Description of the Component
Component ID |
TCMH232 |
Latin Name |
Bufo melanostictus |
English Name |
Toad |
Chinese Pinyin Name |
Chan Chu |
中文名 |
蟾蜍 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Classical Prescriptions |
Barcode ID |
GBAP778-09 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF2515 | Plus and Minus DH Decoction | 加减地黄汤 |
| TCMF3547 | Fu Fang Ge Qing Zhu She Oral Liquid | 复方蛤青注射液 |
| TCMF3957 | Chan Long Ding Chuan Recipe | 蟾龙定喘合剂 |
| TCMFx4649 | Ji De Sheng She Yao Tablets | 季德胜蛇药片 |
| TCMFx6821 | Zhan Jiang Chan Chu Ointment | 湛江蟾蜍膏 |
Showing 1 to 5 of 5 entries
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
| TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT241 | CHRNA7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Ion channel | P36544 |
Showing 1 to 10 of 35 entries
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1086 | Isocitrate lyase |
| TCMT1353 | Plasmodium yoelii |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1463 | Mycobacterium tuberculosis |
Showing 1 to 5 of 5 entries
Ingredient Structrues
Ingredient ID: TCMC831
Formula: C24H32O4
Ingredient ID: TCMC831
| Common Name | Bufogenin |
| IUPAC Name | n.a. |
| Canonical SMILES | O[C@H]1CC[C@]2([C@@H](C1)CC[C@@H]1[C@@H]2CC[C@]2([C@]31O[C@@H]3C[C@@H]2c1ccc(=O)oc1)C)C |
| Standard InCHI | InChI=1S/C24H32O4/c1-22-9-7-16(25)11-15(22)4-5-18-17(22)8-10-23(2)19(12-20-24(18,23)28-20)14-3-6-21(26)27-13-14/h3,6,13,15-20,25H,4-5,7-12H2,1-2H3/t15-,16+,17+,18-,19-,20-,22+,23-,24-/m1/s1 |
| Standard InCHIKey | ATLJNLYIJOCWJE-CWMZOUAVSA-N |
| External Identifiers | ChEMBL [CHEMBL250172]; PubChem [6917974]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
Ingredient ID: TCMC2196
Formula: C15H8N2O2
Ingredient ID: TCMC2196
| Common Name | Tryptanthrin |
| IUPAC Name | indolo[2,1-b]quinazoline-6,12-dione |
| Canonical SMILES | O=C1c2nc3ccccc3c(=O)n2c2c1cccc2 |
| Standard InCHI | InChI=1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H |
| Standard InCHIKey | VQQVWGVXDIPORV-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL306946]; PubChem [73549]; |
| Reference of Component-Ingredient Pair | 11937358 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH126 | Isatis indigotica | Ban Lan | 板蓝 |
| TCMH127 | Isatis indigotica | Ban Lan Gen | 板蓝根 |
| TCMH1281 | Folium polygoni tinctorii | Liao Da Qing Ye | 蓼大青叶 |
| TCMH1430 | Hordeum vulgare | Mai Ya | 麦芽 |
| TCMH1510 | Isatis indigotica | Mu Ban Lan Gen | 木板蓝根 |
| TCMH1512 | Isatis indigotica | Mu Da Qing Ye | 木大青叶 |
| TCMH1537 | Baphicacanthus cusia | Nan Ban Lan Gen | 南板蓝根 |
| TCMH1538 | Baphicacanthus cusia | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 |
| TCMH1678 | Indigo naturalis | Qing Dai | 青黛 |
| TCMH232 | Bufo melanostictus | Chan Chu | 蟾蜍 |
Showing 1 to 10 of 13 entries
Ingredient ID: TCMC2063
Formula: C10H12N2O
Ingredient ID: TCMC2063
| Common Name | Serotonin |
| IUPAC Name | 3-(2-aminoethyl)-1H-indol-5-ol |
| Canonical SMILES | NCCc1c[nH]c2c1cc(O)cc2 |
| Standard InCHI | InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 |
| Standard InCHIKey | QZAYGJVTTNCVMB-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL39]; PubChem [5202]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1734 | Homo sapiens | Ren Zhong Bai | 人中白 |
| TCMH232 | Bufo melanostictus | Chan Chu | 蟾蜍 |
| TCMH2710 | Homo sapiens | Zi He Che | 紫河车 |
| TCMH363 | Rheum officinale | Da Huang | 大黄 |
| TCMH365 | Rheum officinale | Da Huang Jin Gao | 大黄浸膏 |
| TCMH366 | Rheum officinale | Da Huang Liu Jin Gao | 大黄流浸膏 |
| TCMH641 | Bufo melanostictus | Gan Chan | 干蟾 |
Showing 1 to 7 of 7 entries
Ingredient ID: TCMC1997
Formula: C9H13NO3
Ingredient ID: TCMC1997
| Common Name | Racepinephrine |
| IUPAC Name | 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol |
| Canonical SMILES | CNCC(c1ccc(c(c1)O)O)O |
