Component: Semen juglandis 核桃


Description of the Component

Component ID
TCMH820
Latin Name
Semen juglandis
English Name
English walnut seed
Chinese Pinyin Name
He Tao
中文名
核桃
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF989 Pei Kun Pills 培坤丸
TCMFx6251 Xiao Shi Tablets 消石片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT152 PRKCB Protein kinase C beta Kinase P05771
TCMT153 PRKCG Protein kinase C gamma Kinase P05129
TCMT154 PRKCD Protein kinase C delta Kinase Q05655
TCMT155 PRKCE Protein kinase C epsilon Kinase Q02156
TCMT191 STAT3 Signal transducer and activator of transcription 3 Transcription factor P40763
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1226 Klebsiella pneumoniae
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1438 Plasmodium falciparum
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans

Ingredient Structrues

Ingredient ID: TCMC2200
Formula: C9H11NO3

Ingredient ID: TCMC2062
Formula: C3H7NO3

Ingredient ID: TCMC1881
Formula: C36H56O8

Ingredient ID: TCMC1832
Formula: C16H30O2

Ingredient ID: TCMC164
Formula: C3H7NO2S

Ingredient ID: TCMC1513
Formula: C5H9NO2

Ingredient ID: TCMC1512
Formula: C9H11NO2

Ingredient ID: TCMC1459
Formula: C3H7NO2

Ingredient ID: TCMC1427
Formula: C10H6O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC164 C3H7NO2S (R)-Cysteine 121.02 -0.6242 1.35 -2.575 3 2 102.12 5 0 7 0
TCMC1427 C10H6O3 Juglone 174.03 -0.7335 2.23 0.575 2 1 54.37 1 2 13 0
TCMC1459 C3H7NO2 L-Alanine 89.05 -1.0955 1.46 -2.824 3 2 63.32 4 0 6 0
TCMC1512 C9H11NO2 L-Phenylalanine 165.08 -1.0844 2.12 0.441 3 2 63.32 5 1 12 0
TCMC1513 C5H9NO2 L-Proline 115.06 -1.3817 1.68 -0.185 3 2 49.33 2 1 8 0
TCMC1832 C16H30O2 Palmitoleic Acid 254.22 -1.7667 3 7.054 2 1 37.3 15 0 18 2
TCMC1881 C36H56O8 Phorbol Myristate Acetate 616.4 -3.4367 4.54 6.511 8 3 130.36 26 4 44 2
TCMC2062 C3H7NO3 Serine 105.04 -1.5955 1.35 -3.956 4 3 83.55 5 0 7 0
TCMC2200 C9H11NO3 Tyrosine 181.07 -1.5447 2.01 -1.577 3 3 83.55 6 1 13 0

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