Description of the Component
Component ID |
TCMH2703 |
Latin Name |
Fritillaria unibracteata |
English Name |
NA |
Chinese Pinyin Name |
Zi Bei Mu |
中文名 |
ç´«è´æ¯ |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
CFDA |
Barcode ID |
ITSAM1616-14 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF4007 | Gui Jia Yang Yin Tablets | 龟甲养阴片 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT151 | PRKCA | Protein kinase C alpha | Kinase | P17252 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT195 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | Kinase | Q02750 |
| TCMT265 | GSK3B | Glycogen synthase kinase-3 beta | Kinase | P49841 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT307 | KCNH2 | HERG | Ion channel | Q12809 |
| TCMT320 | MMP3 | Matrix metalloproteinase 3 | Hydrolase | P08254 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
| TCMT466 | MAPK9 | c-Jun N-terminal kinase 2 | Kinase | P45984 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT507 | MAPK14 | MAP kinase p38 alpha | Kinase | Q16539 |
| TCMT571 | ADORA2B | Adenosine A2b receptor | GPCR | P29275 |
| TCMT592 | XDH | Xanthine dehydrogenase | Oxidoreductase | P47989 |
| TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
| TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
| TCMT620 | HSPA8 | Heat shock cognate 71 kDa protein | Unclassified | P11142 |
| TCMT624 | HSP90AB1 | Heat shock protein HSP 90-beta | Unclassified | P08238 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
| TCMT632 | PNP | Purine nucleoside phosphorylase | Transferase | P00491 |
| TCMT64 | PPARD | Peroxisome proliferator-activated receptor delta | Nuclear receptor | Q03181 |
| TCMT67 | PPARG | Peroxisome proliferator-activated receptor gamma | Nuclear receptor | P37231 |
| TCMT704 | ERBB2 | Receptor protein-tyrosine kinase erbB-2 | Kinase | P04626 |
| TCMT707 | ADORA2A | Adenosine A2a receptor | GPCR | P29274 |
| TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
| TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1180 | Human herpesvirus 2 |
| TCMT1293 | Vaccinia virus |
| TCMT1438 | Plasmodium falciparum |
Ingredient Structrues
Ingredient ID: TCMC978
Formula: C9H13N3O5
Ingredient ID: TCMC632
Formula: C10H13N5O4
Ingredient ID: TCMC631
Formula: C5H5N5
Ingredient ID: TCMC2209
Formula: C9H12N2O6
Ingredient ID: TCMC2165
Formula: C10H14N2O5
Ingredient ID: TCMC2105
Formula: C18H36O2
Ingredient ID: TCMC1373
Formula: C10H12N4O5
Ingredient ID: TCMC1358
Formula: C5H4N4O
Ingredient ID: TCMC1298
Formula: C10H13N5O5
Ingredient ID: TCMC1297
Formula: C5H5N5O
Ingredient ID: TCMC1011
Formula: C10H13N5O3
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC631 | C5H5N5 | Adenine | 135.05 | -1.1703 | 1.46 | -0.664 | 5 | 2 | 80.48 | 1 | 2 | 10 | 0 |
| TCMC632 | C10H13N5O4 | Adenosine | 267.1 | -2.2791 | 1.57 | -1.809 | 9 | 4 | 139.54 | 6 | 3 | 19 | 0 |
| TCMC978 | C9H13N3O5 | Cytidine | 243.09 | -2.3883 | 1.57 | -0.606 | 8 | 5 | 129.6 | 6 | 2 | 17 | 0 |
| TCMC1011 | C10H13N5O3 | Deoxyadenosine | 251.1 | -2.0564 | 1.68 | -1.208 | 8 | 3 | 119.31 | 5 | 3 | 18 | 0 |
| TCMC1297 | C5H5N5O | Guanine | 151.05 | -1.1064 | 1.35 | -0.498 | 6 | 4 | 97.15 | 1 | 2 | 11 | 0 |
| TCMC1298 | C10H13N5O5 | Guanosine | 283.09 | -2.2152 | 1.46 | -1.643 | 10 | 6 | 156.21 | 6 | 3 | 20 | 1 |
| TCMC1358 | C5H4N4O | Hypoxanthine | 136.04 | -0.8807 | 1.46 | -0.597 | 4 | 2 | 74.69 | 1 | 2 | 10 | 0 |
| TCMC1373 | C10H12N4O5 | Inosine | 268.08 | -1.9895 | 1.57 | -1.742 | 8 | 4 | 133.75 | 6 | 3 | 19 | 0 |
| TCMC2105 | C18H36O2 | Stearic Acid | 284.27 | -4.4737 | 3.22 | 8.708 | 2 | 1 | 37.3 | 18 | 0 | 20 | 2 |
| TCMC2165 | C10H14N2O5 | Thymidine | 242.09 | -1.7707 | 1.79 | -1 | 7 | 3 | 102.59 | 6 | 2 | 17 | 0 |
| TCMC2209 | C9H12N2O6 | Uridine | 244.07 | -2.5465 | 1.57 | -1.782 | 8 | 4 | 122.82 | 6 | 2 | 17 | 0 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
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