14H2,1-2H3,(H,25,29)(H,26,30)/b11-7+,12-8+ |
| Standard InCHIKey | CHEMZHJQHCVLFI-MKICQXMISA-N |
| External Identifiers | ChEMBL [CHEMBL1088758]; PubChem [5321825]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC1767
Formula: C18H19NO4
Ingredient ID: TCMC1767
| Common Name | N-Trans-Feruloyl Tyramine |
| IUPAC Name | (E)-3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide |
| Canonical SMILES | COc1cc(/C=C/C(=NCCc2ccc(cc2)O)O)ccc1O |
| Standard InCHI | InChI=1S/C18H19NO4/c1-23-17-12-14(4-8-16(17)21)5-9-18(22)19-11-10-13-2-6-15(20)7-3-13/h2-9,12,20-21H,10-11H2,1H3,(H,19,22)/b9-5+ |
| Standard InCHIKey | NPNNKDMSXVRADT-WEVVVXLNSA-N |
| External Identifiers | ChEMBL [CHEMBL206555]; PubChem [5280537]; |
| Reference of Component-Ingredient Pair | 11509987 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1005 | Cannabis sativa | Huo Ma Ren | 火麻仁 |
| TCMH1024 | Tribulus terrestris | Ji Li | 蒺藜 |
| TCMH1185 | Lycium chinense | Gou Qi | 枸杞 |
| TCMH1186 | Lycium chinense | Gou Qi Zi | 枸杞子 |
| TCMH1265 | Chenopodium album | Li | 藜 |
| TCMH1275 | Nelumbo nucifera | Lian Zi | 莲子 |
| TCMH1276 | Nelumbo nucifera | Lian Zi Xin | 莲子心 |
| TCMH1380 | Humulus japonicus | Lv Cao | 葎草 |
| TCMH1396 | Portulaca oleracea | Ma Chi Xian | 马齿苋 |
| TCMH1409 | Cannabis sativa | Ma Ren | 麻仁 |
Showing 1 to 10 of 41 entries
Ingredient ID: TCMC1310
Formula: C12H10N2O
Ingredient ID: TCMC1310
| Common Name | Harmol |
| IUPAC Name | 1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one |
| Canonical SMILES | O=c1ccc2c(c1)[nH]c1c2cc[nH]c1C |
| Standard InCHI | InChI=1S/C12H10N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-6,13-14H,1H3 |
| Standard InCHIKey | LBBJNGFCXDOYMQ-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL486817]; PubChem [68094]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC1309
Formula: C13H12N2O
Ingredient ID: TCMC1309
| Common Name | Harmine |
| IUPAC Name | 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole |
| Canonical SMILES | COc1ccc2c(c1)[nH]c1c2ccnc1C |
| Standard InCHI | InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3 |
| Standard InCHIKey | BXNJHAXVSOCGBA-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL269538]; PubChem [5280953]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC1308
Formula: C12H10N2
Ingredient ID: TCMC1308
| Common Name | Harman |
| IUPAC Name | 1-methyl-9H-pyrido[3,4-b]indole |
| Canonical SMILES | Cc1nccc2c1[nH]c1c2cccc1 |
| Standard InCHI | InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3 |
| Standard InCHIKey | PSFDQSOCUJVVGF-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL12014]; PubChem [5281404]; |
| Reference of Component-Ingredient Pair | 29069497 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1024 | Tribulus terrestris | Ji Li | 蒺藜 |
