| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CDK6, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, DRD3, EGFR, ESR1, F10, F2, F3, FABP3, FABP4, FLT3, GPER1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MAOA, MET, MIF, MTNR1B, POLA1, POLB, PPARA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
14.8503 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.1924 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.1924 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA3, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ESR1, ESRRA, FABP3, GPER1, HSD11B2, HSD17B2, IGF1R, INSR, MMP2, MMP9, NR3C1, POLB, PPARA, PTGES, RORC, SRC, TEK, TRPV1, TYR |
13.7019 |
|
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, HSD11B2, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, POLB, PPARA, PTGES, RORC, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
13.2097 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, NR3C1, POLB, PPARA, PTGES, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
13.0468 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, ALOX12, APP, AR, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESRRA, F2, F3, FABP3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NUAK1, PGR, PIM1, PTGES, SMAD3, SRC, TEK, TERT, XDH |
12.9449 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MIF, MMP12, MMP9, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.4799 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FLT3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, NR3C1, PGR, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
12.4214 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
12.2429 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
11.7358 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.5075 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CYP1B1, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MIF, PTPN1, SRC, TEK, XDH |
11.4546 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CACNA1C, CDK6, CNR1, DRD3, EGFR, F2, GPER1, HCAR2, HTR2A, HTR2B, HTR2C, KDR, MIF, SRC, TNKS, TNKS2, TRPV1 |
11.121 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ESR1, ESRRA, FLT3, GPER1, HSD11B2, NR3C1, PTGES, RORC, SRC, TEK, TRPV1, TYR |
11.0729 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, F3, FLT3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1B, NUAK1, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.0729 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRB1, AKR1B1, ALOX12, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD3, EGFR, ESR1, F2, FABP3, FABP4, FLT3, GPER1, GPR35, HTR2A, HTR2B, HTR2C, INSR, MET, MTNR1B, POLA1, POLB, SMAD3, SRC, TERT, TRPV1 |
10.9475 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, F3, FLT3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1B, NUAK1, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.8963 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, APP, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, ESR1, FABP3, FABP4, FUT7, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, MIF, PPARA, PTGES, TBXAS1, TRPV1 |
10.8207 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESRRA, F10, F2, F3, FABP4, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.7058 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CACNA1C, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, F2, F3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1B, PPARA, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
10.6024 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, NR3C1, PGR, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.5494 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, FUT7, GBA2, GLO1, HSPA1A, HTR2B, HTR2C, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR, XDH |
10.389 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP9, NUAK1, PTPN1, SRC, TEK, XDH |
10.364 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD11B2, HSD17B2, NR3C1, PTGES, RORC, SRC, TYR |
10.3639 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, ALOX12, AR, BCL2, CDC25B, CDK6, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, PIM1, TEK, TERT |
10.1112 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, HCAR2, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
9.70334 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, HCAR2, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
9.52716 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA3, CA6, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESRRA, F10, F2, F3, FABP3, FABP4, FLT3, GPER1, HSD11B2, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, NR3C1, NUAK1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
9.28915 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, HCAR2, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
9.12265 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
9.12265 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ERBB2, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD11B2, IGF1R, INSR, MMP2, NR3C1, PPARA, SMAD3, SRC, TEK, TRPV1 |
9.10535 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.03808 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGES, TBXAS1 |
8.68637 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
8.62221 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD11B2, INSR, NR3C1, PPARA, SRC, TEK, TRPV1 |
8.58171 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, CACNA1C, DRD3, F2, GPER1, HTR2A, HTR2B, HTR2C, KDR, SRC, TRPV1 |
8.56235 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.55136 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, BCL2, CA3, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DRD3, EGFR, FABP3, HSD11B2, HTR2A, HTR2B, HTR2C, KDR, NR3C1, POLB, SRC, TRPV1 |
8.53521 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.5269 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD3, EGFR, ERBB2, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
8.50392 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CACNA1C, CDK6, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
8.47959 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGES, TBXAS1 |
8.43309 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, ERBB2, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
8.42729 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRB1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CACNA1C, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ESR1, ESRRB, F10, F2, F3, FABP4, GPER1, HSD11B2, HSD17B2, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
8.41691 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX12, ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES, TBXAS1 |
8.37833 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, ESRRB, F2, FABP3, FLT3, GPER1, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, MMP9, MTNR1A, PTPN1, SMAD3, SRC, TEK, XDH |
8.10601 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, ESRRB, F2, FABP3, FLT3, GPER1, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, MMP9, MTNR1A, PTPN1, SMAD3, SRC, TEK, XDH |
8.10601 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.07303 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, ALOX12, APP, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD3, EGFR, ESR1, F2, FABP3, FABP4, GPER1, GPR35, HTR2A, HTR2B, HTR2C, INSR, MET, MTNR1B, SMAD3, TRPV1 |
8.02237 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.02213 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CACNA1C, CNR1, CYP19A1, CYP1A1, CYP1B1, EGFR, ESR1, GPER1, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR2A, HTR2C, MTNR1B |
8.01478 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRB1, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CACNA1C, CDK6, CNR1, CNR2, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, MTNR1A, MTNR1B, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
7.95708 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRB1, AKR1B1, ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, F10, F2, F3, FABP4, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.94685 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MTNR1A, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
