| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CDK6, CHRM1, CHRM3, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS1, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
20.828 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
ADRB2, AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, GRIK5, GRM5, HSD11B2, HSD17B2, IGF1R, INSR, MMP2, MMP9, PIK3CA, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
16.0982 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRB2, AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, PIK3CA, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
16.0036 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F10, F3, FLT3, GPR35, GRM1, HCAR2, HSPA1A, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.7337 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F10, F3, FLT3, GPR35, GRM1, HCAR2, HSPA1A, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.7187 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ADRB2, AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, PIK3CA, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
14.4009 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, ERBB2, ESR1, FABP3, FABP4, FUT7, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, SOAT1, SOAT2, TRPV1 |
13.1341 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
12.7453 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRB2, AKR1B1, ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, ESRRA, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, KIT, MMP2, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1 |
12.6276 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CACNA1C, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.564 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, F10, F3, FLT3, GPR35, GRM1, HSPA1A, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.4293 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CACNA1C, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.3598 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
12.3549 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FLT3, HSD11B2, PRKCE, PRKCG, PTAFR, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
11.982 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB2, APEX1, APP, AXL, BCL2, CA2, CA7, CACNA1C, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F10, F3, GPR35, GRIK5, GRM5, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
11.5203 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADRB2, APP, BACE1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, KIT, PRKCE, PTGS2 |
11.5203 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADRB2, APP, BACE1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, KIT, PRKCE, PTGS2 |
11.5203 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CHRM1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ERBB2, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
11.5203 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, PRKCA, PTAFR, PTGES, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
11.5203 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
ADRB2, AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GRIK5, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TERT, TRPV1 |
11.4045 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRB1, ADRB2, APP, BCL2, CDC25B, CHRM5, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.3806 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AXL, BCL2, CYP1B1, DRD2, EGFR, ERBB2, F10, F3, FLT3, GPR35, GRM1, HSPA1A, INSR, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
11.3274 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ADRB2, APP, BCL2, CDC25B, CHRM5, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.2868 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRB1, ADRB2, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, SOAT1, SOAT2, SRC, TERT, TRPV1 |
11.1376 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
ADRB2, AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GRIK5, GRM5, IGF1R, INSR, KDR, KIT, MMP2, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
11.0621 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
11.0325 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, ERBB2, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
10.8229 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HSPA1A, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.8229 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F10, F3, FLT3, GPR35, GRM1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
10.797 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CACNA1C, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, ERBB2, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
10.7927 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ADRB2, APP, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ERBB2, ESRRB, FABP3, FLT3, GRM1, GRM5, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.7927 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRB1, ADRB2, APP, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ERBB2, ESRRB, FABP3, FLT3, GRM1, GRM5, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.7927 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.7151 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GRM1, GRM3, GRM5, GRM8 |
10.5369 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.46 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.2035 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
ADRB2, AKR1B1, APEX1, APP, AXL, CDK6, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SRC, TRPV1 |
10.1671 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
10.1047 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, APP, AXL, BCL2, CACNA1C, CHRM1, CHRM3, CHRM5, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GRM1, GRM5, GRM8, HSD11B2, HSD17B2, IGF1R, INSR, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TNKS2, TRPV1, TYR |
10.0498 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
9.95948 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, ESR1, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, SOAT1, SOAT2 |
9.95881 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HSPA1A, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
9.89204 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APP, AXL, BCL2, CA1, CA2, CACNA1C, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
9.81362 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.7807 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CHRM2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GRIK5, GRM1, GRM5, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
9.77082 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GRM1, GRM3, GRM5, GRM8 |
9.67233 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HSPA1A, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
9.65222 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.6349 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, GPR35, GRIK5, GRM1, GRM5, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, SOAT1, SOAT2, TRPV1 |
9.56782 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.51547 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
9.42169 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ADRB2, APP, AXL, BCL2, CA2, CA7, CACNA1C, CHRM1, CYP19A1, DRD1, DRD2, DRD3, EGFR, ERBB2, GPR35, GRIK5, GRM5, HCAR2, HSPA1A, INSR, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
9.36681 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM1, CHRM2, CHRM3, CHRM5, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8 |
9.31812 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
9.28159 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CACNA1C, CDK6, DRD1, DRD2, DRD3, EGFR, HCAR2, KDR, MIF, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
9.21407 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, ADRB2, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, ERBB2, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
9.21407 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, FUT7, GBA2, GLO1, HSPA1A, MIF, PIK3CA, PIM1, PPARA, PTAFR, PTGES, PTGS1, PTGS2, SOAT1, SOAT2, TYR, XDH |
9.12234 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, KIT, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TEK, TRPV1 |
9.07103 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP2, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
9.01973 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, GRM1, HSD11B2, HSPA1A, KIT, MMP2, PPARA, PRKCB, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
8.99637 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GRM1, GRM3, GRM5, HSPA1A, IGF1R, INSR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.98356 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
8.95405 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GRM1, GRM3, GRM5, HSPA1A, IGF1R, INSR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
8.95405 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
8.89532 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, ERBB2, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
8.89532 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
ADRB2, AKR1B1, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FABP4, FLT3, GRIK5, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP2, MMP9, NUAK1, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
8.81746 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRB2, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.80012 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HSPA1A, IGF1R, KDR, MIF, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
8.7874 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, ESR1, F3, FLT3, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, PIM1, PRKCA, PTAFR, PTGS2, TEK, TERT |
8.78103 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRB1, ADRB2, APP, AXL, BCL2, CA2, CACNA1C, CDK6, CHRM1, CHRM2, CHRM3, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F3, GPR35, GRM1, HCAR2, HSPA1A, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
8.71935 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, ERBB2, FABP3, FABP4, FUT7, GBA2, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, SOAT1, SOAT2 |
8.69716 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
8.65714 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, KIT, MMP9, PRKCD, PTGES, PTGS2, SRC, TERT |
8.59352 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRB1, ADRB2, CACNA1C, CHRM1, CHRM2, CHRM3, DRD2, DRD3, EGFR, GPR35, GRM1, HCAR2, KIT, PRKCA, PTAFR, PTGS2, SLC1A1, SMAD3, TRPV1 |
8.58536 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
