| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ABCG2, ACHE, ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CDK6, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GAA, GBA, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MIF, NISCH, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PTGS1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
24.0833 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ABCG2, AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GPER1, GRIK5, GRM5, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MMP2, MMP9, NR3C1, PIK3CA, POLB, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
17.042 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, GBA, GPER1, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HTR1B, HTR5A, IGF1R, INSR, MAOB, MMP2, MMP9, NR3C1, PIK3CA, POLB, PPARA, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
17.0019 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, F10, F3, FLT3, GBA, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP9, NISCH, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.5157 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F10, F3, FLT3, GBA, GPER1, GPR35, GRM1, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.4299 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F10, F3, FLT3, GBA, GPER1, GPR35, GRM1, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.3835 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GPER1, GRIK5, GRM5, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MMP2, NR3C1, PIK3CA, POLB, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
16.3615 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, F10, F3, FLT3, GBA, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP9, NISCH, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.3379 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRB1, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
16.0535 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, APP, CBR1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD2, EGFR, ERBB2, ESR1, FABP3, FABP4, FDPS, FUCA1, FUT7, GBA, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TBXAS1, TRPV1 |
15.9248 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, FABP3, FDPS, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSD17B3, HSPA1A, HTR2B, HTR2C, MIF, NISCH, PDE5A, PIK3CA, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR, XDH |
15.0995 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.0064 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.0064 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, NISCH, PTGS2 |
13.8713 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, NISCH, PTGS2 |
13.8713 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRB1, CHRM2, CNR1, DRD1, DRD2, DRD3, DRD5, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
13.8713 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, F10, F3, FLT3, GPER1, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.8472 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, ERBB2, F10, F3, FLT3, GPER1, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MCL1, MET, MIF, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
13.8204 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
AKR1C3, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FLT3, GBA, GPER1, HSD11B2, HTR1B, HTR5A, MAOB, NR3C1, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
13.6899 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, DYRK2, DYRK3, EGFR, ERBB2, ESR1, F10, F3, FLT3, GBA, GPER1, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
13.5268 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, ADRB1, AKR1B1, ALOX12, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GPER1, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, INSR, MCL1, MET, PIK3CA, PIK3CB, POLA1, POLB, SMAD3, SRC, TERT, TRPV1 |
13.4525 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX12, APP, AR, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, F3, FABP3, FLT3, GPER1, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, PDE5A, PGR, PIM1, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
13.3186 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GBA, GPER1, GPR35, GRIK5, GRM1, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
13.2165 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FLT3, GBA, GPER1, GRM5, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, KIT, MAOB, MMP2, NR3C1, PPARA, PTGS2, SMAD3, SRC, TEK, TRPV1 |
13.0171 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CACNA1C, CDK6, CNR1, DRD1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PIK3CB, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
12.4244 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM2, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
12.3412 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGS1, PTGS2, TBXAS1 |
12.1989 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HASPIN, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
12.1697 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DAO, DRD1, DRD2, DRD3, FDPS, GBA, GBA2, HIF1A, HMGCR, HSD17B3, HTR1A, MAOA, MAOB, TYR |
11.9522 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, ABCG2, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, GBA, HMGCR, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KDR, MAOB, NR3C1, POLB, PTGS2, SRC, TRPV1 |
11.9522 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGS1, PTGS2, TBXAS1 |
11.7752 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESRRB, FABP3, FABP4, FLT3, GBA, GPER1, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.7333 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESRRB, FABP3, FABP4, FLT3, GBA, GPER1, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.6159 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GBA, GPER1, GPR35, GRIK5, GRM1, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
11.6147 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CACNA1C, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GAA, GBA, GPER1, GRM1, GRM5, GRM8, HIF1A, HMGCR, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IGF1R, INSR, KIT, MCL1, MET, MGAM, MMP1, MMP12, MMP2, MMP9, PDE5A, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
11.5895 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ERBB2, ESRRB, FABP3, FLT3, GBA, GPER1, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.5586 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ERBB2, ESRRB, FABP3, FLT3, GBA, GPER1, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.5586 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
AKR1C3, ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
11.4316 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRB1, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CA1, CA2, CACNA1C, CDK6, CHRM2, CNR1, CNR2, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, MMP2, MMP9, NISCH, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
11.4316 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AKR1C3, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DYRK3, EGFR, ESR1, F3, FLT3, GBA, GLO1, GPER1, GRIK5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MCL1, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.3972 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AKR1C3, ALOX12, AR, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, ESR1, F3, FLT3, GPER1, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, PIM1, PTGS2, TEK, TERT |
11.3972 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CACNA1C, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DYRK2, EGFR, ERBB2, F10, F3, GPER1, GPR35, GRIK5, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MET, MIF, MMP12, MMP9, NISCH, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
11.3616 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AKR1C3, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DYRK3, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MCL1, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.2327 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD2, EGFR, ERBB2, FABP3, FABP4, FDPS, FUCA1, FUT7, GBA, GBA2, HMGCR, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, TBXAS1 |
11.1063 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, PTGS2 |
10.9891 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRB1, AKR1C3, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GPER1, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MET, MIF, MMP12, MMP9, NR3C1, PDE5A, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.8961 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRB1, AKR1C3, AR, AXL, BCL2, CACNA1C, CHRM2, CNR1, DRD1, DRD2, DRD3, DRD5, ESR2, GBA, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, PTGS2, SLC1A1, TEK, TRPV1 |
10.8852 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK2, EGFR, ERBB2, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GBA, GPER1, GRIK5, GRM1, GRM5, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MIF, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
10.8822 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AKR1C3, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, GPER1, HSD11B2, HTR1B, HTR5A, INSR, KIT, MAOB, NR3C1, PPARA, PTGS2, SRC, TEK, TRPV1 |
10.8599 |
|
[BP] GO:0033993 |
response to lipid
|
AKR1C3, ALPL, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, GPER1, HSD11B2, HSD17B2, HTR1B, HTR5A, MAOB, NR3C1, PTGS2, RORC, SRC, TYR |
10.6969 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESRRA, F10, F3, FABP4, FLT3, GPER1, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP2, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.6586 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, AKR1B1, ALOX12, APP, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, GBA, GPER1, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, SMAD3, TRPV1 |
10.6586 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HASPIN, HIF1A, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MET, MGAM, MIF, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
10.6255 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, AKR1C3, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, ESR1, FDPS, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
10.5699 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRB1, DRD1, DRD5, EGFR, GPER1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SRC, TEK |
10.558 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GPER1, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MET, MIF, MMP12, MMP9, NR3C1, PDE5A, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.5495 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GBA, GPER1, GRIK5, GRM5, HIF1A, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, PIK3CA, PTGS2, RORC, SMAD3, SRC, TRPV1 |
10.3501 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GBA, GPER1, GRIK5, GRM5, HIF1A, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR3C1, PIK3CA, PTGS2, RORC, SMAD3, SRC, TERT, TRPV1 |
10.32 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, AKR1C3, CACNA1C, CNR1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, GPER1, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HTR1A, HTR2A, HTR2C |
10.1473 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AKR1C3, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DYRK3, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MCL1, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
10.1372 |
|
[BP] GO:0099536 |
None
|
CHRM2, CNR1, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
10.1372 |
|
[BP] GO:0099537 |
None
|
CHRM2, CNR1, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
10.1372 |
|
[BP] GO:0097756 |
None
|
ADORA1, DRD5, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
10.03 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRB1, AKR1C3, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GPER1, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MET, MIF, MMP12, MMP9, NR3C1, PDE5A, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.99354 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F10, F3, GPER1, HIF1A, HTR1D, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NISCH, PTGS2, SMAD3, SRC, TEK, TERT |
9.92369 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, GAA, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, MAOA, MAOB, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
9.86329 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AKR1C3, AXL, DRD2, DRD3, EGFR, ERBB2, F10, F3, GPER1, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
9.64356 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRB1, DRD1, DRD5, EGFR, GPER1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
9.61495 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRB1, DRD1, DRD5, EGFR, GPER1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
9.61495 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.50446 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGS1, PTGS2, TBXAS1 |
