Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC948	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 6680 (nM), Ref: 20185318 Ki: 6680 (nM), Ref: 26498394
TCMC948	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8010 (nM), Ref: 20185318 Ki: 8010 (nM), Ref: 26498394
TCMC948	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 5330 (nM), Ref: 20185318
TCMC948	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 5230 (nM), Ref: 20185318
TCMC948	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6720 (nM), Ref: 20185318
TCMC948	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 7760 (nM), Ref: 20185318
TCMC948	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5960 (nM), Ref: 20185318
TCMC948	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9600 (nM), Ref: 20185318
TCMC948	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7570 (nM), Ref: 20185318
TCMC948	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 980 (nM), Ref: 20185318
TCMC948	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1070 (nM), Ref: 20185318
TCMC948	TCMT223	Aldose reductase	Homo sapiens	IC50: 140 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1107	TCMT290	Muscarinic acetylcholine receptor M5	Homo sapiens	Ki: 0.14 (nM), Ref: 23707254 Ki: 0.3388 (nM), Ref: 24365159 Ki: 0.34 (nM), Ref: 24365159 Ki: 3.02 (nM), Ref: 25051097
TCMC1107	TCMT291	Muscarinic acetylcholine receptor M3	Homo sapiens	Ki: 0.2692 (nM), Ref: 24365159 Ki: 0.27 (nM), Ref: 24365159
TCMC1107	TCMT292	Muscarinic acetylcholine receptor M1	Homo sapiens	Ki: 0.2692 (nM), Ref: 24365159 Ki: 0.27 (nM), Ref: 24365159
TCMC1107	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 5.012 (nM), Ref: 25051097 Ki: 12.88 (nM), Ref: 25051097 Ki: 3.631 (nM), Ref: 25051097 Ki: 2.818 (nM), Ref: 25051097
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC694	TCMT230	Estradiol 17-beta-dehydrogenase 3	Homo sapiens	IC50: 758 (nM), Ref: 11086723 IC50: 758 (nM), Ref: 16078844
TCMC694	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 20 (nM), Ref: 8035427 Ki: 35 (nM), Ref: 26469743
TCMC2142	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 600 (nM), Ref: 6827528
TCMC2142	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 10000 (nM), Ref: 14552748
TCMC2142	TCMT187	Androgen Receptor	Homo sapiens	IC50: 3.9 (nM), Ref: 15456242 IC50: 2.7 (nM), Ref: 16309907 IC50: 4.571 (nM), Ref: 22746350 IC50: 4.17 (nM), Ref: 25646649 IC50: 4.27 (nM), Ref: 25646649
TCMC2142	TCMT99	Testis-specific androgen-binding protein	Homo sapiens	IC50: 14 (nM), Ref: 17149875
TCMC2142	TCMT725	Voltage-gated L-type calcium channel alpha-1C subunit	Homo sapiens	IC50: 34 (nM), Ref: 22761000 IC50: 38.4 (nM), Ref: 22761000
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1919	TCMT613	Glucocorticoid receptor	Homo sapiens	IC50: 14 (nM), Ref: 19364854
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC1940	TCMT187	Androgen Receptor	Homo sapiens	Ki: 8.5 (nM), Ref: 12954062 IC50: 37 (nM), Ref: 12954062 IC50: 37 (nM), Ref: 12781197 IC50: 37 (nM), Ref: 8627601 Ki: 8.5 (nM), Ref: 8627601 Ki: 8.5 (nM), Ref: 9873735 IC50: 37 (nM), Ref: 9784110 Ki: 35 (nM), Ref: 20510622
TCMC1940	TCMT613	Glucocorticoid receptor	Homo sapiens	Ki: 30.5 (nM), Ref: 12954062 Ki: 30.5 (nM), Ref: 9873735 Ki: 30.5 (nM), Ref: 9784110
TCMC1940	TCMT783	Mineralocorticoid receptor	Homo sapiens	IC50: 14 (nM), Ref: 12954062 IC50: 14 (nM), Ref: 12781197 IC50: 14 (nM), Ref: 9784110 IC50: 30 (nM), Ref: 8709117
TCMC1940	TCMT904	Progesterone receptor	Homo sapiens	Ki: 3.5 (nM), Ref: 10212133 IC50: 3.5 (nM), Ref: 11859003 Ki: 3.5 (nM), Ref: 9464361 IC50: 5 (nM), Ref: 8523399 Ki: 3.8 (nM), Ref: 9667968 Ki: 3.467 (nM), Ref: 16821785 Ki: 3.4 (nM), Ref: 18553958 Ki: 5.1 (nM), Ref: 20510622

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC2493	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20004575 MIC: 1.56 (ug/ml), Ref: 22280816
TCMC1011	TCMT1180	Human herpesvirus 2	Human herpesvirus 2	MIC: 100 (ug/ml), Ref: 1335077
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2182	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1919	TCMT1247	Human herpesvirus 1	Human herpesvirus 1	MIC: 10 (nM), Ref: 11311065 IC50: 50 (nM), Ref: 9834179
TCMC1919	TCMT1180	Human herpesvirus 2	Human herpesvirus 2	MIC: 10 (nM), Ref: 11311065
TCMC1919	TCMT1250	Vesicular stomatitis virus	Vesicular stomatitis virus	IC50: 100 (nM), Ref: 9834179