Component: Pericarpium citri reticulatae 陈皮


Description of the Component

Component ID
TCMH243
Latin Name
Pericarpium citri reticulatae
English Name
Dried tangerine peel
Chinese Pinyin Name
Chen Pi
中文名
陈皮
TCM Properties
Warm,Pungent,Bitter
TCM Meridians
Lung,Spleen
Therapeutic Class English
Regulation of qi
Therapeutic Class Chinese
理气
Functions
regulate the flow of qi, invigorate the spleen function, eliminate damp, and resolve phlegm
Toxicity
NA
Geo-authentic habitats (道地产区)
Guangdong Province,Hong Kong,Macao
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT599 UBE2N Ubiquitin-conjugating enzyme E2 N Transferase P61088
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1109 Reverse transcriptase
TCMT1112 Quinolone resistance protein norA
TCMT1178 Actinomyces viscosus
TCMT1209 Staphylococcus haemolyticus
TCMT1210 Streptococcus sobrinus
TCMT1211 Fusobacterium nucleatum
TCMT1218 Staphylococcus aureus
TCMT1221 Human herpesvirus 4
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1318 Human T-lymphotropic virus 1
TCMT1321 Staphylococcus hominis
TCMT1343 Staphylococcus simulans
TCMT1344 Staphylococcus sciuri
TCMT1370 Prevotella melaninogenica
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC922
Formula: C10H16O

