TCM Prescription: Cortex Moutan Radicis Clearing Decoction



Prescription Description
Prescription IDTCMFx2103
Pinyin NameMu Dan Pi Tang
Chinese Name牡丹皮汤
English NameCortex Moutan Radicis Clearing Decoction
Function Description
IndicationsNone
Disease ICD-11 Category
Human Tissues Associated with Indication
ReferenceChinese Classical Prescriptions
Reference Book/linkISBN 7-5023-3930-2
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH1513 Paeonia moutan 牡丹皮 TCMH1513
TCMH1531 Akebia quinata 木通 TCMH1531 ITSAJ4440-14
TCMH170 Dioscorea hypoglauca 萆薢 TCMH170 GBVU109-13, GBVT4961-13
TCMH923 Radix trichosanthis 花粉 TCMH923
TCMH1706 Dianthus superbus 瞿麦 TCMH1706 ITSAJ4556-14
TCMH2581 Alisma orientale 泽泻 TCMH2581 KC573871
TCMH2288 Herba plantaginis minutae 小车前 TCMH2288
TCMH628 Glycyrrhiza uralensis 甘草 TCMH628 ITSAM892-14
TCMH2486 Coix lacryma- jobi var. ma - yuen 薏苡仁 TCMH2486
Reference: Chinese Classical Prescriptions

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT127 PARP1 Poly [ADP-ribose] polymerase-1 Transferase P09874
TCMT128 TNKS2 Tankyrase-2 Transferase Q9H2K2
TCMT129 TNKS Tankyrase-1 Transferase O95271
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT209 HSD11B2 11-beta-hydroxysteroid dehydrogenase 2 Oxidoreductase P80365
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT231 GBA2 Beta-glucosidase Hydrolase Q9HCG7
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT318 HKDC1 Putative hexokinase HKDC1 Transferase Q2TB90
TCMT344 AOX1 Aldehyde oxidase Oxidoreductase Q06278
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT47 BCL2 Apoptosis regulator Bcl-2 Ion channel P10415
TCMT506 PTK2B Protein tyrosine kinase 2 beta Kinase Q14289
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT591 ESRRA Estrogen-related receptor alpha Nuclear receptor P11474
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT752 CSNK2A1 Casein kinase II alpha Kinase P68400
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT910 ESRRB Estrogen-related receptor beta Nuclear receptor O95718