| TCMH2083 | Viola philippica | Tian Di Ding | 甜地丁 |
| TCMH2226 | Stigma croci | Xi Hong Hua | 西红花 |
| TCMH2370 | Commelina communis | Ya Zhi Cao | 鸭跖草 |
| TCMH2554 | Polygala tenuifolia | Yuan Zhi | 远志 |
| TCMH2555 | Polygala tenuifolia | Yuan Zhi Jin Gao | 远志浸膏 |
| TCMH2556 | Polygala tenuifolia | Yuan Zhi Liu Jin Gao | 远志流浸膏 |
| TCMH320 | Tribulus terrestris | Ci Ji Li | 刺蒺藜 |
| TCMH695 | Uncaria rhynchophylla | Gou Teng | 钩藤 |
| TCMH73 | Tribulus terrestris | Bai Ji Li | 白蒺藜 |
Showing 1 to 10 of 10 entries
Ingredient ID: TCMC1173
Formula: C10H10O4
Ingredient ID: TCMC1173
| Common Name | Ferulic Acid |
| IUPAC Name | (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid |
| Canonical SMILES | COc1cc(/C=C/C(=O)O)ccc1O |
| Standard InCHI | InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ |
| Standard InCHIKey | KSEBMYQBYZTDHS-HWKANZROSA-N |
| External Identifiers | ChEMBL [CHEMBL32749]; PubChem [445858]; |
| Reference of Component-Ingredient Pair | 25130191 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1000 | Foeniculum vulgare | Hui Xiang | 茴香 |
| TCMH101 | Chelidonium majus | Bai Qu Cai | 白屈菜 |
| TCMH1024 | Tribulus terrestris | Ji Li | 蒺藜 |
| TCMH1033 | Centella asiatica | Ji Xue Cao | 积雪草 |
| TCMH1064 | Coptis chinensis | Jiang Huang Lian | 姜黄连 |
| TCMH108 | Perilla frutescens | Bai Su Zi | 白苏子 |
| TCMH1117 | Rhizoma fagopyri cymosi | Jin Qiao Mai | 金荞麦 |
| TCMH1127 | Lonicera japonica | Jin Yin Hua | 金银花 |
| TCMH1128 | Lonicera japonica | Jin Yin Hua Ti Qu Ye | 金银花提取液 |
| TCMH1146 | Oryza sativa | Jing Mi | 粳米 |
Showing 1 to 10 of 158 entries
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC1173 | C10H10O4 | Ferulic Acid | 194.06 | -0.3908 | 2.12 | 1.231 | 2 | 2 | 66.76 | 6 | 1 | 14 | 0 |
| TCMC1308 | C12H10N2 | Harman | 182.08 | 0.0191 | 2.56 | 2.968 | 2 | 1 | 28.68 | 1 | 3 | 14 | 0 |
| TCMC1309 | C13H12N2O | Harmine | 212.09 | -0.0327 | 2.56 | 2.313 | 2 | 1 | 37.91 | 3 | 3 | 16 | 0 |
| TCMC1310 | C12H10N2O | Harmol | 198.08 | -0.8687 | 2.45 | 2.112 | 3 | 2 | 44.89 | 1 | 3 | 15 | 0 |
| TCMC1767 | C18H19NO4 | N-Trans-Feruloyl Tyramine | 313.13 | -0.6499 | 2.89 | 3.109 | 2 | 3 | 82.28 | 10 | 2 | 23 | 0 |
| TCMC2500 | C24H28N2O6 | Terrestribisamide | 440.19 | -1.4664 | 3.22 | 3.384 | 4 | 4 | 124.1 | 17 | 2 | 32 | 1 |
| TCMC2512 | C12H8S3 | Alpha-Terthienyl | 247.98 | 1.7718 | 2.45 | 4.693 | 0 | 0 | 84.72 | 2 | 3 | 15 | 0 |
| TCMC2524 | C34H28Br4N4O8 | Bastadin 13 | 935.86 | 1.875 | 3.44 | 8.378 | 4 | 6 | 189.28 | 10 | 4 | 50 | 2 |
| TCMC3850 | C27H44O4 | Gitogenin | 432.3239599 | 0.1181 | 3.99 | 6.494 | 4 | 2 | 58.92 | 0 | 6 | 31 | 1 |
| TCMC3853 | C27H42O4 | Ruscogenin | 430.3083098 | -0.296 | 3.99 | 4.378 | 4 | 2 | 58.92 | 0 | 6 | 31 | 0 |
Showing 1 to 10 of 11 entries
Download Data
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