9.46088 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPER1, GPR35, GRM3, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MAOB, MCL1, MET, MIF, MMP12, MMP9, NISCH, NR3C1, PDE5A, PGR, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.45726 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, CLK1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
9.43296 |
|
[BP] GO:0007268 |
None
|
CHRM2, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
9.39558 |
|
[BP] GO:0098916 |
None
|
CHRM2, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
9.39558 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CBR1, CDC25B, CDK6, CES2, CHRM2, CLK1, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
9.38808 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, ERBB2, F10, F3, GPER1, HIF1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NISCH, PTGS2, SMAD3, SRC, TEK, TERT |
9.37379 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GBA, GPER1, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
9.36222 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, CLK1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
9.35345 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DRD2, EGFR, ERBB2, FLT3, GPER1, GRM1, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, PDE5A, PIK3CB, PTPN1, SRC, TEK, XDH |
9.35345 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX12, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPER1, GPR35, GRM3, GRM8, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MAOB, MCL1, MET, MIF, MMP12, MMP9, NISCH, NR3C1, PDE5A, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.3175 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRB1, DRD1, DRD5, EGFR, GPER1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
9.29723 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRB1, DRD1, DRD5, EGFR, GPER1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
9.25664 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, DYRK3, EGFR, GBA, GLO1, HIF1A, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MCL1, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.25664 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CACNA1C, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, ERBB2, F10, F3, GPER1, HIF1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NISCH, PTGS2, SMAD3, SRC, TEK, TERT |
9.23932 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRB1, AR, CHRM2, CNR1, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, SLC1A1, TEK |
9.11446 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK3, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, GPR35, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MCL1, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
9.11446 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK3, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, GPR35, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MCL1, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
9.07844 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FDPS, FLT3, HASPIN, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, POLB, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
8.90028 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, AKR1C3, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.89676 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
8.86435 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRB1, DRD1, DRD5, EGFR, GPER1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SRC, TEK |
8.86353 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRB1, AR, CACNA1C, CHRM2, CNR1, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, SLC1A1, TEK |
8.86353 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, DYRK3, EGFR, GLO1, HIF1A, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, KIT, MCL1, MET, MIF, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.8538 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ERBB2, ESRRB, FLT3, GPER1, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
8.8538 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, DYRK2, EGFR, ERBB2, ESR1, FABP4, FLT3, GBA, GPER1, GRIK5, GRM1, GRM5, HIF1A, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MCL1, MIF, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, POLA1, POLB, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
8.77778 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, AKR1C3, CNR1, CYP1A1, DRD3, FABP3, FDPS, FLT3, GPER1, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, KIT, PPARA, PTGS2, RORC, SRC, TEK |
8.76289 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CACNA1C, CBR1, CDC25B, CDK6, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, DYRK1B, DYRK3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSD11B1, HSD17B2, HSD17B3, HTR2A, HTR2B, HTR5A, INSR, KDR, KIT, MAOB, MCL1, MET, MIF, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
8.74937 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, ADRB1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, GBA, GRM1, HIF1A, HMGCR, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, KIT, MMP2, POLB, PPARA, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
8.71504 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, GPER1, HIF1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NISCH, PTGS2, SMAD3, SRC, TEK, TERT |
8.63206 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DRD2, DUSP3, EGFR, ERBB2, FLT3, GBA, GPER1, GRM1, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, PDE5A, PIK3CB, PTPN1, SRC, TEK, XDH |
8.61689 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRB1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, F10, F3, FLT3, GBA, GPER1, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, MMP12, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.61678 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AKR1C3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, HIF1A, KDR, KIT, MAOB, MMP9, PTGS2, SRC, TERT |
8.60722 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX12, ALOX15, AR, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, DYRK3, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, HIF1A, HMGCR, HSPA1A, IGF1R, MCL1, MET, MIF, MMP12, MMP9, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
8.58113 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CYP19A1, DRD1, DRD2, DRD3, DYRK2, EGFR, ERBB2, GPER1, GPR35, GRIK5, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, MAOB, MIF, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
8.5724 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRB1, AKR1C3, APP, CA2, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, SRC |
8.48504 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, APEX1, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GAA, GPER1, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, MCL1, PIK3CA, PIK3CB, POLA1, SMAD3, TRPV1 |
8.47515 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
AKR1C3, ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
8.45397 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GPER1, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, PDE5A, PGR, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.30072 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FDPS, FLT3, HASPIN, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, POLB, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
8.29516 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GBA, GPER1, GRM1, GRM3, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.27238 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRB1, AKR1B1, AKR1C3, APP, BCL2, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, GPER1, GRM1, GRM5, GRM8, HIF1A, HMGCR, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, KIT, PDE5A, PIK3CA, PTGS2, SRC, TEK, TRPV1, TYR |
8.23654 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, GRM1, GRM5, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, KIT, PPARA, PTGS2, TRPV1 |
8.14765 |
|
[BP] GO:1900542 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, ESRRB, GPER1, GRM3, GRM8, HIF1A, HTR1B, HTR1E, HTR2A, INSR, PDE5A, PPARA |
8.07925 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, HMGCR, HTR1B, HTR1D, KDR, MAOB, POLB, SRC |
8.03205 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ERBB2, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
8.01842 |
|
[BP] GO:0006140 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, ESRRB, GPER1, GRM3, GRM8, HIF1A, HTR1B, HTR1E, HTR2A, INSR, PDE5A, PPARA |
7.89973 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CES2, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HASPIN, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.8803 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ERBB2, ESRRB, FABP4, FLT3, GBA, GPER1, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
7.85884 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, GPER1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
7.8289 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, GPER1, HTR2A, HTR2B, HTR2C, KDR, SRC, TRPV1 |
7.81405 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2, DRD2, HTR1B, NISCH |
7.79576 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, CHRM2, DRD2, DRD3, EGFR, GAA, GBA, GPER1, GPR35, GRM1, HCAR2, HTR2A, HTR2C, KIT, PDE5A, PTGS2, SLC1A1, SMAD3, TRPV1 |
7.70342 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, DYRK3, EGFR, GLO1, HIF1A, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MCL1, MIF, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
7.69017 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, ALOX12, APP, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, DYRK1A, DYRK3, EGFR, ESR1, F3, FABP4, GBA, GPER1, HIF1A, HMGCR, HSPA1A, IGF1R, MCL1, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
7.62789 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRB1, AR, CNR1, DRD2, DRD3, DRD5, HSD11B2, NISCH, PPARA, PTGS1, PTGS2, SMAD3 |
7.59506 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, GPER1, GRIK5, HTR1A, INSR, MAOA, MAOB, PTGS2, SLC1A1, SMAD3, TRPV1 |
7.57159 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PPARA, PTGS1, PTGS2, TBXAS1 |
7.55528 |
|
[BP] GO:0048545 |
response to steroid hormone
|
AKR1C3, ALPL, AR, BCL2, CA2, EGFR, FLT3, GBA, GPER1, HSD11B2, HTR1B, MAOB, NR3C1, PTGS2, SRC |
7.5307 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, GBA, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PDE5A, PIK3CB, PTPN1, SRC |
7.5307 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AKR1C3, APEX1, APP, AR, AXL, CDK6, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ESR1, GPER1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PTGS2, RORC, SRC, TRPV1 |
7.50718 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AKR1C3, AXL, EGFR, ERBB2, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
7.50473 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, DRD1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, SRC, TEK, TNKS |
7.49669 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
7.48661 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRB1, ALOX12, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CHRM2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F3, GAA, GBA, GPER1, GPR35, GRM1, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PDE5A, PIK3CA, PIM1, PTGS2, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
7.47884 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GPER1, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TRPV1, TYR |
7.43371 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, FLT3, GBA, GPER1, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
7.41362 |
|
[BP] GO:0031960 |
response to corticosteroid
|
AKR1C3, ALPL, BCL2, EGFR, FLT3, GBA, GPER1, HSD11B2, HTR1B, MAOB, NR3C1, PTGS2, SRC |
7.41362 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, GPER1, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.37919 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, PIK3CB, PTGS2, TNKS, TNKS2 |
7.36761 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, SMAD3, TRPV1 |
7.35532 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
AKR1C3, ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FLT3, GPER1, NR3C1, PTGS2, RORC, SRC, TRPV1 |
7.33988 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, AKR1C3, ALOX12, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, FDPS, GBA, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, MIF, PIK3CA, PIK3CB, PTGS1, PTGS2 |
7.24671 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
7.21943 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CLK1, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, PIM1, SRC, TEK |
7.1997 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DAO, DRD1, DRD2, DRD3, HTR1A, MAOA, MAOB, TYR |
7.17355 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, GPER1, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
7.17355 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, DUSP3, EGFR, ERBB2, GPER1, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PTPN1, SRC, TEK |
7.16978 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, GPER1, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
7.13606 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, GBA, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.13486 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRB1, ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, GBA, GPER1, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, KDR, KIT, MET, MIF, MMP12, MMP9, PDE5A, PIM1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
7.11587 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
7.06672 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, GBA, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.04448 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AKR1C3, AR, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, HIF1A, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, PIK3CA, POLB, PPARA, PTPRS, SMAD3, SRC, TEK, TYR |
7.03086 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DRD3, DUSP3, DYRK1A, DYRK3, ESR1, GBA, GPER1, HIF1A, HMGCR, HSPA1A, IGF1R, MCL1, MET, MIF, MMP9, PTGS2, PTPN1, SRC, XDH |
7.02725 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, AKR1C3, APEX1, APP, AR, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FLT3, GPER1, GRM5, HTR1B, IGF1R, INSR, KIT, MMP2, NR3C1, PTGS2, SMAD3, SRC, TRPV1 |
7.00698 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
7.00374 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
6.98648 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, GPER1, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.95444 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.89682 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
6.89376 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM2, CLK1, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, GAA, GBA, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.88517 |
|
[BP] GO:0032787 |
None
|
AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, HIF1A, MIF, PPARA, PTGS1, PTGS2, TBXAS1 |
6.84107 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
6.83332 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD1, DRD2, DRD3, DRD5, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, GPER1, HIF1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
6.82898 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, SRC, TEK |
6.81666 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GPER1, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TRPV1, TYR |
6.80711 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, HTR2A, HTR2B, HTR2C, MIF, SRC, TNKS, TNKS2, TRPV1 |
6.77044 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
6.76255 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
6.74459 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD1, DRD2, DRD5, HTR1B, HTR2A, PTGS2 |
6.73765 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
6.73765 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ALOX12, APP, BCL2, DRD1, EGFR, F10, F3, GPER1, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PTGS2, SMAD3, SRC, TEK, TERT |
6.72661 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CLK1, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, GBA, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.70088 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, DNMT1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GPER1, GRM3, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MCL1, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
6.69933 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
6.67597 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CES2, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HASPIN, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.65838 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, AKR1C3, CSNK2A1, DAO, DRD1, DRD2, DRD3, GBA, HTR1A, MAOA, MAOB |
6.65838 |
|
[BP] GO:0042310 |
None
|
DRD5, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
6.65822 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
6.65822 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, ADRB1, AKR1B1, ALOX12, DRD1, DRD2, GBA, HTR2A, MET, PIK3CA, TRPV1 |
6.62747 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRB1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CLK1, CNR1, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, GBA, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.59225 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, FABP4, FLT3, GBA, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
6.58894 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.58498 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3, TRPV1 |
6.58307 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD1, DRD2, DRD3, DRD5, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, GPER1, HIF1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
6.53426 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.46055 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, AKR1C3, FUCA1, GBA, GBA2 |
6.45659 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HIF1A, HMGCR, HTR2A, INSR, KIT, PTGS2 |
6.39291 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, ESR2, F3, FABP4, FLT3, GBA, GPER1, GPR35, GRM1, GRM3, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MET, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
6.38057 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, CYP3A4, FDPS, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.35328 |
|
[BP] GO:0010038 |
response to metal ion
|
AKR1C3, ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, HIF1A, KIT, MAOB, MMP9, PTGS2, TERT |
6.33394 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, HIF1A, HMGCR, HTR2A, INSR, KIT, PTGS2 |
6.3015 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, EGFR, GPER1, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, SRC, TEK |
6.28261 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, ADRB1, APP, AR, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ERBB2, ESR1, ESR2, F3, FLT3, GPER1, GRM1, GRM5, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KIT, MET, MIF, MMP9, PDE5A, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.25836 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, ALOX12, CNR2, CYP19A1, DRD1, DRD2, DRD3, GBA, GPER1, HMGCR, MIF, PPARA, PTPRS, SMAD3, TEK |
6.25764 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, AKR1C3, ALOX12, ALOX15, CYP19A1, CYP3A4, DAO, FDPS, GBA, HMGCR, HSD17B3, TYR |
6.25722 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, DRD1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TNKS |
6.21694 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, DYRK1A, EGFR, ESR1, HTR7, KIT, PGR, PPARA, RORC, SRC, TOP2A |
6.15878 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRB1, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK2, EGFR, ERBB2, GPER1, GRM5, HASPIN, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, NISCH, NUAK1, PIK3CA, PIK3CB, POLB, PTPN1, SRC, TEK |
6.15378 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
6.11478 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, DYRK1B, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, GAA, GBA2, HIF1A, HSD11B1, HSD17B2, HSD17B3, HTR5A, INSR, KDR, KIT, MAOB, MCL1, MMP9, PGR, PIK3CA, PIM1, POLB, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TYR |
6.08679 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, GRM5, HIF1A, HMGCR, INSR, KIT, PTGS2 |
6.02552 |
|
[BP] GO:0019371 |
None
|
AKR1C3, CBR1, PTGS1, PTGS2, TBXAS1 |
5.96233 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ALOX12, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, GBA, GPER1, HMGCR, KDR, MET, MIF, MMP12, PPARA, PTGS2, PTPRS, SMAD3, TEK |
5.95849 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PDE5A, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
5.9375 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2, HSD17B3 |
5.92479 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, APP, BCL2, CA2, CA7, CACNA1C, CNR1, DRD1, DRD2, DRD3, GPER1, GPR35, GRM5, HTR1A, HTR1B, HTR2A, MAOB, MIF, MMP9, PTGS2 |
5.9045 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PDE5A, PIK3CA, PIK3CB, PTPN1, SRC |
5.9045 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
5.9045 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CLK1, CNR1, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.89077 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD2, DRD3, GPR35, HTR1B, HTR2A, MAOB, MMP9, PTGS2 |
5.8793 |
|
[BP] GO:0030799 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, GRM3, GRM8, HTR1B, HTR1E, PDE5A |
5.84883 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRB1, APP, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ERBB2, ESR1, F3, FLT3, GPER1, GRM1, GRM5, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KIT, MIF, PDE5A, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.84541 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CACNA1C, CNR1, CYP19A1, DRD2, DRD3, EGFR, GPER1, GRIK5, HCAR2, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MAOB, MIF, MMP12, SRC, TRPV1 |
5.84406 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CACNA1C, CNR1, CNR2, DRD1, GBA, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
5.79882 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CACNA1C, CNR1, CYP19A1, DRD2, DRD3, EGFR, GPER1, GRIK5, HCAR2, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MAOB, MIF, MMP12, SRC |
5.74812 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PDE5A, PIK3CB, PTPN1, SRC |
5.70984 |
|
[BP] GO:0030814 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, GRM3, GRM8, HTR1B, HTR1E |
5.65021 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PDE5A, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
5.64962 |
|
[BP] GO:0007200 |
None
|
CHRM2, DRD1, DRD2, DRD5, ESR1, GRM5, HTR2A, HTR2B, HTR2C |
5.64455 |
|
[BP] GO:0045776 |
None
|
ADORA1, ADRB1, CNR1, DRD2, DRD3, DRD5, PPARA |
5.55372 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, TRPV1 |
5.54023 |
|
[BP] GO:0051588 |
None
|
DRD1, DRD2, DRD3, GPER1, GRIK5, HTR1A, HTR1B, HTR2C, MAOB |
5.52203 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, DAO, DRD1, DRD2, DRD3, EGFR, HSPA1A, MAOA, MAOB |
5.51907 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3, MAOA, MAOB |
5.48851 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3, MAOA, MAOB |
5.48851 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
AR, BCL2, DRD2, DRD3, DUSP3, DYRK1A, DYRK3, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, HIF1A, HMGCR, HSPA1A, IGF1R, MCL1, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
5.42666 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PPARA, PTGS2, SRC, TEK |
5.42435 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AR, AURKB, BCL2, CLK1, CYP1A1, EGFR, ERBB2, ESR1, FLT3, HTR1A, KIT, MET, MIF, PIK3CB, PIM1, POLA1, SRC, TEK, TYR |
5.40912 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MCL1, MIF, MMP9, PTGS2, PTPN1, SRC |
5.33181 |
|
[BP] GO:0045913 |
None
|
DYRK2, ESRRB, GPER1, HIF1A, HTR2A, INSR, PPARA, SRC |
5.33181 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, CYP1A1, CYP1A2, CYP3A4, DAO, DRD1, DRD2, DRD3, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUCA1, FUT7, GBA, GBA2, GLO1, HASPIN, HIF1A, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE5A, PIK3CA, PIM1, POLB, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.29533 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, ERBB2, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PDE5A, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
5.28314 |
|
[BP] GO:0042417 |
None
|
DAO, DRD1, DRD2, DRD3, MAOA, MAOB |
5.27861 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, POLB, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
5.22242 |
|
[BP] GO:0030817 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, GRM3, GRM8, HTR1B |
5.22242 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, HIF1A, HMGCR, KIT |
5.19387 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD5, DYRK2, EGFR, ERBB2, GBA, GPER1, HIF1A, HSD11B2, HSPA1A, HTR1A, HTR2C, KIT, MCL1, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
5.18084 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A, HMGCR, KIT |
5.17299 |
|
[BP] GO:0006939 |
None
|
DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, TRPV1 |
5.17299 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, SRC, TEK |
5.15266 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, GBA, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PDE5A, PIK3CB, PTPN1, SRC |
5.14874 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GPER1, GRM5, HTR1B, IGF1R, INSR, MMP2, PTGS2, SRC, TRPV1 |
5.14419 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CLK1, CSNK2A1, DRD1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, F10, FLT3, HASPIN, IGF1R, INSR, KDR, KIT, MET, SRC, TEK, TNKS, TOP2A |
5.10643 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CACNA1C, CNR1, DRD2, DRD3, DYRK2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HMGCR, HTR2B, HTR2C, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC |
5.10297 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, ERBB2, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PDE5A, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
5.1023 |
|
[BP] GO:0001659 |
None
|
ADORA1, ADRB1, DRD1, DRD2, HTR2A, TRPV1 |
5.02397 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
5.02397 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, ERBB2, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PDE5A, PIK3CA, PIK3CB, PTPN1, SRC |
5.02397 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
4.99169 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTGS2, TERT |
4.986 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, APP, AR, AURKB, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
4.96821 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, INSR, MIF, MMP12, PTGS2, SMAD3, SRC, TERT, TRPV1 |
4.96796 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
AKR1C3, APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GBA, GPER1, GRM3, GRM8, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MCL1, MET, MIF, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.94724 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRB1, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CLK1, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MAOB, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.94724 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CACNA1C, CNR1, CYP19A1, DRD2, EGFR, GPER1, HCAR2, HIF1A, HMGCR, HTR1A, HTR2A, HTR2C |
4.92284 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, DRD5, EGFR, ERBB2, PPARA, SMAD3 |
4.90466 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A, HMGCR, KIT |
4.89757 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM2, CLK1, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, GAA, GBA, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MET, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.86491 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT |
4.85392 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRB1, ALOX15, DRD1, DRD5, EGFR, GPER1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
4.78624 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, GBA, HTR1B, NR3C1 |
4.78321 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GPER1, GRM5, HTR1B, IGF1R, INSR, MMP2, PTGS2, SRC, TRPV1 |
4.70647 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, NQO2, PTGS1, RORC |
4.70267 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GBA2, GLO1, HIF1A, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
4.70267 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRB1, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, GPER1, GRM5, HTR2B, HTR5A, KDR |
4.60857 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, HTR1B, KDR, NR3C1, PTGS2, SRC, TRPV1 |
4.59274 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX12, ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
4.57286 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1C3, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM2, CLK1, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOB, MCL1, MET, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.56707 |
|
[BP] GO:0030802 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, GRM3, GRM8, HTR1B |
4.55378 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
CACNA1C, DRD1, DRD2, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
4.54805 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.54235 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.54235 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD1, DRD2, EGFR, GPER1, PTGS2 |
4.49838 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DNMT1, DRD2, DRD3, ESR1, GBA, GPER1, HIF1A, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.49737 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.48277 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.43935 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CACNA1C, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HMGCR, HTR2B, HTR2C, MIF, MMP12, SRC |
4.4162 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GBA2, GLO1, HIF1A, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
4.41158 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR, FDPS, HMGCR |
4.38712 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GPER1, GRM5, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
4.34015 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5 |
4.33659 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PDE5A, PIK3CB, PTPN1, SRC |
4.31303 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, GPER1, HMGCR, HTR1B, MMP2, MMP9, PTGS2, TERT |
4.30489 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, DYRK2, EGFR, ERBB2, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MCL1, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
4.30369 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ERBB2, GPER1, MIF, MMP12, PDE5A, PTPRS |
4.29812 |
|
[BP] GO:1900371 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, GRM3, GRM8, HTR1B |
4.27996 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AKR1C3, AOX1, AURKB, BACE1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, HSPA1A, MAOA, MAOB, MGAM, MMP1, MMP12, MMP2, MMP9, PDE5A, PIK3CB, SRC, XDH |
4.25753 |
|
[BP] GO:0030808 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, GRM3, GRM8, HTR1B |
4.25526 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRB1, ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F3, GPER1, HIF1A, HMGCR, HTR2A, HTR2C, INSR, KDR, KIT, MIF, NUAK1, PDE5A, PIK3CA, PIM1, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
4.25515 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, DYRK3, EGFR, HIF1A, HMGCR, HSPA1A, IGF1R, MCL1, MET, MIF, NUAK1, PTGS2, PTPN1, PTPRS, TERT, XDH |
4.24447 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HIF1A, HSPA1A, MCL1, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
4.24245 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
AKR1C3, BCL2, CYP1B1, EGFR, HIF1A, INSR, PTGS2, SMAD3, TRPV1, XDH |
4.24147 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
ADRB1, APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
4.23796 |
|
[BP] GO:0040008 |
regulation of growth
|
ADRB1, ALOX12, APP, AR, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, ESR2, HIF1A, HSPA1A, INSR, PIK3CA, PIM1, PTPRS, SMAD3, TNKS2 |
4.21064 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, GBA, GPER1, MMP12, PPARA, SMAD3, TEK |
4.19945 |
|
[BP] GO:0002031 |
None
|
DRD2, DRD3, HTR1B, HTR2B |
4.16405 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, AKR1C3, CYP19A1, GLO1, HMGCR, HSD17B3 |
4.15696 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HIF1A, HTR2B, TERT |
4.15332 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
AKR1C3, ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HIF1A, HSD17B2, HSD17B3, INSR, KIT, PGR, PTGS2, SRC |
4.12158 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
ALOX12, CYP1B1, F3, GPER1, HIF1A, KDR, KIT, PTGS2, TEK, TERT |
4.11487 |
|
[BP] GO:1900543 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PPARA |
4.07753 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
ALOX12, BCL2, CYP1A1, CYP1A2, CYP1B1, DRD5, EGFR, MAOB |
4.07162 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, GPER1, INSR, MIF, SRC, TERT |
4.05764 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, TRPV1 |
4.05383 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, HCAR2, HMGCR, MCL1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.04788 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, DRD2, DRD3, DRD5, DUSP3, ESR1, FABP4, GBA, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
4.04421 |
|
[BP] GO:0045980 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PPARA |
4.04268 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, GBA, HSD11B2, MAOB, NR3C1, PTGS2 |
4.03791 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, AKR1C3, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, FUCA1, GBA, GBA2 |
4.03566 |
|
[BP] GO:0001975 |
None
|
CNR2, DRD1, DRD2, DRD3, DRD5 |
4.03566 |
|
[BP] GO:0006693 |
None
|
AKR1C3, CES2, MIF, PTGS1, PTGS2 |
4.03566 |
|
[BP] GO:0006692 |
None
|
AKR1C3, CES2, MIF, PTGS1, PTGS2 |
4.03566 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
AKR1C3, ALOX12, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DAO, FABP3, GBA2, GLO1, HIF1A, MIF, PIM1, PPARA, PTGS1, PTGS2, TBXAS1, TYR |
4.02693 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, HCAR2, HMGCR, MCL1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.99862 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, DRD3, GBA, GPER1, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.97979 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
3.97947 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CACNA1C, CNR1, CSNK2A1, DRD2, DRD3, DYRK2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.97947 |
|
[BP] GO:0071383 |
None
|
AKR1C3, AR, EGFR, FLT3, GPER1, NR3C1, SRC |
3.97458 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, AKR1C3, HIF1A, MMP1, MMP12, MMP2, MMP9, TRPV1 |
3.96458 |
|
[BP] GO:0030815 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E |
3.95096 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR, FDPS |
3.93586 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, SRC, TRPV1 |
3.93104 |
|
[BP] GO:0044283 |
None
|
AKR1B1, AKR1C3, ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, FDPS, GBA, HMGCR, HSD17B3, MIF, PTGS1, PTGS2 |
3.9257 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GAA, GRM1, GRM5, GRM8, HIF1A, HMGCR, HTR2A, INSR, KIT, PTGS2, TRPV1, TYR |
3.91748 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.91579 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AKR1C3, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.91064 |
|
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, ERBB2, F3, HIF1A, HTR2B, KDR, MMP12, PGR, SMAD3, TEK, XDH |
3.90945 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CACNA1C, CNR1, DRD2, DRD3, DYRK2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC |
3.90945 |
|
[BP] GO:0051952 |
None
|
ADORA1, CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A |
3.90747 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, HTR2A, MIF, POLB, PTGS2, TERT |
3.90578 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, AKR1C3, ALPL, APP, AR, AXL, BCL2, CBR1, CDC25B, CDK6, CYP1A1, DRD1, DRD2, DYRK3, EGFR, ERBB2, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HIF1A, HMGCR, HTR2B, KDR, KIT, MCL1, MET, MIF, MMP2, MMP9, PGR, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
3.89784 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD2, DRD3, HTR1B, HTR2A |
3.88922 |
|
[BP] GO:0030800 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E |
3.8591 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, AKR1C3, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, DRD5, EGFR, ESR1, ESRRB, HIF1A, HSD11B2, HSD17B2, HSD17B3, INSR, KIT, MMP2, MMP9, PGR, PTGS2, SRC, TOP2A |
3.85518 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, GPER1, NR3C1, PGR, SRC |
3.83825 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, HMGCR, KIT, PTGS2, TYR |
3.82151 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, CHRM2, DRD2, EGFR, GAA, HTR2A, PDE5A, PTGS2, SLC1A1 |
3.82151 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX12, ALOX15, MIF, PTGS1, PTGS2 |
3.81702 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ERBB2, ESR1, ESRRA, GPER1, HCAR2, HIF1A, HSPA1A, KIT, MIF, MMP12, MMP2, PDE5A, PIK3CA, PIK3CB, PTPN1, PTPRS, SMAD3, SRC |
3.80208 |
|
[BP] GO:0051282 |
None
|
CACNA1C, DRD1, DRD2, GPER1, HTR2A, HTR2B, HTR2C, TRPV1 |
3.77819 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, GBA, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KDR, MCL1, MET, PIK3CA, PIK3CB, PPARA, PTPN1, SMAD3 |
3.76637 |
|
[BP] GO:0010676 |
None
|
DYRK2, ESRRB, GPER1, INSR, PPARA, SRC |
3.76637 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
3.74588 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR1B, HTR2A |
3.74588 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AKR1C3, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PTGS1, PTGS2, SRC |
3.74585 |
|
[BP] GO:1900544 |
None
|
ADRB1, DRD1, DRD5, ESRRB, GPER1, HIF1A, HTR2A, INSR |
3.73112 |
|
[BP] GO:0045981 |
None
|
ADRB1, DRD1, DRD5, ESRRB, GPER1, HIF1A, HTR2A, INSR |
3.73112 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, GBA, GPER1, PPARA, SMAD3, TEK |
3.73112 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CBR1, CDC25B, CDK6, CES2, CHRM2, CLK1, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
