Component: Rhizoma dioscoreae 淮山药


Description of the Component

Component ID
TCMH943
Latin Name
Rhizoma dioscoreae
English Name
rhizome of biglcaf yam
Chinese Pinyin Name
Huai Shan Yao
中文名
淮山药
TCM Properties
Mild,Sweet
TCM Meridians
Lung,Spleen,Kidney
Therapeutic Class English
For tonifying weakness
Therapeutic Class Chinese
补虚
Functions
replenish the spleen and stomach, promote fluid secretion and benefit the lung, and strengthen the kidney and restrain seminal discharge
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx1612 Added Flavor DF Powder 加味黛矾散
TCMFx1850 Added Flavor Diarrhea Suppressor 加味腹泻宁
TCMF2188 Appetite Opening Qi Fries
TCMF2062 Bolus as Kidney-Yin-Tonic; Kidney-yin-Tonifying Bolus 左归丸
TCMF2627 Bolus of Dendrobii for Poor Vision 石斛夜光丸
TCMF1447 Bolus of Dendrobii for Poor Vision 石斛夜光丸
TCMF2343 Bolus of Placenta Homimis 河车八味丸
TCMFx1271 Bolus of Six Drugs Including Rehmannia; Six Ingredient Pill with Rehmannia; Pill of Six Ingredients with Rehmannia 六味地黄丸
TCMFx2460 Bone Pain Essential Recipe 骨痛药方
TCMF1349 Brain-Invigorating and Kidney-Tonifying Pill 健脑补肾丸
TCMF2214 Brain-Invigorating and Kidney-Tonifying Pill 健脑补肾丸
TCMF2567 Bushen Yinao Tablets 补肾益脑片
TCMF1414 Bushen Yinao Tablets 补肾益脑片
TCMFx2667 Cattle Gallstone Pill to Clear the Heart 牛黄清心丸
TCMF2323 Codonopsis Poria Atractylodes Powder 参苓白术散
TCMF1372 Codonopsis Poria Atractylodes Powder 参苓白术散
TCMFx2338 Cuscutae Pills 菟丝子丸
TCMF1739 Decoction for Changing Yellow Leukorrhea 易黄汤
TCMF2130 Decoction for Keeping Yin 固阴煎
TCMF1905 Decoction for Nourishing Liver 调肝汤
TCMF2239 Decoction for Treating Leucorrhagia 完带汤
TCMF2288 Diabetes and Kidney Decoction
TCMF2369 Diabetes Relieving Decorction 姜糖饮
TCMFx1727 Discharge Clearing Decoction 清带汤
TCMFx2030 Erlong Zuoci Pills 耳聋左磁丸
TCMF2389 Fetus Support Recipe 保胎方
TCMFx2078 Four Insect Blood Revitalization Decoction 四虫活血汤
TCMF2712 Ginseng, Poria, and Atractylodes Macrocephala Powder from the Analytic Collection 参苓白术散
TCMF2350 Hepatitis B Decoction 益肝汤
TCMFx1950 Hidden True Decoction
TCMF2297 HLC Herb Fries
TCMF2010 HQGD Decoction 黄芪归地汤
TCMFx2210 Hupo Baolong Pills 琥珀抱龙丸
TCMFx1347 Hupo Baolong Pills 琥珀抱龙丸
TCMF1395 Invigorating Spleen Pills 健脾丸
TCMFx2213 Jisheng Shenqi Pills 济生肾气丸
TCMFx1348 Jisheng Shenqi Pills; Kidney Yang Restoring Edema Reducing Pill 济生肾气丸
TCMF1970 Kid Urine Recipe 小儿遗尿方
TCMF2174 Kidney Nourishing Bolus 滋肾蓉精丸
TCMFx2069 Kidney Qi Pill 肾气丸
TCMFx2022 Kidney Qi Pills from the Golden Cabinet 金匮肾气丸
TCMF2306 Kidney Tonification and Brain Benefiting Decoction 补肾益脑汤
TCMF2469 Kidney Tonification Decoction
TCMF2457 Life Support and Soil Care Decoction
TCMF2194 Lung Dispersing Interior Modulation Recipe
TCMFx2043 Maiwei Dihuang Pills 麦味地黄丸
TCMFx1316 Maiwei Dihuang Pills; Lung Kidney Deficiency Cough Pill 麦味地黄丸
TCMF2231 Mi Yuan Fries 秘元煎
TCMFx2166 Nine Herb Chronic Hepatitis Decoction
TCMFx1451 Niuhuang Qingxin Pills 牛黄清心丸
TCMFx2633 Niuhuang Qingxin Pills; Cow-bezoar Sedative Bolus 牛黄清心丸
TCMF2632 Oral Liquid of Chicken Fetus 雏凤精
TCMF1755 Pellet of Poria and Cuscutae 茯菟丹
TCMF2207 Pill for Controlling Fluid 巩堤丸
TCMF2582 Pill for Restoring Yang 还少丹
TCMF2480 Pill for Strengthening Spleen, Pill for Invigorating the Spleen 健脾丸
TCMF2612 Pills of Dioscoreae 薯蓣丸
TCMFx1810 Pills of Six Ingredients with Rehmannia 六味地黄丸
TCMF2515 Plus and Minus DH Decoction 加减地黄汤
TCMF2462 Plus and Minus Eight Pearl Decoction 加减八珍汤
TCMF2569 Plus and Minus Sea Cleansing Bolus 加减清海丸
TCMFx2173 Qi Benefiting and Yin Nourishing Decoction 益气养阴汤
TCMF2109 Qi Lifting Decoction
TCMF2454 Qi Modulation Stomach Benefiting Decoction 调气益胃汤
TCMF2513 Qi Tonification Decoction
TCMF1574 Qian Yin Syrup
TCMFx1352 Qianlieshu Pills 前列舒丸
TCMFx2223 Qianlieshu Pills 前列舒丸
TCMF2084 Qiju Dihuang Pills 杞菊地黄丸
TCMF1325 Qiju Dihuang Pills; Lycium Chrysanthemum Rehmannia Pill 杞菊地黄丸
TCMF2332 Qipi Pills 启脾丸
TCMFx1964 Qiwei Duqi Pills 七味都气丸
TCMFx1300 Qiwei Duqi Pills; Seven Ingredient Qi Restoring Pill 七味都气丸
TCMFx1849 QS Flower Powder Decoction
TCMF2532 Red Jujube and Black Bean Decoction
TCMF1392 Rehmannia Bolus for Improving Eyesight 明目地黄丸
TCMF2473 Rehmannia Bolus for Improving Eyesight 明目地黄丸
TCMF2359 Renshen Jianpi Pills 人参健脾丸
TCMF1377 Renshen Jianpi Pills 人参健脾丸
TCMFx2305 SH Four Gold Decoction
TCMF1888 Shengxue Pills 生血丸
TCMF1437 Shenrong Baotai Pills 参茸保胎丸
TCMF2616 Shenrong Baotai Pills 参茸保胎丸
TCMFx1411 Shenrong Guben Tablets 参茸固本片
TCMFx2557 Shenrong Guben Tablets 参茸固本片
TCMFx2657 Six-Ingredient Pill with Rehmannia 六味地黄丸
TCMF2603 Spasm Relieving Decoction 解痉汤
TCMF2392 Stagnation Desolving and Yin Nourishing Decoction 化瘀养阴汤
TCMF2093 Tablet for Chronic Nephritis 肾康宁片
TCMF1328 Tablet for Chronic Nephritis 肾康宁片
TCMFx2497 Three Excess Remover Decoction
TCMF2028 Tonic Decoction for Debility 大补元煎
TCMF2375 Tonification and Period Modulation Decoction 滋补调经汤
TCMFx1752 Trichosanthis and Dianthi Pills 瓜蒌瞿麦丸
TCMF2610 White Phoenix Bolus of Black-bone Chicken 乌鸡白凤丸
TCMFx2301 XXGJXLP Decoction
TCMF2593 Yin Nourishing Digestion Decoction 滋阴清化汤
TCMFx2183 Yin Nourishing Period Decoction
TCMF2059 Yougui Decoction 右归饮
TCMF1829 Zuogui Decoction 左归饮

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT107 GRIK2 Glutamate receptor ionotropic kainate 2 Ion channel Q13002
TCMT108 GRIA1 Glutamate receptor ionotropic, AMPA 1 Ion channel P42261
TCMT109 GRIA2 Glutamate receptor ionotropic, AMPA 2 Ion channel P42262
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT110 GRIA4 Glutamate receptor ionotropic, AMPA 4 Ion channel P48058
TCMT111 GRIK5 Glutamate receptor ionotropic kainate 5 Ion channel Q16478
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT221 ABCB11 Bile salt export pump Transporter O95342
TCMT267 GABRR1 GABA receptor rho-1 subunit Ion channel P24046
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT316 MTNR1A Melatonin receptor 1A GPCR P48039
TCMT317 MTNR1B Melatonin receptor 1B GPCR P49286
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT332 AOC3 Amine oxidase, copper containing Oxidoreductase Q16853
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT340 GLRA1 Glycine receptor subunit alpha-1 Ion channel P23415
TCMT38 DRD2 Dopamine D2 receptor GPCR P14416
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT555 HDAC6 Histone deacetylase 6 Hydrolase Q9UBN7
TCMT559 ADRB2 Beta-2 adrenergic receptor GPCR P07550
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT633 SLC6A4 Serotonin transporter Transporter P31645
TCMT634 SLC6A2 Norepinephrine transporter Transporter P23975
TCMT635 SLC6A3 Dopamine transporter Transporter Q01959
TCMT636 POLA1 DNA polymerase alpha subunit Transferase P09884
TCMT648 DRD4 Dopamine D4 receptor GPCR P21917
TCMT651 DRD3 Dopamine D3 receptor GPCR P35462
TCMT653 GRM1 Metabotropic glutamate receptor 1 GPCR Q13255
TCMT654 GRM5 Metabotropic glutamate receptor 5 GPCR P41594
TCMT655 GRM2 Metabotropic glutamate receptor 2 GPCR Q14416
TCMT656 GRM3 Metabotropic glutamate receptor 3 GPCR Q14832
TCMT657 GRM4 Metabotropic glutamate receptor 4 GPCR Q14833
TCMT660 GRM8 Metabotropic glutamate receptor 8 GPCR O00222
TCMT661 FOLH1 Glutamate carboxypeptidase II Hydrolase Q04609
TCMT664 SLC1A1 Excitatory amino acid transporter 3 Transporter P43005
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1121 Sialidase
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1207 Legionella pneumophila
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1294 Human parainfluenza virus 3
TCMT1412 Salmonella typhimurium
TCMT1454 Bacillus subtilis
TCMT1458 Filobasidiella neoformans
TCMT1463 Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC902
Formula: C27H46O

Ingredient ID: TCMC734
Formula: C4H7NO4

Ingredient ID: TCMC721
Formula: C6H14N4O2

Ingredient ID: TCMC2594
Formula: C6H13NO2

Ingredient ID: TCMC2502
Formula: C23H22O6

Ingredient ID: TCMC2421
Formula: C28H46O

Ingredient ID: TCMC2408
Formula: C5H11NO2

Ingredient ID: TCMC2200
Formula: C9H11NO3

Ingredient ID: TCMC2107
Formula: C29H48O

Ingredient ID: TCMC209
Formula: C4H6N4O3

Ingredient ID: TCMC2062
Formula: C3H7NO3

Ingredient ID: TCMC1905
Formula: C16H19NO3

Ingredient ID: TCMC1848
Formula: C14H25NO

Ingredient ID: TCMC1513
Formula: C5H9NO2

Ingredient ID: TCMC1512
Formula: C9H11NO2

Ingredient ID: TCMC1480
Formula: C5H9NO4

Ingredient ID: TCMC1459
Formula: C3H7NO2

Ingredient ID: TCMC1331
Formula: C6H9N3O2

Ingredient ID: TCMC1271
Formula: C2H5NO2

Ingredient ID: TCMC1228
Formula: C24H28O7

Ingredient ID: TCMC1209
Formula: C4H9NO2

Ingredient ID: TCMC1122
Formula: C28H44O

Ingredient ID: TCMC1083
Formula: C8H11NO2

Ingredient ID: TCMC1072
Formula: C27H42O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC209 C4H6N4O3 [(4S)-2,5-Dioxoimidazolidin-4-Yl]Urea 158.04 -0.2279 1.13 -0.469 7 5 121.29 5 1 11 0
TCMC721 C6H14N4O2 Arginine 174.11 -2.1807 1.46 -2.924 6 5 125.22 9 0 12 0
TCMC734 C4H7NO4 Aspartic Acid 133.04 -1.3518 1.35 -3.707 5 3 100.62 6 0 9 0
TCMC902 C27H46O Cholesterol 386.35 1.5548 4.32 10.518 1 1 20.23 11 4 28 1
TCMC1072 C27H42O3 Disogenin 414.31 0.2771 4.1 6.041 3 1 38.69 5 6 30 1
TCMC1083 C8H11NO2 Dopamine 153.08 -1.4033 2.01 0.57 1 3 66.48 5 1 11 0
TCMC1122 C28H44O Ergosterol 396.34 2.2555 4.43 9.499 1 1 20.23 11 4 29 1
TCMC1209 C4H9NO2 Gamma-Aminobutyric Acid 103.06 -1.2313 1.57 -0.668 3 2 63.32 5 0 7 0
TCMC1228 C24H28O7 Garcinone D 428.18 0.4786 3.33 2.213 2 4 116.45 15 3 31 0
TCMC1271 C2H5NO2 Glycine 75.03 -1.1915 1.35 -3.35 3 2 63.32 3 0 5 0
TCMC1331 C6H9N3O2 Histidine 155.07 -1.3116 1.57 -3.134 5 3 92 5 1 11 0
TCMC1459 C3H7NO2 L-Alanine 89.05 -1.0955 1.46 -2.824 3 2 63.32 4 0 6 0
TCMC1480 C5H9NO4 L-Glutamate 147.05 -1.6398 1.46 -3.349 5 3 100.62 7 0 10 0
TCMC1512 C9H11NO2 L-Phenylalanine 165.08 -1.0844 2.12 0.441 3 2 63.32 5 1 12 0
TCMC1513 C5H9NO2 L-Proline 115.06 -1.3817 1.68 -0.185 3 2 49.33 2 1 8 0
TCMC1848 C14H25NO Pellitorin 223.19 0.5505 2.78 4.887 2 1 32.59 12 0 16 0
TCMC1905 C16H19NO3 Piperlonguminine 273.14 0.8049 2.78 3.657 2 1 51.05 8 2 20 0
TCMC2062 C3H7NO3 Serine 105.04 -1.5955 1.35 -3.956 4 3 83.55 5 0 7 0
TCMC2107 C29H48O Stigmasterol 412.37 1.2566 4.54 11.071 1 1 20.23 12 4 30 1
TCMC2200 C9H11NO3 Tyrosine 181.07 -1.5447 2.01 -1.577 3 3 83.55 6 1 13 0
TCMC2408 C5H11NO2 Valine 117.08 -0.5739 1.68 -2.169 3 2 63.32 6 0 8 0
TCMC2421 C28H46O 3-Beta-Hydroxyergost-5,24(28)-Diene 398.35 2.1615 4.43 10.105 1 1 20.23 11 4 29 1
TCMC2502 C23H22O6 Garcinone B 394.14 0.9864 3.33 2.521 1 3 96.22 9 4 29 0
TCMC2594 C6H13NO2 Leucine 131.09 -0.3183 1.79 -1.389 3 2 63.32 7 0 9 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)