Component: Linum usitatissimum 亚麻子


Description of the Component

Component ID
TCMH2367
Latin Name
Linum usitatissimum
English Name
Common flax seed
Chinese Pinyin Name
Ya Ma Zi
中文名
亚麻子
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
cause lubrication, and dispel wind
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
PLTOR003-08
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF6030 Xiao Feng Zhi Yang Granules 消风止痒颗粒
TCMF6598 Xun Ma Zhen Pills 荨麻疹丸

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT103 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) Hydrolase P10586
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT175 GPBAR1 G-protein coupled bile acid receptor 1 GPCR Q8TDU6
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT220 CYP2J2 Cytochrome P450 2J2 Oxidoreductase P51589
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT230 HSD17B3 Estradiol 17-beta-dehydrogenase 3 Oxidoreductase P37058
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT233 PTPN11 Protein-tyrosine phosphatase 2C Hydrolase Q06124
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT290 CHRM5 Muscarinic acetylcholine receptor M5 GPCR P08912
TCMT291 CHRM3 Muscarinic acetylcholine receptor M3 GPCR P20309
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT334 EBP 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Isomerase Q15125
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT341 NR1I2 Pregnane X receptor Nuclear receptor O75469
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT613 NR3C1 Glucocorticoid receptor Nuclear receptor P04150
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT632 PNP Purine nucleoside phosphorylase Transferase P00491
TCMT636 POLA1 DNA polymerase alpha subunit Transferase P09884
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT725 CACNA1C Voltage-gated L-type calcium channel alpha-1C subunit Ion channel Q13936
TCMT747 ABCG2 ATP-binding cassette sub-family G member 2 Transporter Q9UNQ0
TCMT783 NR3C2 Mineralocorticoid receptor Nuclear receptor P08235
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT904 PGR Progesterone receptor Nuclear receptor P06401
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1108 Integrase
TCMT1180 Human herpesvirus 2
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1246 Escherichia coli
TCMT1247 Human herpesvirus 1
TCMT1250 Vesicular stomatitis virus
TCMT1251 Candida albicans
TCMT1293 Vaccinia virus
TCMT1294 Human parainfluenza virus 3
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1412 Salmonella typhimurium
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1450 Plasmodium falciparum 3D7
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC948
Formula: C9H8O3

Ingredient ID: TCMC902
Formula: C27H46O

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC694
Formula: C19H26O2

Ingredient ID: TCMC5219
Formula: C55H73N9O9S2

Ingredient ID: TCMC514
Formula: C10H13N5O3

Ingredient ID: TCMC50
Formula: C8H15NO

Ingredient ID: TCMC4532
Formula: C30H50O4

Ingredient ID: TCMC3027
Formula: C10H17NO6

Ingredient ID: TCMC29
Formula: C20H26O6

Ingredient ID: TCMC2694
Formula: C20H24O6

Ingredient ID: TCMC2493
Formula: C20H40O

Ingredient ID: TCMC2457
Formula: C20H22O6

Ingredient ID: TCMC2182
Formula: C20H40O

Ingredient ID: TCMC2142
Formula: C19H28O2

Ingredient ID: TCMC2107
Formula: C29H48O

Ingredient ID: TCMC2105
Formula: C18H36O2

Ingredient ID: TCMC200
Formula: C17H23NO3

Ingredient ID: TCMC1940
Formula: C21H30O2

Ingredient ID: TCMC1919
Formula: C22H22O8

Ingredient ID: TCMC19
Formula: C20H22O6

Ingredient ID: TCMC1899
Formula: C20H22O6

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC182
Formula: C9H8O4

Ingredient ID: TCMC1788
Formula: C18H34O2

Ingredient ID: TCMC1538
Formula: C20H22O6

Ingredient ID: TCMC1496
Formula: C18H30O2

Ingredient ID: TCMC1495
Formula: C18H32O2

Ingredient ID: TCMC1349
Formula: C21H30O3

Ingredient ID: TCMC1340
Formula: C21H30O5

Ingredient ID: TCMC1240
Formula: C20H34O

Ingredient ID: TCMC1173
Formula: C10H10O4

Ingredient ID: TCMC1107
Formula: C17H23NO3

Ingredient ID: TCMC1070
Formula: C21H16O7

Ingredient ID: TCMC1014
Formula: C10H13N5O4

Ingredient ID: TCMC1011
Formula: C10H13N5O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC19 C20H22O6 (-)-Pinoresinol 358.14 -2.0222 3 1.684 2 2 77.38 8 4 26 0
TCMC29 C20H26O6 (+)-Secoisolariciresinol 362.17 -1.8914 3 1.708 2 4 99.38 15 2 26 0
TCMC50 C8H15NO (1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Ol 141.12 -1.648 2.12 0.477 2 1 23.47 2 2 10 0
TCMC182 C9H8O4 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC200 C17H23NO3 [(1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Yl] (2R)-3-Hydroxy-2-Phenylpropanoate 289.17 -1.8722 2.89 3.538 4 1 49.77 7 3 21 0
TCMC514 C10H13N5O3 5-(6-Aminopurin-9-Yl)-2-(Hydroxymethyl)Oxolan-3-Ol 251.1 -2.0564 1.68 -1.208 8 3 119.31 5 3 18 0
TCMC694 C19H26O2 Androstenedione 286.19 0.8312 3.33 3.028 2 0 34.14 2 4 21 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC847 C9H8O4 Caffeic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC902 C27H46O Cholesterol 386.35 1.5548 4.32 10.518 1 1 20.23 11 4 28 1
TCMC948 C9H8O3 Coumaric Acid 164.05 -0.339 2.12 1.886 2 2 57.53 4 1 12 0
TCMC1011 C10H13N5O3 Deoxyadenosine 251.1 -2.0564 1.68 -1.208 8 3 119.31 5 3 18 0
TCMC1014 C10H13N5O4 Deoxyguanosine 267.1 -1.9925 1.57 -1.042 9 5 135.98 5 3 19 0
TCMC1070 C21H16O7 Diphyllin 380.09 -0.9461 3 2.017 2 1 83.45 6 5 28 0
TCMC1107 C17H23NO3 Endo-Atropine 289.17 -1.8722 2.89 3.538 4 1 49.77 7 3 21 0
TCMC1173 C10H10O4 Ferulic Acid 194.06 -0.3908 2.12 1.231 2 2 66.76 6 1 14 0
TCMC1240 C20H34O Geranylgeraniol 290.26 4.8041 3.55 6.168 1 1 20.23 16 0 21 1
TCMC1340 C21H30O5 Hydrocortisone 362.21 -1.1216 3.22 0.553 5 3 94.83 7 4 26 0
TCMC1349 C21H30O3 Hydroxyprogesterone 330.22 0.3167 3.44 3.035 3 1 54.37 5 4 24 0
TCMC1495 C18H32O2 Linoleic Acid 280.24 -0.9485 3.22 7.865 2 1 37.3 16 0 20 2
TCMC1496 C18H30O2 Linolenic Acid 278.22 -0.0979 3.22 7.538 2 1 37.3 15 0 20 2
TCMC1538 C20H22O6 Matairesinol 358.14 -0.9121 3 2.415 2 2 85.22 10 3 26 0
TCMC1788 C18H34O2 Oleic Acid 282.26 -2.3427 3.22 8.192 2 1 37.3 17 0 20 2
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1899 C20H22O6 Pinoresinol 358.14 -2.0222 3 1.684 2 2 77.38 8 4 26 0
TCMC1919 C22H22O8 Podofilox 414.13 -1.5006 3 1.259 3 1 92.68 8 5 30 0
TCMC1940 C21H30O2 Progesterone 314.22 0.9172 3.55 4.826 2 0 34.14 4 4 23 0
TCMC2105 C18H36O2 Stearic Acid 284.27 -4.4737 3.22 8.708 2 1 37.3 18 0 20 2
TCMC2107 C29H48O Stigmasterol 412.37 1.2566 4.54 11.071 1 1 20.23 12 4 30 1
TCMC2142 C19H28O2 Testosterone 288.21 0.2615 3.33 3.635 2 1 37.3 3 4 21 0
TCMC2182 C20H40O Trans-Phytol 296.31 1.7816 3.55 8.949 1 1 20.23 19 0 21 2
TCMC2457 C20H22O6 (+/-)-Pinoresinol 358.14 -2.0222 3 1.684 2 2 77.38 8 4 26 0
TCMC2493 C20H40O 3,7,11,15-Tetramethylhexadec-2-En-1-Ol 296.31 1.7816 3.55 8.949 1 1 20.23 19 0 21 2
TCMC2694 C20H24O6 Isolariciresinol 360.16 -2.2141 3 1.061 2 4 99.38 11 3 26 0
TCMC3027 C10H17NO6 Linamarin 247.1055873 -1.5784 1.79 -1.478 7 4 123.17 3 1 17 0
TCMC4532 C30H50O4 Eicosyl Ferulate 474.3709101 -5.3632 4.32 12.006 2 1 55.76 23 1 34 2
TCMC5219 C55H73N9O9S2 Cyclolinopeptide I 1067.497267 -6.0102 5.31 11.209 18 8 301.38 15 6 75 4

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