Component: Ricinus communis 蓖麻子


Description of the Component

Component ID
TCMH168
Latin Name
Ricinus communis
English Name
Castorbean seed
Chinese Pinyin Name
Bi Ma Zi
中文名
蓖麻子
TCM Properties
Mild,Pungent,Sweet
TCM Meridians
Lung,Large Intestine
Therapeutic Class English
Toxication reduction, anthelmintic, dampness removal, and itching control
Therapeutic Class Chinese
解毒杀虫燥湿止痒
Functions
induce subsidence of swelling and remove toxic substances, cause purgation
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAB3015-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx692 Ba Du Ointment 拔毒膏
TCMFx3001 Ba Du Ointment 拔毒膏
TCMFx2990 Bai Hua She Ointment 白花蛇膏
TCMFx3418 Die Da Wan Hua You 跌打万花油
TCMFx3743 Du Ji Du Jiao Ointment 杜记独角膏
TCMFx3330 Feng Shang Zhi Tong Ointment 风伤止痛膏
TCMFx4678 Nao Sha Ointment 硇砂膏
TCMFx5265 Quan Ji Ba Du Ointment 全鸡拔毒膏
TCMFx5798 Run Ji Pi Fu Ointment 润肌皮肤膏
TCMFx5694 Shang Ke Wan Hua You 伤科万花油
TCMF5332 Wan Ling Jin Gu Ointment 万灵筋骨膏
TCMFx6045 Xiao He Ointment 消核膏
TCMFx6821 Zhan Jiang Chan Chu Ointment 湛江蟾蜍膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT289 TBXAS1 Thromboxane-A synthase Isomerase P24557
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1255 Human immunodeficiency virus 1
TCMT1294 Human parainfluenza virus 3
TCMT1463 Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC5886
Formula: C27H22O18

Ingredient ID: TCMC4480
Formula: C20H32

Ingredient ID: TCMC4130
Formula: C18H34O3

Ingredient ID: TCMC3830
Formula: C18H36O4

Ingredient ID: TCMC3005
Formula: C8H14O4

Ingredient ID: TCMC2879
Formula: C10H18O4

Ingredient ID: TCMC2841
Formula: C7H12O4

Ingredient ID: TCMC2670
Formula: C15H26O2

Ingredient ID: TCMC2107
Formula: C29H48O

Ingredient ID: TCMC2017
Formula: C8H8N2O2

Ingredient ID: TCMC1972
Formula: C5H5N

Ingredient ID: TCMC1151
Formula: C15H12O8

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1151 C15H12O8 Ethylbrevifolin Carboxylate 320.05 -1.7587 2.23 -0.497 5 3 130.36 7 3 23 0
TCMC1972 C5H5N Pyridine 79.04 0 1.9 1.4 1 0 12.89 0 1 6 0
TCMC2017 C8H8N2O2 Ricinine 164.06 -0.7774 1.9 -0.09 4 0 53.33 3 1 12 0
TCMC2107 C29H48O Stigmasterol 412.37 1.2566 4.54 11.071 1 1 20.23 12 4 30 1
TCMC2670 C15H26O2 5-Epi-Eudesm-4(15)-Ene-1Beta,6Beta-Diol 238.19 -0.009 2.89 2.414 2 2 40.46 6 2 17 0
TCMC2841 C7H12O4 Dimelic Acid 158.0579088 -2.6296 1.79 -0.387 4 0 80.26 6 0 11 0
TCMC2879 C10H18O4 Sebacic Acid 200.104859 -3.4936 2.12 1.32 4 0 80.26 9 0 14 0
TCMC3005 C8H14O4 Suberic Acid 172.0735589 -2.9176 1.9 0.182 4 0 80.26 7 0 12 0
TCMC3830 C18H36O4 9,10-Dihydroxystearic Acid 315.2535346 -5.5969 3 4.901 4 2 80.59 16 0 22 1
TCMC4130 C18H34O3 Ricinoleic Acid 297.2429699 -3.2432 3.11 5.626 3 1 60.36 15 0 21 2
TCMC4480 C20H32 Cosbene 272.250401 4.4456 3.66 7.821 0 0 0 0 2 20 1
TCMC5886 C27H22O18 Corilagin 634.0806139 -5.5485 2.45 -1.779 9 11 310.66 3 5 45 1

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1. General Information of the Component  
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3. Putative Targets  
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