TCM Prescription: Five Skin Drink



Prescription Description
Prescription IDTCMFx1737
Pinyin NameWu Pi Yin
Chinese Name五皮饮
English NameFive Skin Drink
Function Description
IndicationsNone
Disease ICD-11 Category
Human Tissues Associated with Indication
ReferenceChinese Classical Prescriptions
Reference Book/linkISBN 7-5023-3930-2
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH2629 Cortex mori radicis praeparata 桑白皮 TCMH2629
TCMH1065 Cortex zingiberis 姜皮 TCMH1065
TCMH357 Pericarpium arecae 大腹皮 TCMH357
TCMH607 Exodermis poria 茯苓皮 TCMH607
TCMH243 Pericarpium citri reticulatae 陈皮 TCMH243
Reference: Chinese Classical Prescriptions

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT551 CHRM4 Muscarinic acetylcholine receptor M4 GPCR P08173
TCMT599 UBE2N Ubiquitin-conjugating enzyme E2 N Transferase P61088
TCMT807 SLC22A12 Solute carrier family 22 member 12 Transporter Q96S37
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1178 Actinomyces viscosus
TCMT1209 Staphylococcus haemolyticus
TCMT1210 Streptococcus sobrinus
TCMT1211 Fusobacterium nucleatum
TCMT1218 Staphylococcus aureus
TCMT1221 Human herpesvirus 4
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1318 Human T-lymphotropic virus 1
TCMT1321 Staphylococcus hominis
TCMT1343 Staphylococcus simulans
TCMT1344 Staphylococcus sciuri
TCMT1370 Prevotella melaninogenica
TCMT1438 Plasmodium falciparum
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1462 Streptococcus mutans

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway