Component ID |
TCMH243 |
Latin Name |
Pericarpium citri reticulatae |
English Name |
Dried tangerine peel |
Chinese Pinyin Name |
Chen Pi |
中文名 |
陈皮 |
TCM Properties |
Warm,Pungent,Bitter |
TCM Meridians |
Lung,Spleen |
Therapeutic Class English |
Regulation of qi |
Therapeutic Class Chinese |
理气 |
Functions |
regulate the flow of qi, invigorate the spleen function, eliminate damp, and resolve phlegm |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
Guangdong Province,Hong Kong,Macao |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
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Barcode Source |
Prescription ID | Prescription English Name | Prescription Chinese Name |
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Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT265 | GSK3B | Glycogen synthase kinase-3 beta | Kinase | P49841 |
TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
TCMT327 | TRPV1 | Vanilloid receptor | Ion channel | Q8NER1 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT599 | UBE2N | Ubiquitin-conjugating enzyme E2 N | Transferase | P61088 |
TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
Target ID | Target Name |
---|---|
TCMT1109 | Reverse transcriptase |
TCMT1112 | Quinolone resistance protein norA |
TCMT1178 | Actinomyces viscosus |
TCMT1209 | Staphylococcus haemolyticus |
TCMT1210 | Streptococcus sobrinus |
TCMT1211 | Fusobacterium nucleatum |
TCMT1218 | Staphylococcus aureus |
TCMT1221 | Human herpesvirus 4 |
TCMT1223 | Staphylococcus epidermidis |
TCMT1226 | Klebsiella pneumoniae |
TCMT1229 | Enterococcus faecalis |
TCMT1246 | Escherichia coli |
TCMT1251 | Candida albicans |
TCMT1253 | Penicillium chrysogenum |
TCMT1255 | Human immunodeficiency virus 1 |
TCMT1318 | Human T-lymphotropic virus 1 |
TCMT1321 | Staphylococcus hominis |
TCMT1343 | Staphylococcus simulans |
TCMT1344 | Staphylococcus sciuri |
TCMT1370 | Prevotella melaninogenica |
TCMT1448 | Enterobacter aerogenes |
TCMT1454 | Bacillus subtilis |
TCMT1455 | Mycobacterium tuberculosis H37Rv |
TCMT1462 | Streptococcus mutans |
Ingredient ID: TCMC922
Formula: C10H16O
Ingredient ID: TCMC791
Formula: C40H56
Ingredient ID: TCMC6824
Formula: C12H10O5
Ingredient ID: TCMC6814
Formula: C28H34O15
Ingredient ID: TCMC6582
Formula: C19H18O6
Ingredient ID: TCMC6578
Formula: C21H22O8
Ingredient ID: TCMC6574
Formula: C17H14O6
Ingredient ID: TCMC6552
Formula: C15H22O
Ingredient ID: TCMC6518
Formula: C18H16O5
Ingredient ID: TCMC5779
Formula: C25H28O8
Ingredient ID: TCMC5428
Formula: C18H16O6
Ingredient ID: TCMC5082
Formula: C10H14
Ingredient ID: TCMC4925
Formula: C20H20O8
Ingredient ID: TCMC4924
Formula: C9H11NO2
Ingredient ID: TCMC4337
Formula: C15H24
Ingredient ID: TCMC4136
Formula: C11H16O
