TCM-ID Component

Description of the Component

Component ID	TCMH2057
Latin Name	Human placenta
English Name	Fetus powder
Chinese Pinyin Name	Tai Pan Fen
中文名	胎盘粉
TCM Properties	Warm,Sweet,Salty
TCM Meridians	Lung,Heart,Kidney
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx1760	Blood Producing Pills	生血片

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT150	RORC	Nuclear receptor ROR-gamma	Nuclear receptor	P51449
TCMT162	UGT1A1	UDP-glucuronosyltransferase 1-1	Transferase	P22309
TCMT175	GPBAR1	G-protein coupled bile acid receptor 1	GPCR	Q8TDU6
TCMT187	AR	Androgen Receptor	Nuclear receptor	P10275
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636
TCMT213	SLC22A1	Solute carrier family 22 member 1	Transporter	O15245
TCMT218	CYP2B6	Cytochrome P450 2B6	Oxidoreductase	P20813
TCMT236	ESR2	Estrogen receptor beta	Nuclear receptor	Q92731
TCMT248	CXCL8	Interleukin-8	Unclassified	P10145
TCMT276	SLCO2B1	Solute carrier organic anion transporter family member 2B1	Transporter	O94956
TCMT277	SLCO1B3	Solute carrier organic anion transporter family member 1B3	Transporter	Q9NPD5
TCMT278	SLCO1B1	Solute carrier organic anion transporter family member 1B1	Transporter	Q9Y6L6
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT344	AOX1	Aldehyde oxidase	Oxidoreductase	Q06278
TCMT348	SULT1A1	Sulfotransferase 1A1	Transferase	P50225
TCMT591	ESRRA	Estrogen-related receptor alpha	Nuclear receptor	P11474
TCMT725	CACNA1C	Voltage-gated L-type calcium channel alpha-1C subunit	Ion channel	Q13936
TCMT82	ESR1	Estrogen receptor alpha	Nuclear receptor	P03372
TCMT910	ESRRB	Estrogen-related receptor beta	Nuclear receptor	O95718
TCMT974	GPER1	G-protein coupled estrogen receptor 1	GPCR	Q99527
TCMT99	SHBG	Testis-specific androgen-binding protein	Unclassified	P04278

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC651
Formula: C18H24O2

Common Name	Alfatradiol
IUPAC Name	(8R,9S,13S,14S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Canonical SMILES	Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@H]2O)C
Standard InCHI	InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1
Standard InCHIKey	VOXZDWNPVJITMN-SFFUCWETSA-N
External Identifiers	ChEMBL [CHEMBL286452]; PubChem [68570];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2058	Human placenta	Tai Pan Zu Zhi Fen	胎盘组织粉
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1880	Moschus moschiferus	She Xiang	麝香
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH1462	Moschus moschiferus	Mao She Xiang	毛麝香
TCMH1463	Moschus moschiferus	Mao She Xiang Jin Gao	毛麝香浸膏
TCMH1717	Moschus moschiferus	Ren Gong She Xiang	人工麝香
TCMH2057	Human placenta	Tai Pan Fen	胎盘粉

Ingredient ID: TCMC39
Formula: C18H22O2

Common Name	(13S)-3-Hydroxy-13-Methyl-7,8,9,11,12,14,15,16-Octahydro-6H-Cyclopenta[A]Phenanthren-17-One
IUPAC Name	(13S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Canonical SMILES	Oc1ccc2c(c1)CCC1C2CC[C@]2(C1CCC2=O)C
Standard InCHI	InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14?,15?,16?,18-/m0/s1
Standard InCHIKey	DNXHEGUUPJUMQT-GUZDXLFXSA-N
External Identifiers	ChEMBL [CHEMBL32152]; PubChem [6710658];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2058	Human placenta	Tai Pan Zu Zhi Fen	胎盘组织粉
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH2050	Punica granatum	Suan Shi Liu	酸石榴
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH1943	Punica granatum	Shi Liu	石榴
TCMH1944	Punica granatum	Shi Liu Pi	石榴皮
TCMH1945	Punica granatum	Shi Liu Zi	石榴子
TCMH2057	Human placenta	Tai Pan Fen	胎盘粉

Ingredient ID: TCMC1133
Formula: C18H24O2

Common Name	Estradiol
IUPAC Name	(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Canonical SMILES	Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2O)C
Standard InCHI	InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
Standard InCHIKey	VOXZDWNPVJITMN-ZBRFXRBCSA-N
External Identifiers	ChEMBL [CHEMBL135]; PubChem [5757];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2058	Human placenta	Tai Pan Zu Zhi Fen	胎盘组织粉
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH700	Drynaria fortunei	Gu Sui Bu	骨碎补
TCMH2293	Phaseolus vulgaris	Xiao Hei Dou	小黑豆
TCMH1153	Vinum	Jiu	酒
TCMH1880	Moschus moschiferus	She Xiang	麝香
TCMH1777	Panax notoginseng	San Qi Ye Jing	三七叶茎
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH1770	Panax notoginseng	San Qi Gan Jin Gao	三七干浸膏
TCMH1771	Panax notoginseng	San Qi Gao Fen	三七膏粉
TCMH1772	Panax notoginseng	San Qi Hua	三七花
TCMH1774	Panax notoginseng	San Qi Jing Ye	三七茎叶
TCMH1776	Panax notoginseng	San Qi Ye	三七叶
TCMH1462	Moschus moschiferus	Mao She Xiang	毛麝香
TCMH1463	Moschus moschiferus	Mao She Xiang Jin Gao	毛麝香浸膏
TCMH1717	Moschus moschiferus	Ren Gong She Xiang	人工麝香
TCMH2057	Human placenta	Tai Pan Fen	胎盘粉

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom
TCMC39	C18H22O2	(13S)-3-Hydroxy-13-Methyl-7,8,9,11,12,14,15,16-Octahydro-6H-Cyclopenta[A]Phenanthren-17-One	270.16	0.0998	3.22	4.039	1	1	37.3	2	4	20
TCMC651	C18H24O2	Alfatradiol	272.18	-0.4699	3.22	4.646	1	2	40.46	3	4	20
TCMC1133	C18H24O2	Estradiol	272.18	-0.4699	3.22	4.646	1	2	40.46	3	4	20

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1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Human placenta 胎盘粉

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC651

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC39

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1133

Occurrence of the ingredient across TCM components

Properties

Download Data