8.45153 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ERBB2, ESR1, ESR2, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.34082 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HSPA1A, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.30279 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, PIM1, PRKCG, SRC, TEK |
8.27021 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2 |
8.27021 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.23161 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
8.20959 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, HSD11B2, KDR, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TRPV1 |
8.19722 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
8.15703 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, KIT, MET, MIF, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.13325 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
ADRB2, AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, ERBB2, ESR1, FLT3, GRM5, IGF1R, INSR, KIT, MMP2, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
8.05224 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, ADRB2, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, DRD1, DRD2, DRD3, EGFR, ERBB2, HCAR2, INSR, MIF, MMP12, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TERT, TRPV1 |
8.02238 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
8.01516 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRB2, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SOAT1, SRC, TEK, XDH |
8.00117 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2 |
7.97965 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD17B2, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PTGS2, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
7.97505 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, ADRB1, ADRB2, AKR1B1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.88305 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRB2, APP, BCL2, CDC25B, DRD2, EGFR, ERBB2, ESRRB, FLT3, GRM1, GRM5, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.78932 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
7.70889 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
7.68675 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, PRKCE, PTAFR, PTGES, PTGS2, RORC, SRC, TYR |
7.63918 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
7.62699 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRB1, ADRB2, APP, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ERBB2, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
7.56306 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRB1, ADRB2, AXL, BCL2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, PTGS2, SLC1A1, TEK, TRPV1 |
7.54973 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
7.52227 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRB1, ADRB2, DRD2, DRD3, DRD5, HSD11B2, PPARA, PTAFR, PTGS1, PTGS2, SMAD3 |
7.52227 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRB2, APP, BCL2, CDC25B, DRD2, EGFR, ERBB2, FLT3, GRM1, GRM5, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.51549 |
|
[BP] GO:0045776 |
None
|
ADORA1, ADRB1, ADRB2, DRD2, DRD3, DRD5, PPARA, PTAFR |
7.4826 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
7.46181 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
7.45545 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRB1, ADRB2, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, GRM5, IGF1R, INSR, KDR, KIT, MET, MIF, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, SRC, TEK |
7.45004 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
7.44422 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRB2, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.427 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRB1, ADRB2, APP, AXL, BCL2, CA2, CHRM3, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, HCAR2, HSPA1A, KDR, KIT, MET, MIF, MMP12, MMP9, PIM1, PRKCA, PRKCB, PRKCE, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
7.40816 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HCAR2, HSPA1A, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.39232 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM3, DRD1, DRD5, EGFR, PTAFR, PTGS2, SRC, TEK |
7.36108 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.34564 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, F10, F3, FLT3, GPR35, GRM1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.16685 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GRM5, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
7.13071 |
|
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
7.13071 |
|
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
7.13071 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRB2, APP, DRD2, EGFR, ERBB2, FLT3, GRM1, INSR, KDR, KIT, MIF, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
7.12716 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRB2, APP, BCL2, CDC25B, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, FABP4, FLT3, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
7.06454 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRB2, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ERBB2, ESRRB, FABP4, FLT3, GRM1, GRM5, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.01544 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, MIF, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
7.01544 |
|
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
7.00605 |
|
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
7.00605 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRB2, APP, DRD2, DUSP3, EGFR, ERBB2, FLT3, GRM1, IGF1R, INSR, KDR, KIT, MIF, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
6.97895 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRIK5, INSR, PTGS2, SLC1A1, SLC22A2, SLC22A3, SMAD3, TRPV1 |
6.93857 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, BCL2, CHRM1, CHRM3, CHRM5, CYP1A1, EGFR, ERBB2, ESR1, FLT3, KIT, MET, MIF, PIK3CB, PIM1, PRKCD, SRC, TEK, TYR |
6.93857 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.85456 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, DYRK1A, EGFR, ERBB2, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP2A |
6.80878 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.80034 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.77601 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRB2, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
6.75544 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRB2, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
6.72718 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CDK6, CYP19A1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, HSPA1A, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
6.72139 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, ADRB2, APP, BCL2, CA2, CA7, CACNA1C, CHRM1, DRD1, DRD2, DRD3, GPR35, GRM5, MIF, MMP9, PRKCD, PRKCE, PTAFR, PTGS2 |
6.71987 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.70997 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRB2, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ERBB2, FLT3, GRM1, GRM5, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.69885 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRB2, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GRM1, GRM5, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.69856 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
ADRB2, AKR1B1, APEX1, APP, DNMT1, DRD1, DRD5, EGFR, GRM5, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
6.67139 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRB1, ADRB2, AKR1B1, APP, BCL2, CHRM1, CHRM3, CHRM5, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM1, GRM5, GRM8, HSD11B2, INSR, KIT, PIK3CA, PRKCG, PTAFR, PTGS2, SOAT2, SRC, TEK, TRPV1, TYR |
6.65215 |
|
[BP] GO:0006811 |
None
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM5, DRD1, DRD2, DRD3, FABP3, GRIA2, GRIA4, GRIK5, PPARA, PRKCB, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
6.63565 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5, PTAFR |
6.54827 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.53474 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1, TEK |
6.53173 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRB1, ADRB2, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1, TEK |
6.49207 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TRPV1 |
6.43395 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, ADRB2, APP, AURKB, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, ESR1, FABP4, GPR35, GRM3, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
6.40148 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, DYRK1A, EGFR, ESR1, KIT, PPARA, PRKCG, RORC, SRC, TOP2A |
6.40148 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CACNA1C, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PRKCA, PRKCE, SLC22A1 |
6.40148 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.36393 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.36393 |
|
[BP] GO:0007200 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD5, ESR1, GRM5 |
6.32913 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2 |
6.32768 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.29733 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.28723 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADRB2, APP, CA2, CA7, DRD1, DRD2, EGFR, PRKCE, PTGS2 |
6.25809 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.25809 |
|
[BP] GO:1901652 |
response to peptide
|
ADRB2, AKR1B1, APEX1, APP, FABP3, GRM5, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
6.2029 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, APP, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD5, EGFR, ERBB2, HSD11B2, HSPA1A, KIT, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
6.19833 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FLT3, PTAFR, PTGS2, RORC, SRC, TRPV1 |
6.17386 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM3, DRD1, DRD5, EGFR, PTAFR, PTGS2 |
6.17348 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM3, DRD1, DRD5, EGFR, PTAFR, PTGS2 |
6.17348 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM3, DRD1, DRD5, EGFR, PTAFR, PTGS2, SRC, TEK |
6.12778 |
|
[BP] GO:0015872 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
6.1198 |
|
[BP] GO:0006940 |
None
|
ADORA1, ADRB2, CHRM1, CHRM2, CHRM3, KIT, PTAFR, PTGS2 |
6.09873 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
6.09873 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
6.08402 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, KDR, PRKCE, SRC, TRPV1 |
6.06958 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CHRM5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.04577 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRB2, BCL2, CDK6, CYP19A1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
6.04322 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.02757 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
ADRB1, ADRB2, APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
6.00941 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CHRM5, CYP1A1, DRD3, FABP3, FLT3, HCAR2, KIT, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
6.00941 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, ADRB2, CDC25B, DRD2, EGFR, ERBB2, FLT3, GRM1, GRM5, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.97538 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, ADRB2, AURKB, CDC25B, DRD2, EGFR, ERBB2, FLT3, GRM1, GRM5, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
5.95787 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM3, DRD1, DRD5, EGFR, PTAFR, PTGS2 |
5.94354 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, BCL2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HCAR2, HSPA1A, IGF1R, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
5.9228 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM3, DRD1, DRD5, EGFR, PTAFR, PTGS2 |
5.91588 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, MIF, PRKCA, PRKCE, SRC, TERT |
5.8949 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRB1, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CHRM5, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.88647 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
5.86618 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.85152 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.83534 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, ADRB2, APP, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, KDR, MET, MMP12, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
5.82685 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, ADRB2, APP, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GRM1, GRM5, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.80845 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
5.80665 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CHRM5, CSNK2A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.79654 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.77895 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CHRM1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, INSR, KIT, PRKCG, PTGS2 |
5.7719 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, ADRB2, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GRM1, GRM5, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
5.74459 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD2, DRD3, EGFR, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
5.72 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, KIT, PIK3CA, PPARA, SMAD3, SRC, TEK, TYR |
5.71416 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.70728 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
5.68644 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, ADRB2, APP, CDC25B, DRD2, DUSP3, EGFR, ERBB2, FABP4, FLT3, GRM1, GRM5, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
5.68255 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
5.65568 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, ADRB2, CDC25B, DRD2, EGFR, ERBB2, FLT3, GRM1, GRM5, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
5.6426 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.63729 |
|
[BP] GO:0051937 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
5.62567 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.62518 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, RORC, SMAD3, SRC, TRPV1 |
5.56045 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.54472 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, GRM1, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
5.54472 |
|
[BP] GO:0015893 |
None
|
ABCB1, CA2, CHRM5, DRD1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
5.52638 |
|
[BP] GO:0001659 |
None
|
ADORA1, ADRB1, ADRB2, DRD1, DRD2, TRPV1 |
5.50017 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, KDR, PRKCD, PRKCE, SRC |
5.49047 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, ADRB2, APP, AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MET, MMP12, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
5.47878 |
|
[BP] GO:0032409 |
None
|
ABCB1, ADRB2, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCD, PRKCE, PTAFR |
5.42537 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, GRM5, MIF, PRKCD, PTAFR |
5.38322 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PTGES, PTGS1, PTGS2 |
5.38193 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.35564 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.35564 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, GBA2, PTAFR, SOAT1, SOAT2, TYR |
5.33822 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.30864 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, ADRB1, ADRB2, AKR1B1, DRD1, DRD2, MET, PIK3CA, TRPV1 |
5.30531 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, ADRB2, APP, AURKB, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, PPARA, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
5.26882 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.24221 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRB1, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.23956 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, KIT, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
5.15874 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, ADRB2, AKR1B1, ALPL, AOX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.09791 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRB2, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.09612 |
|
[BP] GO:0051234 |
None
|
ABCB1, ACHE, ADORA1, ADRB2, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM1, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, KIT, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TERT, TNKS, TRPV1, XDH |
5.09612 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, KDR, MET, MIF, MMP12, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, SMAD3, TEK |
5.09426 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.09053 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRB1, ADRB2, APP, CA2, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, INSR, PIK3CA, PIK3CB, PTAFR, SRC |
5.06492 |
|
[BP] GO:0007190 |
None
|
ADORA3, ADRB1, ADRB2, DRD1, DRD5, PRKCA |
5.05723 |
|
[BP] GO:0010038 |
response to metal ion
|
APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, KIT, MMP9, PTGES, PTGS2, TERT |
5.03799 |
|
[BP] GO:0006855 |
None
|
ABCB1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.91771 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DRD3, DUSP3, DYRK1A, ESR1, HSPA1A, IGF1R, MET, MIF, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
4.89299 |
|
[BP] GO:0051179 |
None
|
ABCB1, ACHE, ADORA1, ADRB2, ALOX5, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM1, CHRM3, CHRM5, DRD1, DRD2, DRD3, EGFR, ESR1, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, KIT, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.89087 |
|
[BP] GO:0015844 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
4.87986 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.87986 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TERT, TNKS, TOP2A |
4.87986 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CACNA1C, CHRM1, DRD2, DRD3, EGFR, ERBB2, HCAR2, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.86705 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.85437 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
4.83697 |
|
[BP] GO:0030817 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
4.8336 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, GRM5, INSR, KIT, PTGS2 |
4.82184 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, DRD2, DRD5, EGFR, ERBB2, PPARA, SMAD3 |
4.82 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, BCL2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.81985 |
|
[BP] GO:0022898 |
None
|
ABCB1, ADRB2, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE, PTAFR |
4.80058 |
|
[BP] GO:0090257 |
None
|
ADORA1, ADRB2, CACNA1C, CHRM1, CHRM2, CHRM3, KIT, PRKCA, PTAFR, PTGS2, SMAD3 |
4.80058 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, APP, AXL, BCL2, CA2, CDK6, CYP19A1, DRD2, DUSP3, ERBB2, ESR1, ESRRA, HCAR2, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC |
4.76661 |
|
[BP] GO:0042391 |
None
|
ADORA1, ADRB2, APP, BCL2, CACNA1C, DRD1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
4.76272 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, APP, AXL, BCL2, CA2, CACNA1C, CDK6, CHRM1, CHRM2, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, KIT, MMP9, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
4.76272 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
4.75951 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, KIT, MIF, PRKCD, PRKCE, PTPN1, SRC |
4.75228 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, CHRM1, CHRM2, CHRM3, DRD2, EGFR, PTAFR, PTGS2, SLC1A1 |
4.73391 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, MIF, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
4.73391 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
4.722 |
|
[BP] GO:0051098 |
regulation of binding
|
ADRB2, APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TERT, TNKS |
4.722 |
|
[BP] GO:0006810 |
None
|
ABCB1, ACHE, ADORA1, ADRB2, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM1, CHRM3, CHRM5, DRD1, DRD2, DRD3, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, KIT, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TNKS, TRPV1, XDH |
4.71938 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, ADRB2, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
4.71406 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.71134 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ADRB2, APP, AURKB, AXL, BCL2, DNMT1, DRD2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.70884 |
|
[BP] GO:1900542 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, ESRRB, GRM3, GRM8, INSR, PPARA, PRKCA |
4.70884 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, PRKCD, SRC, TEK |
4.70798 |
|
[BP] GO:0007611 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, INSR, KIT, PRKCG, PTGS2 |
4.69308 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, GRM1, GRM5, INSR, KIT, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
4.68657 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRB2, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SOAT1, SRC, TEK, XDH |
4.66037 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, PRKCA, TERT |
