Prescription Description
| Prescription ID | TCMF1989 |
| Pinyin Name | Fu Fang Yi Bai He Ji |
| Chinese Name | |
| English Name | Combined Yi Bai Multi-Ingredient Recipe |
| Function Description | |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | |
| Reference | Chinese Classical Prescriptions |
| Reference Book/link | ISBN 7-5023-3930-2 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH2473 | Leonurus japonicus | 益母草 | TCMH2473 | ITSAN1807-14 |
| TCMH949 | Phellodendron amurense | 黄柏 | TCMH949 | ITSAM1586-14 |
| TCMH1531 | Akebia quinata | 木通 | TCMH1531 | ITSAJ4440-14 |
| TCMH241 | Plantago asiatica | 车前子 | TCMH241 | ITSAB3641-14 |
| TCMH177 | Polygonum aviculare | 萹蓄 | TCMH177 | ITSAG3700-14 |
| TCMH1706 | Dianthus superbus | 瞿麦 | TCMH1706 | ITSAJ4556-14 |
| TCMH2641 | Gardenia jasminoides | 栀子 | TCMH2641 | ITSAJ4473-14 |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
Showing 1 to 10 of 97 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1198 | Serratia marcescens |
Showing 1 to 10 of 72 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, APEX1, AXL, BCL2, CYP1B1, MMP9, SRC | 3.39876 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, DNMT1, FABP3, HSD17B2, KDR, MMP2, SRC | 2.06009 |
| [BP] GO:0001666 | response to hypoxia | BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, SRC, TERT | 3.30584 |
| [BP] GO:0001932 | regulation of protein phosphorylation | APP, BCL2, CDC25B, DRD1, DRD2, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PRKCA, PTPN1, SRC, XDH | 2.25112 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | APP, BCL2, CDC25B, DRD2, FLT3, KDR, KIT, MMP9, PRKCA, PTPN1, SRC, XDH | 2.13316 |
| [BP] GO:0002244 | None | BCL2, FLT3, KIT, TOP2A | 2.00946 |
| [BP] GO:0002318 | myeloid progenitor cell differentiation | FLT3, KIT | 2.10069 |
| [BP] GO:0002320 | lymphoid progenitor cell differentiation | BCL2, FLT3, KIT | 3.053 |
| [BP] GO:0002521 | leukocyte differentiation | AXL, BCL2, FLT3, FUT7, GLO1, KIT, MMP9, RORC | 3.28575 |
| [BP] GO:0003006 | developmental process involved in reproduction | ALPL, AXL, BCL2, CDC25B, CYP19A1, ESR1, ESRRB, HSD17B2, KIT, SRC | 2.41249 |
Showing 1 to 10 of 353 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6421 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, KIT, PIM1 | 2.1679 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MET, IGF1R | 4.0241 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5478 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2, PRKCA | 0.7742 |
| African trypanosomiasis_Homo sapiens_hsa05143 | PRKCA | 0.7126 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1, PRKCA, F3 | 3.585 |
| Alcoholism_Homo sapiens_hsa05034 | DRD1, DRD2 | 0.6801 |
| Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | PRKCA | 0.5093 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2, PRKCA | 1.5805 |
Showing 1 to 10 of 162 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples