Component ID |
TCMH2293 |
Latin Name |
Phaseolus vulgaris |
English Name |
Black turtle bean |
Chinese Pinyin Name |
Xiao Hei Dou |
中文名 |
小黑豆 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
CFDA |
Barcode ID |
ITSAA4763-14 |
Barcode Source |
BOLDSYSTEMS |
Prescription ID | Prescription English Name | Prescription Chinese Name |
---|---|---|
TCMF2878 | Qing Gan Zhi Lin Decoction | 清肝止淋汤 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT175 | GPBAR1 | G-protein coupled bile acid receptor 1 | GPCR | Q8TDU6 |
TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT213 | SLC22A1 | Solute carrier family 22 member 1 | Transporter | O15245 |
TCMT218 | CYP2B6 | Cytochrome P450 2B6 | Oxidoreductase | P20813 |
TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
TCMT348 | SULT1A1 | Sulfotransferase 1A1 | Transferase | P50225 |
TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
TCMT571 | ADORA2B | Adenosine A2b receptor | GPCR | P29275 |
TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
TCMT620 | HSPA8 | Heat shock cognate 71 kDa protein | Unclassified | P11142 |
TCMT632 | PNP | Purine nucleoside phosphorylase | Transferase | P00491 |
TCMT65 | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | Oxidoreductase | P14061 |
TCMT704 | ERBB2 | Receptor protein-tyrosine kinase erbB-2 | Kinase | P04626 |
TCMT707 | ADORA2A | Adenosine A2a receptor | GPCR | P29274 |
TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
TCMT725 | CACNA1C | Voltage-gated L-type calcium channel alpha-1C subunit | Ion channel | Q13936 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
TCMT974 | GPER1 | G-protein coupled estrogen receptor 1 | GPCR | Q99527 |
TCMT99 | SHBG | Testis-specific androgen-binding protein | Unclassified | P04278 |
Target ID | Target Name |
---|---|
TCMT1121 | Sialidase |
TCMT1218 | Staphylococcus aureus |
TCMT1438 | Plasmodium falciparum |
TCMT1439 | Mycobacterium smegmatis |
TCMT1454 | Bacillus subtilis |
Ingredient ID: TCMC632
Formula: C10H13N5O4
Ingredient ID: TCMC2673
Formula: C20H20O4
Ingredient ID: TCMC2278
Formula: C20H18O4
Ingredient ID: TCMC1864
Formula: C15H14O4
Ingredient ID: TCMC1555
Formula: C10H12O4
Ingredient ID: TCMC1136
Formula: C18H22O2
Ingredient ID: TCMC1133
Formula: C18H24O2
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC632 | C10H13N5O4 | Adenosine | 267.1 | -2.2791 | 1.57 | -1.809 | 9 | 4 | 139.54 | 6 | 3 | 19 | 0 |
TCMC1133 | C18H24O2 | Estradiol | 272.18 | -0.4699 | 3.22 | 4.646 | 1 | 2 | 40.46 | 3 | 4 | 20 | 0 |
TCMC1136 | C18H22O2 | Estrone | 270.16 | 0.0998 | 3.22 | 4.039 | 1 | 1 | 37.3 | 2 | 4 | 20 | 0 |
TCMC1555 | C10H12O4 | Methyl 2-Hydroxy-4-Methoxy-6-Methylbenzoate | 196.07 | 0.1411 | 2.12 | 2.253 | 2 | 1 | 55.76 | 7 | 1 | 14 | 0 |
TCMC1864 | C15H14O4 | Peucedanin | 258.09 | 0.637 | 2.67 | 2.842 | 1 | 0 | 48.67 | 5 | 3 | 19 | 0 |
TCMC2278 | C20H18O4 | Phaseolin | 322.12 | -0.2056 | 3.22 | 3.195 | 0 | 1 | 47.92 | 3 | 5 | 24 | 0 |
TCMC2673 | C20H20O4 | Phaseollinisoflavan | 324.14 | -0.1402 | 3.22 | 3.207 | 0 | 2 | 58.92 | 5 | 4 | 24 | 0 |