4.64702 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, MIF, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
4.64702 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRB2, BCL2, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
4.63266 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
CHRM5, FABP3, FLT3, KIT, PRKCD, SRC, TEK |
4.62017 |
|
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PPARA, PTGES, PTGS1, PTGS2 |
4.61449 |
|
[BP] GO:0006140 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, ESRRB, GRM3, GRM8, INSR, PPARA, PRKCA |
4.59606 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.55325 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTAFR, PTGS2, TERT |
4.46581 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
4.39208 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, NQO2, PTGS1, RORC |
4.38343 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, ADRB2, DUSP3, EGFR, ERBB2, FLT3, GRM1, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
4.36221 |
|
[BP] GO:0043393 |
regulation of protein binding
|
ADRB2, APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC, TERT |
4.33307 |
|
[BP] GO:0030814 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
4.33083 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, ADRB2, DRD2, EGFR, GRM1, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.32962 |
|
[BP] GO:0034762 |
None
|
ABCB1, ADRB2, APP, BCL2, CA2, CACNA1C, DRD1, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE, PTAFR |
4.32855 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CHRM5, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.30549 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, DRD1, PRKCA, PRKCB, PRKCD |
4.28644 |
|
[BP] GO:0006937 |
None
|
ADORA1, ADRB2, CACNA1C, CHRM1, CHRM2, CHRM3, KIT, PTAFR, PTGS2 |
4.26811 |
|
[BP] GO:0030802 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
4.25386 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, CHRM1, DRD2, EGFR, ERBB2, HCAR2, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
4.24677 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, SRC |
4.24532 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, MIF, MMP12, PRKCE, PTAFR, SRC, TRPV1 |
4.24379 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, GRM1, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
4.23438 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTAFR, PTGES, PTGS2, SRC |
4.22724 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.21542 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
4.20175 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CACNA1C, CHRM1, DRD2, DRD3, EGFR, ERBB2, HCAR2, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.19832 |
|
[BP] GO:0001516 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.19676 |
|
[BP] GO:0046457 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.19676 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
BCL2, CDK6, CYP1B1, DUSP3, ERBB2, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, SMAD3, SRC, TEK |
4.1842 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
4.17389 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AURKB, CSNK2A1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, IGF1R, MIF, MMP12, MMP9, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.17389 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
4.11919 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
4.11851 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
APP, DRD2, DUSP3, EGFR, ERBB2, KDR, MIF, PRKCA, PTPN1, SRC, TEK |
4.09951 |
|
[BP] GO:0060359 |
None
|
DRD1, DRD2, DRD3, DRD5, PRKCE, PRKCG, PTAFR |
4.08011 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.06838 |
|
[BP] GO:0032412 |
None
|
ABCB1, ADRB2, APP, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE, PTAFR |
4.06057 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, CHRM1, CHRM3, DRD2, F10, F3, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
4.05025 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.0233 |
|
[BP] GO:1900371 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
4.0233 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2, PRKCE |
4.02262 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
4.02209 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ADRB2, AURKB, BCL2, DNMT1, DRD3, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.0075 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CYP1B1, F3, KDR, KIT, PRKCA, PRKCB, PTGS2, TEK, TERT |
4.00738 |
|
[BP] GO:0030808 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
4.00411 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, ADRB2, ALPL, APP, AXL, BCL2, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ERBB2, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, KDR, KIT, MET, MIF, MMP2, MMP9, PRKCD, PTGS2, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TOP2A |
4.00411 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, BCL2, CACNA1C, CHRM1, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, HCAR2, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.97852 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.95202 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CACNA1C, CHRM1, DRD2, DRD3, EGFR, ERBB2, HCAR2, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.92499 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, CHRM1, DRD2, EGFR, ERBB2, HCAR2, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.91554 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, CSNK2A1, CYP19A1, CYP1A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2 |
3.91279 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, ADRB2, EGFR, ERBB2, FLT3, GRM1, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
3.88535 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.88293 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.88274 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRB1, ADRB2, CACNA1C, DRD1, DRD2, DRD3, DRD5, EGFR, GRM5, KDR |
3.86562 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.84374 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
3.84374 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, MIF, PRKCE, TERT, TNKS |
3.80685 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, PRKCG, RORC, TOP2A |
3.79963 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRB1, ADRB2, APP, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F3, INSR, KDR, KIT, MIF, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
3.77275 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2, DRD5, PTGS2 |
3.77021 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, DRD3, GPR35, MMP9, PRKCE, PTGS2 |
3.76587 |
|
[BP] GO:0030799 |
None
|
ADRB1, DRD1, DRD2, DRD3, DRD5, GRM3, GRM8, PRKCA |
3.74578 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CHRM1, CHRM5, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, GRM1, GRM5, GRM8, INSR, KIT, PRKCG, PTGS2, TRPV1, TYR |
3.74578 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, EGFR, HSPA1A, IGF1R, MET, MIF, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, TERT, XDH |
3.74091 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
3.73609 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX5, MIF, PTGES, PTGS1, PTGS2 |
3.73609 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.71193 |
|
[BP] GO:0040008 |
regulation of growth
|
ADRB1, ADRB2, APP, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ERBB2, ESR2, HSPA1A, INSR, PIK3CA, PIM1, SMAD3, TNKS2 |
3.71121 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRB1, ADRB2, CHRM1, CHRM3, DRD1, DRD5, EGFR, PRKCD, PRKCE, PTAFR, PTGS2 |
3.68594 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
3.67868 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.671 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ADRB2, ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.66889 |
|
[BP] GO:0009410 |
None
|
DRD1, DRD2, DRD3, DRD5, EGFR, PRKCE, PRKCG, PTAFR |
3.66803 |
|
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, SRC |
3.63394 |
|
[BP] GO:0038128 |
None
|
EGFR, ERBB2, PIK3CA, PRKCA, SRC |
3.63224 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, ADRB2, MMP1, MMP12, MMP2, MMP9, TRPV1 |
3.59909 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.59909 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ADRB2, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.57681 |
|
[BP] GO:0036211 |
protein modification process
|
ADRB2, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.57681 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.55144 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.55144 |
|
[BP] GO:1900543 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA, PRKCA |
3.53817 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, DRD5, KIT |
3.53817 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.53742 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.53742 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
3.51887 |
|
[BP] GO:0048167 |
None
|
ADORA1, APP, DRD1, DRD2, DRD5, GRM5, KIT, PTGS2 |
3.51887 |
|
[BP] GO:0007189 |
None
|
ADRB1, ADRB2, DRD1, DRD2, DRD3, DRD5 |
3.5096 |
|
[BP] GO:0045980 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA, PRKCA |
3.5096 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, EGFR, HSPA1A |
3.50832 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTAFR, PTGS2, SRC |
3.50307 |
|
[BP] GO:0043412 |
macromolecule modification
|
ADRB2, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, DNMT1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.4749 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.4711 |
|
[BP] GO:1901653 |
cellular response to peptide
|
ADRB2, AKR1B1, APEX1, APP, GRM5, IGF1R, INSR, PRKCD, SRC |
3.4711 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ADRB2, APP, AURKB, AXL, BCL2, CSNK2A1, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, GRIK5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PIK3CB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.42775 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CYP1B1, ERBB2, F3, KDR, KIT, PRKCA, PRKCB, PTGS2, TEK, TERT, XDH |
3.4059 |
|
[BP] GO:0030818 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.40339 |
|
[BP] GO:0046903 |
None
|
ALOX5, APP, AXL, CA2, CA9, CHRM1, CHRM3, CHRM5, DRD2, DRD3, HSPA1A, KIT, MIF, MMP9, PRKCD, PTAFR, SLC1A1, SLC22A2, TRPV1, XDH |
3.38915 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.35823 |
|
[BP] GO:0045761 |
None
|
DRD2, DRD3, DRD5, GRM3, PRKCA |
3.35823 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK |
3.34559 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, PRKCE, TERT |
3.34548 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, TYR |
3.33021 |
|
[BP] GO:0030803 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.31515 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, PTAFR, PTGS2, SRC |
3.30706 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
3.29721 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.28717 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, BCL2, CACNA1C, CHRM1, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ERBB2, GRIK5, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.28709 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, MIF, PPARA, PRKCD, SMAD3, TEK |
3.28643 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.27591 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
3.26723 |
|
[BP] GO:0095500 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.25158 |
|
[BP] GO:1903831 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.25158 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ADRB2, ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CHRM3, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.2484 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, DRD5, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, KIT, MMP2, MMP9, PTAFR, PTGS2, SRC, TOP2A |
3.2484 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
ADRB2, APP, AURKB, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTAFR, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A |
3.24575 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, KIT |
3.23853 |
|
[BP] GO:0030815 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.23853 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, MMP12, PPARA, PRKCD, SMAD3, TEK |
3.22823 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
CACNA1C, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, PRKCE, SMAD3, TRPV1 |
3.22168 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, KIT, PTGS2, TYR |
3.22168 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.22168 |
|
[BP] GO:0031649 |
None
|
ADRB1, ADRB2, TRPV1 |
3.22168 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.22168 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, ADRB1, ADRB2, APEX1, APP, AURKB, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GRM3, GRM8, HSPA1A, IGF1R, INSR, KIT, MET, MMP12, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCG, PTAFR, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.20668 |
|
[BP] GO:1900372 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.2038 |
|
[BP] GO:0030809 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.2038 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, KIT, PRKCD, PTAFR, PTGS2 |
3.20146 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.19243 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
3.16863 |
|
[BP] GO:0097755 |
None
|
ADRB1, ADRB2, DRD1, EGFR, PTAFR |
3.16636 |
|
[BP] GO:0030800 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.16636 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CACNA1C, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, MIF, MMP12, PRKCA, PRKCE, PTAFR, SRC, TRPV1 |
3.16466 |
|
[BP] GO:0034765 |
None
|
ABCB1, ADRB2, APP, CACNA1C, DRD1, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE, PTAFR |
3.14472 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, PTAFR, PTGS2, TERT |
3.1345 |
|
[BP] GO:0048169 |
None
|
APP, DRD2, GRM5, KIT |
3.12666 |
|
[BP] GO:0071702 |
None
|
ABCB1, ADORA1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM5, DRD1, DRD2, DRD3, FABP3, MMP12, PPARA, PRKCB, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SOAT1, SOAT2, TNKS, TRPV1 |
3.12659 |
|
[BP] GO:0015850 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3, SOAT1, SOAT2 |
3.11511 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC, TERT |
3.0959 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
3.0959 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.0959 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.09234 |
|
[BP] GO:0050994 |
None
|
ADORA1, HCAR2, PPARA, PRKCD, PRKCE |
3.09234 |
|
[BP] GO:0010359 |
None
|
ABCB1, GRM5, PTAFR |
3.07099 |
|
[BP] GO:0002024 |
None
|
ADRB1, ADRB2, TRPV1 |
3.07099 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, AXL, KIT, MIF, PIK3CA, PIK3CB, PTAFR, PTGES, PTGS1, PTGS2, TRPV1 |
3.0702 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.0702 |
|
[BP] GO:0001975 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.0702 |
|
[BP] GO:0006693 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
3.0702 |
|
[BP] GO:0006692 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
3.0702 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.07 |
|
[BP] GO:0043270 |
None
|
ABCB1, ADORA1, ADRB2, CHRM1, DRD1, DRD2, MIF, PRKCD, PTAFR |
3.06867 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, KIT |
3.06323 |
|
[BP] GO:0015696 |
None
|
CHRM5, DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.06323 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, KDR, KIT, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, SRC, TEK |
3.01496 |
|
[BP] GO:0007271 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.00974 |
|
[BP] GO:1904646 |
cellular response to amyloid-beta
|
ADRB2, APP, GRM5, IGF1R |
3.00974 |
|
[BP] GO:0043279 |
None
|
DRD2, DRD3, DRD5, PRKCE, PRKCG, TRPV1 |
3.00486 |
|
[BP] GO:0019933 |
None
|
ADRB1, ADRB2, DRD1, DRD2, DRD3, DRD5 |
3.00486 |
|
[BP] GO:0030258 |
lipid modification
|
CYP1A1, EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB, SOAT1, SOAT2 |
3.00486 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRB1, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GRM3, GRM5, GRM8, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.00243 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
2.97549 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CACNA1C, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, MIF, MMP12, PRKCA, PRKCE, PTAFR, SRC |
2.96269 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, KIT, MMP9, TERT |
2.95459 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.95224 |
|
[BP] GO:0050873 |
None
|
ADRB1, ADRB2, FABP4, PTGS2 |
2.95224 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
ADRB1, ADRB2, APP, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, TNKS2 |
2.9395 |
|
[BP] GO:0007191 |
None
|
DRD1, DRD3, DRD5 |
2.93949 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.93949 |
|
[BP] GO:0045934 |
None
|
APEX1, AURKB, DNMT1, DRD2, DRD3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, MMP12, PPARA, PRKCA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
2.93735 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTAFR, PTGS2 |
2.93609 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.93219 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CACNA1C, DRD2, DRD3, EGFR, HCAR2, MIF, MMP12, PRKCA, PRKCE, SRC |
2.92754 |
|
[BP] GO:0072347 |
None
|
DRD2, DRD3, DRD5, PRKCE, PRKCG |
2.92573 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.92573 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, GRIK5, HCAR2, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.91979 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
MIF, PTGES, PTGS1, PTGS2 |
2.89948 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, GRIK5, HCAR2, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.87561 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, MIF, MMP12, PRKCE, SRC |
2.85723 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.85723 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
2.85509 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
APP, DRD2, EGFR, KDR, MIF, PRKCA, SRC, TEK |
2.84877 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, ADRB1, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GRM3, GRM5, GRM8, HSPA1A, IGF1R, INSR, KIT, MET, MMP12, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.84805 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.84805 |
|
[BP] GO:1904645 |
response to amyloid-beta
|
ADRB2, APP, GRM5, IGF1R |
2.84805 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, BCL2, CDK6, CYP1B1, DRD2, ERBB2, FABP3, HSPA1A, PTGES, PTGS2, SMAD3, TERT, XDH |
2.83303 |
|
[BP] GO:0019229 |
None
|
CHRM1, CHRM3, EGFR, PTAFR, PTGS2 |
2.83018 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.8279 |
|
[BP] GO:0046854 |
phosphatidylinositol phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.8279 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.8279 |
|
[BP] GO:0019371 |
None
|
PTGES, PTGS1, PTGS2 |
2.8279 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.8279 |
|
[BP] GO:0046960 |
None
|
DRD1, DRD5 |
2.8279 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.8279 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
2.8279 |
|
[BP] GO:0019935 |
None
|
ADRB1, ADRB2, DRD1, DRD2, DRD3, DRD5 |
2.81199 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.8111 |
|
[BP] GO:0031279 |
None
|
DRD2, DRD3, DRD5, GRM3, PRKCA |
2.8111 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
ERBB2, IGF1R, PIK3CA, PIK3CB, PTAFR |
2.8111 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
ERBB2, IGF1R, PIK3CA, PIK3CB |
2.80985 |
|
[BP] GO:0045744 |
None
|
ADRB2, DRD2, DRD3, MET |
2.80985 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
2.78046 |
|
[BP] GO:0051339 |
None
|
DRD2, DRD3, DRD5, GRM3, PRKCA |
2.78046 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, DRD5, EGFR |
2.77018 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, ERBB2, F3, KDR, MMP12, PRKCA, SMAD3, TEK, XDH |
2.76326 |
|
[BP] GO:1903829 |
positive regulation of cellular protein localization
|
APP, BCL2, CHRM1, EGFR, ERBB2, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TERT |
2.76326 |
|
[BP] GO:0007194 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.76058 |
|
[BP] GO:0043278 |
None
|
DRD2, DRD3, PRKCE, PRKCG |
2.76058 |
|
[BP] GO:0014072 |
None
|
DRD2, DRD3, PRKCE, PRKCG |
2.76058 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, CSNK2A1, DRD2, EGFR, ERBB2, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
2.72797 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.72521 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
ERBB2, IGF1R, PIK3CA, PIK3CB, PTAFR |
2.72162 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.71238 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.71238 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
EGFR, ESR1, KIT, PTAFR |
2.71238 |
|
[BP] GO:0022600 |
None
|
CHRM1, CHRM3, CHRM5, DRD3, SOAT2 |
2.69192 |
|
[BP] GO:0051100 |
negative regulation of binding
|
ADRB2, AURKB, CYP2D6, MET, PPARA, PRKCD, TNKS |
2.68165 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
2.67521 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.66584 |
|
[BP] GO:0045987 |
None
|
CHRM3, KIT, PTAFR, PTGS2 |
2.66443 |
|
[BP] GO:0031280 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.66443 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.63468 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
