Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
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| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
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TCMT30 | Cyclooxygenase-2 | Homo sapiens |
IC50: 64 (nM), Ref: 22819942 IC50: 64 (nM), Ref: 23146282 |
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TCMT130 | Arachidonate 5-lipoxygenase | Homo sapiens |
IC50: 150 (nM), Ref: 22819942 |
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TCMT336 | Indoleamine 2,3-dioxygenase | Homo sapiens |
IC50: 53.7 (nM), Ref: 24099220 IC50: 7150 (nM), Ref: 24099220 Ki: 4810 (nM), Ref: 24099220 |
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TCMT646 | Serotonin 5a (5-HT5a) receptor | Homo sapiens |
Ki: 126 (nM), Ref: 12825922 IC50: 180 (nM), Ref: 18983139 Ki: 110 (nM), Ref: 18983139 IC50: 184 (nM), Ref: 18588282 Ki: 170 (nM), Ref: 21726069 IC50: 280 (nM), Ref: 23582449 Ki: 82 (nM), Ref: 23466604 IC50: 160 (nM), Ref: 23466604 IC50: 180 (nM), Ref: 26988801 |
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TCMT315 | Serotonin 6 (5-HT6) receptor | Homo sapiens |
Ki: 65 (nM), Ref: 12825922 Ki: 100 (nM), Ref: 15357994 IC50: 200 (nM), Ref: 18983139 Ki: 93 (nM), Ref: 18983139 IC50: 262 (nM), Ref: 18588282 IC50: 27.5 (nM), Ref: 20170099 Ki: 84 (nM), Ref: 21726069 Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8 IC50: 180 (nM), Ref: 23582449 Ki: 50 (nM), Ref: 23466604 IC50: 100 (nM), Ref: 23466604 Ki: 33 (nM), Ref: 24805037 Ki: 33 (nM), Ref: 25557493 IC50: 120 (nM), Ref: 26988801 Ki: 100 (nM), Ref: 26996373 |
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TCMT160 | Serotonin 7 (5-HT7) receptor | Homo sapiens |
Ki: 8.1 (nM), Ref: 12825922 IC50: 0.61 (nM), Ref: 18983139 Ki: 0.22 (nM), Ref: 18983139 IC50: 2.55 (nM), Ref: 12713409 IC50: 1.5 (nM), Ref: 18588282 Ki: 0.13 (nM), Ref: 21726069 IC50: 0.49 (nM), Ref: 23582449 Ki: 0.11 (nM), Ref: 23466604 IC50: 0.29 (nM), Ref: 23466604 Ki: 1.4 (nM), Ref: 24763360 Ki: 0.8 (nM), Ref: 24805037 Ki: 0.8 (nM), Ref: 25557493 IC50: 0.25 (nM), Ref: 26988801 |
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TCMT37 | Serotonin 2a (5-HT2a) receptor | Homo sapiens |
Ki: 14 (nM), Ref: 15081042 Ki: 8.2 (nM), Ref: 16392816 Ki: 14 (nM), Ref: 16257207 Ki: 120 (nM), Ref: 18468904 Ki: 160 (nM), Ref: 18468904 Ki: 130 (nM), Ref: 18468904 Ki: 150 (nM), Ref: 18468904 Ki: 320 (nM), Ref: 11975483 Ki: 690 (nM), Ref: 17067154 Ki: 323.59 (nM), Ref: 23301527 Ki: 320 (nM), Ref: 23301527 |
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TCMT313 | Serotonin 2b (5-HT2b) receptor | Homo sapiens |
Ki: 12 (nM), Ref: 15081042 Ki: 13 (nM), Ref: 12954071 Ki: 13 (nM), Ref: 16392816 Ki: 12 (nM), Ref: 16257207 Ki: 13.49 (nM), Ref: 24582985 |
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TCMT314 | Serotonin 2c (5-HT2c) receptor | Homo sapiens |
Ki: 6.9 (nM), Ref: 15081042 Ki: 8.3 (nM), Ref: 12954071 Ki: 8.3 (nM), Ref: 16392816 Ki: 6.9 (nM), Ref: 16257207 Ki: 130 (nM), Ref: 11975483 Ki: 20 (nM), Ref: 17067154 Ki: 79.43 (nM), Ref: 23301527 Ki: 79 (nM), Ref: 23301527 |
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TCMT815 | Serotonin 1d (5-HT1d) receptor | Homo sapiens |
Ki: 5.5 (nM), Ref: 8071931 Ki: 0.5 (nM), Ref: 18507369 |
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TCMT36 | Serotonin 1a (5-HT1a) receptor | Homo sapiens |
Ki: 2.5 (nM), Ref: 7658447 IC50: 1.2 (nM), Ref: 12954071 Ki: 1.259 (nM), Ref: 18433113 Ki: 10000 (nM), Ref: 18433113 Ki: 0.62 (nM), Ref: 22748706 Ki: 0.9 (nM), Ref: 23332346 Ki: 9.5 (nM), Ref: 24161678 Ki: 2.08 (nM), Ref: 25128671 |
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TCMT112 | Adenosine A3 receptor | Homo sapiens |
IC50: 79 (nM), Ref: 16250647 |
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TCMT816 | Serotonin 1b (5-HT1b) receptor | Homo sapiens |
Ki: 1.1 (nM), Ref: 18507369 IC50: 29 (nM), Ref: 18983139 Ki: 18 (nM), Ref: 18983139 Ki: 14 (nM), Ref: 21726069 IC50: 12 (nM), Ref: 23582449 Ki: 4 (nM), Ref: 23466604 IC50: 6.5 (nM), Ref: 23466604 |
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TCMT817 | Serotonin 4 (5-HT4) receptor | Homo sapiens |
Ki: 1049 (nM), Ref: 19334715 Ki: 500 (nM), Ref: 17067154 Ki: 29.51 (nM), Ref: 19223092 Ki: 109.65 (nM), Ref: 19223092 |
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TCMT645 | Serotonin 1e (5-HT1e) receptor | Homo sapiens |
Ki: 10.72 (nM), Ref: 24365159 Ki: 11 (nM), Ref: 24365159 |