Component: Folium polygoni tinctorii 蓼大青叶


Description of the Component

Component ID
TCMH1281
Latin Name
Folium polygoni tinctorii
English Name
Indigoplant leaf
Chinese Pinyin Name
Liao Da Qing Ye
中文名
蓼大青叶
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
remove toxic heat, and cause subsidence of eruptions by reducing heat in blood
Toxicity
NA
Geo-authentic habitats (道地产区)
Hebei Province,Beijing,Tianjin
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3909 Er Tong Ke Oral Liquid 儿童咳液
TCMFx4719 Jia Wei Gan Mao Pills 加味感冒丸
TCMF5813 Sai Xian Yan Tablets 腮腺炎片
TCMF5153 Shi Yi Qing Wen Pills 时疫清瘟丸
TCMFx5229 Tai He Miao Ling Pills 太和妙灵丸
TCMF6584 Xiao Er Bi Yan Tablets 小儿鼻炎片
TCMFx6762 Xiao Er Ji Jing Powder 小儿急惊散

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1353 Plasmodium yoelii
TCMT1439 Mycobacterium smegmatis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1463 Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC6170
Formula: C22H20O12

Ingredient ID: TCMC2196
Formula: C15H8N2O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC2196 C15H8N2O2 Tryptanthrin 248.06 -0.8639 2.67 3.473 4 0 49.74 0 4 19 0
TCMC6170 C22H20O12 3,5,4'-Trihydroxy-6,7-Methylenedioxyflavone-3-O-Β-D-Glucopyranoside 476.0954761 -3.9072 2.56 -0.123 7 6 175.37 4 5 34 1

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3. Putative Targets  
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