3.72188 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CACNA1C, CNR1, DRD2, DRD3, DYRK2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, PTGS2, PTPN1, SMAD3, SRC |
3.70641 |
|
[BP] GO:0042220 |
None
|
CNR1, DRD2, DRD3, DRD5, HTR1B |
3.68206 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, GBA, GPER1, HSPA1A, MMP12, MMP2, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK |
3.66712 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
CACNA1C, DRD1, DRD2, ESR1, GPER1, GPR35, GRM1, HTR2A, HTR2B, HTR2C, TRPV1 |
3.63643 |
|
[BP] GO:0032768 |
None
|
CNR1, CNR2, EGFR, HIF1A, HTR2B, TERT |
3.63629 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MCL1, MIF, MMP9, PTGS2, PTPN1, SRC |
3.6324 |
|
[BP] GO:0061370 |
testosterone biosynthetic process
|
AKR1C3, CYP19A1, HSD17B3 |
3.6316 |
|
[BP] GO:0071502 |
None
|
HTR1B, HTR2B, TRPV1 |
3.6316 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.6316 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.6316 |
|
[BP] GO:0042596 |
None
|
ADRB1, BCL2, DRD1, HTR1A, HTR2C |
3.62274 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GBA, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.60601 |
|
[BP] GO:0046686 |
response to cadmium ion
|
AKR1C3, CYP1A2, EGFR, KIT, MMP9, TERT |
3.59958 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, HCAR2, HMGCR, MCL1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.59901 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
3.57322 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
3.55988 |
|
[BP] GO:0010907 |
None
|
DYRK2, ESRRB, INSR, PPARA, SRC |
3.55988 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, SRC |
3.53668 |
|
[BP] GO:0051341 |
None
|
CNR1, CNR2, DRD5, EGFR, HIF1A, HTR2B, TERT |
3.52364 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, MCL1, PIK3CA, SRC |
3.52265 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.52265 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
3.52265 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.52265 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GBA, GPER1, HIF1A, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
3.50109 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, GPER1, HIF1A, HMGCR, HTR2A, HTR2C, INSR, KDR, KIT, PDE5A, PIM1, PTGS2, SMAD3, SRC, TEK, TERT |
3.49917 |
|
[BP] GO:2001023 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A, MET |
3.49842 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, HASPIN, TERT, TNKS, TNKS2 |
3.47987 |
|
[BP] GO:0050708 |
None
|
ACHE, CACNA1C, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, SRC |
3.47136 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
AKR1C3, EGFR, INSR, PTGS2, SMAD3, TRPV1, XDH |
3.46889 |
|
[BP] GO:0046890 |
None
|
AKR1C3, FABP3, FDPS, GPER1, HMGCR, HTR2A, HTR2B, HTR2C, PTGS2 |
3.46213 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.44431 |
|
[BP] GO:0019933 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, HTR5A |
3.44067 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MCL1, MET, PIK3CA, PPARA, SMAD3 |
3.42545 |
|
[BP] GO:0003012 |
None
|
ADORA1, DRD1, DRD2, GAA, HTR1D, HTR2A, HTR2B, HTR7, PDE5A, PIK3CA, TRPV1 |
3.41081 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.40306 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRB1, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FDPS, GBA, GLO1, GPER1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, POLA1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.38956 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
AKR1C3, ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, GBA, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
3.38864 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
3.3885 |
|
[BP] GO:0032229 |
None
|
ADORA1, CNR2, HTR1B |
3.36564 |
|
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX12, ALOX15, ALOX5 |
3.36564 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD2, DRD3, DYRK2, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, MAOB, MMP9, PTGS2 |
3.36014 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, GPER1, KIT, MIF, PIK3CA, PIK3CB, POLB, PTGS1, PTGS2, TRPV1 |
3.36014 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
3.33526 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
DYRK2, ESRRB, GPER1, HIF1A, HTR2A, INSR, PPARA, RORC, SRC |
3.33526 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AKR1C3, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.33526 |
|
[BP] GO:0048608 |
reproductive structure development
|
AKR1C3, AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, HSD17B3, INSR, KIT, SRC |
3.33243 |
|
[BP] GO:0045821 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.33045 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR1D, HTR2B |
3.33045 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, ERBB2, F3, HIF1A, HTR2B, KDR, MMP12, TEK |
3.31964 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, GPER1, HIF1A, HSPA1A, MCL1, MIF, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.31423 |
|
[BP] GO:0060402 |
None
|
CACNA1C, DRD2, HTR2A, HTR2B, HTR2C, TRPV1 |
3.30066 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
ERBB2, HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.30066 |
|
[BP] GO:0014075 |
None
|
CNR2, DRD1, DRD2, DRD3, DRD5 |
3.28828 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, GBA, MAOB, NR3C1, SRC |
3.26647 |
|
[BP] GO:0051197 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.23849 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
ALOX12, CYP1B1, ERBB2, F3, GPER1, HIF1A, KDR, KIT, PTGS2, TEK, TERT, XDH |
3.23849 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, GBA, GPER1, PPARA, PTGS2, SMAD3, TEK |
3.23819 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
GPER1, HTR1B, MMP2, MMP9, TERT |
3.23577 |
|
[BP] GO:0019935 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1, HTR5A |
3.20033 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PTGS2, SMAD3, SRC |
3.18942 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, HTR2A, KIT, MIF, PTPN1, SRC |
3.16907 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3, HTR2A |
3.15294 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.15294 |
|
[BP] GO:0014062 |
None
|
HTR1A, HTR1B, MAOB |
3.15294 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.15294 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.15294 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.13615 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.13615 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.12557 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, SRC |
3.11314 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, TERT |
3.09039 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TERT, TNKS, TOP2A |
3.08928 |
|
[BP] GO:0031667 |
response to nutrient levels
|
AKR1C3, ALPL, BCL2, CNR1, CYP1A1, EGFR, GBA, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
3.05918 |
|
[BP] GO:0007189 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GPER1 |
3.02724 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CACNA1C, CSNK2A1, DRD1, DRD2, DRD3, DYRK2, EGFR, ERBB2, GPER1, GRIK5, HIF1A, HMGCR, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.01775 |
|
[BP] GO:0007584 |
response to nutrient
|
AKR1C3, ALPL, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, TRPV1, TYR |
3.00934 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
AKR1C3, ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.00934 |
|
[BP] GO:0030818 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B |
2.99672 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
2.99672 |
|
[BP] GO:0051194 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
2.99672 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AKR1C3, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.99672 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
2.97529 |
|
[BP] GO:0009266 |
None
|
ADORA1, ADRB1, HSPA1A, HTR1B, HTR2A, HTR2B, PTGS2, TRPV1 |
2.9751 |
|
[BP] GO:0044597 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.9751 |
|
[BP] GO:0044598 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.9751 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
2.9751 |
|
[BP] GO:0016139 |
None
|
FUCA1, GBA, GBA2 |
2.9751 |
|
[BP] GO:0050665 |
hydrogen peroxide biosynthetic process
|
CYP1A1, CYP1A2, MAOB |
2.9751 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
2.9751 |
|
[BP] GO:0030638 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.9751 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GPER1, GRM3, GRM8, HMGCR, HSPA1A, HTR1B, HTR1E, IGF1R, MIF, MMP12, MMP9, NR3C1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.97238 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, TRPV1 |
2.96098 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, TRPV1 |
2.96098 |
|
[BP] GO:0097366 |
None
|
CNR2, DRD1, DRD2, DRD3, DRD5 |
2.96098 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, GBA, GPER1, GRIK5, HIF1A, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PIK3CB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.95899 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, DNMT1, DRD2, DRD3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
2.95195 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, DRD2, EGFR, ERBB2, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, PTGS2, SMAD3, SRC |
2.93316 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, MCL1, PIK3CA, SRC |
2.93285 |
|
[BP] GO:0030803 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B |
2.91927 |
|
[BP] GO:0060401 |
None
|
CACNA1C, DRD2, HTR2A, HTR2B, HTR2C, TRPV1 |
2.91746 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
ALOX12, CYP1B1, F3, HIF1A, KDR, PTGS2, TEK, TERT |
2.90921 |
|
[BP] GO:0048167 |
None
|
ADORA1, APP, DRD1, DRD2, DRD5, GRM5, KIT, PTGS2 |
2.90921 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, HMGCR, KIT, POLB, PTGS2, TYR |
2.90236 |
|
[BP] GO:0042060 |
None
|
ALOX15, DRD5, EGFR, ERBB2, PPARA, SMAD3 |
2.88969 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
2.88969 |
|
[BP] GO:0050433 |
None
|
CNR1, DRD2, DRD3, HTR1B, HTR2A |
2.88015 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
2.88015 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GBA, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.8788 |
|
[BP] GO:0042737 |
drug catabolic process
|
ACHE, CYP1A2, CYP2A6, CYP3A4, DAO, MAOA, MAOB |
2.8788 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.8788 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
2.86791 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MAOB |
2.86791 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CLK1, CSNK2A1, DYRK1A, HASPIN, TNKS |
2.86387 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
2.83958 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CLK1, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GBA, GLO1, GPER1, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.8331 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
ADRB1, APP, AR, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, PTPRS, TNKS2 |
2.83302 |
|
[BP] GO:0030647 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.82656 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.82 |
|
[BP] GO:1901570 |
None
|
ALOX12, ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
2.80739 |
|
[BP] GO:1900372 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B |
2.80538 |
|
[BP] GO:2000351 |
None
|
AKR1C3, GPER1, KDR, TEK, TERT |
2.80538 |
|
[BP] GO:0030809 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B |
2.80538 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
2.80538 |
|
[BP] GO:0048169 |
None
|
APP, DRD2, GRM5, KIT |
2.80538 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, BCL2, CDK6, CYP1B1, DRD2, ERBB2, FABP3, GPER1, HSPA1A, PDE5A, PTGS2, SMAD3, TERT, XDH |
2.78432 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, HIF1A, MIF, PIK3CB |
2.75329 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, GRM5, MIF |
2.75329 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, GPER1, HSPA1A, INSR, MIF, PIM1, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
2.74433 |
|
[BP] GO:0046466 |
None
|
CYP1B1, FUCA1, GBA, GBA2 |
2.74141 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
2.74141 |
|
[BP] GO:0010675 |
None
|
DYRK2, ESRRB, GPER1, INSR, PPARA, RORC, SRC |
2.73226 |
|
[BP] GO:0043467 |
regulation of generation of precursor metabolites and energy
|
DYRK2, ESRRB, HIF1A, HTR2A, INSR, PIK3CA, PPARA |
2.71116 |
|
[BP] GO:0006936 |
None
|
DRD1, DRD2, GAA, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
2.71116 |
|
[BP] GO:0006811 |
None
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, FABP3, GRIA2, GRIA4, GRIK5, HTR2A, HTR2B, HTR2C, PPARA, SLC1A1, TRPV1 |
2.6952 |
|
[BP] GO:0007191 |
None
|
DRD1, DRD3, DRD5 |
2.69176 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.69176 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.69176 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, HIF1A, KDR, KIT, POLB, TEK, TYR |
