Component: Radix et rhizoma rhodiolae 红景天


Description of the Component

Component ID
 TCMH873
Latin Name
 Radix et rhizoma rhodiolae
English Name
 all - grass of rhodiola
Chinese Pinyin Name
 Hong Jing Tian
中文名
 红景天
TCM Properties
 Minor cold,Sweet,Punkery
TCM Meridians
 Lung,Liver,Kidney
Therapeutic Class English
 For tonifying weakness
Therapeutic Class Chinese
 补虚
Functions
 For tonifying qi
Toxicity
 NA
Geo-authentic habitats (道地产区)
 NA
Reference
 Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF7031 Jing Tian Qing Fei Capsules 景天清肺胶囊
TCMFx1336 Jiuwei Shihuihua Powder 九味石灰华散
TCMFx2119 Jiuwei Shihuihua Powder 九味石灰华散
TCMFx571 Lian Hua Qing Wen Capsule 连花清瘟胶囊
TCMFx572 Lian Hua Qing Wen Granules 连花清瘟颗粒
TCMFx555 Lian Hua Qing Wen Tablet 连花清瘟片
TCMF6871 Tian Qi Recipe 天杞合剂
TCMF6962 Tong Mai Qiang Shen Wine 通脉强肾酒
TCMFx377 Xin Nao Xin Capsule 心脑欣胶囊
TCMFx49 Xin Nao Xin Pills 心脑欣丸
TCMF7097 Xue Shan Jin Luo Han Zhi Tong Tu Mo Ji 雪山金罗汉止痛涂膜剂

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT283 PTPRS Receptor-type tyrosine-protein phosphatase S Hydrolase Q13332
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT591 ESRRA Estrogen-related receptor alpha Nuclear receptor P11474
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1109 Reverse transcriptase
TCMT1121 Sialidase
TCMT1178 Actinomyces viscosus
TCMT1218 Staphylococcus aureus
TCMT1253 Penicillium chrysogenum
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC3563
Formula: C14H20O7

Ingredient ID: TCMC3085
Formula: C9H10O5

Ingredient ID: TCMC2634
Formula: C5H8O

Ingredient ID: TCMC1777
Formula: C8H18O

Ingredient ID: TCMC1493
Formula: C10H18O

Ingredient ID: TCMC1429
Formula: C15H10O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1429 C15H10O6 Kaempferol 286.05 -2.3409 2.45 1.915 2 4 107.22 5 3 21 0
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1777 C8H18O Octanol 130.14 -2.1254 2.23 3.127 1 1 20.23 8 0 9 0
TCMC2634 C5H8O 3-Methyl-(E)-2-Butenal 84.06 1.2571 1.9 0.879 1 0 17.07 3 0 6 0
TCMC3085 C9H10O5 Ethyl Gallate,Gallic Acid Ethyl Ester,Progallin A 198.0528234 -1.1193 1.9 0.746 2 3 86.99 3 1 14 0
TCMC3563 C14H20O7 Rhodioloside,Salidroside 300.120903 -2.4003 2.23 0.063 6 5 119.61 5 2 21 0

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)