TCM-ID Component

Description of the Component

Component ID	TCMH289
Latin Name	Cyathula officinalis
English Name	Mediinal cyathula
Chinese Pinyin Name	Chuan Niu Xi
中文名	川牛膝
TCM Properties	Mild,Sweet,Sour,Bitter
TCM Meridians	Liver,Kidney
Therapeutic Class English	Blood activation and stasis removal
Therapeutic Class Chinese	活血化淤
Functions	eliminate blood stasis and stimulate menstrual discharge, allay arthralgia and ease the joint, and relieve urinary disturbance
Toxicity	NA
Geo-authentic habitats (道地产区)	Sichuan Province,Chongqing
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAF2788-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2937	A Wei She Xiang Hua Ji Ointment	阿魏麝香化积膏
TCMFx2918	An Kun Zan Yu Pills	安坤赞育丸
TCMFx2955	An Yang Gu Ben Ointment	安阳固本膏
TCMF2963	An Yang Hu Gu Yao Wine	安阳虎骨药酒
TCMFx2172	Ankun Zanyu Pills	安坤赞育丸
TCMFx6944	Ba Zi Bu Shen Capsules	八子补肾胶囊
TCMF3002	Bai Feng Yin	白凤饮
TCMFx3509	Bao Gu Mu Gua Wine	豹骨木瓜酒
TCMF3501	Bao Gu Wine	豹骨酒
TCMF2281	Blood Revitalizing and Ruo Opening Decoction	活血通络汤
TCMF2062	Bolus as Kidney-Yin-Tonic; Kidney-yin-Tonifying Bolus	左归丸
TCMF1349	Brain-Invigorating and Kidney-Tonifying Pill	健脑补肾丸
TCMF2214	Brain-Invigorating and Kidney-Tonifying Pill	健脑补肾丸
TCMFx878	Chuan Long Gu Ci Tablet	穿龙骨刺片
TCMFx3428	Chuan Long Gu Ci Tablets	穿龙骨刺片
TCMFx1966	Combination LGT Fries Recipe	复方雷公藤煎剂
TCMF3700	Da Hu Zhuang Yuan Pills	打虎壮元丸
TCMF3696	Du Huo Ji Sheng Recipe	独活寄生合剂
TCMF829	Du Huo Ji Sheng Recipe	独活寄生合剂
TCMF3799	Du Zhong Yao Wine	杜仲药酒
TCMFx1857	EZLP Decoction	二术苓皮汤
TCMF3375	Feng Shi Gao Yao	风湿膏药
TCMF3432	Feng Shi Wine	风湿酒
TCMF3582	Feng Tong Ning Tablets	风痛宁片
TCMF3756	Fu Bao Jin Pills	妇宝金丸
TCMFx28	Fu Fang Dian Ji Xue Teng Ointment	复方滇鸡血藤膏
TCMF3117	Fu Gui Feng Shi Ointment	附桂风湿膏
TCMF3813	Fu Kang Pills	妇康丸
TCMFx3886	Fu Ke Ning Kun Pills	妇科宁坤丸
TCMFx7240	Fu Ning Capsules	妇宁胶囊
TCMFx3037	Fu Ning Pills	妇宁丸
TCMFx1862	GFYL Decoction	桂附益苓汤
TCMFx4695	Hu Gu Zhui Feng Wine	虎骨追风酒
TCMFx1109	Hua Mo Yan Capsule	滑膜炎胶囊
TCMFx4873	Hua Mo Yan Granules	滑膜炎颗粒
TCMFx1110	Hua Mo Yan Granules	滑膜炎颗粒
TCMFx94	Hua Mo Yan Tablets	滑膜炎片
TCMFx4471	Huo Xue Zhuang Jin Pills	活血壮筋丸
TCMFx4462	Huo Xue Zhuang Jin Pills	活血壮筋丸
TCMFx849	Huo Xue Zhuang Jin Pills	活血壮筋丸
TCMF4101	Jian Nao Bu Shen Oral Liquid	健脑补肾口服液
TCMF4108	Jian Nao Bu Shen Pills	健脑补肾丸
TCMF4284	Jin Gu Ning Cha Ji	筋骨宁搽剂
TCMF7155	Jin Gu Tong Xiao Pills	筋骨痛消丸
TCMF4032	Jin Mao Gou Ji Pills	金毛狗脊丸
TCMFx4069	Jin Qian Bai Hua She Yao Wine	金钱白花蛇药酒
TCMF4557	Jiu Zhi Xi Xian Cao Yao Wine	九制豨莶草药酒