2.69098 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, GPER1, HSPA1A, INSR, MIF, TERT, TNKS |
2.67755 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CLK1, CSNK2A1, DYRK1A, HASPIN, TNKS |
2.67755 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, GPER1, HTR5A, PTGS2 |
2.67317 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.66597 |
|
[BP] GO:0098900 |
None
|
CACNA1C, CNR1, CNR2, GBA, GPR35 |
2.66597 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PTGS2, SRC, TEK |
2.66597 |
|
[BP] GO:0046960 |
None
|
DRD1, DRD5 |
2.66597 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.66597 |
|
[BP] GO:0016488 |
None
|
AKR1B10, AKR1C3 |
2.66597 |
|
[BP] GO:0016487 |
None
|
AKR1B10, AKR1C3 |
2.66597 |
|
[BP] GO:0006680 |
None
|
GBA, GBA2 |
2.66597 |
|
[BP] GO:0016107 |
None
|
AKR1B10, AKR1C3 |
2.66597 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.66597 |
|
[BP] GO:0006714 |
None
|
AKR1B10, AKR1C3 |
2.66597 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.66597 |
|
[BP] GO:2001301 |
lipoxin biosynthetic process
|
ALOX12, ALOX15 |
2.66597 |
|
[BP] GO:2001302 |
lipoxin A4 metabolic process
|
ALOX12, ALOX15 |
2.66597 |
|
[BP] GO:2001303 |
lipoxin A4 biosynthetic process
|
ALOX12, ALOX15 |
2.66597 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
AKR1C3, HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.66583 |
|
[BP] GO:0050866 |
negative regulation of cell activation
|
ALOX12, AXL, CNR1, CNR2, DUSP3, ERBB2, GPER1, PDE5A |
2.65617 |
|
[BP] GO:0051482 |
None
|
DRD1, GPR35, GRM1, HTR2C |
2.63989 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.63989 |
|
[BP] GO:0008209 |
androgen metabolic process
|
CYP19A1, CYP3A4, ESR1, HSD17B3 |
2.63989 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
ADRB1, BCL2, DRD1, HTR1A, HTR2C |
2.63591 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
AKR1C3, ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.62456 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, ADRB1, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1B, DYRK2, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPER1, GRM3, GRM5, GRM8, HIF1A, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KIT, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, POLA1, PPARA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.61868 |
|
[BP] GO:0060359 |
None
|
CNR1, DRD1, DRD2, DRD3, DRD5, HTR1B |
2.61593 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, GRM5, HTR2A, KIT, MIF, PTPN1, SRC |
2.6096 |
|
[BP] GO:0044242 |
None
|
AKR1B10, AKR1C3, CYP1B1, FABP3, FABP4, FUCA1, GBA, GBA2 |
2.6096 |
|
[BP] GO:0031623 |
None
|
ACHE, DRD2, DRD3, HTR1B, HTR2B |
2.60136 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUCA1, FUT7, GAA, HSPA1A, KIT, MGAM, MIF, MMP9, PIK3CA, PIK3CB, RORC, SMAD3, SRC, TRPV1 |
2.59715 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, ADRB1, APEX1, APP, AR, AURKB, CA9, CLK1, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GPER1, GRM3, GRM8, HIF1A, HSPA1A, HTR1B, HTR1E, HTR2A, IGF1R, INSR, KIT, MET, MMP12, NR3C1, NR3C2, PDE5A, PGR, PIK3CA, PIM1, POLA1, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.59444 |
|
[BP] GO:0045936 |
None
|
DRD2, DRD3, DUSP3, FABP4, GBA, GPER1, GRM3, GRM8, HMGCR, HTR1B, HTR1E, IGF1R, PPARA, PTPN1, XDH |
2.59057 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, GPER1, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK, TRPV1 |
2.58987 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.58925 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.58925 |
|
[BP] GO:0051385 |
None
|
GPER1, HTR1B, MAOB, SRC |
2.58825 |
|
[BP] GO:0010563 |
None
|
DRD2, DRD3, DUSP3, FABP4, GBA, GPER1, GRM3, GRM8, HMGCR, HTR1B, HTR1E, IGF1R, PPARA, PTPN1, XDH |
2.58637 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX12, ALOX15, BCL2, CDK6, CYP1B1, DUSP3, ERBB2, KDR, NUAK1, PDE5A, PIK3CA, PIK3CB, PPARA, SMAD3, SRC, TEK |
2.54603 |
|
[BP] GO:0043279 |
None
|
CNR1, DRD2, DRD3, DRD5, HTR1B, TRPV1 |
2.54523 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.54448 |
|
[BP] GO:0097553 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, TRPV1 |
2.53868 |
|
[BP] GO:0072347 |
None
|
CNR1, DRD2, DRD3, DRD5, HTR1B |
2.53868 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.53868 |
|
[BP] GO:0035265 |
organ growth
|
AR, BCL2, CYP19A1, ESR1 |
2.53868 |
|
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.53868 |
|
[BP] GO:1901661 |
None
|
AKR1B1, AKR1B10, AKR1C3, HMGCR |
2.53868 |
|
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.53868 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.53868 |
|
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, EGFR, MAOB |
2.53868 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, DRD3, GAA, GRM1, GRM5, HTR2C |
2.52265 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, ERBB2, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
2.51912 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
AKR1C3, APEX1, AR, EGFR, ESR1, FLT3, GPER1, INSR, KIT, NR3C1, SRC |
2.5167 |
|
[BP] GO:0071276 |
cellular response to cadmium ion
|
AKR1C3, CYP1A2, EGFR, MMP9 |
2.48591 |
|
[BP] GO:0010039 |
response to iron ion
|
BCL2, CYP1A1, DRD2, HIF1A |
2.48591 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
ALOX12, APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, ERBB2, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, SRC, TEK, TUBB3 |
2.48509 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.4839 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.4839 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
2.47672 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, DYRK1A, EGFR, HTR7, PPARA, RORC |
2.46734 |
|
[BP] GO:0071384 |
None
|
AKR1C3, EGFR, FLT3, GPER1, NR3C1 |
2.44298 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.43573 |
|
[BP] GO:0010906 |
None
|
DYRK2, ESRRB, INSR, PPARA, RORC, SRC |
2.4336 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, AKR1C3, BCL2, DRD2, HSD11B2 |
2.4336 |
|
[BP] GO:0008016 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, CHRM2, DRD2, GAA, PDE5A, SLC1A1 |
2.43005 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, AKR1C3, ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, GBA, HMGCR, HSD11B2, HTR2A, KIT, MAOB, MMP12, PTGS2, SMAD3, SRC, TRPV1, TYR |
2.42299 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, FLT3, GPER1, KDR, KIT, TEK |
2.4125 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AKR1C3, AOX1, AURKB, BACE1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, HSPA1A, MAOA, MAOB, MGAM, PDE5A, XDH |
2.40645 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, DRD1, DRD5, EGFR, ESR1, KIT, PGR, PTGS2, SRC |
2.40592 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
2.39292 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, RORC, TOP2A |
2.39292 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.39292 |
|
[BP] GO:1902893 |
None
|
HIF1A, PPARA, SMAD3, TERT |
2.39292 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, GPER1, HCAR2, HIF1A, HTR2B, MIF, MMP12, SRC |
2.39292 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AKR1C3, AR, AXL, CDK6, EGFR, ESR1, FLT3, GPER1, NR3C1, RORC, SRC |
2.39292 |
|
[BP] GO:0010628 |
positive regulation of gene expression
|
APP, AR, DNMT1, DRD1, DRD2, DRD3, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, HSPA1A, INSR, KIT, MET, MMP12, NR3C1, PGR, PIK3CB, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.39075 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
2.39075 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.39075 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.39075 |
|
[BP] GO:0001516 |
None
|
MIF, PTGS1, PTGS2 |
2.39075 |
|
[BP] GO:0060158 |
None
|
DRD1, DRD2, DRD5 |
2.39075 |
|
[BP] GO:0046457 |
None
|
MIF, PTGS1, PTGS2 |
2.39075 |
|
[BP] GO:0045893 |
None
|
APP, AR, DRD2, DRD3, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.38876 |
|
[BP] GO:1903508 |
None
|
APP, AR, DRD2, DRD3, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.38876 |
|
[BP] GO:1902680 |
None
|
APP, AR, DRD2, DRD3, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.3851 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.37782 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.37782 |
|
[BP] GO:1901184 |
None
|
ADORA1, APP, EGFR, ERBB2, GPER1, MMP9 |
2.37782 |
|
[BP] GO:0046854 |
phosphatidylinositol phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.37782 |
|
[BP] GO:0030258 |
lipid modification
|
ALOX12, CYP1A1, CYP3A4, EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.36551 |
|
[BP] GO:1903580 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
2.3524 |
|
[BP] GO:2001240 |
None
|
BCL2, HSPA1A, MCL1, TERT |
2.3524 |
|
[BP] GO:1901099 |
None
|
BCL2, HSPA1A, MCL1, TERT |
2.3524 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.34117 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.33582 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.33582 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.33582 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.33582 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PTGS2 |
2.33582 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM2, GPER1, KIT, PTGS2 |
2.30442 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, GBA, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KDR, MCL1, MET, PIK3CA, PIK3CB, PPARA, PTPN1 |
2.3031 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.3031 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.3031 |
|
[BP] GO:0043518 |
None
|
DYRK1A, DYRK3, MIF |
2.3031 |
|
[BP] GO:0019377 |
None
|
FUCA1, GBA, GBA2 |
2.3031 |
|
[BP] GO:0051254 |
None
|
APP, AR, DRD2, DRD3, DYRK1B, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HIF1A, HSPA1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.30041 |
|
[BP] GO:2001237 |
negative regulation of extrinsic apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MCL1, SRC, TERT |
2.29467 |
|
[BP] GO:0051241 |
negative regulation of multicellular organismal process
|
ADORA1, ADRB1, ALOX12, APP, AXL, BCL2, CDK6, DRD2, DRD3, EGFR, ERBB2, GBA, GPR35, HIF1A, PDE5A, PTGS2, PTPRS, SMAD3, TEK, TERT, XDH |
2.28682 |
|
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
FLT3, GPER1, KDR, KIT, TEK |
2.28012 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.26984 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.26984 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.26984 |
|
[BP] GO:0000023 |
None
|
GAA, MGAM |
2.26984 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.26984 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.26984 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.26984 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.26984 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.26984 |
|
[BP] GO:0016095 |
None
|
AKR1B10, AKR1C3 |
2.26984 |
|
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, PTGS2 |
2.26414 |
|
[BP] GO:0006110 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA |
2.26259 |
|
[BP] GO:0034762 |
None
|
ABCB1, APP, BCL2, CA2, CACNA1C, DRD1, DRD2, DRD3, GPER1, GPR35, GRM5, MMP9 |
2.23979 |
|
[BP] GO:0002695 |
negative regulation of leukocyte activation
|
AXL, CNR1, CNR2, DUSP3, ERBB2, GPER1, PDE5A |
2.23603 |
|
[BP] GO:0007190 |
None
|
ADORA3, ADRB1, DRD1, DRD5 |
2.23565 |
|
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.23565 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.23565 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, GRM1, INSR, KIT, PIK3CA, PIK3CB, PTPN1, SRC |
2.23252 |
|
[BP] GO:0045725 |
None
|
DYRK2, ESRRB, INSR |
2.23252 |
|
[BP] GO:0050965 |
None
|
ADORA1, HTR2A, TRPV1 |
2.23252 |
|
[BP] GO:0050961 |
None
|
ADORA1, HTR2A, TRPV1 |
2.23252 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.23252 |
|
[BP] GO:0090276 |
None
|
CACNA1C, CNR1, DRD2, EGFR, GPER1, HIF1A, HMGCR, HTR2C |
2.22405 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, AKR1C3, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, DYRK2, EGFR, GBA, HIF1A, HSPA1A, MCL1, MIF, MMP9, NUAK1, POLA1, POLB, PTGS2, PTPN1, SRC, TERT, TOP2A, TRPV1 |
2.22372 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.21135 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
2.20817 |
|
[BP] GO:0008406 |
gonad development
|
AKR1C3, BCL2, CYP19A1, ESR1, INSR, KIT |
2.20817 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AKR1C3, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, DAO, FABP3, FABP4, FUCA1, GAA, GBA, GBA2, HSPA1A, MAOA, MAOB, MGAM, PDE5A, PIK3CB, SRC, XDH |
2.19734 |
|
[BP] GO:0048806 |
genitalia development
|
AXL, CYP19A1, ESR1, HSD17B3 |
2.19734 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SRC, TERT |
2.18584 |
|
[BP] GO:0031644 |
None
|
ADORA1, GBA, GPR35, GRM1, HTR2C |
2.18584 |
|
[BP] GO:1903524 |
None
|
ADRB1, EGFR, HTR2A, PTGS2, SLC1A1 |
2.18584 |
|
[BP] GO:2001236 |
regulation of extrinsic apoptotic signaling pathway
|
AR, BCL2, GPER1, HSPA1A, MCL1, SRC, TERT |
