Prescription Description
| Prescription ID | TCMFx3192 |
| Pinyin Name | Deng Xin Zhi Xue Tang Jiang |
| Chinese Name | 灯心止血糠浆 |
| English Name | Deng Xin Zhi Xue Syrup |
| Function Description | 便血, 鼻衄, 恶露不绝 |
| Indications | Postpartum lochiorrhea disorder, Epistaxis, Melena |
| Disease ICD-11 Category |
SC13 [Postpartum lochiorrhea disorder (TM1), 恶露不绝 (TM1)
]; MD20 [Epistaxis, 鼻衄 ]; ME24.A4 [Melaena, 黑便 ]; |
| Human Tissues Associated with Indication | Large Intestine, Nose |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH278 | Juncus effusus | 川灯心草 | TCMH278 | ITSAD4376-14 |
| TCMH1736 | NA | 绒毛龙穿草 | TCMH1736 | |
| TCMH2113 | Herba acalyphae | 铁苋菜 | TCMH2113 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT190 | PTPN2 | T-cell protein-tyrosine phosphatase | Hydrolase | P17706 |
| TCMT214 | MGLL | Monoglyceride lipase | Unclassified | Q99685 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
| TCMT307 | KCNH2 | HERG | Ion channel | Q12809 |
| TCMT334 | EBP | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | Isomerase | Q15125 |
| TCMT434 | JAK2 | Tyrosine-protein kinase JAK2 | Kinase | O60674 |
| TCMT563 | CDC25B | Dual specificity phosphatase Cdc25B | Hydrolase | P30305 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT881 | BBOX1 | Gamma-butyrobetaine dioxygenase | Oxidoreductase | O75936 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1178 | Actinomyces viscosus |
| TCMT1212 | Verticillium dahliae |
| TCMT1214 | Enterococcus faecium |
| TCMT1218 | Staphylococcus aureus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1246 | Escherichia coli |
| TCMT1248 | Hepatitis C virus |
| TCMT1251 | Candida albicans |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1283 | Human enterovirus 71 |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples