Component ID |
TCMH278 |
Latin Name |
Juncus effusus |
English Name |
Common rush |
Chinese Pinyin Name |
Chuan Deng Xin Cao |
中文名 |
川灯心草 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
SATCM |
Barcode ID |
ITSAD4376-14 |
Barcode Source |
BOLDSYSTEMS |
Prescription ID | Prescription English Name | Prescription Chinese Name |
---|---|---|
TCMFx3192 | Deng Xin Zhi Xue Syrup | 灯心止血糠浆 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
TCMT164 | PTGS1 | Cyclooxygenase-1 | Oxidoreductase | P23219 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT213 | SLC22A1 | Solute carrier family 22 member 1 | Transporter | O15245 |
TCMT214 | MGLL | Monoglyceride lipase | Unclassified | Q99685 |
TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
TCMT307 | KCNH2 | HERG | Ion channel | Q12809 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT334 | EBP | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | Isomerase | Q15125 |
TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
TCMT434 | JAK2 | Tyrosine-protein kinase JAK2 | Kinase | O60674 |
TCMT559 | ADRB2 | Beta-2 adrenergic receptor | GPCR | P07550 |
TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
TCMT81 | ALOX12 | Arachidonate 12-lipoxygenase | Oxidoreductase | P18054 |
TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
TCMT881 | BBOX1 | Gamma-butyrobetaine dioxygenase | Oxidoreductase | O75936 |
Target ID | Target Name |
---|---|
TCMT1218 | Staphylococcus aureus |
TCMT1251 | Candida albicans |
TCMT1438 | Plasmodium falciparum |
TCMT1439 | Mycobacterium smegmatis |
TCMT1455 | Mycobacterium tuberculosis H37Rv |
TCMT1458 | Filobasidiella neoformans |
Ingredient ID: TCMC877
Formula: C15H22O10
Ingredient ID: TCMC747
Formula: C15H22O9
Ingredient ID: TCMC542
Formula: C20H20O8
Ingredient ID: TCMC495
Formula: C7H6O2
Ingredient ID: TCMC2753
Formula: C18H18O2
Ingredient ID: TCMC2250
Formula: C26H28ClNO
Ingredient ID: TCMC2163
Formula: C6H12N2S4
Ingredient ID: TCMC1535
Formula: C6H14O6
Ingredient ID: TCMC1098
Formula: C17H16O2
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC495 | C7H6O2 | 4-Hydroxybenzaldehyde | 122.04 | -0.6527 | 2.01 | 1.484 | 1 | 1 | 37.3 | 2 | 1 | 9 | 0 |
TCMC542 | C20H20O8 | 5-Demethylnobiletin | 388.12 | -1.2229 | 2.78 | 1.273 | 1 | 1 | 92.68 | 12 | 3 | 28 | 0 |
TCMC747 | C15H22O9 | Aucubin | 346.13 | -3.5817 | 2.12 | -2.39 | 9 | 6 | 149.07 | 10 | 3 | 24 | 1 |
TCMC877 | C15H22O10 | Catalpol | 362.12 | -4.3433 | 2.01 | -2.707 | 10 | 6 | 161.6 | 10 | 4 | 25 | 1 |
TCMC1098 | C17H16O2 | Effusol | 252.12 | 0.5537 | 3.11 | 4.566 | 0 | 2 | 40.46 | 4 | 3 | 19 | 0 |
TCMC1535 | C6H14O6 | Mannitol | 182.08 | -2.9402 | 1.46 | -3.896 | 6 | 6 | 121.38 | 11 | 0 | 12 | 1 |
TCMC2163 | C6H12N2S4 | Thiram | 239.99 | 3.1558 | 1.46 | 1.548 | 2 | 0 | 121.26 | 9 | 0 | 12 | 0 |
TCMC2250 | C26H28ClNO | Zuclomiphene | 405.19 | 1.2286 | 3.99 | 9.846 | 1 | 0 | 12.47 | 12 | 3 | 29 | 1 |
TCMC2753 | C18H18O2 | 5-Ethenyl-1,6-Dimethyl-9,10-Dihydrophenanthrene-2,7-Diol | 266.13 | 1.1957 | 3.22 | 4.678 | 0 | 2 | 40.46 | 5 | 3 | 20 | 0 |