Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC761	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 3920 (nM), Ref: 15658857
TCMC719	TCMT292	Muscarinic acetylcholine receptor M1	Homo sapiens	Ki: 14 (nM), Ref: 10891110 IC50: 115 (nM), Ref: 11597415
TCMC719	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 40 (nM), Ref: 10891110 Ki: 40 (nM), Ref: 9622546 Ki: 2454.71 (nM), Ref: 18182302
TCMC719	TCMT551	Muscarinic acetylcholine receptor M4	Homo sapiens	Ki: 2400 (nM), Ref: 10891110 Ki: 26 (nM), Ref: 10891110 Ki: 2400 (nM), Ref: 9622546
TCMC1735	TCMT599	Ubiquitin-conjugating enzyme E2 N	Homo sapiens	IC50: 8695 (nM), Ref: IC50: 5771 (nM), Ref: IC50: 6662 (nM), Ref:
TCMC845	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 630 (nM), Ref: 19231207
TCMC2070	TCMT327	Vanilloid receptor	Homo sapiens	IC50: 290 (nM), Ref: 22257892
TCMC339	TCMT206	Cytochrome P450 2A6	Homo sapiens	IC50: 10000 (nM), Ref: 15658857 IC50: 10000 (nM), Ref: 19110342
TCMC238	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 500 (nM), Ref: 21282059 Ki: 500 (nM), Ref: 22245047
TCMC238	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 8630 (nM), Ref: 21282059
TCMC238	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8360 (nM), Ref: 21282059
TCMC238	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6830 (nM), Ref: 22668600
TCMC238	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7250 (nM), Ref: 22668600
TCMC1597	TCMT807	Solute carrier family 22 member 12	Homo sapiens	IC50: 2000 (nM), Ref: 17325024 Ki: 5740 (nM), Ref: 17325024
TCMC1597	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 2927.18 (nM), Ref:
TCMC1597	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 2988.26 (nM), Ref:
TCMC1597	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 1600 (nM), Ref: 24900447
TCMC1597	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 1600 (nM), Ref: 26322379
TCMC1597	TCMT283	Receptor-type tyrosine-protein phosphatase S	Homo sapiens	IC50: 4300 (nM), Ref: 26602279
TCMC248	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 8210 (nM), Ref: 21282059
TCMC248	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3350 (nM), Ref: 21282059
TCMC248	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4150 (nM), Ref: 21282059
TCMC248	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4020 (nM), Ref: 21282059
TCMC248	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6790 (nM), Ref: 22668600
TCMC248	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3880 (nM), Ref: 22668600
TCMC871	TCMT33	Cytochrome P450 3A4	Homo sapiens	Ki: 4300 (nM), Ref: 22531045
TCMC871	TCMT87	Cytochrome P450 2C9	Homo sapiens	Ki: 9200 (nM), Ref: 22531045
TCMC871	TCMT301	Prostaglandin E synthase	Homo sapiens	IC50: 5000 (nM), Ref: 10.1039/C5MD00278H
TCMC1611	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1611	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2281	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 0.00342 (ug/ml), Ref: 21334901 IC50: 0.00356 (ug/ml), Ref: 21334901
TCMC2123	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC2313	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC2313	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC845	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 1522419 MIC: 6.25 (ug/ml), Ref: 1522419
TCMC845	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 25 (ug/ml), Ref: 1522419 MIC: 1.57 (ug/ml), Ref: 1522419
TCMC60	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC60	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC2539	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2281	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 13 (ug/ml), Ref: 21334901
TCMC2281	TCMT1318	Human T-lymphotropic virus 1	Human T-lymphotropic virus 1	IC50: 3.98 (ug/ml), Ref: 21334901
TCMC2166	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 50 (ug/ml), Ref: 8864235
TCMC2166	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1321	Staphylococcus hominis	Staphylococcus hominis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906 MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1209	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1343	Staphylococcus simulans	Staphylococcus simulans	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1344	Staphylococcus sciuri	Staphylococcus sciuri	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1246	Escherichia coli	Escherichia coli	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2644	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 12.5 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC2660	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 6.25 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC395	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC2671	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC2671	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 50 (ug/ml), Ref: 10.1021/np50124a013
TCMC791	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 12.7 (nM), Ref: 17503850