2.63468 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.63468 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
2.62715 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.62715 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.62715 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
CA2, CA7, PRKCE |
2.62715 |
|
[BP] GO:0060158 |
None
|
DRD1, DRD2, DRD5 |
2.62715 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
2.62715 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR |
2.6216 |
|
[BP] GO:0032465 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.60944 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F3, FABP4, KDR, MET, MIF, PRKCA, PTGS2, SMAD3 |
2.60726 |
|
[BP] GO:0010628 |
positive regulation of gene expression
|
ADRB2, APP, DNMT1, DRD1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, INSR, KIT, MET, MMP12, PIK3CB, PPARA, PTAFR, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.60103 |
|
[BP] GO:0046834 |
lipid phosphorylation
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.58881 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.58174 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, GRIK5, HCAR2, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.57978 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
EGFR, ESR1, KIT, PTAFR |
2.57813 |
|
[BP] GO:0051350 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.57813 |
|
[BP] GO:0050776 |
regulation of immune response
|
BCL2, DRD2, DUSP3, ESR1, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC |
2.56532 |
|
[BP] GO:0050708 |
None
|
ACHE, CACNA1C, DRD2, DRD3, EGFR, HCAR2, MIF, MMP12, PRKCA, PRKCE, SRC |
2.56359 |
|
[BP] GO:1903524 |
None
|
ADRB1, EGFR, PTAFR, PTGS2, SLC1A1 |
2.55588 |
|
[BP] GO:0045321 |
leukocyte activation
|
ALOX5, AXL, BCL2, FLT3, FUT7, HSPA1A, KIT, MIF, MMP9, PRKCB, PRKCD, PRKCE, PTAFR, RORC, SMAD3, TRPV1 |
2.5523 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.53673 |
|
[BP] GO:1990845 |
None
|
ADRB1, ADRB2, TRPV1 |
2.53673 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.53673 |
|
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.53673 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.53402 |
|
[BP] GO:0010959 |
None
|
ADORA1, ADRB2, BCL2, CACNA1C, DRD1, DRD2, DRD3, GPR35, PRKCE, PTGS2 |
2.53238 |
|
[BP] GO:1904062 |
None
|
ADRB2, APP, CACNA1C, DRD1, DRD2, DRD3, GPR35, MMP9, PRKCE |
2.52582 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, HCAR2, MIF, MMP12, PRKCE, PTAFR, SRC |
2.52366 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, PPARA, PRKCD, SMAD3, TEK |
2.51568 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.50544 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
2.50474 |
|
[BP] GO:0014075 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.49729 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.49729 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.47533 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.45174 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, KIT, PTGS2, SRC |
2.43981 |
|
[BP] GO:0006357 |
None
|
ADRB2, APP, AURKB, CA9, DNMT1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GLO1, HSPA1A, KIT, MET, MMP12, PPARA, PRKCB, PTAFR, RORC, SMAD3, TERT, TNKS, TOP2A, TRPV1 |
2.43768 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CYP1A1, MIF, PRKCD, PTGS2, TERT |
2.43462 |
|
[BP] GO:0032413 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.42951 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AURKB, CSNK2A1, DNMT1, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, HSPA1A, IGF1R, KDR, MIF, MMP12, MMP9, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.42494 |
|
[BP] GO:0045765 |
regulation of angiogenesis
|
CYP1B1, ERBB2, F3, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
2.42494 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, GRM5, KIT, MIF, PTPN1, SRC |
2.42062 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.42062 |
|
[BP] GO:0034435 |
None
|
SOAT1, SOAT2 |
2.42062 |
|
[BP] GO:0034433 |
None
|
SOAT1, SOAT2 |
2.42062 |
|
[BP] GO:0034434 |
None
|
SOAT1, SOAT2 |
2.42062 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.42062 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.42062 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.42062 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.42062 |
|
[BP] GO:0002025 |
None
|
ADRB1, ADRB2 |
2.42062 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
2.41638 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
ADRB2, CSNK2A1, ESRRB, HSPA1A, INSR, KDR, PIK3CB, PPARA, PRKCD, PRKCE, PTPN1 |
2.41133 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.40331 |
|
[BP] GO:0050679 |
None
|
EGFR, ERBB2, F3, KDR, MMP12, PRKCA, TEK |
2.40281 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, BCL2, CHRM1, CSNK2A1, EGFR, ERBB2, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.40217 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, HCAR2, MIF, MMP12, PRKCE, SRC |
2.40193 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ADRB2, APP, AXL, BCL2, CA2, CYP1B1, DRD2, ESRRB, F3, INSR, KDR, KIT, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT |
2.39577 |
|
[BP] GO:0042060 |
None
|
DRD5, EGFR, ERBB2, PPARA, SMAD3 |
2.39518 |
|
[BP] GO:0046717 |
None
|
CHRM5, DRD2, DRD3, SLC1A1, TRPV1 |
2.39518 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
ADRB2, APEX1, BCL2, ESRRB, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
2.39158 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.39131 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.39131 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.39131 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.39131 |
|
[BP] GO:0045986 |
None
|
ADORA1, ADRB2, PTGS2 |
2.39131 |
|
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, EGFR, PRKCE, PTAFR, SRC |
2.36518 |
|
[BP] GO:1903793 |
None
|
ABCB1, MIF, PRKCD, PTAFR |
2.35661 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.35198 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, DRD3, GRM1, GRM5, PRKCE |
2.35198 |
|
[BP] GO:0048731 |
system development
|
ACHE, ADORA1, ALPL, CACNA1C, CHRM1, CHRM2, CHRM3, DYRK1A, ERBB2, MMP9, PIK3CA, SMAD3, SRC, TEK |
2.34668 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.33514 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CYP1B1, DRD1, DRD2, EGFR, ERBB2, FUT7, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PTGS2, SRC, TEK |
2.32743 |
|
[BP] GO:0070542 |
None
|
FABP3, PRKCE, PTAFR, PTGS2, SRC |
2.32743 |
|
[BP] GO:1901570 |
None
|
ALOX5, MIF, PTGES, PTGS1, PTGS2 |
2.32743 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.32743 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.32444 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.32435 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.32435 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.32435 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.32009 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.32009 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, DRD3 |
2.31656 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, ERBB2, INSR, KDR, SMAD3, SRC, TRPV1 |
2.29631 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ADRB2, APP, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ERBB2, ESR1, ESRRA, F3, INSR, KDR, KIT, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
2.29536 |
|
[BP] GO:0051336 |
regulation of hydrolase activity
|
ADRB1, APP, CSNK2A1, DRD2, EGFR, ERBB2, ESR1, F3, HSPA1A, KIT, MMP9, NUAK1, PRKCD, PTAFR, PTGS2, PTPN1, SMAD3, SRC, XDH |
2.28775 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, MIF, PIK3CB |
2.28624 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.28624 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.28624 |
|
[BP] GO:0045785 |
positive regulation of cell adhesion
|
CDK6, ERBB2, KDR, PIK3CA, PRKCA, PRKCE, PTAFR, SMAD3, SRC, TEK |
2.27864 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, PPARA, PRKCD, PTGS2, SMAD3, TEK |
2.27139 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
CACNA1C, DRD1, DRD2, ESR1, GPR35, GRM1, PRKCE, TRPV1 |
2.26685 |
|
[BP] GO:0038127 |
None
|
EGFR, ERBB2, PIK3CA, PRKCA, SRC |
2.26623 |
|
[BP] GO:0032410 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.26623 |
|
[BP] GO:1904063 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.26623 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.26001 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.26001 |
|
[BP] GO:0097366 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.26001 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.25611 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.25611 |
|
[BP] GO:0019226 |
None
|
CHRM5, DRD1, DRD5 |
2.25611 |
|
[BP] GO:0051093 |
None
|
ADRB1, ADRB2, APP, BCL2, CDK6, DRD3, EGFR, ERBB2, ESRRB, MIF, PPARA, SMAD3, TEK, TERT, TRPV1, XDH |
2.24709 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.24709 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.24709 |
|
[BP] GO:0046649 |
lymphocyte activation
|
AXL, BCL2, FLT3, FUT7, KIT, PRKCB, PRKCD, RORC, SMAD3 |
2.23236 |
|
[BP] GO:0051241 |
negative regulation of multicellular organismal process
|
ADORA1, ADRB1, ADRB2, APP, AXL, BCL2, CDK6, DRD2, DRD3, EGFR, ERBB2, GPR35, PRKCD, PTGS2, SMAD3, TEK, TERT, XDH |
2.23236 |
|
[BP] GO:0090342 |
None
|
CDK6, MIF, NUAK1, TERT |
2.22792 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.22587 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, HCAR2, HSPA1A, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, SRC |
2.21695 |
|
[BP] GO:0033043 |
regulation of organelle organization
|
ADRB2, AURKB, BCL2, DNMT1, DRD3, GRIK5, HSPA1A, INSR, KDR, MET, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.21185 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.19284 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.19284 |
|
[BP] GO:0007617 |
None
|
APP, DRD1, DRD5 |
2.19284 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.18842 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, DYRK1A, EGFR, PPARA, RORC |
2.18489 |
|
[BP] GO:0071229 |
cellular response to acid chemical
|
DNMT1, EGFR, KDR, MMP2, PRKCE, PTAFR, SRC |
2.17382 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.17382 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.17382 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.17382 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.17382 |
|
[BP] GO:1901529 |
None
|
ABCB1, PTAFR |
2.17382 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.17382 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.17382 |
|
[BP] GO:0006939 |
None
|
CHRM3, DRD1, DRD2, TRPV1 |
2.1707 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, FABP3, FABP4, FUT7, GBA2, HSPA1A, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
2.15676 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, KIT, MMP9, RORC |
2.14246 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.14016 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
EGFR, ESR1, KIT, PTAFR |
2.14016 |
|
[BP] GO:0035588 |
None
|
ADORA1, ADORA3, PTAFR |
2.14016 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3 |
2.14016 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.14016 |
|
[BP] GO:0071880 |
None
|
ADRB1, ADRB2, DRD2 |
2.14016 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ESR1, HSPA1A, KDR, KIT, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.13884 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CACNA1C, CYP19A1, DRD2, EGFR, HCAR2, PRKCA, PRKCE |
2.12572 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CHRM2, CYP1A1, CYP1A2, DRD3, EGFR, HSD11B2, KIT, MMP12, PRKCD, PTAFR, PTGES, PTGS2, SMAD3, SRC, TRPV1, TYR |
2.11241 |
|
[BP] GO:0045933 |
None
|
CHRM3, KIT, PTAFR, PTGS2 |
2.11125 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF |
2.10635 |
|
[BP] GO:0006650 |
glycerophospholipid metabolic process
|
ACHE, CSNK2A1, DRD2, EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.1026 |
|
[BP] GO:0010468 |
regulation of gene expression
|
ADORA3, ADRB2, APEX1, APP, AURKB, BCL2, CA9, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GRM5, HSPA1A, INSR, KDR, KIT, MET, MIF, MMP12, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PTAFR, RORC, SMAD3, SRC, TERT, TNKS, TOP2A, TRPV1, XDH |
2.10085 |
|
[BP] GO:0050808 |
None
|
ACHE, APP, DRD1, DRD2, ERBB2, GRM5 |
2.08808 |
|
[BP] GO:0051302 |
None
|
AURKB, CDC25B, DRD2, DRD3, ESRRB, PRKCE |
2.08808 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.08449 |
|
[BP] GO:1903959 |
None
|
ABCB1, GRM5, PTAFR |
2.08449 |
|
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.08449 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.08449 |
|
[BP] GO:0048168 |
None
|
APP, DRD2, GRM5, KIT |
2.08449 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, DRD2, DRD3, GPR35, HSPA1A, MMP9, PRKCB, PRKCE, PTGS2 |
2.07287 |
|
[BP] GO:0046488 |
phosphatidylinositol metabolic process
|
DRD2, EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
2.06192 |
|
[BP] GO:0048608 |
reproductive structure development
|
AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, KIT, SRC |
2.05955 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.05955 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.05505 |
|
[BP] GO:0034766 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.05505 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, EGFR, ESR1, FLT3, INSR, KIT, PRKCD, PRKCE, SRC |
2.04575 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.03957 |
|
[BP] GO:0090344 |
None
|
CDK6, MIF, TERT |
2.02942 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.02942 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.02942 |
|
[BP] GO:0050996 |
None
|
PPARA, PRKCD, PRKCE |
2.02942 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, KIT, PTGS2, TYR |
2.02851 |
|
[BP] GO:0048146 |
positive regulation of fibroblast proliferation
|
CDK6, EGFR, ESR1, MIF |
2.02851 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.02851 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.02051 |
|
[BP] GO:0051591 |
None
|
APEX1, APP, PTAFR, TEK, TYR |
2.02021 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.02021 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, BCL2, DRD2, HSD11B2 |
2.02021 |
|
[BP] GO:0035303 |
None
|
ADORA1, CHRM5, DRD2, NUAK1, PRKCD, SMAD3 |
2.00701 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, FLT3, KDR, KIT, TEK |
2.00199 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.00199 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
ADRB1, BCL2, DRD1, PRKCG |
2.00199 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.00199 |
|
[BP] GO:0045936 |
None
|
DRD2, DRD3, DUSP3, FABP4, GRM3, GRM8, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
2.00014 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALPL, APP, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F10, F3, FLT3, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TERT, TRPV1 |
12.1016 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ADORA1, ADRB2, CA2, CA4, CA9, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD5, EGFR, ERBB2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, MET, PRKCG, PTGS2, SLC1A1, SLC22A1, SRC, TEK, TRPV1 |
10.6084 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALOX5, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KDR, KIT, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
10.5367 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ADORA1, ADORA3, ADRB1, ADRB2, APP, AXL, BACE1, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, F10, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MET, PRKCG, PTAFR, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
9.68583 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRB1, ADRB2, APP, AXL, BACE1, CA4, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, F10, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
9.67233 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRB1, ADRB2, APP, AXL, BACE1, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
8.27285 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KDR, KIT, MET, PIK3CA, PIK3CB, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TEK, TRPV1, TYR |
8.10567 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, SLC22A2, SRC, TRPV1 |
5.86618 |
|
[CC] GO:0097060 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, TRPV1 |
5.52638 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, F10, FLT3, GBA2, GRIA2, HSD11B1, HSD11B2, HSD17B2, PTGES, PTGS1, PTGS2, PTPN1, SOAT1, SOAT2 |
4.5419 |
|
[CC] GO:0014069 |
None
|
ADORA1, CACNA1C, CHRM1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
4.46352 |
|
[CC] GO:0099572 |
None
|
ADORA1, CACNA1C, CHRM1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
4.46352 |
|
[CC] GO:0031224 |
None
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, ALPL, APP, AXL, BACE1, CA12, CA14, CA4, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD17B2, IGF1R, INSR, KDR, KIT, MET, PTAFR, PTGES, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, TEK, TRPV1, TYR |
4.19371 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, GBA2, GRIA2, HSD11B1, HSD11B2, HSD17B2, PTGES, PTGS1, PTGS2, SOAT1, SOAT2 |
4.12305 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, GRIK5, HSPA1A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SOAT1, SOAT2, XDH |
3.97852 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, CHRM3, EGFR, ERBB2, SLC22A1, TEK |
3.81134 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, ERBB2, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, PTGES, SRC, TNKS2, TYR |
3.76333 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CACNA1C, CDC25B, CDK6, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA2, GRIA4, GRIK5, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, KIT, MIF, MMP2, MMP9, NQO2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.66743 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.62946 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CHRM3, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PIK3CA, PRKCG, PTGS2, SRC, TEK |
3.56912 |
|
[CC] GO:0043235 |
receptor complex
|
ADRB2, APP, EGFR, ERBB2, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
3.50635 |
|
[CC] GO:0016021 |
None
|
ABCB1, ADORA1, ADORA3, ADRB1, ADRB2, ALPL, APP, AXL, BACE1, CA12, CA14, CA9, CACNA1C, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD17B2, IGF1R, INSR, KDR, KIT, MET, PTAFR, PTGES, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, TEK, TRPV1, TYR |
3.48726 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A2, SLC47A1, SMAD3, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.48237 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CHRM3, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PIK3CA, PRKCG, PTGS2, SRC, TEK |
3.4749 |
|
[CC] GO:0045211 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, GRIA2, GRIA4, GRIK5, GRM3, TRPV1 |
3.42377 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, BACE1, CA2, CHRM1, CHRM2, CHRM3, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PRKCG, PTGS2, SRC |
3.30751 |
|
[CC] GO:0098793 |
None
|
ADORA1, APP, CHRM1, CHRM2, CHRM3, DRD2, GRIK5, SLC22A2 |
3.3075 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.22168 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ACHE, ADORA1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CACNA1C, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A2, SLC47A1, SMAD3, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.20987 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, BACE1, CA2, CACNA1C, CHRM1, CHRM2, CHRM3, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, PRKCG, PTGS1, PTGS2, SLC22A2, SRC, TRPV1 |
3.0702 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CHRM3, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM3, INSR, PTGS1, SRC, TRPV1 |
2.8559 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CHRM3, DRD1, DRD2, DRD5, GRIA2, GRIA4, GRIK5, GRM3, INSR, PTGS1, SRC, TRPV1 |
2.8559 |
|
[CC] GO:0042734 |
None
|
GRIK5, GRM1, GRM3, GRM5, GRM8 |
2.78046 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.45914 |
|
[CC] GO:0044309 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.4248 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, DRD5, INSR, SRC, TRPV1 |
2.27385 |
|
[CC] GO:0031982 |
None
|
ABCB1, ADRB1, ADRB2, AKR1B1, AKR1B10, ALPL, AOX1, APP, AXL, BACE1, CA1, CA2, CA4, CA6, DRD2, DRD3, DUSP3, EGFR, F3, FABP3, FABP4, GLO1, GRIA4, GRM5, HSPA1A, INSR, KDR, KIT, MIF, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, PTPN1, SLC1A1, SLC22A2, SLC47A1, SRC, TYR |
2.22587 |
|
[CC] GO:0030054 |
cell junction
|
ACHE, AKR1B1, APP, CHRM1, CHRM2, CHRM3, CHRM5, EGFR, GRIA2, GRIA4, GRIK5, HCAR2, HSPA1A, KDR, KIT, PRKCD, PRKCG, TEK, TRPV1 |
2.22442 |
|
[CC] GO:0045202 |
None
|
ACHE, APP, CHRM1, CHRM2, CHRM3, CHRM5, EGFR, GRIA2 |
2.15315 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.14016 |
|
[CC] GO:0031090 |
None
|
ADRB2, ALOX5, APP, BACE1, BCL2, CA4, CHRM2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD5, EGFR, ERBB2, FUT7, GBA2, GRIA2, GRIA4, INSR, PRKCA, PTAFR, PTGS1, PTGS2, SMAD3, SRC, TNKS, TNKS2, TYR |
2.02921 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PIM1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
16.9617 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDK6, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
