Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2196	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 64 (nM), Ref: 22819942 IC50: 64 (nM), Ref: 23146282
TCMC2196	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 150 (nM), Ref: 22819942
TCMC2196	TCMT336	Indoleamine 2,3-dioxygenase	Homo sapiens	IC50: 53.7 (nM), Ref: 24099220 IC50: 7150 (nM), Ref: 24099220 Ki: 4810 (nM), Ref: 24099220
TCMC2063	TCMT646	Serotonin 5a (5-HT5a) receptor	Homo sapiens	Ki: 126 (nM), Ref: 12825922 IC50: 180 (nM), Ref: 18983139 Ki: 110 (nM), Ref: 18983139 IC50: 184 (nM), Ref: 18588282 Ki: 170 (nM), Ref: 21726069 IC50: 280 (nM), Ref: 23582449 Ki: 82 (nM), Ref: 23466604 IC50: 160 (nM), Ref: 23466604 IC50: 180 (nM), Ref: 26988801
TCMC2063	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 65 (nM), Ref: 12825922 Ki: 100 (nM), Ref: 15357994 IC50: 200 (nM), Ref: 18983139 Ki: 93 (nM), Ref: 18983139 IC50: 262 (nM), Ref: 18588282 IC50: 27.5 (nM), Ref: 20170099 Ki: 84 (nM), Ref: 21726069 Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8 IC50: 180 (nM), Ref: 23582449 Ki: 50 (nM), Ref: 23466604 IC50: 100 (nM), Ref: 23466604 Ki: 33 (nM), Ref: 24805037 Ki: 33 (nM), Ref: 25557493 IC50: 120 (nM), Ref: 26988801 Ki: 100 (nM), Ref: 26996373
TCMC2063	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 8.1 (nM), Ref: 12825922 IC50: 0.61 (nM), Ref: 18983139 Ki: 0.22 (nM), Ref: 18983139 IC50: 2.55 (nM), Ref: 12713409 IC50: 1.5 (nM), Ref: 18588282 Ki: 0.13 (nM), Ref: 21726069 IC50: 0.49 (nM), Ref: 23582449 Ki: 0.11 (nM), Ref: 23466604 IC50: 0.29 (nM), Ref: 23466604 Ki: 1.4 (nM), Ref: 24763360 Ki: 0.8 (nM), Ref: 24805037 Ki: 0.8 (nM), Ref: 25557493 IC50: 0.25 (nM), Ref: 26988801
TCMC2063	TCMT37	Serotonin 2a (5-HT2a) receptor	Homo sapiens	Ki: 14 (nM), Ref: 15081042 Ki: 8.2 (nM), Ref: 16392816 Ki: 14 (nM), Ref: 16257207 Ki: 120 (nM), Ref: 18468904 Ki: 160 (nM), Ref: 18468904 Ki: 130 (nM), Ref: 18468904 Ki: 150 (nM), Ref: 18468904 Ki: 320 (nM), Ref: 11975483 Ki: 690 (nM), Ref: 17067154 Ki: 323.59 (nM), Ref: 23301527 Ki: 320 (nM), Ref: 23301527
TCMC2063	TCMT313	Serotonin 2b (5-HT2b) receptor	Homo sapiens	Ki: 12 (nM), Ref: 15081042 Ki: 13 (nM), Ref: 12954071 Ki: 13 (nM), Ref: 16392816 Ki: 12 (nM), Ref: 16257207 Ki: 13.49 (nM), Ref: 24582985
TCMC2063	TCMT314	Serotonin 2c (5-HT2c) receptor	Homo sapiens	Ki: 6.9 (nM), Ref: 15081042 Ki: 8.3 (nM), Ref: 12954071 Ki: 8.3 (nM), Ref: 16392816 Ki: 6.9 (nM), Ref: 16257207 Ki: 130 (nM), Ref: 11975483 Ki: 20 (nM), Ref: 17067154 Ki: 79.43 (nM), Ref: 23301527 Ki: 79 (nM), Ref: 23301527
TCMC2063	TCMT815	Serotonin 1d (5-HT1d) receptor	Homo sapiens	Ki: 5.5 (nM), Ref: 8071931 Ki: 0.5 (nM), Ref: 18507369
TCMC2063	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 2.5 (nM), Ref: 7658447 IC50: 1.2 (nM), Ref: 12954071 Ki: 1.259 (nM), Ref: 18433113 Ki: 10000 (nM), Ref: 18433113 Ki: 0.62 (nM), Ref: 22748706 Ki: 0.9 (nM), Ref: 23332346 Ki: 9.5 (nM), Ref: 24161678 Ki: 2.08 (nM), Ref: 25128671
TCMC2063	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 79 (nM), Ref: 16250647
TCMC2063	TCMT816	Serotonin 1b (5-HT1b) receptor	Homo sapiens	Ki: 1.1 (nM), Ref: 18507369 IC50: 29 (nM), Ref: 18983139 Ki: 18 (nM), Ref: 18983139 Ki: 14 (nM), Ref: 21726069 IC50: 12 (nM), Ref: 23582449 Ki: 4 (nM), Ref: 23466604 IC50: 6.5 (nM), Ref: 23466604
TCMC2063	TCMT817	Serotonin 4 (5-HT4) receptor	Homo sapiens	Ki: 1049 (nM), Ref: 19334715 Ki: 500 (nM), Ref: 17067154 Ki: 29.51 (nM), Ref: 19223092 Ki: 109.65 (nM), Ref: 19223092
TCMC2063	TCMT645	Serotonin 1e (5-HT1e) receptor	Homo sapiens	Ki: 10.72 (nM), Ref: 24365159 Ki: 11 (nM), Ref: 24365159

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2063	TCMT1086	Isocitrate lyase	Candida albicans	IC50: 53 (ug/ml), Ref: 21035332
TCMC2196	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 10 (ug/ml), Ref: 22819942 MIC: 0.5 (ug/ml), Ref: 26253635
TCMC2196	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 1 (ug/ml), Ref: 23360475 MIC: 1 (ug/ml), Ref: 26253635
TCMC2196	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 6 (ug/ml), Ref: 26253635