Ingredient ID: TCMC791
Formula: C40H56

Ingredient ID: TCMC6824
Formula: C12H10O5

Ingredient ID: TCMC6814
Formula: C28H34O15

Ingredient ID: TCMC6582
Formula: C19H18O6

Ingredient ID: TCMC6578
Formula: C21H22O8

Ingredient ID: TCMC6574
Formula: C17H14O6

Ingredient ID: TCMC6552
Formula: C15H22O

Ingredient ID: TCMC6518
Formula: C18H16O5

Ingredient ID: TCMC5779
Formula: C25H28O8

Ingredient ID: TCMC5428
Formula: C18H16O6

Ingredient ID: TCMC5082
Formula: C10H14

Ingredient ID: TCMC4925
Formula: C20H20O8

Ingredient ID: TCMC4924
Formula: C9H11NO2

Ingredient ID: TCMC4337
Formula: C15H24

Ingredient ID: TCMC4136
Formula: C11H16O

Ingredient ID: TCMC4133
Formula: C10H16O

Ingredient ID: TCMC3824
Formula: C10H16

Ingredient ID: TCMC3745
Formula: C28H34O15

Ingredient ID: TCMC3506
Formula: C9H18O

Ingredient ID: TCMC3452
Formula: C19H18O8

Ingredient ID: TCMC3234
Formula: C19H18O7

Ingredient ID: TCMC3141
Formula: C8H18O

Ingredient ID: TCMC3126
Formula: C10H16

Ingredient ID: TCMC3115
Formula: C10H18

Ingredient ID: TCMC3079
Formula: C8H16O

Ingredient ID: TCMC2929
Formula: C10H14O

Ingredient ID: TCMC2925
Formula: C10H20O

Ingredient ID: TCMC2660
Formula: C11H20O

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2539
Formula: C10H16

Ingredient ID: TCMC2281
Formula: C28H34O9

Ingredient ID: TCMC2166
Formula: C10H14O

Ingredient ID: TCMC2123
Formula: C20H20O7

Ingredient ID: TCMC1860
Formula: C10H14O

Ingredient ID: TCMC1737
Formula: C10H18O

Ingredient ID: TCMC1735
Formula: C27H32O14

Ingredient ID: TCMC1608
Formula: C10H16

Ingredient ID: TCMC1493
Formula: C10H18O

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC791 C40H56 Beta Carotene 536.44 8.935 5.86 14.734 0 0 0 20 2 40 1
TCMC922 C10H16O Citral 152.12 2.4893 2.45 2.701 1 0 17.07 7 0 11 0
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1608 C10H16 Myrcene 136.13 3.0936 2.56 4.17 0 0 0 6 0 10 0
TCMC1735 C27H32O14 Naringin 580.18 -4.8082 2.89 -1.045 10 8 225.06 15 5 41 1
TCMC1737 C10H18O Nerol 154.14 2.3397 2.45 2.524 1 1 20.23 8 0 11 0
TCMC1860 C10H14O Perillaldehyde 150.1 1.308 2.45 2.355 1 0 17.07 3 1 11 0
TCMC2123 C20H20O7 Tangeretin 372.12 -0.7626 2.89 2.236 1 0 72.45 11 3 27 0
TCMC2166 C10H14O Thymol 150.1 0.7546 2.45 3.556 0 1 20.23 5 1 11 0
TCMC2281 C28H34O9 Nomilin 514.22 0.2549 3.55 2.498 8 0 121.64 9 6 37 0
TCMC2539 C10H16 Gamma-Terpinene 136.13 2.4017 2.56 3.852 0 0 0 4 1 10 0
TCMC2541 C10H18O Alpha-Terpineol 154.14 1.1223 2.45 2.369 1 1 20.23 5 1 11 0
TCMC2660 C11H20O (E)-2-Undecenal 168.15 -1.2524 2.56 4.695 1 0 17.07 9 0 12 0
TCMC2925 C10H20O Decanal 156.1514153 0.6746 2.45 3.52 1 1 20.23 1 1 11 0
TCMC2929 C10H14O Carvacrol 150.1044651 1.5954 2.45 1.756 1 0 17.07 1 1 11 0
TCMC3079 C8H16O Octanal 128.1201151 -2.5267 2.23 2.467 1 1 20.23 0 1 9 0
TCMC3115 C10H18 Α-Thujene 138.1408506 -0.3342 2.56 4.82 0 0 0 4 0 10 0
TCMC3126 C10H16 1-Isopropyl-4-Methylenebicyclo[3.1.0]Hexane,Sabinene 136.1252005 1.0301 2.56 4.222 0 0 0 1 2 10 0
TCMC3141 C8H18O Octanol 130.1357652 1.9131 2.23 2.62 1 0 9.23 2 0 9 0
TCMC3234 C19H18O7 4'-Hydroxy-5,6,7,8-Tetramethoxyflavone 357.0974279 -0.3643 2.78 1.477 6 0 105.87 7 3 26 0
TCMC3452 C19H18O8 5-Hydroxy-6,7,8,4'-Tetramethoxyflavone,Skullcapflavone I,Skullcapflavone II 374.1001675 -1.2644 2.67 0.313 1 2 94.45 5 3 27 0
TCMC3506 C9H18O Nonaylaldehyde 142.1357652 2.2165 2.34 2.615 1 0 17.07 2 0 10 0
TCMC3745 C28H34O15 Neohesperidin 610.1897704 -4.86 2.89 -1.489 10 8 234.29 7 5 43 1
TCMC3824 C10H16 (-)-Nopinene,(1S,5S)-6,6-Dimethyl-2-Methylenebicyclo[3.1.1]Heptane,Β-Pinene 136.1252005 1.3695 2.56 4.222 0 0 0 0 1 10 0
TCMC4133 C10H16O Citral,Neral 152.1201151 2.4893 2.45 2.701 1 0 17.07 4 0 11 0
TCMC4136 C11H16O 4-(1,1-Dimethylethyl)-Benzenemethanol 164.1201151 2.7325 2.56 1.998 1 0 17.07 0 1 12 0
TCMC4337 C15H24 (E,E)-Α-Farnesene,3,7,11-Trimethyldodeca-1,3,6,10-Tetraene,Farnesene,Α-Farnesene 204.1878008 4.4725 3.11 6.136 0 0 0 6 0 15 1
TCMC4924 C9H11NO2 Benzoic Acid 2-Methylaminomethylester 165.0789786 0.3181 2.12 1.639 3 0 39.19 3 1 12 0
TCMC4925 C20H20O8 5-Hydroxy-6,7,8,3',4'-Pentamethoxyflavone 388.1158176 -0.3375 2.78 2.481 4 0 89.52 7 3 28 0
TCMC5082 C10H14 P-Cymol 134.1095504 1.942 2.56 4.27 0 0 0 1 1 10 0
TCMC5428 C18H16O6 5-Hydroxy-7,8,4'-Trimethoxyflavanone 328.0946882 -0.4735 2.78 2.899 1 1 64.99 4 3 24 0
TCMC5779 C25H28O8 Limonin 456.1784179 0.0393 3.33 3.381 5 0 95.97 9 3 33 0
TCMC6518 C18H16O5 5,7,4'-Trimethoxyflavone 312.0997736 -1.7192 2.89 2.523 4 2 83.83 3 3 23 0
TCMC6552 C15H22O 2,6,10-Trimethyl-2,6,9,11-Dodecatetraenal 218.1670653 2.3344 3 4.187 1 0 17.07 2 2 16 0
TCMC6574 C17H14O6 5,4'-Dihydroxy-7,8-Dimethoxy Flavone 314.0790382 -0.9574 2.67 2.232 4 2 83.83 4 3 23 0
TCMC6578 C21H22O8 Citromitin 402.1314677 -1.3845 2.89 3.139 8 2 110.13 7 3 29 0
TCMC6582 C19H18O6 5,7,8,4'-Tetramethoxyflavone 342.1103383 -0.7688 2.89 3.238 2 4 107.22 6 2 25 0
TCMC6814 C28H34O15 Hesperetin-7-O-Rutinoside 610.1897704 -4.86 2.89 -1.489 10 8 234.29 7 5 43 1
TCMC6824 C12H10O5 5,5'-Oxydimethylene-Bis(2-Furaldehyde) 233.0449984 -1.7286 2.23 3.602 5 0 81.65 2 2 17 0

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1. General Information of the Component  
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