7.87014 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.75125 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, ESR1, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
7.71627 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD3, DUSP3, EGFR, ERBB2, ESRRB, F2, FABP3, FABP4, FLT3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP9, MTNR1A, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
7.67819 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRB1, ALOX15, APP, AR, BCL2, CDC25B, DRD3, DUSP3, EGFR, ERBB2, ESRRB, F2, FABP3, FABP4, FLT3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP9, MTNR1A, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
7.59164 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
7.52386 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, DRD3, F2, FABP3, FLT3, GPER1, HCAR2, HTR2A, HTR2B, HTR2C, PPARA, RORC, SRC, TEK |
7.50901 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
7.43565 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRB1, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CACNA1C, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD17B2, HTR2A, HTR2B, INSR, KDR, MET, MIF, MMP2, MMP9, PGR, PIM1, POLB, PPARA, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
7.42102 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, GPER1, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, RORC, SMAD3, SRC, TERT, TRPV1 |
7.36676 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX12, ALOX15, AR, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, F2, GPER1, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
7.36464 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
7.31763 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRB1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, F3, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NUAK1, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.28605 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK, TERT |
7.28546 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TERT |
7.28546 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DUSP3, EGFR, ERBB2, GPER1, HTR2A, HTR2B, HTR2C, KDR, MIF, PTPN1, SRC, TEK |
7.18663 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, EGFR, ERBB2, FLT3, GPER1, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, PTPN1, SRC, TEK, XDH |
7.18315 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRB1, ALOX12, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CNR1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, F3, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MET, MIF, MMP12, MMP9, PIM1, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
7.18315 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRB1, ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD3, EGFR, ESRRB, F2, F3, GPER1, HCAR2, HSPA1A, HTR2A, HTR2B, KDR, MET, MIF, MMP12, MMP9, PIM1, SMAD3, SRC, TEK, TERT, TRPV1 |
7.06956 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CYP19A1, DRD3, EGFR, ERBB2, F2, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, MIF, MMP12, MMP9, MTNR1B, PPARA, PTPN1, SMAD3, SRC, TERT, TRPV1 |
7.0031 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, MMP9, PTGES, SRC, TERT |
6.97164 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.8675 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADRB1, APP, AR, AURKB, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, MTNR1A, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
6.84209 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ERBB2, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, POLB, PPARA, SMAD3, SRC, TEK, TYR |
6.82583 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, MIF, PTGES, TBXAS1 |
6.76641 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK, TERT |
6.69076 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, GPER1, IGF1R, INSR, KDR, MMP2, NR3C1, RORC, SMAD3, SRC, TRPV1 |
6.60857 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, ESR1, FABP4, FLT3, GPER1, HSPA1A, IGF1R, INSR, KDR, MIF, MMP2, MMP9, NR3C1, NUAK1, POLA1, POLB, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
6.56637 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DUSP3, EGFR, ERBB2, FLT3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, PTPN1, SRC, TEK, XDH |
6.48658 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD3, EGFR, ERBB2, F10, F3, GPER1, INSR, MET, SRC, TEK, XDH |
6.47155 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD3, DUSP3, EGFR, ERBB2, ESR1, F2, F3, FABP4, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MIF, MMP9, NUAK1, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.4669 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
6.38656 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MAOA, NQO2, TBXAS1, TYR, XDH |
6.35473 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, ESRRB, F2, FLT3, GPER1, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, MMP9, PTPN1, SRC, TEK, XDH |
6.29371 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, ALOX12, APP, CDK6, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, F2, F3, FABP4, GPER1, HSPA1A, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
6.2894 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC, TEK |
6.23293 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
6.19286 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, ADRB1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD3, EGFR, HSD11B2, HSPA1A, HTR2A, HTR2B, MMP2, POLB, PPARA, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
6.19286 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX12, ALOX15, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGES, TBXAS1 |
6.17405 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD3, EGFR, ESR1, MTNR1A, MTNR1B, PGR, PPARA, RORC, SRC, TOP2A |
6.0703 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.0687 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
6.04122 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.03078 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADRB1, APP, AR, AURKB, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, MTNR1A, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
6.00921 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, HTR2A, HTR2B, HTR2C, MIF, SRC, TNKS, TNKS2, TRPV1 |
5.98013 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, F2, FLT3, GPER1, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, MMP9, PTPN1, SRC, TEK, XDH |
5.96592 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, GPER1, NR3C1, RORC, SRC, TRPV1 |
5.93902 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, MIF, PPARA, PTGES, TBXAS1 |
5.88437 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD3, FABP3, PPARA, TRPV1 |
5.88437 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
5.85064 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX12, ALOX15, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, FABP3, FABP4, FUT7, GBA2, MET, MIF, PPARA, PTGES, TBXAS1 |
5.83452 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.80575 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, EGFR, GPER1, HTR2A, HTR2B, HTR2C, KDR, MIF, SRC, TEK |
5.78597 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRB1, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, F2, F3, FABP4, FLT3, GPER1, GPR35, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MET, MIF, MMP9, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
5.67686 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CACNA1C, CNR1, DRD3, EGFR, ERBB2, F2, GPER1, HCAR2, HTR2B, HTR2C, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC |
5.67686 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
5.57565 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, GPER1, GPR35, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PTPN1, SMAD3, SRC, TERT, XDH |
5.57139 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, GPER1, GPR35, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PTPN1, SMAD3, SRC, TERT, XDH |
5.54782 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD3, EGFR, ESR1, F2, FABP3, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
5.50757 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ERBB2, ESRRB, F2, FABP4, FLT3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP9, PPARA, PTPN1, SRC, TEK, XDH |
5.46664 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
F2, FABP3, FLT3, HTR2A, HTR2B, HTR2C, PPARA, SRC, TEK |
5.45503 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.45135 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD3, EGFR, FABP3, FLT3, GPER1, HSD11B2, IGF1R, INSR, MMP2, PPARA, SRC, TEK, TRPV1, TYR |
5.41691 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, GPER1, HCAR2, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
5.39597 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, NUAK1, PIM1, POLB, PTPN1, SRC, TEK, TNKS, XDH |
5.37521 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRB1, APP, AR, AURKB, BCL2, CDC25B, EGFR, ERBB2, ESR1, ESR2, F2, F3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, INSR, MET, MIF, MMP9, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.33864 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ADRB1, ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, F3, GPER1, HTR2A, HTR2C, INSR, KDR, MIF, NUAK1, PIM1, PPARA, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
5.32087 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CNR1, CNR2, CYP1A1, CYP1B1, DRD3, KDR, POLB, SRC |
5.26652 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ALOX12, CNR1, CNR2, CYP19A1, DRD3, EGFR, ESR1, F2, F3, FABP4, GPER1, KDR, MET, MIF, MMP12, PPARA, SMAD3, TEK |
5.23269 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD3, EGFR, F2, GPER1, HCAR2, TNKS, TNKS2 |
5.22467 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD3, EGFR, ERBB2, F2, GPER1, HCAR2, HTR2B, INSR, MIF, MMP12, SMAD3, SRC, TERT, TRPV1 |
5.19622 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRB1, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.19597 |
|
[BP] GO:0032787 |
None
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, MIF, PPARA, PTGES, TBXAS1 |
5.17807 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, EGFR, ERBB2, F2, PPARA, SMAD3 |
5.17067 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD3, EGFR, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
5.08883 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, EGFR, ERBB2, F2, GPER1, HSD11B2, HSPA1A, HTR2C, MIF, MMP2, MMP9, NUAK1, POLA1, POLB, PPARA, PTGES, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
5.08883 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD3, EGFR, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
5.06154 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.05696 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, GPER1, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP9, PTPN1, SRC, TEK, XDH |
5.04011 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.04011 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.98035 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.98035 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, FLT3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, NUAK1, PIM1, POLB, PTPN1, SRC, TEK, TNKS, XDH |
4.98035 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD3, EGFR, FABP3, FLT3, GPER1, HSD11B2, IGF1R, INSR, MMP2, PPARA, SRC, TEK, TRPV1, TYR |
4.96394 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TERT, TNKS, TOP2A |
4.91958 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.89992 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, MMP9, PTPN1, SMAD3, SRC, TEK, XDH |
4.89992 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD3, DUSP3, EGFR, GPER1, INSR, MIF, SRC, TERT |
4.86329 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ERBB2, ESR1, ESRRA, ESRRB, F2, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, MMP9, PGR, PIM1, POLB, PPARA, RORC, SMAD3, SRC, TEK, TYR |
4.83804 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, HCAR2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.83145 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CDK6, CYP1B1, EGFR, ESR1, GPER1, IGF1R, INSR, MMP2, MMP9, NR3C1, RORC, SRC, TRPV1 |
4.8305 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRB1, APP, AURKB, BCL2, CDC25B, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, INSR, MIF, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
4.8239 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC, TEK |
4.82075 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, ESR1, F2, F3, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, MMP9, PTPN1, SMAD3, SRC, TEK, XDH |
4.80615 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CACNA1C, CNR1, CSNK2A1, DRD3, EGFR, ERBB2, F2, GPER1, HCAR2, HTR2B, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC, TERT |
4.7981 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
4.79097 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, ERBB2, F10, F3, INSR, MET, SRC, TEK |
4.77526 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
4.75628 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CACNA1C, CNR1, DRD3, EGFR, GPER1, HCAR2, HTR2B, HTR2C, MIF, MMP12, MTNR1B, SRC |
4.73693 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, GPER1, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
4.70779 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.7004 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, F2, GPER1, PPARA, SMAD3, TEK |
4.61712 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
4.61314 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, GPER1, NR3C1, PGR, SRC |
4.60637 |
|
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, ERBB2, F3, HTR2B, KDR, MMP12, PGR, SMAD3, TEK, XDH |
4.57436 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
4.55707 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD3, FABP3, PPARA, TRPV1 |
4.55226 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DRD3, ESR1, GPER1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.51594 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, EGFR, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
4.51177 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.50572 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, GPER1, HSD11B2, NR3C1, SRC |
4.45668 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, HTR2A, HTR2B, IGF1R, INSR, MIF, PTPN1, SRC |
4.45096 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, ALOX12, CNR2, CYP19A1, DRD3, F2, GPER1, MIF, PPARA, SMAD3, TEK |
4.42366 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD3, GBA2, MAOA, TYR |
4.38206 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, F2, GPER1, MMP12, PPARA, SMAD3, TEK |
4.38206 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
4.35558 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRB1, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, MTNR1A, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.35558 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GPER1, HSD11B2, IGF1R, INSR, PPARA, SRC, TEK, TRPV1 |
4.3449 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CACNA1C, CNR1, CYP19A1, DRD3, EGFR, GPER1, HCAR2, HTR2A, HTR2B, HTR2C, MIF, MMP12, MTNR1B, SRC, TRPV1 |
4.34364 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CACNA1C, CNR1, DRD3, EGFR, ERBB2, F2, GPER1, HCAR2, HTR2B, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC |
4.32689 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, EGFR, ERBB2, F2, FLT3, GPER1, HTR2A, HTR2B, HTR2C, INSR, KDR, MIF, MMP9, PTPN1, SRC, TEK, XDH |
4.31826 |
|
[BP] GO:0040008 |
regulation of growth
|
ADRB1, ALOX12, APP, AR, BCL2, CSNK2A1, DRD3, EGFR, ERBB2, ESR2, F2, HSPA1A, INSR, PIM1, SMAD3, TNKS2 |
4.31743 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ERBB2, ESR1, FLT3, MET, MIF, PIM1, POLA1, SRC, TEK, TYR |
4.31064 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, POLB, PPARA, SMAD3, SRC, TEK, TERT |
4.27123 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
4.24386 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PTPN1, SRC, TEK, XDH |
4.21972 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.21075 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRB1, CNR1, CNR2, DRD3, GPER1, HTR6, MTNR1A, MTNR1B |
4.16467 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, CNR1, CNR2, DRD3, EGFR, GPER1, HTR2A |
4.13837 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, CNR1, CNR2, DRD3, EGFR, GPER1, HTR2A |
4.13837 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2 |
4.12625 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CACNA1C, CNR1, CYP19A1, DRD3, EGFR, GPER1, HCAR2, HTR2A, HTR2B, HTR2C, MIF, MMP12, MTNR1B, SRC |
4.09401 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, EGFR, ERBB2, ESR1, FLT3, GPER1, IGF1R, INSR, MMP2, NR3C1, SMAD3, SRC, TRPV1 |
4.08757 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.03552 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CACNA1C, CNR1, DRD3, EGFR, ERBB2, F2, GPER1, HCAR2, HTR2B, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC |
3.99757 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD3, DUSP3, EGFR, GPER1, HSPA1A, INSR, MIF, PIM1, SMAD3, SRC, TERT, TNKS, TOP2A |
3.99456 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD3, EGFR, GPER1, HCAR2, HTR2B, MIF, MMP12, SRC, TRPV1 |
3.98015 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, POLA1, SMAD3, TRPV1 |
3.97475 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, FABP4, GPER1, HSPA1A, MMP12, MMP2, PPARA, PTPN1, SMAD3, SRC, TEK |
3.96906 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DRD3, GPER1, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.96319 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, TERT |
3.96319 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGES, TERT |
3.92152 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, FABP4, GPER1, PPARA, SMAD3, TEK |
3.92043 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.8897 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, SMAD3, SRC, TEK, TERT |
3.87361 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, EGFR, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
3.87361 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRB1, AR, CNR1, DRD3, HSD11B2, PPARA, SMAD3 |
3.86395 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.86395 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP4, FLT3, GLO1, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.86395 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX12, ALOX15, ALOX5, MIF, PTGES |
3.84426 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD3, EGFR, GPER1, HSPA1A, INSR, MIF, TERT, TNKS |
3.83674 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CACNA1C, CNR1, CYP19A1, EGFR, GPER1, HCAR2, HTR2A, HTR2C, MTNR1B |
3.8285 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PTPN1, SRC |
3.81541 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DUSP3, ERBB2, ESR1, ESRRA, F2, GPER1, HCAR2, HSPA1A, MIF, MMP12, MMP2, PTPN1, SMAD3, SRC |
3.80744 |
|
[BP] GO:0045913 |
None
|
ESRRB, GPER1, HTR2A, INSR, PPARA, SRC |
3.79724 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, SMAD3, SRC, TEK, TERT |
3.77648 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.76293 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.76293 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, GPER1, HSD11B2, NR3C1, SRC |
3.76098 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRB1, EGFR, GPER1, HTR2A, HTR2B, SRC, TEK |
3.76098 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DUSP3, ERBB2, GPER1, MIF, MMP12 |
3.75227 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, MIF, PTPN1, SRC, TEK, TNKS |
3.74591 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
3.72223 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.70528 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, CACNA1C, DRD3, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
3.69164 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CA3, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.66485 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, DRD3, DUSP3, ESR1, ESR2, ESRRA, F2, FABP4, GPER1, HSPA1A, HTR2B, IGF1R, MET, MIF, MMP12, MMP9, NR3C1, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.66485 |
|
[BP] GO:0051282 |
None
|
CACNA1C, F2, GPER1, HTR2A, HTR2B, HTR2C, TRPV1 |
3.65091 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.62693 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, GPER1, NR3C1, SRC |
3.60829 |
|
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX12, ALOX15, ALOX5 |
3.60737 |
|
[BP] GO:0045776 |
None
|
ADORA1, ADRB1, CNR1, DRD3, PPARA |
3.60461 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SRC, TEK |
3.60461 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, MMP2, MMP9, MTNR1A, PGR, SRC, TOP2A |
3.59873 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, KDR, NR3C1, SRC, TRPV1 |
3.59873 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, ERBB2, F2, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, MIF, PTPN1, SRC, TEK |
3.59391 |
|
[BP] GO:0050708 |
None
|
ACHE, CACNA1C, CNR1, DRD3, EGFR, GPER1, HCAR2, HTR2B, MIF, MMP12, MTNR1B, SRC |
3.58563 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
CACNA1C, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, SMAD3, TRPV1 |
3.56257 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
3.55797 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, ADRB1, AKR1B1, ALOX12, HTR2A, MET, TRPV1 |
3.54432 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR |
3.53387 |
|
[BP] GO:0051254 |
None
|
APP, AR, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSPA1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
3.53175 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, F2, INSR, SMAD3, TRPV1, XDH |
3.51957 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
3.51957 |
|
[BP] GO:0050866 |
negative regulation of cell activation
|
ALOX12, AXL, CNR1, CNR2, DUSP3, ERBB2, F2, GPER1 |
3.50338 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, FUT7, GBA2, GLO1, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLB, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.50054 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, DRD3, DUSP3, ESR1, FABP4, GPR35, IGF1R, MET, MMP9, PIM1, PPARA, PTPN1, SRC, TNKS |
3.49146 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, EGFR, ERBB2, F2, GPER1, HCAR2, HTR2B, MIF, MMP12, SMAD3, SRC |
3.47858 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, EGFR, ERBB2, F2, FLT3, HTR2A, HTR2B, INSR, MIF, PTPN1, SRC, TEK, TNKS |
3.47817 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD3, DUSP3, ESR1, GPER1, HSPA1A, IGF1R, MET, MIF, MMP9, PTPN1, SRC, XDH |
3.46482 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CNR1, CYP1A1, HTR2A, MIF, POLB, TERT |
3.45189 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRB1, CACNA1C, DRD3, EGFR, GPER1, GPR35, HCAR2, HTR2A, HTR2C, SMAD3, TRPV1 |
3.44962 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.4421 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, ERBB2, F10, F2, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP2A |
3.42888 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, ERBB2, F3, HTR2B, KDR, MMP12, TEK |
3.42665 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRB1, APP, CA2, CNR1, CNR2, DRD3, ESR1, F2, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, INSR, MTNR1A, MTNR1B, SRC |
3.4225 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
AR, BCL2, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, GPER1, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTPN1, SMAD3, SRC, TERT, XDH |
3.41316 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.41316 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.41316 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.41316 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, APP, BCL2, CA2, CA7, CACNA1C, CNR1, DRD3, F2, GPER1, GPR35, HTR2A, MIF, MMP9 |
3.41316 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, ESR2, F2, GPER1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.41316 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.40609 |
|
[BP] GO:0045893 |
None
|
APP, AR, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
3.37249 |
|
[BP] GO:1903508 |
None
|
APP, AR, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
3.37249 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, BCL2, CDK6, CYP1B1, ERBB2, FABP3, GPER1, HSPA1A, PTGES, SMAD3, TERT, XDH |
3.37149 |
|
[BP] GO:1902680 |
None
|
APP, AR, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
3.37037 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.34593 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
3.27791 |
|
[BP] GO:0051093 |
None
|
ADRB1, APP, BCL2, CDK6, DRD3, EGFR, ERBB2, ESRRB, F2, GPER1, MIF, PPARA, SMAD3, TEK, TERT, TRPV1, XDH |
3.27791 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.26347 |
|
[BP] GO:0007210 |
None
|
HTR2A, HTR2B, HTR2C, HTR6 |
3.26347 |
|
[BP] GO:0098664 |
None
|
HTR2A, HTR2B, HTR2C, HTR6 |
3.26347 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MTNR1A, NR3C1, NR3C2, PGR, PIM1, POLA1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.26347 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
CACNA1C, ESR1, F2, GPER1, GPR35, HTR2A, HTR2B, HTR2C, TRPV1 |
3.24635 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, EGFR, ERBB2, F2, FLT3, HTR2A, HTR2B, INSR, MIF, PTPN1, SRC, TEK |
3.2405 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PPARA, PTPN1, SMAD3 |
3.23667 |
|
[BP] GO:0010676 |
None
|
ESRRB, GPER1, INSR, PPARA, SRC |
3.2166 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX12, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PTGES |
3.20237 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, F2, INSR, SMAD3, TRPV1, XDH |
3.19786 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADRB1, ALPL, APP, AR, AXL, BCL2, CDC25B, CDK6, CYP1A1, EGFR, ERBB2, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HTR2B, KDR, MET, MIF, MMP2, MMP9, PGR, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
3.19653 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD3, EGFR, GPER1, INSR, MAOA, SMAD3, TRPV1 |
3.1613 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, EGFR, GPER1, HCAR2, HTR2B, MIF, MMP12, SRC |
3.1613 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.14938 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CACNA1C, CNR1, CNR2, GPER1, GPR35, KDR, SRC, TRPV1 |
3.12977 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, GPER1, HSPA1A, IGF1R, KDR, MIF, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.11849 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, EGFR, ERBB2, F2, GPER1, HCAR2, HTR2B, MIF, MMP12, SMAD3, SRC |
3.11488 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD3, GPR35, HTR2A, MMP9 |
3.11442 |
|
[BP] GO:0032768 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
3.10992 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTPN1, SRC |
3.07621 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MET, PPARA, SMAD3 |
3.06581 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, ESRRB, F3, GPER1, HTR2A, HTR2C, INSR, KDR, PIM1, SMAD3, SRC, TEK, TERT |
3.06029 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR |
3.0532 |
|
[BP] GO:0045596 |
None
|
APP, BCL2, CDK6, DRD3, EGFR, ERBB2, ESRRB, F2, GPER1, PPARA, SMAD3, TERT, TRPV1, XDH |
3.03707 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, F2, FLT3, GPER1, KDR, TEK |
3.03239 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRB1, EGFR, GPER1, HTR2A, HTR2B, SRC, TEK |
2.99471 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SRC, TERT |
2.99471 |
|
[BP] GO:1901184 |
None
|
ADORA1, APP, EGFR, ERBB2, GPER1, MMP9 |
2.98535 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.97441 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK |
2.97236 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, GLO1, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR |
2.96713 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX12, ALOX15, MIF, PTGES |
2.96713 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SMAD3, SRC, TERT, TNKS |
2.96642 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.95664 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.95664 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRB1, AR, AXL, BCL2, CACNA1C, CNR1, DRD3, ESR2, HTR2A, HTR2C, HTR6, MTNR1B, PGR, TEK, TRPV1 |
2.95391 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, ERBB2, FLT3, HTR2A, HTR2B, IGF1R, INSR, MIF, PTPN1, SRC |
2.95391 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.95391 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.95391 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.95391 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.95391 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
ALOX12, BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.93067 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PTPN1, SRC, TERT |
2.92622 |
|
[BP] GO:0035265 |
organ growth
|
AR, BCL2, CYP19A1, ESR1 |
2.9212 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
2.91114 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRB1, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, DRD3, EGFR, ERBB2, GPER1, HTR2A, HTR2B, IGF1R, INSR, KDR, MET, MIF, NUAK1, POLB, PTPN1, SRC, TEK |
2.91114 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, GPER1, HSD11B2, INSR, PPARA, SRC, TEK, TRPV1 |
2.91027 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F2, F3, FABP4, KDR, MET, MIF, SMAD3 |
2.90077 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, EGFR, ERBB2, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.90077 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PTPN1, SRC |
2.90077 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PGR, SRC |
2.88656 |
|
[BP] GO:0001659 |
None
|
ADORA1, ADRB1, HTR2A, TRPV1 |
2.87466 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
ERBB2, HTR2A, HTR2B, IGF1R |
2.87466 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.87066 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESRRA, F2, F3, GPER1, INSR, KDR, PIM1, SMAD3, SRC, TEK, TERT, XDH |
2.86442 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, ERBB2, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, MIF, PTPN1, SRC |
2.86227 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, GPER1, HSPA1A, IGF1R, MIF, MMP12, MMP9, NR3C1, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.85996 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, CDK6, EGFR, ESR1, FLT3, GPER1, NR3C1, RORC, SRC |
2.85863 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
ADRB1, MMP1, MMP12, MMP2, MMP9, TRPV1 |
2.85736 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, ADRB1, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, MTNR1A, NR3C1, NR3C2, PGR, PIM1, POLA1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.85736 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, F2, GPER1, MIF, POLB, PTGES, TRPV1 |
2.85491 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.85491 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD3, HTR2A, HTR2B |
2.84904 |
|
[BP] GO:0060402 |
None
|
CACNA1C, HTR2A, HTR2B, HTR2C, TRPV1 |
2.84904 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
2.82148 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F2, F3, FABP4, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PTPN1, SMAD3, SRC, TEK, XDH |
2.80416 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.80416 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.80416 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.80416 |
|
[BP] GO:2001301 |
lipoxin biosynthetic process
|
ALOX12, ALOX15 |
2.80416 |
|
[BP] GO:2001302 |
lipoxin A4 metabolic process
|
ALOX12, ALOX15 |
2.80416 |
|
[BP] GO:2001303 |
lipoxin A4 biosynthetic process
|
ALOX12, ALOX15 |
2.80416 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, EGFR, ERBB2, F2, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, MIF, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
2.80158 |
|
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
F2, FLT3, GPER1, KDR, TEK |
2.80158 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, DRD3, EGFR, HSPA1A, MAOA |
2.80158 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.80158 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.80158 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B |
2.80158 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
ADRB1, APP, BCL2, DRD3, TNKS2 |
2.77571 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.75979 |
|
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CDK6, CNR1, DRD3, EGFR, ERBB2, ESRRA, ESRRB, F2, GPER1, HTR2A, HTR2C, KDR, PPARA, RORC, SMAD3, TERT, TRPV1, XDH |
2.73119 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, NQO2, RORC |
2.71604 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD3, EGFR, HTR2A, HTR2B, HTR2C, INSR, MTNR1A, PPARA, TRPV1 |
2.71604 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, HTR2A, MIF, PTPN1, SRC |
2.70484 |
|
[BP] GO:1900544 |
None
|
ADRB1, ESRRB, GPER1, HTR2A, INSR, MTNR1A |
2.6982 |
|
[BP] GO:0045981 |
None
|
ADRB1, ESRRB, GPER1, HTR2A, INSR, MTNR1A |
2.6982 |
|
[BP] GO:1900542 |
None
|
ADRB1, DRD3, ESRRB, GPER1, HTR2A, INSR, MTNR1A, PPARA |
2.66822 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B |
2.6623 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.65893 |
|
[BP] GO:0050714 |
None
|
ACHE, EGFR, GPER1, HCAR2, HTR2B, MIF, MMP12, SRC |
2.65817 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, GPER1, HSPA1A, MIF, MMP9, PTPN1, SMAD3, SRC, TERT |
2.65721 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, EGFR, F2, FUT7, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, SRC, TEK |
2.63179 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GPER1, HTR2A, INSR, PPARA, RORC, SRC |
2.63054 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
ALOX12, CYP1B1, F3, GPER1, KDR, TEK, TERT |
2.61675 |
|
[BP] GO:0050865 |
regulation of cell activation
|
ALOX12, APP, AXL, BCL2, CNR1, CNR2, DUSP3, ERBB2, F2, GPER1, MIF, SRC |
2.60228 |
|
[BP] GO:0006140 |
None
|
ADRB1, DRD3, ESRRB, GPER1, HTR2A, INSR, MTNR1A, PPARA |
2.59094 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, EGFR, GPER1 |
2.59031 |
|
[BP] GO:0010675 |
None
|
ESRRB, GPER1, INSR, PPARA, RORC, SRC |
2.59031 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, TYR |
2.58223 |
|
[BP] GO:0006357 |
None
|
APP, AR, AURKB, CA9, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GLO1, GPER1, HSPA1A, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, TERT, TNKS, TOP2A, TRPV1 |
2.58087 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, SRC |
2.58087 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.57486 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GPER1, IGF1R, INSR, MMP2, SRC, TRPV1 |
2.54605 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
GPER1, MMP2, MMP9, TERT |
2.54605 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, MMP2, MMP9, TERT |
2.54605 |
|
[BP] GO:0060401 |
None
|
CACNA1C, HTR2A, HTR2B, HTR2C, TRPV1 |
2.54605 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRB1, EGFR, GPER1, HTR2A, HTR2B |
2.54257 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRB1, EGFR, GPER1, HTR2A, HTR2B |
2.54257 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, F2, HSD11B2, HTR2A, MMP12, PTGES, SMAD3, SRC, TRPV1, TYR |
2.53949 |
|
[BP] GO:0042060 |
None
|
ALOX15, EGFR, ERBB2, PPARA, SMAD3 |
2.52357 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.50765 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD3, MAOA, TYR |
2.49857 |
|
[BP] GO:0050965 |
None
|
ADORA1, HTR2A, TRPV1 |
2.49313 |
|
[BP] GO:0050961 |
None
|
ADORA1, HTR2A, TRPV1 |
2.49313 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.49313 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX12, ALOX15, BCL2, CDK6, CYP1B1, DUSP3, ERBB2, KDR, NUAK1, PPARA, SMAD3, SRC, TEK |
2.4817 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, GPER1, MMP2, MMP9, TERT |
2.47621 |
|
[BP] GO:0006811 |
None
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD3, FABP3, HTR2A, HTR2B, HTR2C, PPARA, TRPV1 |
2.47603 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.47603 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.47603 |
|
[BP] GO:1901570 |
None
|
ALOX12, ALOX15, ALOX5, MIF, PTGES |
2.45761 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, ADRB1, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GPER1, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, MTNR1A, NR3C1, NR3C2, PGR, PIM1, POLA1, PPARA, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.45761 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, SMAD3, SRC, TEK |
2.45683 |
|
[BP] GO:0045927 |
positive regulation of growth
|
ALOX12, BCL2, CSNK2A1, EGFR, ERBB2, F2, INSR, PIM1 |
2.45157 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, F2, SMAD3, SRC, TERT |
2.44903 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, SRC |
2.43689 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, DRD3, ESR1, ESR2, ESRRA, FABP4, GPER1, HSPA1A, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
2.43382 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
ALOX12, CYP1B1, ERBB2, F3, GPER1, KDR, TEK, TERT, XDH |
2.43037 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.42319 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.42319 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX12, ALOX15, ALOX5 |
2.42319 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRB1, EGFR, GPER1, HTR2A, HTR2B |
2.41864 |
|
[BP] GO:0045944 |
None
|
APP, AR, DRD3, EGFR, ESR1, ESRRA, ESRRB, GPER1, MET, MMP12, NR3C1, PGR, PPARA, SMAD3, TERT, TNKS, TOP2A |
2.41034 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.41034 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.41034 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.41034 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.41034 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.41034 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRB1, EGFR, GPER1, HTR2A, HTR2B |
2.41034 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.3786 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD3, EGFR, MTNR1A, MTNR1B, PPARA, RORC |
2.35945 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.35486 |
|
[BP] GO:0051209 |
None
|
HTR2A, HTR2B, HTR2C, TRPV1 |
2.34443 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.34443 |
|
[BP] GO:0051283 |
None
|
HTR2A, HTR2B, HTR2C, TRPV1 |
2.34443 |
|
[BP] GO:0042058 |
None
|
ADORA1, APP, EGFR, GPER1, MMP9 |
2.33526 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, AR, EGFR, ESR1, FLT3, GPER1, INSR, NR3C1, SRC |
2.33506 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRB1, AR, CACNA1C, CNR1, DRD3, ESR2, HTR2A, HTR2C, HTR6, MTNR1B, PGR, TEK |
2.33489 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, EGFR, ERBB2, FLT3, HTR2A, HTR2B, INSR, MIF, PTPN1, SRC |
2.31743 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1 |
2.31593 |
|
[BP] GO:0090342 |
None
|
CDK6, MIF, NUAK1, TERT |
2.31279 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GPER1, IGF1R, INSR, MMP2, SRC, TRPV1 |
2.31216 |
|
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, SRC |
2.31216 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.31216 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, AR, BCL2, CSNK2A1, EGFR, ERBB2, F2, GPER1, PTPN1, SMAD3, SRC, TERT |
2.309 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, GPER1, HCAR2, MMP9, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.309 |
|
[BP] GO:0051341 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
2.29818 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.29291 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.29291 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HSD11B2, SRC, TRPV1, TYR |
2.28443 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD3, INSR, TERT |
2.27416 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, GPER1, HCAR2, MMP9, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.27416 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, EGFR, F2, FUT7, HTR2B, HTR6, KDR, MET, MIF, MMP1, MMP12, MMP9, SRC, TEK |
2.25746 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, EGFR, F2, FUT7, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, SRC, TEK |
2.25433 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.25415 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, GPER1, MMP9, SMAD3, SRC, XDH |
2.25302 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, SRC |
2.24659 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.24025 |
|
[BP] GO:0010628 |
positive regulation of gene expression
|
APP, AR, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSPA1A, INSR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.24 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, FABP3, FABP4, FUT7, GBA2, HSPA1A, MAOA, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
2.23847 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, EGFR, GPER1, HCAR2, HTR2B, MIF, MMP12, SRC |
2.23356 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GPER1, IGF1R, INSR, SRC |
2.23333 |
|
[BP] GO:0016048 |
None
|
ADORA1, HTR2A, TRPV1 |
2.23333 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.23333 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.23333 |
|
[BP] GO:2000351 |
None
|
GPER1, KDR, TEK, TERT |
2.22662 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B |
2.22662 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRB1, AR, CNR1, DRD3, ESR2, HTR2A, HTR2C, HTR6, MTNR1B, PGR, TEK |
2.20264 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9 |
2.19172 |
|
[BP] GO:0051704 |
multi-organism process
|
APP, AXL, BCL2, CDK6, CYP1A1, DRD3, EGFR, F2, HSD11B2, HSPA1A, HTR2A, INSR, KDR, MET, MMP1, MMP12, POLA1, SMAD3, SRC |
2.18506 |
|
[BP] GO:0016311 |
None
|
ALPL, APEX1, BCL2, CA3, CDC25B, DUSP3, POLB, PTPN1 |
2.18465 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRB1, AKR1B1, APP, BCL2, CNR1, CNR2, CYP1B1, DRD3, EGFR, GPER1, HSD11B2, HTR2A, HTR2B, INSR, SRC, TEK, TRPV1, TYR |
2.18263 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.17817 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F2, F3, FABP4, FLT3, GPER1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MIF, MMP9, NUAK1, PTPN1, SMAD3, SRC, TEK, XDH |
2.17359 |
|
[BP] GO:0009266 |
None
|
ADORA1, ADRB1, HSPA1A, HTR2A, HTR2B, TRPV1 |
2.1664 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.16015 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.16015 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.16015 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.16015 |
|
[BP] GO:0002695 |
negative regulation of leukocyte activation
|
AXL, CNR1, CNR2, DUSP3, ERBB2, GPER1 |
2.15784 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.15342 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.14559 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA |
2.14559 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.14559 |
|
[BP] GO:0051345 |
None
|
ADRB1, APP, EGFR, ERBB2, ESR1, F3, GPER1, HSPA1A, HTR2A, HTR2B, PTPN1, SMAD3, XDH |
2.14133 |
|
[BP] GO:1905475 |
None
|
AR, BCL2, CSNK2A1, EGFR, ERBB2, GPER1 |
2.13225 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, HSPA1A, MIF, MMP9, NUAK1, POLA1, POLB, PTPN1, SRC, TERT, TOP2A, TRPV1 |
2.1229 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
ALOX12, CYP1B1, F3, KDR, TEK, TERT |
2.11952 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD3, PPARA, RORC, TOP2A |
2.11952 |
|
[BP] GO:0098900 |
None
|
CACNA1C, CNR1, CNR2, GPR35 |
2.11952 |
|
[BP] GO:0048146 |
positive regulation of fibroblast proliferation
|
CDK6, EGFR, ESR1, MIF |
2.11952 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.11952 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, EGFR, ESR1, MTNR1A, PGR, SRC |
2.11249 |
|
[BP] GO:2001236 |
regulation of extrinsic apoptotic signaling pathway
|
AR, BCL2, GPER1, HSPA1A, SRC, TERT |
2.10859 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.0925 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.0925 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, SRC |
2.08978 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, EGFR, HSPA1A, IGF1R, MET, MIF, NUAK1, PTPN1, TERT, XDH |
2.08967 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, F2, FLT3, FUT7, HSPA1A, MIF, MMP9, RORC, SMAD3, SRC, TRPV1 |
2.08733 |
|
[BP] GO:0000904 |
cell morphogenesis involved in differentiation
|
AR, AXL, MET, SRC, TEK |
2.08733 |
|
[BP] GO:0090344 |
None
|
CDK6, MIF, TERT |
2.07726 |
|
[BP] GO:0022612 |
gland morphogenesis
|
BCL2, EGFR, POLB |
2.07726 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.07726 |
|
[BP] GO:0051194 |
None
|
ESRRB, HTR2A, INSR |
2.07726 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.07726 |
|
[BP] GO:0050995 |
None
|
ADORA1, CNR1, HCAR2 |
2.07726 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTPN1, SRC |
2.07485 |
|
[BP] GO:0030307 |
positive regulation of cell growth
|
ALOX12, BCL2, CSNK2A1, EGFR, ERBB2, F2 |
2.07485 |
|
[BP] GO:0051336 |
regulation of hydrolase activity
|
ADRB1, APP, CSNK2A1, EGFR, ERBB2, ESR1, F3, GPER1, HSPA1A, HTR2A, HTR2B, MMP9, NUAK1, PTPN1, SMAD3, SRC, XDH |
2.06891 |
|
[BP] GO:0010629 |
None
|
APP, AR, AURKB, DRD3, ESR1, ESR2, ESRRA, FABP4, GPER1, HSPA1A, KDR, MIF, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TERT, TRPV1, XDH |
2.05145 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, MMP9, TERT |
2.04242 |
|
[BP] GO:2001237 |
negative regulation of extrinsic apoptotic signaling pathway
|
AR, BCL2, HSPA1A, SRC, TERT |
2.03642 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, POLB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.03531 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, POLB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.03531 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ERBB2, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NR3C1, NUAK1, PIM1, POLB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.03477 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, GPER1, HCAR2, MMP9, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.03043 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.02643 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.02365 |
|
[BP] GO:0097553 |
None
|
HTR2A, HTR2B, HTR2C, TRPV1 |
2.01999 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.01999 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.01999 |
|
[BP] GO:0009653 |
anatomical structure morphogenesis
|
APP, AR, AXL, BCL2, CA2, CA9, CACNA1C, CYP1B1, EGFR, ESR1, HTR2B, INSR, MET, MMP2, POLB, SMAD3, SRC, TEK |
2.01619 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX12, ALOX15, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CNR1, CNR2, CSNK2A1, DRD3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, GBA2, GLO1, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP2, MTNR1A, MTNR1B, PIM1, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
5.39643 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRB1, APP, AXL, CA4, CNR1, CNR2, DRD3, F10, F3, FLT3, GPER1, GPR35, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
5.11825 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX12, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAOA, MET, MMP2, MTNR1A, MTNR1B, NR3C2, PGR, PIM1, PTGES, PTPN1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
5.08883 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRB1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCL2, CA1, CA2, CA3, CA4, CA5A, CA5B, CA7, CACNA1C, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, F10, F2, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, INSR, KDR, MAOA, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, POLA1, PTGES, PTPN1, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.40277 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ADRB1, ALOX15, APP, AXL, CA2, CA4, CA9, CACNA1C, CNR1, CNR2, DRD3, DUSP3, EGFR, ERBB2, F10, F2, F3, FLT3, GPER1, GPR35, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, SRC, TEK, TRPV1 |
4.33107 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRB1, APP, AXL, CNR1, CNR2, DRD3, FLT3, GPER1, GPR35, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
3.86395 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, F10, F2, FLT3, GBA2, GPER1, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGES, PTPN1, TBXAS1 |
3.41354 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ADRB1, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, F10, F2, F3, FLT3, FUT7, GBA2, GPER1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAOA, MET, MTNR1A, MTNR1B, NR3C2, PTGES, PTPN1, SRC, TBXAS1, TEK, TRPV1, TYR |
3.3265 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.24098 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, GBA2, GPER1, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGES, TBXAS1 |
2.72213 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, ERBB2, GPER1, HSPA1A, PTGES, SRC, TNKS2, TYR |
2.61058 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, ERBB2, TEK |
2.47764 |
|
[CC] GO:0032589 |
None
|
ADORA1, GPER1, INSR, TRPV1 |
2.47603 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.17359 |
|
[CC] GO:0045121 |
membrane raft
|
APP, CNR1, EGFR, HTR2A, INSR, KDR, SRC, TEK |
2.11521 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, CNR1, EGFR, HTR2A, INSR, KDR, SRC, TEK |
2.09746 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
22.814 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
17.982 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
17.0199 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, HTR2A, HTR2B, HTR2C, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
13.1916 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, NR3C1, NR3C2, PGR, PPARA, RORC, TEK, TRPV1 |
12.9449 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
12.569 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PTPN1, RORC, SMAD3, TNKS |
12.4586 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DUSP3, EGFR, ERBB2, F10, F2, F3, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, POLA1, POLB, PTGES, PTPN1, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
12.4214 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC, SHBG |
11.9178 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CDK6, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, NR3C1, NR3C2, PGR, PPARA, RORC, TEK, TRPV1 |
11.8422 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, NR3C1, NR3C2, PGR, PPARA, RORC, TEK, TRPV1 |
11.5156 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.2138 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRB1, AR, AXL, CNR1, CNR2, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, NR3C1, NR3C2, PGR, PPARA, RORC, SMAD3, TEK, TRPV1 |
11.0729 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, NR3C2, PGR, PPARA, RORC |
10.946 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.7343 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, GPER1, HSD17B1, IGF1R, INSR, MTNR1A, NQO2, NR3C1, SHBG |
9.27625 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1, POLB |
9.20215 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
8.68637 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PGR, PPARA, RORC |
8.68637 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, GPER1, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, RORC, SHBG, TRPV1 |
8.42729 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, TEK |
7.87302 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MAOA, NQO2, TBXAS1, TYR, XDH |
7.87302 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, XDH |
7.71986 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, TEK |
7.00653 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, DRD3, EGFR, ERBB2, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIM1, PPARA, SRC, TEK, TOP2A, TRPV1 |
6.55006 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRB1, AXL, CNR1, CNR2, DRD3, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
6.38118 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRB1, AXL, CNR1, CNR2, DRD3, EGFR, ERBB2, F3, FLT3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
6.38118 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
6.07209 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, TYR |
5.17807 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, HSD11B2, HSD17B1, NQO2, POLA1, PTGES, SRC, TBXAS1, XDH |
5.13719 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.13052 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, ERBB2, INSR, KDR |
4.89992 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
4.79905 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, SRC, TBXAS1 |
4.3102 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
4.12625 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, ADRB1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, HSD11B2, HSD17B1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MTNR1A, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SHBG, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, XDH |
4.12022 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, SRC, TBXAS1 |
4.08648 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRB1, APP, AR, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRB, F3, HSPA1A, MET, MIF, NR3C1, PGR, POLA1, POLB, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.98873 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2, GPER1 |
3.86395 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TBXAS1, TYR |
3.76098 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
3.69164 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13 |
3.47817 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
3.37537 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
3.37419 |
|
[MF] GO:0004993 |
None
|
HTR2A, HTR2B, HTR2C, HTR6 |
3.26347 |
|
[MF] GO:0099589 |
None
|
HTR2A, HTR2B, HTR2C, HTR6 |
3.26347 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, POLA1, POLB, SRC, TEK, TERT |
3.25213 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.07621 |
|
[MF] GO:0008227 |
None
|
ADRB1, HTR2A, HTR2B, HTR2C, HTR6 |
3.04079 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, EGFR, ERBB2, ESR1, ESR2, FLT3, IGF1R, KDR, MET, MIF, MMP9, NQO2, PGR, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
2.96904 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.96713 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.88734 |
|
[MF] GO:0043176 |
None
|
HTR2A, HTR2B, HTR2C |
2.85491 |
|
[MF] GO:0051378 |
None
|
HTR2A, HTR2B, HTR2C |
2.85491 |
|
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, ADRB1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DRD3, DUSP3, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RORC, SHBG, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.85215 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.82148 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.80416 |
|
[MF] GO:0047977 |
hepoxilin-epoxide hydrolase activity
|
ALOX12, ALOX15 |
2.80416 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.80416 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.80416 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.80416 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, ERBB2, MET, PPARA, PTPN1, SMAD3 |
2.77701 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6 |
2.75324 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.62289 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD3, HTR2A, HTR2B, HTR2C |
2.61459 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, EGFR, ERBB2, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD11B2, HSD17B1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, XDH |
2.6097 |
|
[MF] GO:0099528 |
None
|
HTR2A, HTR2B, HTR2C, HTR6 |
2.583 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
ADRB1, EGFR, ERBB2, INSR, KDR, SMAD3 |
2.57523 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.52781 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRB1, CNR1, CNR2, DRD3, GPER1, GPR35, HCAR2, HTR2A, HTR2B, HTR2C, HTR6, MTNR1A, MTNR1B |
2.46209 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, ERBB2, IGF1R, INSR, KDR, TEK |
2.44903 |
|
[MF] GO:0008502 |
None
|
MTNR1A, MTNR1B |
2.41034 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.41034 |
|
[MF] GO:0004052 |
arachidonate 12-lipoxygenase activity
|
ALOX12, ALOX15 |
2.41034 |
|
[MF] GO:0051120 |
hepoxilin A3 synthase activity
|
ALOX12, ALOX15 |
2.41034 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.3786 |
|
[MF] GO:0043168 |
anion binding
|
ALOX15, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, EGFR, ERBB2, F10, F2, F3, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIM1, PTGES, SRC, TEK, TOP2A, TRPV1, XDH |
2.33526 |
|
[MF] GO:0017171 |
serine hydrolase activity
|
ACHE, F10, F2, F3, MMP1, MMP12, MMP2, MMP9 |
2.19269 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.17359 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.16015 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.16015 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.16015 |
|
[MF] GO:0016853 |
None
|
ALOX12, ALOX15, MIF, PTGES, TBXAS1, TOP2A |
2.15784 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR2A, HTR2B, HTR2C |
2.14559 |
|
[MF] GO:0031072 |
heat shock protein binding
|
ADORA1, CSNK2A1, HSPA1A, KDR, NR3C1 |
2.00563 |
