Component: Dianthus superbus 瞿麦


Description of the Component

Component ID
 TCMH1706
Latin Name
 Dianthus superbus
English Name
 Lilac pink
Chinese Pinyin Name
 Qu Mai
中文名
 瞿麦
TCM Properties
 Cold,Bitter
TCM Meridians
 Bladder,Small Intestine,Heart
Therapeutic Class English
 For promoting diuresis and penetrating dampness
Therapeutic Class Chinese
 利水渗湿
Functions
 relieve dysuria, and stimulate menstrual discharge
Toxicity
 NA
Geo-authentic habitats (道地产区)
 NA
Reference
 Chinese Pharmacopoeia (2015)
Barcode ID
 ITSAJ4556-14
Barcode Source
 BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2434 Added Flavor DFZ Heat Clearing Decoction 加味地肤子汤
TCMF7309 Ba Zheng Powder 八正散
TCMF2993 Ba Zheng Recipe 八正合剂
TCMF229 Ba Zheng Recipe 八正合剂
TCMF1989 Combined Yi Bai Multi-Ingredient Recipe
TCMFx2103 Cortex Moutan Radicis Clearing Decoction 牡丹皮汤
TCMFx2249 Decoction for Clearing Away Lung Heat 清肺饮子
TCMF2101 Eight Health Restoring Powder 八珍散
TCMF2668 Eight-Herb Powder for Rectification 八正散
TCMF14 Fen Qing Wu Lin Pills 分清五淋丸
TCMF2544 Fenqing Wulin Pills 分清五淋丸
TCMF3427 Fu Shen Ning Tablets 复肾宁片
TCMF4148 Jin Sha Wu Lin Pills 金砂五淋丸
TCMF2116 Lithagogue Infusion 排石冲剂
TCMFx4435 Pai Shi Granules 排石颗粒
TCMFx4427 Pai Shi Ointment 排石膏
TCMFx1000 Pai Shi Granules 排石颗粒
TCMFx2489 Powder of Dianthi
TCMF2124 Powder of Eight Ingredients to Clear Heat and Dampness 八正散
TCMF2251 Powder of Pyrrosiae 石韦散
TCMF1088 Qing Lin Granules 清淋颗粒
TCMF5427 Qing Lin Infusion 清淋冲剂
TCMF5880 Qing Xue Nei Xiao Pills 清血内消丸
TCMFx3172 Shen Bie Jia Jian Pills 参鳖甲煎丸
TCMF5504 Shen Shi Tong Infusion 肾石通冲剂
TCMF5512 Shen Shu Infusion 肾舒冲剂
TCMFx5726 Shuang Xiang Pai Shi Granules 双香排石颗粒
TCMF1758 SQGCDZ Nephritis Decoction
TCMF972 Tong Ru Granules 通乳颗粒
TCMF5928 Tong Ru Granules 通乳颗粒
TCMFx1752 Trichosanthis and Dianthi Pills 瓜蒌瞿麦丸
TCMF1996 Turbid Control Decoction 苓薏败酱汤

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT337 XPO1 Exportin-1 Unclassified O14980
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT506 PTK2B Protein tyrosine kinase 2 beta Kinase Q14289
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1243 Aspergillus flavus
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC949
Formula: C9H6O2

Ingredient ID: TCMC779
Formula: C14H12O3

Ingredient ID: TCMC775
Formula: C14H12O2

Ingredient ID: TCMC706
Formula: C14H8O2

Ingredient ID: TCMC495
Formula: C7H6O2

Ingredient ID: TCMC405
Formula: C20H19N3O2

Ingredient ID: TCMC1839
Formula: C7H6O3

Ingredient ID: TCMC1159
Formula: C10H12O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC405 C20H19N3O2 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15 0.4793 3.11 4.231 4 1 58.22 6 4 25 0
TCMC495 C7H6O2 4-Hydroxybenzaldehyde 122.04 -0.6527 2.01 1.484 1 1 37.3 2 1 9 0
TCMC706 C14H8O2 Anthraquinone 208.05 -0.5276 2.78 4.074 2 0 34.14 0 3 16 0
TCMC775 C14H12O2 Benzyl Benzoate 212.08 -0.0795 2.78 5.895 2 0 26.3 4 2 16 1
TCMC779 C14H12O3 Benzyl Salicylate 228.08 -0.5398 2.67 5.493 2 1 46.53 5 2 17 1
TCMC949 C9H6O2 Coumarin 146.04 0.27 2.23 2.706 1 0 26.3 0 2 11 0
TCMC1159 C10H12O2 Eugenol 164.08 0.5166 2.34 2.484 0 1 29.46 5 1 12 0
TCMC1839 C7H6O3 Paraben 138.03 -0.7001 1.9 1.07 2 2 57.53 3 1 10 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)