Component: Juncus effusus 川灯心草


Description of the Component

Component ID
TCMH278
Latin Name
Juncus effusus
English Name
Common rush
Chinese Pinyin Name
Chuan Deng Xin Cao
中文名
川灯心草
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
SATCM
Barcode ID
ITSAD4376-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3192 Deng Xin Zhi Xue Syrup 灯心止血糠浆

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT213 SLC22A1 Solute carrier family 22 member 1 Transporter O15245
TCMT214 MGLL Monoglyceride lipase Unclassified Q99685
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT334 EBP 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase Isomerase Q15125
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT434 JAK2 Tyrosine-protein kinase JAK2 Kinase O60674
TCMT559 ADRB2 Beta-2 adrenergic receptor GPCR P07550
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT881 BBOX1 Gamma-butyrobetaine dioxygenase Oxidoreductase O75936


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1251 Candida albicans
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans

Ingredient Structrues

Ingredient ID: TCMC877
Formula: C15H22O10

Ingredient ID: TCMC747
Formula: C15H22O9

Ingredient ID: TCMC542
Formula: C20H20O8

Ingredient ID: TCMC495
Formula: C7H6O2

Ingredient ID: TCMC2753
Formula: C18H18O2

Ingredient ID: TCMC2250
Formula: C26H28ClNO

Ingredient ID: TCMC2163
Formula: C6H12N2S4

Ingredient ID: TCMC1535
Formula: C6H14O6

Ingredient ID: TCMC1098
Formula: C17H16O2

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC495 C7H6O2 4-Hydroxybenzaldehyde 122.04 -0.6527 2.01 1.484 1 1 37.3 2 1 9 0
TCMC542 C20H20O8 5-Demethylnobiletin 388.12 -1.2229 2.78 1.273 1 1 92.68 12 3 28 0
TCMC747 C15H22O9 Aucubin 346.13 -3.5817 2.12 -2.39 9 6 149.07 10 3 24 1
TCMC877 C15H22O10 Catalpol 362.12 -4.3433 2.01 -2.707 10 6 161.6 10 4 25 1
TCMC1098 C17H16O2 Effusol 252.12 0.5537 3.11 4.566 0 2 40.46 4 3 19 0
TCMC1535 C6H14O6 Mannitol 182.08 -2.9402 1.46 -3.896 6 6 121.38 11 0 12 1
TCMC2163 C6H12N2S4 Thiram 239.99 3.1558 1.46 1.548 2 0 121.26 9 0 12 0
TCMC2250 C26H28ClNO Zuclomiphene 405.19 1.2286 3.99 9.846 1 0 12.47 12 3 29 1
TCMC2753 C18H18O2 5-Ethenyl-1,6-Dimethyl-9,10-Dihydrophenanthrene-2,7-Diol 266.13 1.1957 3.22 4.678 0 2 40.46 5 3 20 0

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1. General Information of the Component  
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3. Putative Targets  
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