2.17762 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, GPER1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.17297 |
|
[BP] GO:0019637 |
organophosphate metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, ERBB2, FDPS, HMGCR, HSPA1A, HTR2B, HTR2C, KIT, MET, PDE5A, PIK3CA, PIK3CB, PTGS2, XDH |
2.16566 |
|
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CDK6, CNR1, DRD2, DRD3, EGFR, ERBB2, ESRRA, ESRRB, GPER1, HIF1A, HTR2A, HTR2C, KDR, KIT, PDE5A, PPARA, PTGS2, PTPRS, RORC, SMAD3, TERT, TRPV1, XDH |
2.16265 |
|
[BP] GO:0010507 |
negative regulation of autophagy
|
BCL2, HTR2B, MCL1, MET, PIK3CA |
2.15966 |
|
[BP] GO:0003073 |
None
|
AR, DRD3, DRD5, HSD11B2 |
2.15856 |
|
[BP] GO:0038128 |
None
|
EGFR, ERBB2, PIK3CA, SRC |
2.15856 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, AKR1C3, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
2.15821 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.15821 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.15821 |
|
[BP] GO:0070875 |
None
|
DYRK2, ESRRB, INSR |
2.15821 |
|
[BP] GO:0048546 |
None
|
BCL2, EGFR, HIF1A |
2.15821 |
|
[BP] GO:0046834 |
lipid phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.15405 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GPER1, GRM5, IGF1R, INSR, SRC |
2.15174 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.1372 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF, NISCH |
2.13465 |
|
[BP] GO:1901361 |
None
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DAO, HSPA1A, MAOA, MAOB, PDE5A, XDH |
2.12825 |
|
[BP] GO:0006937 |
None
|
ADORA1, CACNA1C, CHRM2, GPER1, KIT, PDE5A, PTGS2 |
2.08745 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, F3, GPER1, HIF1A, HMGCR, INSR, KDR, KIT, PIM1, PTGS2, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
2.08696 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.08601 |
|
[BP] GO:0009268 |
None
|
CA2, GBA, SRC, TRPV1 |
2.08402 |
|
[BP] GO:0033574 |
response to testosterone
|
AR, CA9, CSNK2A1, GBA |
2.08402 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.08402 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, MAOB, NQO2, XDH |
2.07544 |
|
[BP] GO:0051093 |
None
|
ADRB1, APP, BCL2, CDK6, DRD3, EGFR, ERBB2, ESRRB, GPER1, HIF1A, MIF, PPARA, PTPRS, SMAD3, TEK, TERT, TRPV1, XDH |
2.07486 |
|
[BP] GO:0043470 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA |
2.06241 |
|
[BP] GO:0045471 |
None
|
CNR1, DRD3, HMGCR, HTR1B, MAOB, POLB |
2.06042 |
|
[BP] GO:1904035 |
regulation of epithelial cell apoptotic process
|
AKR1C3, GPER1, KDR, TEK, TERT |
2.03738 |
|
[BP] GO:0022602 |
ovulation cycle process
|
BCL2, ESR1, KIT, PGR, SRC |
2.03738 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, TERT |
2.03738 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, CLK1, DRD1, DYRK1A, SRC, TNKS |
2.03144 |
|
[BP] GO:0006650 |
glycerophospholipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.02503 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, DRD1, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, HASPIN, HIF1A, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.02411 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, DRD1, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, HASPIN, HIF1A, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.02411 |
|
[BP] GO:0006066 |
None
|
AKR1B1, AKR1B10, AKR1C3, APP, CYP1B1, CYP3A4, FDPS, GBA, HMGCR |
2.0185 |
|
[BP] GO:0051000 |
None
|
HIF1A, HTR2B, TERT |
2.0185 |
|
[BP] GO:0001961 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.0185 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.0185 |
|
[BP] GO:0098908 |
None
|
GBA, GPR35 |
2.0185 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.0185 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.0185 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.0185 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.0185 |
|
[BP] GO:0014063 |
None
|
HTR1B, MAOB |
2.0185 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.0185 |
|
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.0185 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, MAOB, PTGS2, SRC |
2.01704 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CLK1, CSNK2A1, DNMT1, DRD1, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, HASPIN, HIF1A, HTR2B, IGF1R, INSR, KDR, KIT, MET, NR3C1, NUAK1, PIK3CA, PIM1, POLB, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.01533 |
|
[BP] GO:1901214 |
regulation of neuron death
|
AXL, BCL2, GBA, GRIK5, HIF1A, MCL1, PIK3CA, PPARA, TERT |
2.00668 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRB1, APP, AXL, BACE1, CA4, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, F10, F3, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTPRS, SLC1A1, TEK, TRPV1 |
11.0955 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ABCG2, ADORA1, ADORA3, ADRB1, ALOX15, APP, AXL, BACE1, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, F10, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MGAM, PTGS2, PTPRS, SLC1A1, SRC, TEK, TRPV1 |
10.5856 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, ALOX12, ALOX15, ALPL, APP, AR, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F10, F3, FLT3, GAA, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MGAM, MMP2, NISCH, PIK3CA, PIK3CB, PIM1, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
10.0338 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRB1, APP, AXL, BACE1, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTPRS, SLC1A1, TEK, TRPV1 |
9.8128 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, ALOX12, ALOX15, ALOX5, ALPL, APP, AR, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, MMP2, NISCH, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
8.97864 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ABCG2, ADORA1, CA2, CA4, CA9, CHRM2, CNR1, DRD1, DRD2, DRD5, EGFR, ERBB2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, INSR, MET, MGAM, PTGS2, SLC1A1, SRC, TEK, TRPV1 |
7.69169 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, ALOX15, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GBA2, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, NR3C2, PIK3CA, PIK3CB, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SRC, TBXAS1, TEK, TRPV1, TYR |
6.54355 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CACNA1C, CBR1, CDC25B, CDK6, CES2, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DRD1, DRD2, DRD3, DUSP3, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, F10, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GRIA2, GRIA4, GRIK5, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR2A, HTR4, HTR5A, INSR, KDR, KIT, MAOA, MAOB, MCL1, MGAM, MIF, MMP2, MMP9, NISCH, NQO2, NR3C1, NR3C2, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.79364 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ABCG2, ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CBR1, CDK6, CES2, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GRIA4, GRIK5, GRM1, GRM5, HASPIN, HIF1A, HMGCR, HSD17B3, HSPA1A, HTR2A, HTR4, HTR5A, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MGAM, MIF, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SHBG, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
5.2175 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ABCG2, ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CACNA1C, CBR1, CDK6, CES2, CLK1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HASPIN, HIF1A, HMGCR, HSD17B3, HSPA1A, HTR2A, HTR4, HTR5A, HTR6, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MGAM, MIF, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SHBG, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
5.13263 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, PTPRS, SRC, TEK, TUBB3 |
5.09002 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD5, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, PTPRS, SRC, TEK, TUBB3 |
5.09002 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, BACE1, CA2, CHRM2, CNR1, CNR2, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, PTGS2, PTPRS, SRC, TUBB3 |
4.69288 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA7, CA9, CACNA1C, CBR1, CDC25B, CDK6, CES2, CHRM2, CLK1, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, MIF, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.54151 |
|
[CC] GO:0042734 |
None
|
CNR1, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
4.44858 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, EGFR, F10, FLT3, GBA2, GPER1, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, NR3C2, PTGS1, PTGS2, PTPN1, TBXAS1 |
4.22767 |
|
[CC] GO:0031224 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, ALPL, APP, AXL, BACE1, CA12, CA14, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CYP3A4, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GBA2, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, PTPRS, SLC1A1, TBXAS1, TEK, TRPV1, TYR |
3.74988 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DRD1, EGFR, GBA2, GPER1, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, NR3C2, PTGS1, PTGS2, TBXAS1 |
3.74115 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, BACE1, CA2, CACNA1C, CHRM2, CNR1, CNR2, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HTR2A, HTR2B, HTR5A, INSR, PTGS1, PTGS2, PTPRS, SRC, TRPV1, TUBB3 |
3.62655 |
|
[CC] GO:0043235 |
receptor complex
|
ABCG2, APP, EGFR, ERBB2, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, NR3C2, SMAD3 |
3.34242 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CACNA1C, CHRM2, CNR1, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PTPRS, SRC, TRPV1 |
3.33526 |
|
[CC] GO:0016021 |
None
|
ABCB1, ABCG2, ADORA1, ADORA3, ADRB1, ALPL, APP, AXL, BACE1, CA12, CA14, CA9, CACNA1C, CHRM2, CNR1, CNR2, CYP3A4, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F3, FLT3, FUT7, GBA2, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, PTPRS, SLC1A1, TBXAS1, TEK, TRPV1, TYR |
3.29214 |
|
[CC] GO:0097060 |
None
|
CHRM2, CNR1, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, TRPV1 |
3.11091 |
|
[CC] GO:0014069 |
None
|
ADORA1, CACNA1C, DRD2, GPER1, GRIK5, GRM1, GRM3, GRM5, SRC |
2.94125 |
|
[CC] GO:0099572 |
None
|
ADORA1, CACNA1C, DRD2, GPER1, GRIK5, GRM1, GRM3, GRM5, SRC |
2.94125 |
|
[CC] GO:0031090 |
None
|
ABCG2, ALOX5, APP, BACE1, BCL2, CA4, CHRM2, CNR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DRD1, DRD2, DRD5, EGFR, ERBB2, FUT7, GAA, GBA, GBA2, GPER1, GRIA2, GRIA4, HMGCR, INSR, MAOA, MAOB, MCL1, MGAM, PGR, PTGS1, PTGS2, SMAD3, SRC, TNKS, TNKS2, TYR |
2.90554 |
|
[CC] GO:0030424 |
None
|
APP, BACE1, CA2, CNR1, DRD2, GPER1, GRM3, HTR2A, PTPRS, TUBB3 |
2.82656 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM2, CNR1, DRD1, DRD2, DRD5, GPER1, GRIA2, GRIA4, GRIK5, GRM3, HIF1A, HTR2A, INSR, PTGS1, SRC, TRPV1 |
2.50981 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM2, CNR1, DRD1, DRD2, DRD5, GPER1, GRIA2, GRIA4, GRIK5, GRM3, HIF1A, HTR2A, INSR, PTGS1, SRC, TRPV1 |
2.50981 |
|
[CC] GO:0045121 |
membrane raft
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.42653 |
|
[CC] GO:0031982 |
None
|
ABCB1, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALPL, AOX1, APP, AXL, BACE1, CA1, CA2, CA4, CA6, CBR1, DRD2, DRD3, DUSP3, EGFR, F3, FABP3, FABP4, FUCA1, GAA, GBA, GLO1, GPER1, GRIA4, GRM5, HSPA1A, HTR2A, HTR4, INSR, KDR, KIT, MAOB, MGAM, MIF, MMP9, NISCH, NQO2, PTGS1, PTPN1, PTPRS, SHBG, SLC1A1, SRC, TUBB3, TYR |
2.4125 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.40592 |
|
[CC] GO:0044422 |
organelle part
|
ABCG2, AKR1B1, ALOX5, AOX1, APEX1, APP, AR, AURKB, BACE1, BCL2, CA4, CA5A, CA5B, CA9, CACNA1C, CDC25B, CDK6, CES2, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD5, DUSP3, DYRK1A, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GPER1, GRIA2, GRIA4, HASPIN, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HSPA1A, INSR, MAOA, MAOB, MCL1, MGAM, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR |
2.29068 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CES2, CYP19A1, FLT3, GBA2, GPER1, GRIK5, HMGCR, HSD17B3, HSPA1A, HTR5A, KDR, PTGS2, PTPN1, XDH |
2.28682 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, DRD5, GPER1, INSR, SRC, TRPV1 |
2.22345 |
|
[CC] GO:0005741 |
None
|
BCL2, CNR1, DAO, MAOA, MAOB, MCL1, PGR |
2.13555 |
|
[CC] GO:0032589 |
None
|
ADORA1, GPER1, INSR, TRPV1 |
2.08402 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.02424 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ABCG2, ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDK6, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, GLO1, HASPIN, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MAOB, MET, MMP1, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
20.3686 |
|
[MF] GO:0030594 |
None
|
CHRM2, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
18.9527 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, RORC, TEK, TRPV1 |
18.7989 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DNMT1, DYRK2, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
17.5598 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CDK6, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, RORC, TEK, TRPV1 |
16.8438 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, RORC, TEK, TRPV1 |
16.7261 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SMAD3, TEK, TRPV1 |
15.8534 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, F10, F3, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HASPIN, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, PTPRS, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
15.5883 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
14.6419 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.2843 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.2843 |
|
[MF] GO:0008227 |
None
|
ADRB1, CHRM2, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.0064 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.0064 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.0064 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRB1, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, TEK, TRPV1 |
13.3024 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRB1, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, TEK, TRPV1 |
13.3024 |
|
[MF] GO:0099528 |
None
|
CHRM2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
13.3024 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK2, DYRK3, ESR1, ESR2, ESRRA, ESRRB, F10, FDPS, GLO1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
13.0783 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, DRD5, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
12.5819 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ABCG2, ACHE, AURKB, AXL, CDK6, CHRM2, CLK1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, DRD1, DRD2, DRD3, DRD5, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, SRC, TEK, TOP2A, TRPV1 |
11.8321 |
|
[MF] GO:0005496 |
steroid binding
|
AR, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC, SHBG |
11.6218 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, MAOA, MAOB, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
11.3411 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
9.80407 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC |
9.61495 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, CLK1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
9.59853 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PTPN1, RORC, SMAD3, TNKS |
8.85237 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
8.83156 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
8.6032 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
8.09213 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ABCG2, ADORA1, ADRB1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FDPS, FLT3, GPER1, HASPIN, HIF1A, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MAOB, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SHBG, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
8.03595 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
7.69017 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
7.69017 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRB1, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DRD5, GPER1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
7.53007 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, TBXAS1, XDH |
7.25395 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.12861 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AKR1C3, AOX1, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, XDH |
7.02124 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4 |
6.97047 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
6.85369 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, GPER1, HSD17B1, IGF1R, INSR, NQO2, NR3C1, SHBG |
6.84428 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, HMGCR, HSD11B2, HSD17B1, MAOB, NQO2, POLA1, PTGS1, PTGS2, SRC, TBXAS1, XDH |
6.7893 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DNMT1, DYRK2, DYRK3, ESR1, ESR2, ESRRA, ESRRB, F10, FDPS, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.74656 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, SRC, TEK |
6.70562 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1, POLB |
6.60805 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, ERBB2, INSR, KDR, KIT |
6.48212 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, GPER1, HSD11B2, HSD17B1, NISCH, NR3C1, NR3C2, PGR, PPARA, RORC, SHBG, TRPV1 |
6.45659 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, TBXAS1, TYR |
6.45585 |
|
[MF] GO:0004497 |
monooxygenase activity
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, TBXAS1, TYR |
6.43233 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, SRC, TBXAS1 |
6.28607 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, SRC, TBXAS1 |
5.96233 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
5.94956 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
5.79411 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, SRC, TEK, TERT |
5.6803 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ABCG2, ADORA1, AOX1, AURKB, AXL, CDK6, CLK1, CSNK2A1, DAO, DNMT1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FABP3, FABP4, FLT3, HASPIN, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAOB, MET, NQO2, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, POLA1, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
5.66815 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ABCG2, ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CLK1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FDPS, FLT3, HASPIN, HIF1A, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MAOB, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
5.59209 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, AKR1C3, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.55131 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CLK1, CSNK2A1, DAO, DNMT1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAOB, MET, NQO2, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, POLA1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
5.42139 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CLK1, CSNK2A1, DAO, DNMT1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAOB, MET, NQO2, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, POLA1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
5.42093 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1C3, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.37179 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
5.28123 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
AKR1C3, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.18791 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ABCG2, ALOX15, AOX1, APP, AURKB, AXL, CDK6, CLK1, CSNK2A1, DAO, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, F10, F3, FABP3, FABP4, FLT3, HASPIN, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MAOB, MET, NISCH, NQO2, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, PTPRS, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
5.07669 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1B10, AKR1C3, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CBR1, CDC25B, CDK6, CES2, CHRM2, CLK1, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FDPS, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HASPIN, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MAOB, MCL1, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NISCH, NQO2, NR3C1, NR3C2, NUAK1, PDE5A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SHBG, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.91684 |
|
[MF] GO:1901338 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5 |
4.58443 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, KIT, MAOB, MCL1, MET, MIF, MMP9, NISCH, NQO2, PGR, PTGS2, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
4.57966 |
|
[MF] GO:0004712 |
protein serine/threonine/tyrosine kinase activity
|
AURKB, CLK1, DYRK1A, DYRK1B, DYRK2, DYRK3 |
4.26038 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB |
4.16405 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
4.09741 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.01184 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.87606 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
3.66212 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2, GPER1 |
3.6316 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP3A4 |
3.50109 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRB1, APP, AR, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRB, F3, GRM5, HIF1A, HMGCR, HSPA1A, KIT, MET, MIF, NR3C1, PGR, POLA1, POLB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.45854 |
|
[MF] GO:0047035 |
testosterone dehydrogenase (NAD+) activity
|
AKR1C3, HSD17B2, HSD17B3 |
3.36564 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
3.33045 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1 |
3.30848 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.22976 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.12717 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ABCG2, ACHE, ADORA1, ADRB1, AOX1, AR, AXL, BCL2, DAO, DRD2, EGFR, ERBB2, FLT3, HIF1A, HMGCR, KIT, MAOB, MCL1, NQO2, PTGS2, SMAD3, TERT, TOP2A, TYR, XDH |
3.10619 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, MAOB, NQO2, XDH |
3.0006 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AKR1C3, AOX1, XDH |
2.99672 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.9743 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
2.82656 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ABCG2, ADORA1, APP, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, POLA1, PTPRS, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.77325 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
2.74141 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, ERBB2, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.74014 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
ADRB1, EGFR, ERBB2, INSR, KDR, KIT, SMAD3 |
2.71116 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
2.68243 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.66597 |
|
[MF] GO:0045550 |
None
|
AKR1B10, AKR1C3 |
2.66597 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.66597 |
|
[MF] GO:0047977 |
hepoxilin-epoxide hydrolase activity
|
ALOX12, ALOX15 |
2.66597 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.66597 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.66597 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.66597 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, HASPIN, NUAK1, PIK3CA, PIM1 |
2.63989 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.59057 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.57296 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE5A, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.56761 |
|
[MF] GO:0051879 |
Hsp90 protein binding
|
CSNK2A1, HIF1A, KDR, NR3C1 |
2.43573 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CLK1, CSNK2A1, DYRK1A, DYRK1B, DYRK2, DYRK3, EGFR, ERBB2, FLT3, HASPIN, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.43005 |
|
[MF] GO:0015926 |
None
|
GAA, GBA2, MGAM |
2.3031 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.26984 |
|
[MF] GO:0047718 |
None
|
AKR1B10, AKR1C3 |
2.26984 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.26984 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.26984 |
|
[MF] GO:0004052 |
arachidonate 12-lipoxygenase activity
|
ALOX12, ALOX15 |
2.26984 |
|
[MF] GO:0047045 |
None
|
AKR1C3, HSD17B3 |
2.26984 |
|
[MF] GO:0032450 |
None
|
GAA, MGAM |
2.26984 |
|
[MF] GO:0051120 |
hepoxilin A3 synthase activity
|
ALOX12, ALOX15 |
2.26984 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.26984 |
|
[MF] GO:0004348 |
None
|
GBA, GBA2 |
2.26984 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HIF1A, HSPA1A, KDR, NR3C1 |
2.26414 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ABCG2, ACHE, AOX1, BCL2, DRD2, FLT3, HMGCR, KIT, MAOB, MCL1, NQO2, PTGS2, SMAD3, TERT, TOP2A, TYR, XDH |
2.2574 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, NISCH, PPARA, PTPN1, SMAD3, SRC |
2.2574 |
|
[MF] GO:0016641 |
None
|
DAO, MAOA, MAOB |
2.15821 |
|
[MF] GO:0050660 |
flavin adenine dinucleotide binding
|
AOX1, DAO, MAOB, NQO2, XDH |
2.08531 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, NISCH, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.06935 |
|
[MF] GO:0019903 |
protein phosphatase binding
|
BCL2, EGFR, ERBB2, HMGCR, MET, PTPN1 |
2.02424 |
|
[MF] GO:0001588 |
None
|
DRD1, DRD5 |
2.0185 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.0185 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.0185 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.0185 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.0185 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.0185 |
|
[MF] GO:0004558 |
None
|
GAA, MGAM |
2.0185 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.0185 |