TCMFx1962	Jixueteng Concentrated Decoction	鸡血藤膏
TCMF4750	Lu Gu Xue Lian Wine	鹿骨雪莲酒
TCMF1405	Miaoji Pills	妙济丸
TCMF2536	Miaoji Pills	妙济丸
TCMF2197	Mighty Tiger Decoction	威虎汤
TCMF4590	Mu Gua Wine	木瓜酒
TCMFx4470	Pao Tian Hong Wine	炮天红酒
TCMFx2082	Plus and Minus Flower Remover Fries
TCMFx2246	Prescription for Stoppping Leucorrhea	止带方
TCMFx4861	Qi She Feng Shi Wine	蕲蛇风湿酒
TCMFx4874	Qi She Zhui Feng Wine	蕲蛇追风酒
TCMFx5052	Qian Lie Shu Le Granules	前列舒乐颗粒
TCMFx5096	Qiang Jin Ying Xiong Pills	强筋英雄丸
TCMF5177	Qiang Li Tian Ma Du Zhong Capsules	强力天麻杜仲胶囊
TCMF5093	Qu Feng Oral Liquid	驱风液
TCMFx5502	Ren Shen Tian Ma Yao Wine	人参天麻药酒
TCMF2511	Rightness Supporting Antidepressant Decoction	扶正解郁汤
TCMFx5575	Rong Kun Pills	茸坤丸
TCMFx2406	Saint Cover Ruo Opening Decoction
TCMF2833	San Bi Decoction	三痹汤
TCMFx3204	Shen Gui Lu Rong Pills	参桂鹿茸丸
TCMFx5319	Shen Jin Huo Luo Pills	伸筋活络丸
TCMFx556	Shen Jin Huo Luo Pills	伸筋活络丸
TCMFx3517	Shen Rong Bian Pills	参茸鞭丸
TCMFx3541	Shen Rong Duo Bian Wine	参茸多鞭酒
TCMFx3551	Shen Rong Gu Ben Huan Shao Pills	参茸固本还少丸
TCMFx2488	Shi Guo Gong's Prescription for Preparing Medicated Wine
TCMFx5862	Shi Re Bi Granules	湿热痹颗粒
TCMFx1105	Shi Re Bi Tablet	湿热痹片
TCMFx5869	Shi Re Bi Tablets	湿热痹片
TCMF1417	Shujin Huoluo Wine	舒筋活络酒
TCMF2572	Shujin Huoluo Wine	舒筋活络酒
TCMFx2574	Stone Remover Combination Recipe	排石合剂
TCMF5519	Tian Jing Bu Shen Ointment	添精补肾膏
TCMF1090	Tian Jing Bu Shen Ointment	添精补肾膏
TCMF261	Tian Ma Qu Feng Bu Tablet	天麻祛风补片
TCMF5434	Tian Ma Qu Feng Bu Tablets	天麻祛风补片
TCMFx5473	Tian Ma Zhui Feng Ointment	天麻追风膏
TCMFx299	Tian Zhi Granules	天智颗粒
TCMFx982	Tong Bi Capsule	通痹胶囊
TCMF1100	Tong Feng Ding Capsule	痛风定胶囊
TCMFx1819	Tuohua Decoction	脱花煎
TCMF5355	Wan Nian Chun Wine	万年春酒
TCMFx5961	Wen Shen Quan Lu Pills	温肾全鹿丸
TCMFx957	Xiao Yu Kang Capsule	消瘀康胶囊
TCMFx64	Xiao Yu Kang Tablets	消瘀康片
TCMFx1158	Xi Hong Tong Luo Oral Liquid	豨红通络口服液
TCMFx6477	Xue Fu Sheng Tablets	血复生片
TCMFx6061	Yang Xue Yu Feng Wine	养血愈风酒
TCMFx1116	Yao Tong Ning Capsule	腰痛宁胶囊
TCMFx6148	Yao Tong Ning Capsules	腰痛宁胶囊
TCMFx6374	Yi He Chun Capsules	颐和春胶囊
TCMFx6479	Yi Ling Jing	益龄精
TCMF6279	Yu Xue Bi Capsules	瘀血痹胶囊
TCMF6286	Yu Xue Bi Granules	瘀血痹颗粒
TCMF1120	Yu Xue Bi Capsule	瘀血痹胶囊
TCMF1121	Yu Xue Bi Granules	瘀血痹颗粒
TCMFx6310	Zheng Gu Ointment	正骨膏
TCMFx6216	Zhong Feng Hui Chun Pills	中风回春丸
TCMFx326	Zhong Feng Hui Chun Pills	中风回春丸
TCMFx327	Zhong Feng Hui Chun Tablet	中风回春片
TCMF6480	Zhuang Gu Mu Gua Wine	壮骨木瓜酒
TCMFx6570	Zhuang Yao Xiao Tong Oral Liquid	壮腰消痛液
TCMF6588	Zhuang Yuan Hong Yao Wine	状元红药酒
TCMF6641	Zhui Feng Shu Jing Huo Xue Tablets	追风舒经活血片

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT207	BACE1	Beta-secretase 1	Protease	P56817
TCMT232	ABCB1	P-glycoprotein 1	Transporter	P08183

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC966
Formula: C29H44O8

Common Name	Cyasterone
IUPAC Name	(3S,4S,5R)-4-[(2R,3R)-2,3-dihydroxy-3-[(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-6-oxo-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]-3,5-dimethyloxolan-2-one
Canonical SMILES	O[C@H]1C[C@@]2(C)[C@@H](C[C@H]1O)C(=O)C=C1[C@@H]2CC[C@]2([C@@]1(O)CC[C@@H]2[C@]([C@@H](C[C@@H]1[C@@H](C)OC(=O)[C@H]1C)O)(O)C)C
Standard InCHI	InChI=1S/C29H44O8/c1-14-16(15(2)37-25(14)34)10-24(33)28(5,35)23-7-9-29(36)18-11-20(30)19-12-21(31)22(32)13-26(19,3)17(18)6-8-27(23,29)4/h11,14-17,19,21-24,31-33,35-36H,6-10,12-13H2,1-5H3/t14-,15+,16-,17-,19-,21+,22-,23-,24+,26+,27+,28+,29+/m0/s1
Standard InCHIKey	NEFYSBQJYCICOG-YSEUJXISSA-N
External Identifiers	ChEMBL [CHEMBL494249]; PubChem [119444];
Reference of Component-Ingredient Pair	19021756

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH289	Cyathula officinalis	Chuan Niu Xi	川牛膝

Ingredient ID: TCMC2050
Formula: C11H10O4

Common Name	Scoparone
IUPAC Name	6,7-dimethoxychromen-2-one
Canonical SMILES	COc1cc2oc(=O)ccc2cc1OC
Standard InCHI	InChI=1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3
Standard InCHIKey	GUAFOGOEJLSQBT-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL325864]; PubChem [8417];
Reference of Component-Ingredient Pair	23017425

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2083	Viola philippica	Tian Di Ding	甜地丁
TCMH2495	Artemisia capillaris	Yin Chen Hao Gan Jin Gao	茵陈蒿干浸膏
TCMH1657	Radix moghaniae philippinensis	Qian Jin Ba	千斤拔
TCMH2145	Achyranthes aspera	Tu Niu Xi	土牛膝
TCMH568	Euphorbia hirta	Fei Yang Cao	飞杨草
TCMH679	Pueraria lobata	Ge Hua	葛花
TCMH1460	Zanthoxylum nitidum	Mao Liang Mian Zhen	毛两面针
TCMH2642	Gardenia jasminoides	Zhi Zi Jin Gao	栀子浸膏
TCMH2456	Eupatorium lindleyanum	Ye Ma Zhui	野马追
TCMH1162	Sarcandra glabra	Jiu Jie Cha	九节茶
TCMH619	Citrus medica var. sarcodactylis	Fo Shou	佛手
TCMH1933	Herba dendrobii	Shi Hu	石斛
TCMH2450	Scoparia dulcis	Ye Gan Cao	野甘草
TCMH961	Artemisia scoparia	Huang Hao	黄蒿
TCMH2511	Zanthoxylum avicennae	Ying Bu Bo	鹰不泊
TCMH348	Lobelia chinensis	Da Ban Bian Lian	大半边莲
TCMH1272	Forsythia suspensa	Lian Qiao	连翘
TCMH289	Cyathula officinalis	Chuan Niu Xi	川牛膝
TCMH2282	Citrus medica	Xiang Yuan Pi	香橼皮
TCMH1686	Canarium album	Qing Guo Tan	青果炭
TCMH13	Artemisia argyi	Ai Ye You	艾叶油
TCMH2035	Pinus massoniana	Song Zhi	松脂
TCMH2211	Artemisia princeps	Wu Yue Ai	五月艾
TCMH1846	Artemisia capillaris	Shan Yin Chen	山茵陈
TCMH2154	Artemisia capillaris	Tu Yin Chen Hao	土茵陈蒿
TCMH2494	Artemisia capillaris	Yin Chen Hao	茵陈蒿
TCMH1417	Pinus massoniana	Ma Wei Song Gen	马尾松根
TCMH1418	Pinus massoniana	Ma Wei Song Shu Gen	马尾松树根
TCMH2033	Pinus massoniana	Song Xiang	松香
TCMH122	Lobelia chinensis	Ban Bian Lian	半边莲
TCMH2281	Citrus medica	Xiang Yuan	香橼
TCMH431	Achyranthes aspera	Dao Kou Cao	倒扣草
TCMH12	Artemisia argyi	Ai Ye	艾叶
TCMH221	Sarcandra glabra	Cao Shan Hu Jin Gao	草珊瑚浸膏
TCMH644	Pueraria lobata	Gan Ge	干葛
TCMH677	Pueraria lobata	Ge Gen	葛根
TCMH678	Pueraria lobata	Ge Gen Gan Jin Gao	葛根干浸膏
TCMH650	Canarium album	Gan Lan	橄榄
TCMH1683	Canarium album	Qing Guo	青果
TCMH1856	Gardenia jasminoides	Shan Zhi	山栀
TCMH2641	Gardenia jasminoides	Zhi Zi	栀子

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC966	C29H44O8	Cyasterone	520.3	-1.1455	3.77	1.159	8	5	144.52	14	5	37	0
TCMC2050	C11H10O4	Scoparone	206.06	0.1664	2.23	1.607	1	0	44.76	4	2	15	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Cyathula officinalis 川牛膝

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC966

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2050

Occurrence of the ingredient across TCM components

Properties

Download Data