Component: Caulis perillae frutescentis 苏梗


Description of the Component

Component ID
TCMH2039
Latin Name
Caulis perillae frutescentis
English Name
stem of common perilla
Chinese Pinyin Name
Su Geng
中文名
苏梗
TCM Properties
Minor Warm,Pungent,Sweet
TCM Meridians
Lung,Spleen,Stomach
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx1985 Pain Relieving recipe
TCMF1897 Radix Bupleuri Liver Clearing Decoction 柴胡清肝饮
TCMFx1967 Stomach Tonification Decoction 养胃理气汤

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1245 Phytophthora cactorum
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1408 Colletotrichum gloeosporioides
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC761
Formula: C7H6O

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2539
Formula: C10H16

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC208
Formula: C10H16O

Ingredient ID: TCMC1737
Formula: C10H18O

Ingredient ID: TCMC1611
Formula: C14H28O2

Ingredient ID: TCMC1578
Formula: C11H14O2

Ingredient ID: TCMC1493
Formula: C10H18O

Ingredient ID: TCMC1159
Formula: C10H12O2

Ingredient ID: TCMC1157
Formula: C10H18O

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC208 C10H16O [(4R)-4-Prop-1-En-2-Ylcyclohexen-1-Yl]Methanol 152.12 1.0517 2.45 1.848 1 1 20.23 4 1 11 0
TCMC761 C7H6O Benzaldehyde 106.04 -0.1924 2.12 3.08 1 0 17.07 1 1 8 0
TCMC1157 C10H18O Eucalyptol 154.14 1.3109 2.45 2.595 1 0 9.23 3 0 11 0
TCMC1159 C10H12O2 Eugenol 164.08 0.5166 2.34 2.484 0 1 29.46 5 1 12 0
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1578 C11H14O2 Methyleugenol 178.1 0.9251 2.45 3.003 0 0 18.46 6 1 13 0
TCMC1611 C14H28O2 Myristic Acid 228.21 -3.3217 2.78 6.432 2 1 37.3 14 0 16 2
TCMC1737 C10H18O Nerol 154.14 2.3397 2.45 2.524 1 1 20.23 8 0 11 0
TCMC2324 C10H16 Limonene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC2539 C10H16 Gamma-Terpinene 136.13 2.4017 2.56 3.852 0 0 0 4 1 10 0
TCMC2541 C10H18O Alpha-Terpineol 154.14 1.1223 2.45 2.369 1 1 20.23 5 1 11 0

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)