Ingredient ID: TCMC4133
Formula: C10H16O
Ingredient ID: TCMC3824
Formula: C10H16
Ingredient ID: TCMC3745
Formula: C28H34O15
Ingredient ID: TCMC3506
Formula: C9H18O
Ingredient ID: TCMC3452
Formula: C19H18O8
Ingredient ID: TCMC3234
Formula: C19H18O7
Ingredient ID: TCMC3141
Formula: C8H18O
Ingredient ID: TCMC3126
Formula: C10H16
Ingredient ID: TCMC3115
Formula: C10H18
Ingredient ID: TCMC3079
Formula: C8H16O
Ingredient ID: TCMC2929
Formula: C10H14O
Ingredient ID: TCMC2925
Formula: C10H20O
Ingredient ID: TCMC2660
Formula: C11H20O
Ingredient ID: TCMC2541
Formula: C10H18O
Ingredient ID: TCMC2539
Formula: C10H16
Ingredient ID: TCMC2281
Formula: C28H34O9
Ingredient ID: TCMC2166
Formula: C10H14O
Ingredient ID: TCMC2123
Formula: C20H20O7
Ingredient ID: TCMC1860
Formula: C10H14O
Ingredient ID: TCMC1737
Formula: C10H18O
Ingredient ID: TCMC1735
Formula: C27H32O14
Ingredient ID: TCMC1608
Formula: C10H16
Ingredient ID: TCMC1493
Formula: C10H18O
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC791 | C40H56 | Beta Carotene | 536.44 | 8.935 | 5.86 | 14.734 | 0 | 0 | 0 | 20 | 2 | 40 | 1 |
TCMC922 | C10H16O | Citral | 152.12 | 2.4893 | 2.45 | 2.701 | 1 | 0 | 17.07 | 7 | 0 | 11 | 0 |
TCMC1493 | C10H18O | Linalool (+) | 154.14 | 2.4692 | 2.45 | 2.468 | 1 | 1 | 20.23 | 8 | 0 | 11 | 0 |
TCMC1608 | C10H16 | Myrcene | 136.13 | 3.0936 | 2.56 | 4.17 | 0 | 0 | 0 | 6 | 0 | 10 | 0 |
TCMC1735 | C27H32O14 | Naringin | 580.18 | -4.8082 | 2.89 | -1.045 | 10 | 8 | 225.06 | 15 | 5 | 41 | 1 |
TCMC1737 | C10H18O | Nerol | 154.14 | 2.3397 | 2.45 | 2.524 | 1 | 1 | 20.23 | 8 | 0 | 11 | 0 |
TCMC1860 | C10H14O | Perillaldehyde | 150.1 | 1.308 | 2.45 | 2.355 | 1 | 0 | 17.07 | 3 | 1 | 11 | 0 |
TCMC2123 | C20H20O7 | Tangeretin | 372.12 | -0.7626 | 2.89 | 2.236 | 1 | 0 | 72.45 | 11 | 3 | 27 | 0 |
TCMC2166 | C10H14O | Thymol | 150.1 | 0.7546 | 2.45 | 3.556 | 0 | 1 | 20.23 | 5 | 1 | 11 | 0 |
TCMC2281 | C28H34O9 | Nomilin | 514.22 | 0.2549 | 3.55 | 2.498 | 8 | 0 | 121.64 | 9 | 6 | 37 | 0 |
TCMC2539 | C10H16 | Gamma-Terpinene | 136.13 | 2.4017 | 2.56 | 3.852 | 0 | 0 | 0 | 4 | 1 | 10 | 0 |
TCMC2541 | C10H18O | Alpha-Terpineol | 154.14 | 1.1223 | 2.45 | 2.369 | 1 | 1 | 20.23 | 5 | 1 | 11 | 0 |
TCMC2660 | C11H20O | (E)-2-Undecenal | 168.15 | -1.2524 | 2.56 | 4.695 | 1 | 0 | 17.07 | 9 | 0 | 12 | 0 |
TCMC2925 | C10H20O | Decanal | 156.1514153 | 0.6746 | 2.45 | 3.52 | 1 | 1 | 20.23 | 1 | 1 | 11 | 0 |
TCMC2929 | C10H14O | Carvacrol | 150.1044651 | 1.5954 | 2.45 | 1.756 | 1 | 0 | 17.07 | 1 | 1 | 11 | 0 |
TCMC3079 | C8H16O | Octanal | 128.1201151 | -2.5267 | 2.23 | 2.467 | 1 | 1 | 20.23 | 0 | 1 | 9 | 0 |
TCMC3115 | C10H18 | Α-Thujene | 138.1408506 | -0.3342 | 2.56 | 4.82 | 0 | 0 | 0 | 4 | 0 | 10 | 0 |
TCMC3126 | C10H16 | 1-Isopropyl-4-Methylenebicyclo[3.1.0]Hexane,Sabinene | 136.1252005 | 1.0301 | 2.56 | 4.222 | 0 | 0 | 0 | 1 | 2 | 10 | 0 |
TCMC3141 | C8H18O | Octanol | 130.1357652 | 1.9131 | 2.23 | 2.62 | 1 | 0 | 9.23 | 2 | 0 | 9 | 0 |
TCMC3234 | C19H18O7 | 4'-Hydroxy-5,6,7,8-Tetramethoxyflavone | 357.0974279 | -0.3643 | 2.78 | 1.477 | 6 | 0 | 105.87 | 7 | 3 | 26 | 0 |
TCMC3452 | C19H18O8 | 5-Hydroxy-6,7,8,4'-Tetramethoxyflavone,Skullcapflavone I,Skullcapflavone II | 374.1001675 | -1.2644 | 2.67 | 0.313 | 1 | 2 | 94.45 | 5 | 3 | 27 | 0 |
TCMC3506 | C9H18O | Nonaylaldehyde | 142.1357652 | 2.2165 | 2.34 | 2.615 | 1 | 0 | 17.07 | 2 | 0 | 10 | 0 |
TCMC3745 | C28H34O15 | Neohesperidin | 610.1897704 | -4.86 | 2.89 | -1.489 | 10 | 8 | 234.29 | 7 | 5 | 43 | 1 |
TCMC3824 | C10H16 | (-)-Nopinene,(1S,5S)-6,6-Dimethyl-2-Methylenebicyclo[3.1.1]Heptane,Β-Pinene | 136.1252005 | 1.3695 | 2.56 | 4.222 | 0 | 0 | 0 | 0 | 1 | 10 | 0 |
TCMC4133 | C10H16O | Citral,Neral | 152.1201151 | 2.4893 | 2.45 | 2.701 | 1 | 0 | 17.07 | 4 | 0 | 11 | 0 |
TCMC4136 | C11H16O | 4-(1,1-Dimethylethyl)-Benzenemethanol | 164.1201151 | 2.7325 | 2.56 | 1.998 | 1 | 0 | 17.07 | 0 | 1 | 12 | 0 |
TCMC4337 | C15H24 | (E,E)-Α-Farnesene,3,7,11-Trimethyldodeca-1,3,6,10-Tetraene,Farnesene,Α-Farnesene | 204.1878008 | 4.4725 | 3.11 | 6.136 | 0 | 0 | 0 | 6 | 0 | 15 | 1 |
TCMC4924 | C9H11NO2 | Benzoic Acid 2-Methylaminomethylester | 165.0789786 | 0.3181 | 2.12 | 1.639 | 3 | 0 | 39.19 | 3 | 1 | 12 | 0 |
TCMC4925 | C20H20O8 | 5-Hydroxy-6,7,8,3',4'-Pentamethoxyflavone | 388.1158176 | -0.3375 | 2.78 | 2.481 | 4 | 0 | 89.52 | 7 | 3 | 28 | 0 |
TCMC5082 | C10H14 | P-Cymol | 134.1095504 | 1.942 | 2.56 | 4.27 | 0 | 0 | 0 | 1 | 1 | 10 | 0 |
TCMC5428 | C18H16O6 | 5-Hydroxy-7,8,4'-Trimethoxyflavanone | 328.0946882 | -0.4735 | 2.78 | 2.899 | 1 | 1 | 64.99 | 4 | 3 | 24 | 0 |
TCMC5779 | C25H28O8 | Limonin | 456.1784179 | 0.0393 | 3.33 | 3.381 | 5 | 0 | 95.97 | 9 | 3 | 33 | 0 |
TCMC6518 | C18H16O5 | 5,7,4'-Trimethoxyflavone | 312.0997736 | -1.7192 | 2.89 | 2.523 | 4 | 2 | 83.83 | 3 | 3 | 23 | 0 |
TCMC6552 | C15H22O | 2,6,10-Trimethyl-2,6,9,11-Dodecatetraenal | 218.1670653 | 2.3344 | 3 | 4.187 | 1 | 0 | 17.07 | 2 | 2 | 16 | 0 |
TCMC6574 | C17H14O6 | 5,4'-Dihydroxy-7,8-Dimethoxy Flavone | 314.0790382 | -0.9574 | 2.67 | 2.232 | 4 | 2 | 83.83 | 4 | 3 | 23 | 0 |
TCMC6578 | C21H22O8 | Citromitin | 402.1314677 | -1.3845 | 2.89 | 3.139 | 8 | 2 | 110.13 | 7 | 3 | 29 | 0 |
TCMC6582 | C19H18O6 | 5,7,8,4'-Tetramethoxyflavone | 342.1103383 | -0.7688 | 2.89 | 3.238 | 2 | 4 | 107.22 | 6 | 2 | 25 | 0 |
TCMC6814 | C28H34O15 | Hesperetin-7-O-Rutinoside | 610.1897704 | -4.86 | 2.89 | -1.489 | 10 | 8 | 234.29 | 7 | 5 | 43 | 1 |
TCMC6824 | C12H10O5 | 5,5'-Oxydimethylene-Bis(2-Furaldehyde) | 233.0449984 | -1.7286 | 2.23 | 3.602 | 5 | 0 | 81.65 | 2 | 2 | 17 | 0 |