Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1480	TCMT107	Glutamate receptor ionotropic kainate 2	Homo sapiens	Ki: 1106 (nM), Ref: 10821708
TCMC1480	TCMT108	Glutamate receptor ionotropic, AMPA 1	Homo sapiens	Ki: 1360 (nM), Ref: 9357531
TCMC1480	TCMT109	Glutamate receptor ionotropic, AMPA 2	Homo sapiens	Ki: 940 (nM), Ref: 9357531
TCMC1480	TCMT110	Glutamate receptor ionotropic, AMPA 4	Homo sapiens	Ki: 868 (nM), Ref: 9357531
TCMC1480	TCMT111	Glutamate receptor ionotropic kainate 5	Homo sapiens	Ki: 701 (nM), Ref: 9357531
TCMC1480	TCMT660	Metabotropic glutamate receptor 8	Homo sapiens	IC50: 5.7 (nM), Ref: 15603952
TCMC1480	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 613 (nM), Ref: 16250647
TCMC1480	TCMT653	Metabotropic glutamate receptor 1	Homo sapiens	Ki: 250 (nM), Ref: 17725337 Ki: 570 (nM), Ref: 19042134 Ki: 1584.89 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT654	Metabotropic glutamate receptor 5	Homo sapiens	Ki: 390 (nM), Ref: 17725337 Ki: 1160 (nM), Ref: 19042134 Ki: 4677.35 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT657	Metabotropic glutamate receptor 4	Homo sapiens	Ki: 2400 (nM), Ref: 17725337 Ki: 1400 (nM), Ref: 19042134 Ki: 3235.94 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT655	Metabotropic glutamate receptor 2	Homo sapiens	Ki: 6400 (nM), Ref: 19042134 Ki: 1819.7 (nM), Ref: 10.1039/C1MD00186H
TCMC1480	TCMT664	Excitatory amino acid transporter 3	Homo sapiens	Ki: 51 (nM), Ref: 18578477
TCMC1480	TCMT656	Metabotropic glutamate receptor 3	Homo sapiens	Ki: 57.54 (nM), Ref: 10.1039/C1MD00186H
TCMC1083	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 1.89 (nM), Ref: 10465538 Ki: 759 (nM), Ref: 10465538 Ki: 572 (nM), Ref: 8893836 Ki: 20 (nM), Ref: 10691700 Ki: 17 (nM), Ref: 10691700 Ki: 450 (nM), Ref: 18834111 Ki: 360 (nM), Ref: 18834111 Ki: 2100 (nM), Ref: 20155917 Ki: 2.9 (nM), Ref: 20155917 Ki: 2100 (nM), Ref: 22846798 Ki: 422 (nM), Ref: 23134120 Ki: 110 (nM), Ref: 23428965 Ki: 190 (nM), Ref: 23428965 Ki: 2100 (nM), Ref: 23727194 Ki: 8 (nM), Ref: 24138311 Ki: 8.73 (nM), Ref: 27035329 Ki: 3690 (nM), Ref: 27035329 Ki: 48 (nM), Ref: 27132867
TCMC1083	TCMT651	Dopamine D3 receptor	Homo sapiens	Ki: 13.2 (nM), Ref: 8893836 Ki: 50 (nM), Ref: 10691700 Ki: 240 (nM), Ref: 18834111 Ki: 72 (nM), Ref: 18834111 Ki: 15 (nM), Ref: 22846798 Ki: 20 (nM), Ref: 23134120 Ki: 21 (nM), Ref: 23428965 Ki: 15 (nM), Ref: 23727194 Ki: 7.58 (nM), Ref: 27035329 Ki: 293 (nM), Ref: 27035329
TCMC1083	TCMT635	Dopamine transporter	Homo sapiens	Ki: 6400 (nM), Ref: 14592523 IC50: 460 (nM), Ref: 14592523
TCMC1083	TCMT634	Norepinephrine transporter	Homo sapiens	IC50: 6.63 (nM), Ref: 14592523
TCMC1083	TCMT648	Dopamine D4 receptor	Homo sapiens	Ki: 1.2 (nM), Ref: 10691700 Ki: 6.2 (nM), Ref: 18834111 Ki: 8.9 (nM), Ref: 23428965
TCMC1083	TCMT316	Melatonin receptor 1A	Homo sapiens	Ki: 7100 (nM), Ref: 10.1016/S0960-894X(97)00444-7
TCMC1083	TCMT317	Melatonin receptor 1B	Homo sapiens	Ki: 9100 (nM), Ref: 10.1016/S0960-894X(97)00444-7
TCMC1083	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 4470 (nM), Ref: 23134120
TCMC1083	TCMT8	Lysine-specific demethylase 4D-like	Homo sapiens	IC50: 3000 (nM), Ref: 10.1039/C1MD00199J
TCMC1228	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 5200 (nM), Ref: 18558747

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC1848	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 50 (ug/ml), Ref: 22280816