Component: Semen astragali complanati 沙苑蒺藜


Description of the Component

Component ID
TCMH1810
Latin Name
Semen astragali complanati
English Name
Seed of flaststem milkvetch
Chinese Pinyin Name
Sha Yuan Ji Li
中文名
沙苑蒺藜
TCM Properties
Warm,Sweet
TCM Meridians
Liver,Kidney
Therapeutic Class English
For tonifying weakness
Therapeutic Class Chinese
补虚
Functions
benefit the liver and the kidney, arrest seminal discharge, restrain urination and improve eyesight
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx1806 Gold Lock Semen Conserving Pills 金锁固精丸
TCMFx7437 Jin Suo Gu Jing Pills 金锁固精丸
TCMF2115 Longevity Powder 龟龄集
TCMF1335 Longevity Powder 龟龄集
TCMFx2331 Pills for Leucorrhagia 内补丸

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1099 Neuraminidase
TCMT1178 Actinomyces viscosus
TCMT1218 Staphylococcus aureus
TCMT1226 Klebsiella pneumoniae
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC855
Formula: C16H12O5

Ingredient ID: TCMC845
Formula: C15H24O

Ingredient ID: TCMC463
Formula: C14H12N2S

Ingredient ID: TCMC2822
Formula: C15H24

Ingredient ID: TCMC2381
Formula: C8H10O

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC2257
Formula: C16H12O6

Ingredient ID: TCMC1512
Formula: C9H11NO2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC463 C14H12N2S 4-(1,3-Benzothiazol-2-Yl)-2-Methylaniline 240.07 0.4827 2.67 3.571 2 1 67.15 3 3 17 0
TCMC845 C15H24O Butylated Hydroxytoluene 220.18 3.2941 3 5.957 0 1 20.23 10 1 16 1
TCMC855 C16H12O5 Calycosin 284.07 -1.6391 2.67 2.031 1 2 75.99 5 3 21 0
TCMC1512 C9H11NO2 L-Phenylalanine 165.08 -1.0844 2.12 0.441 3 2 63.32 5 1 12 0
TCMC2257 C16H12O6 Rhamnocitrin 300.06 -1.9324 2.56 2.434 2 3 96.22 6 3 22 0
TCMC2324 C10H16 Limonene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC2381 C8H10O Phenylethyl Alcohol 122.07 -0.1931 2.23 3.189 1 1 20.23 3 1 9 0
TCMC2822 C15H24 Alpha-Humulone 204.19 4.1708 3.11 5.94 0 0 0 4 1 15 1

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)