16.0982 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.1332 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DUSP3, DYRK1A, EGFR, ERBB2, F10, F3, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
14.7123 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
12.9411 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CDK6, CHRM1, CHRM2, CHRM3, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
12.6551 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
11.7035 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, PPARA, PRKCE, PTAFR, RORC, SMAD3, TEK, TRPV1 |
11.5203 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
11.5203 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CHRM3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.3096 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
10.2334 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GRIA2, GRIA4, GRIK5, GRM1, GRM5 |
10.1142 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK, TRPV1 |
10.1142 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRB1, ADRB2, AXL, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, EGFR, ERBB2, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK, TRPV1 |
10.1142 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.36681 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.32169 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
8.84858 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
8.3917 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.88548 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.69912 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
7.68423 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
7.6524 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6 |
7.48017 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.37766 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
7.0038 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, ERBB2, INSR, KDR, KIT |
6.80547 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B2, HSD17B1, NQO2, PTGES, PTGS1, PTGS2, SOAT1, SOAT2, SRC, XDH |
6.71987 |
|
[MF] GO:1901338 |
None
|
ADRB1, ADRB2, DRD1, DRD2, DRD3, DRD5 |
6.59461 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
6.59461 |
|
[MF] GO:0005496 |
steroid binding
|
ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC, SOAT1, SOAT2 |
6.36488 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TERT |
6.35623 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.32065 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
6.23507 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, ERBB2, FABP3, FABP4, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SOAT1, SOAT2, SRC, TEK, TOP2A, TRPV1, XDH |
6.23209 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
6.2029 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
6.09873 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
6.05655 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
5.78279 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, F10, F3, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, SLC1A1, SOAT1, SOAT2, SRC, TEK, TOP2A, TRPV1, XDH |
5.72 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.48093 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TYR |
5.35263 |
|
[MF] GO:0008227 |
None
|
ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, DRD2 |
5.24731 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, XDH |
5.23534 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
5.05874 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRB1, ADRB2, APP, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRB, F3, GRM5, HSPA1A, KIT, MET, MIF, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
4.99452 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
4.91914 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, ERBB2, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
4.90233 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, ERBB2, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
4.89892 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.86783 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.81985 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, ADRB2, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ERBB2, ESR1, ESR2, FLT3, GRIK5, IGF1R, KDR, KIT, MET, MIF, MMP9, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
4.76272 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
4.59891 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.38505 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.38505 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.33083 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.21542 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.19676 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, CHRM3, EGFR, HSD17B1, IGF1R, INSR, NQO2 |
4.17389 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ADORA1, ADRB1, ADRB2, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
4.16646 |
|
[MF] GO:0008289 |
lipid binding
|
AXL, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, PTAFR, RORC, SOAT1, SOAT2, TRPV1 |
4.12855 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
3.95905 |
|
[MF] GO:0015238 |
None
|
ABCB1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.90813 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
3.90257 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRB1, ADRB2, CHRM1, CHRM2, CHRM3, CHRM5, DRD1, DRD2, DRD3, DRD5, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, PTAFR |
3.88573 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
3.87335 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.70194 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
3.64588 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.6008 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.6008 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ACHE, ADORA1, ADORA3, ADRB1, ADRB2, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CHRM1, CHRM2, CHRM3, CHRM5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DRD5, DUSP3, DYRK1A, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.59243 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CDK6, CSNK2A1, DYRK1A, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
3.52978 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.49087 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, CHRM3, DRD1, DRD2, DRD3, DRD5 |
3.48145 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, ERBB2, KIT, MET, PIK3CA, PIK3CB |
3.4518 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, BACE1, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, ERBB2, F10, F3, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
3.36574 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ADORA1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, SRC, TEK, TOP2A, TRPV1 |
3.34414 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
ADRB1, EGFR, ERBB2, INSR, KDR, KIT, SMAD3 |
3.2484 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.19485 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.16863 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, ERBB2, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.16466 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.07099 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.07099 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.00974 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.89948 |
|
[MF] GO:0004629 |
None
|
ADORA1, CHRM1, CHRM3, CHRM5 |
2.84805 |
|
[MF] GO:0001540 |
amyloid-beta binding
|
ACHE, ADRB2, BACE1, GRIA2, INSR |
2.83018 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.8279 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.8279 |
|
[MF] GO:0034736 |
None
|
SOAT1, SOAT2 |
2.8279 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.8279 |
|
[MF] GO:0004772 |
None
|
SOAT1, SOAT2 |
2.8279 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.8279 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.8279 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.8279 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, ADRB2, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.81597 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, ADRB2, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.7465 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.72521 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.64538 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, ERBB2, MET, PPARA, PTPN1, SMAD3 |
2.54665 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM3, CHRM5 |
2.49729 |
|
[MF] GO:0016740 |
transferase activity
|
AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, ERBB2, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2 |
2.47715 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.44022 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.42062 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.42062 |
|
[MF] GO:0004939 |
None
|
ADRB1, ADRB2 |
2.42062 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.42062 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.42062 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.42062 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.42062 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.42062 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ACHE, ADORA1, ADRB1, ADRB2, AOX1, AXL, BCL2, DRD2, EGFR, ERBB2, FLT3, KIT, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TYR, XDH |
2.41919 |
|
[MF] GO:0004935 |
None
|
ADRB1, ADRB2, DRD2 |
2.39131 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ACHE, ADRB2, AOX1, BCL2, DRD2, FLT3, KIT, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TYR, XDH |
2.33889 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.32009 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.28933 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, ERBB2, IGF1R, INSR, KDR, TEK |
2.27385 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.19284 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.19284 |
|
[MF] GO:0001588 |
None
|
DRD1, DRD5 |
2.17382 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.17382 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.17382 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.17382 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.1707 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PRKCB, SMAD3, SRC |
2.16966 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.14016 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, PRKCB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.11241 |
|
[MF] GO:0008081 |
None
|
ADORA1, APEX1, CHRM1, CHRM3, CHRM5 |
2.11122 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, PRKCB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.08449 |