| Standard InCHI | InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 |
| Standard InCHIKey | UCTWMZQNUQWSLP-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL1740]; PubChem [838]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1575 | Bubalus bubalis | Niu Jiao Fen | 牛角粉 |
| TCMH1576 | Bubalus bubalis | Niu Jiao Jian Fen | 牛角尖粉 |
| TCMH1577 | Bubalus bubalis | Niu Jiao Tan | 牛角炭 |
| TCMH1734 | Homo sapiens | Ren Zhong Bai | 人中白 |
| TCMH1997 | Bubalus bubalis | Shui Niu Jiao | 水牛角 |
| TCMH1998 | Bubalus bubalis | Shui Niu Jiao Gan Jin Gao | 水牛角干浸膏 |
| TCMH1999 | Bubalus bubalis | Shui Niu Jiao Nong Suo Fen | 水牛角浓缩粉 |
| TCMH232 | Bufo melanostictus | Chan Chu | 蟾蜍 |
| TCMH2710 | Homo sapiens | Zi He Che | 紫河车 |
| TCMH641 | Bufo melanostictus | Gan Chan | 干蟾 |
Showing 1 to 10 of 10 entries
Ingredient ID: TCMC153
Formula: C15H12O4
Ingredient ID: TCMC153
| Common Name | (E)-3-(2,4-Dihydroxyphenyl)-1-(4-Hydroxyphenyl)Prop-2-En-1-One |
| IUPAC Name | (E)-3-(2,4-dihydroxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
| Canonical SMILES | Oc1ccc(cc1)C(=O)/C=C/c1ccc(cc1O)O |
| Standard InCHI | InChI=1S/C15H12O4/c16-12-5-1-10(2-6-12)14(18)8-4-11-3-7-13(17)9-15(11)19/h1-9,16-17,19H/b8-4+ |
| Standard InCHIKey | VDYSHUXENHRSOO-XBXARRHUSA-N |
| External Identifiers | ChEMBL [CHEMBL3335591]; PubChem [5322052]; |
| Reference of Component-Ingredient Pair | US9549908 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1475 | Glycyrrhiza uralensis | Mi Gan Cao | 蜜甘草 |
| TCMH1899 | Glycyrrhiza uralensis | Sheng Gan Cao | 生甘草 |
| TCMH2135 | Glycyrrhiza uralensis | Tu Gan Cao | 土甘草 |
| TCMH232 | Bufo melanostictus | Chan Chu | 蟾蜍 |
| TCMH628 | Glycyrrhiza uralensis | Gan Cao | 甘草 |
| TCMH629 | Glycyrrhiza uralensis | Gan Cao Fen | 甘草粉 |
| TCMH630 | Glycyrrhiza uralensis | Gan Cao Gan Gao | 甘草干膏 |
| TCMH631 | Glycyrrhiza uralensis | Gan Cao Gan Gao Fen | 甘草干膏粉 |
| TCMH632 | Glycyrrhiza uralensis | Gan Cao Gan Jin Gao | 甘草干浸膏 |
| TCMH633 | Glycyrrhiza uralensis | Gan Cao Gao | 甘草膏 |
Showing 1 to 10 of 14 entries
Ingredient ID: TCMC1209
Formula: C4H9NO2
Ingredient ID: TCMC1209
| Common Name | Gamma-Aminobutyric Acid |
| IUPAC Name | 4-aminobutanoic acid |
| Canonical SMILES | NCCCC(=O)O |
| Standard InCHI | InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) |
| Standard InCHIKey | BTCSSZJGUNDROE-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL96]; PubChem [119]; |
| Reference of Component-Ingredient Pair | 29968805 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1185 | Lycium chinense | Gou Qi | 枸杞 |
| TCMH1186 | Lycium chinense | Gou Qi Zi | 枸杞子 |
| TCMH126 | Isatis indigotica | Ban Lan | 板蓝 |
| TCMH127 | Isatis indigotica | Ban Lan Gen | 板蓝根 |
| TCMH130 | Pinellia ternata | Ban Xia | 半夏 |
| TCMH131 | Pinellia ternata | Ban Xia Qu | 半夏曲 |
| TCMH1343 | Aloe vera | Lu Hui | 芦荟 |
| TCMH1510 | Isatis indigotica | Mu Ban Lan Gen | 木板蓝根 |
| TCMH1512 | Isatis indigotica | Mu Da Qing Ye | 木大青叶 |
| TCMH1575 | Bubalus bubalis | Niu Jiao Fen | 牛角粉 |
Showing 1 to 10 of 58 entries
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC1209 | C4H9NO2 | Gamma-Aminobutyric Acid | 103.06 | -1.2313 | 1.57 | -0.668 | 3 | 2 | 63.32 | 5 | 0 | 7 | 0 |
| TCMC153 | C15H12O4 | (E)-3-(2,4-Dihydroxyphenyl)-1-(4-Hydroxyphenyl)Prop-2-En-1-One | 256.07 | -1.2836 | 2.67 | 2.124 | 1 | 3 | 77.76 | 6 | 2 | 19 | 0 |
| TCMC1997 | C9H13NO3 | Racepinephrine | 183.09 | -1.7378 | 2.01 | -0.07 | 2 | 4 | 72.72 | 7 | 1 | 13 | 0 |
| TCMC2063 | C10H12N2O | Serotonin | 176.09 | -1.3634 | 2.23 | 0.547 | 2 | 3 | 62.04 | 4 | 2 | 13 | 0 |
| TCMC2196 | C15H8N2O2 | Tryptanthrin | 248.06 | -0.8639 | 2.67 | 3.473 | 4 | 0 | 49.74 | 0 | 4 | 19 | 0 |
| TCMC831 | C24H32O4 | Bufogenin | 384.23 | -0.0971 | 3.66 | 4.113 | 4 | 1 | 59.06 | 4 | 6 | 28 | 0 |
Showing 1 to 6 of 6 entries
Download Data
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