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1170 Enterobacter cloacae
TCMT1172 Staphylococcus aureus subsp. aureus RN4220
TCMT1174 Mycobacterium bovis BCG
TCMT1175 Human immunodeficiency virus
TCMT1176 Streptococcus pneumoniae
TCMT1177 Haemophilus influenzae
TCMT1178 Actinomyces viscosus
TCMT1179 Escherichia coli ATCC 8739
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1182 Streptococcus sanguinis
TCMT1184 Mycobacterium fortuitum
TCMT1185 Mycobacterium phlei
TCMT1186 Plasmodium yoelii yoelii
TCMT1187 Enterococcus faecalis ATCC 29212
TCMT1189 Pseudomonas fluorescens
TCMT1191 Bacillus megaterium
TCMT1192 Bacteria
TCMT1193 Staphylococcus
TCMT1194 Shigella sonnei
TCMT1196 Salmonella
TCMT1198 Serratia marcescens
TCMT1199 Streptococcus sp. 'group A'
TCMT1200 Bacillus thuringiensis
TCMT1201 Staphylococcus epidermidis ATCC 12228
TCMT1202 Mycoplasma hominis
TCMT1203 Mycoplasma pneumoniae
TCMT1204 Clostridium perfringens
TCMT1207 Legionella pneumophila
TCMT1208 Escherichia coli K12
TCMT1209 Staphylococcus haemolyticus
TCMT1211 Fusobacterium nucleatum
TCMT1212 Verticillium dahliae
TCMT1213 Neisseria gonorrhoeae
TCMT1214 Enterococcus faecium
TCMT1215 Pseudomonas aeruginosa PAO1
TCMT1216 Vibrio cholerae
TCMT1217 Bacillus anthracis
TCMT1218 Staphylococcus aureus
TCMT1219 Enterococcus
TCMT1220 Streptococcus pneumoniae R6
TCMT1223 Staphylococcus epidermidis
TCMT1224 Proteus mirabilis
TCMT1226 Klebsiella pneumoniae
TCMT1227 Streptococcus
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1234 Bacillus coagulans
TCMT1235 Clostridium sporogenes
TCMT1236 Mycobacterium bovis
TCMT1237 Mycobacterium kansasii
TCMT1238 Mycobacterium xenopi
TCMT1239 Mycobacterium marinum
TCMT1243 Aspergillus flavus
TCMT1244 Staphylococcus saprophyticus
TCMT1245 Phytophthora cactorum
TCMT1246 Escherichia coli
TCMT1248 Hepatitis C virus
TCMT1249 Dengue virus 2
TCMT1251 Candida albicans
TCMT1252 Alcaligenes faecalis
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1260 Streptococcus agalactiae
TCMT1262 Mycoplasma putrefaciens
TCMT1266 Mycobacterium abscessus
TCMT1267 Mycobacterium chelonae
TCMT1271 Shigella flexneri
TCMT1272 Campylobacter jejuni
TCMT1273 Pseudomonas putida
TCMT1274 Shigella boydii
TCMT1276 Klebsiella
TCMT1277 Serratia
TCMT1278 Pseudomonas
TCMT1281 Clostridium difficile
TCMT1284 Penicillium expansum
TCMT1286 Bacillus cereus
TCMT1287 Bacillus subtilis subsp. spizizenii ATCC 6633
TCMT1289 Shigella dysenteriae
TCMT1290 Acinetobacter calcoaceticus
TCMT1291 Haemophilus parainfluenzae
TCMT1294 Human parainfluenza virus 3
TCMT1299 Morganella morganii
TCMT1300 Enterobacter
TCMT1301 Klebsiella sp.
TCMT1303 Bacillus
TCMT1304 Staphylococcus capitis
TCMT1305 Salmonella enteritidis
TCMT1307 Penicillium marneffei
TCMT1309 Aspergillus clavatus
TCMT1310 Enterococcus hirae
TCMT1314 Streptococcus viridans
TCMT1315 Streptococcus sp.
TCMT1317 Staphylococcus lentus
TCMT1321 Staphylococcus hominis
TCMT1322 Streptococcus mitis
TCMT1326 Shigella
TCMT1331 Acinetobacter sp.
TCMT1332 Bacillus licheniformis
TCMT1334 Chlamydia trachomatis
TCMT1340 Staphylococcus faecalis
TCMT1341 Streptococcus oralis
TCMT1342 Streptococcus salivarius
TCMT1345 Prevotella loescheii
TCMT1346 Helicobacter pylori
TCMT1349 Helicobacter pylori SS1
TCMT1355 Rhodococcus equi
TCMT1356 Campylobacter coli
TCMT1358 Bacteroides vulgatus
TCMT1361 Neisseria meningitidis
TCMT1362 Bordetella pertussis
TCMT1363 Peptostreptococcus anaerobius
TCMT1366 Prevotella bivia
TCMT1371 Veillonella parvula
TCMT1375 Clostridium tetani
TCMT1377 Staphylococcus lugdunensis
TCMT1378 Acinetobacter haemolyticus
TCMT1381 Listeria innocua
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1383 Streptomyces griseus
TCMT1388 Prevotella disiens
TCMT1389 Klebsiella oxytoca
TCMT1393 Vibrio sp.
TCMT1394 Mycobacterium aurum
TCMT1395 Staphylococcus sp.
TCMT1396 Fusobacterium
TCMT1399 Chlamydophila pneumoniae
TCMT1400 Mycobacterium mageritense
TCMT1401 Staphylococcus warneri
TCMT1402 Staphylococcus cohnii
TCMT1403 Streptococcus constellatus
TCMT1404 Streptococcus intermedius
TCMT1406 Mycobacterium leprae
TCMT1407 Aeromonas punctata
TCMT1408 Colletotrichum gloeosporioides
TCMT1409 Escherichia coli O157:H7
TCMT1410 Listeria monocytogenes
TCMT1411 Vibrio parahaemolyticus
TCMT1412 Salmonella typhimurium
TCMT1413 Vibrio splendidus
TCMT1414 Vibrio vulnificus
TCMT1415 Vibrio fluvialis
TCMT1416 Plesiomonas shigelloides
TCMT1417 Aeromonas sobria
TCMT1418 Enterobacteriaceae
TCMT1420 Klebsiella pneumoniae subsp. ozaenae
TCMT1421 Vibrio mimicus
TCMT1422 Clostridium histolyticum
TCMT1423 Peptostreptococcus
TCMT1424 Haemophilus ducreyi
TCMT1425 Moraxella bovis
TCMT1427 Proteus inconstans
TCMT1429 Acinetobacter pittii
TCMT1431 Coxiella burnetii
TCMT1432 Serratia sp.
TCMT1434 Plesiomonas
TCMT1435 Corynebacterium
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1443 Leishmania amazonensis
TCMT1444 Fusarium oxysporum
TCMT1447 Respiratory syncytial virus
TCMT1448 Enterobacter aerogenes
TCMT1449 Influenza A virus
TCMT1450 Plasmodium falciparum 3D7
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1457 Leishmania major
TCMT1458 Filobasidiella neoformans
TCMT1460 Mycobacterium intracellulare
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway