| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CHRM1, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GAA, GBA, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KDR, KIT, MAOA, MET, MIF, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS1, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
23.0119 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ABCG2, ADORA2A, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IDO1, IGF1R, INSR, KDR, KIT, MMP2, MMP9, MPO, PIK3CA, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TOP1, TYR |
19.3006 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
18.0354 |
|
[BP] GO:0010033 |
response to organic substance
|
ADORA2A, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IDO1, IGF1R, INSR, KDR, KIT, MMP2, MPO, PIK3CA, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
17.352 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, GBA, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HTR1B, HTR5A, IDO1, IGF1R, INSR, MMP2, MMP9, MPO, PIK3CA, POLB, PPARA, PPARD, PTGES, PTGS2, RORC, SRC, TEK, TYR |
16.8913 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GBA, GPR35, GRM1, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.6247 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GBA, GPR35, GRM1, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.6031 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
15.9243 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
15.8171 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, APP, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IDO1, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARD, PRKCA, PTGES, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
15.3127 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, ADORA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSPA1A, HTR2B, HTR2C, IDO1, MIF, MPO, PIK3CA, PIM1, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1, TYR, XDH |
15.242 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, ESR1, FABP3, FABP4, FUCA1, FUT7, GBA, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1 |
14.83 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5947 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5947 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GBA, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.3552 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GBA, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.0852 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADORA2A, ADRA1A, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, PTGS2 |
13.9386 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADORA2A, ADRA1A, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, PTGS2 |
13.9386 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.7578 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, ADORA2A, CNR1, DRD1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, PTGS2 |
12.9237 |
|
[BP] GO:0099536 |
None
|
ADORA2A, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
12.9142 |
|
[BP] GO:0099537 |
None
|
ADORA2A, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
12.9142 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GBA, GRIK5, GRM1, GRM5, HIF1A, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IDO1, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP1, TOP2A, TYR |
12.8833 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AXL, BCL2, CHRM1, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GAA, GBA, GRM1, GRM5, GRM8, HIF1A, HMGCR, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IDO1, IGF1R, INSR, KIT, MET, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, PIK3CA, PIM1, PPARA, PPARD, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TOP1, TYR |
12.6296 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, ADORA2A, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GBA, GLO1, GRIK5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
12.5531 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, ABCG2, ADORA2A, ADRA1A, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, FABP3, GBA, HMGCR, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KDR, POLB, PTGS2, SRC, TOP1 |
12.4823 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GBA, GPR35, GRIK5, GRM1, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, PHF8, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
12.432 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PPARD, PTGS2, SRC, TEK |
12.3851 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
12.3851 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, ADORA2A, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PPARD, PRKCA, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
12.3227 |
|
[BP] GO:0007268 |
None
|
ADORA2A, CHRM1, CHRM2, CHRM4, DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
12.1356 |
|
[BP] GO:0098916 |
None
|
ADORA2A, CHRM1, CHRM2, CHRM4, DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1 |
12.1356 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
11.9563 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA2A, ADORA3, APEX1, APP, BCL2, CDK6, CHRM1, CHRM4, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, HIF1A, HTR1D, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PPARD, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
11.9424 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, GAA, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MAOA, MPO, NQO2, PHF8, PPARD, PTGS1, PTGS2, TBXAS1, TYR, XDH |
11.8809 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, ADORA2A, AURKB, BCL2, CA2, CA7, CDK6, CNR1, DRD1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PIK3CB, PTGS2, SRC, TNKS, TNKS2 |
11.8035 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.7452 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, GBA, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
11.7328 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.6465 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
11.6082 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IDO1, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.5016 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PPARD, PTGS2 |
11.4357 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PPARD, PTGS2 |
11.4357 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, PIM1, PPARD, PRKCA, PTGS2, TEK, TERT |
11.2971 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, ADORA2A, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GBA, GLO1, HIF1A, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
11.2317 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
11.219 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, HSD11B2, HSD17B2, HTR1B, HTR5A, IDO1, MPO, PPARD, PTGES, PTGS2, RORC, SRC, TYR |
11.1709 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, ADORA2A, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MIF, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PPARD, PRKCA, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
11.1709 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, ADRA1A, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, FLT3, GAA, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, POLA1, POLB, SMAD3, SRC, TERT |
11.1701 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ADORA2A, ALPL, APEX1, APP, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FLT3, GBA, HSD11B2, HTR1B, HTR5A, PTGES, PTGS2, RORC, SRC, TEK, TYR |
11.1085 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, FABP3, FABP4, FUCA1, FUT7, GBA, GBA2, HMGCR, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1 |
11.1021 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PPARD, PTGS2 |
11.0871 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GBA, GPR35, GRIK5, GRM1, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, PHF8, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
11.0492 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PPARD, PTGS2 |
11.0492 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.0316 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.0316 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA2A, ADORA3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA7, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, GPR35, GRIK5, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
10.8146 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, ADORA2A, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HIF1A, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIM1, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
10.7821 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, APP, AXL, BCL2, CA1, CA2, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PPARD, PRKCA, PTGES, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2 |
10.5988 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PPARD, PTGS2, SRC, TEK |
10.5988 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA2A, ADORA3, ADRA1A, APP, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, SIGMAR1, SRC |
10.5168 |
|
[BP] GO:0097756 |
None
|
ADORA1, ADRA1A, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
10.5058 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PPARD |
10.3989 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, ADORA2A, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, HTR2C, PPARD, PRKCA |
10.3906 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, ADORA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
10.3389 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1, TEK |
10.1722 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, ADORA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP1, MMP2, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
10.0858 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADORA2A, ADRA1A, AXL, BCL2, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, DRD3, ESR2, GBA, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PTGS2, SLC1A1, TEK |
10.0421 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, GBA, GRM1, HIF1A, HMGCR, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, KIT, MMP2, MPO, POLB, PPARA, PPARD, PTGS2, SMAD3, SRC, TEK, TERT, TYR |
9.96844 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, ADORA2A, ADRA1A, CA2, CA7, CNR1, CNR2, DRD2, HTR1B |
9.72805 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPR35, GRM3, GRM8, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, MPO, PHF8, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
9.70266 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, MPO, PHF8, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PPARD, PRKCA, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
9.70042 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PHF8, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
9.59655 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DAO, DRD1, DRD2, DRD3, GBA, GBA2, HIF1A, HMGCR, HTR1A, MAOA, PPARD, TYR |
9.47806 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, ADORA2A, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HIF1A, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MIF, MMP9, MPO, PIK3CA, PIM1, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.47797 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA1A, AKR1B1, ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, GRM5, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, KIT, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
9.47797 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.33283 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, ADRA1A, AKR1B1, APP, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, GBA, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, SMAD3 |
9.18278 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADORA2A, ADRA1A, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, SLC1A1, TEK |
9.18085 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PPARD, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
9.11934 |
|
[BP] GO:0007610 |
None
|
ADORA2A, APP, BCL2, CNR1, DRD1, DRD2, DRD3, EGFR, GAA, GRM1, GRM5, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IDO1, INSR, KIT, PPARA, PTGS2 |
9.05272 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ADORA2A, ALOX15, APP, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CYP19A1, DRD1, DRD2, DRD3, EGFR, GPR35, GRIK5, GRM5, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, MIF, MMP12, MMP9, PIK3CB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TERT |
9.03027 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
9.01219 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GBA, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
9.01101 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PPARD, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
9.0008 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, AURKB, BCL2, CDC25B, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PHF8, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.99128 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
8.94967 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
8.78635 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
8.72688 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA1A, ALOX15, APP, DRD2, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, PIK3CB, PRKCA, PTPN1, SRC, TEK, XDH |
8.69673 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
8.67432 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, HIF1A, KDR, KIT, MMP9, PTGES, PTGS2, SRC, TERT |
8.65495 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GPR35, GRM3, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, MPO, PHF8, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.63319 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA2A, ADORA3, ADRA1A, APP, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GBA, GRM1, GRM3, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.41442 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, ADORA2A, APP, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, GBA, HIF1A, HMGCR, HSPA1A, IDO1, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
8.38644 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PHF8, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.38496 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, APP, BCL2, CHRM1, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, EGFR, GAA, GRM1, GRM5, GRM8, HIF1A, HMGCR, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, KIT, PIK3CA, PPARD, PTGS2, SRC, TEK, TYR |
8.38459 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1 |
8.38324 |
|
[BP] GO:0050795 |
None
|
ADORA1, ADORA2A, CNR1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
8.38324 |
|
[BP] GO:0007200 |
None
|
ADRA1A, CHRM1, CHRM2, CHRM4, DRD1, DRD2, ESR1, GRM5, HTR2A, HTR2B, HTR2C |
8.35892 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PPARD, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
8.35528 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1 |
8.2375 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, MMP9, PIK3CA, PPARD, PTGS2, RORC, SMAD3, SRC, TERT |
8.22089 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA1A, ALOX15, APP, DRD2, DUSP3, EGFR, FLT3, GBA, GRM1, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, PIK3CB, PRKCA, PTPN1, SRC, TEK, XDH |
8.20569 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA1A, AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GBA, HSD11B2, HTR1B, HTR5A, INSR, KIT, PPARA, PTGS2, SRC, TEK |
8.19431 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GBA, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PHF8, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.17988 |
|
[BP] GO:0009636 |
response to toxic substance
|
ADORA2A, AKR1B1, ALPL, APEX1, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, HMGCR, HTR1B, HTR1D, KDR, POLB, SRC |
7.98128 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
ADORA2A, AURKB, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, HCAR2, HIF1A, PIK3CB, PTGS2, TNKS, TNKS2 |
7.95536 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM5, HIF1A, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, PIK3CA, PPARD, PTGS2, RORC, SMAD3, SRC |
7.93363 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA2A, ADORA3, ADRA1A, APP, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GAA, GBA, GPR35, GRM1, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IDO1, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PPARD, PRKCA, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
7.89824 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
7.84162 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
7.81972 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, DUSP3, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PRKCA, PTPN1, SRC, TEK |
7.79799 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ADORA2A, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARD, PRKCA, PTGS2, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
7.79799 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA2A, ADORA3, ADRA1A, CHRM1, CHRM2, DRD2, DRD3, EGFR, GAA, GBA, GPR35, GRM1, HCAR2, HTR2A, HTR2C, KIT, PRKCA, PTGS2, SLC1A1, SMAD3 |
7.79799 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PRKCA, SRC, TEK |
7.73294 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, ADORA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
7.73231 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GBA, GPR35, GRM1, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.65866 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADORA2A, ADRA1A, ALOX15, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PPARD, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
7.63367 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, XDH |
7.50036 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ADORA2A, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, GBA, HMGCR, IDO1, KDR, MET, MIF, MMP12, PPARA, PPARD, PRKCA, PTGS2, SMAD3, TEK |
7.4661 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA1A, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
7.38777 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SRC, TEK, XDH |
7.3655 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.36266 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
7.34644 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GBA, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.30579 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADORA2A, ADRA1A, APP, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, GBA, HCAR2, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, IDO1, KDR, KIT, MET, MIF, MMP12, MMP9, PIM1, PRKCA, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT |
7.2856 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GBA, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.26369 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ADORA2A, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARD, PRKCA, PTGS2, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
7.23442 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, SRC, TEK |
7.10873 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
7.10873 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.0305 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
7.0305 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
ADORA2A, AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
7.02827 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, DRD3, FABP3, FLT3, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, KIT, PPARA, PTGS2, RORC, SRC, TEK |
6.97783 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, ADORA2A, AKR1B1, ALPL, AOX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUCA1, FUT7, GBA, GBA2, GLO1, HIF1A, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PHF8, PIK3CA, PIM1, POLB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
6.94038 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CHRM1, CNR1, DRD1, DRD2, DRD3, EGFR, GRM5, HIF1A, HMGCR, HTR2A, INSR, KIT, PTGS2 |
6.92739 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA2A, ADORA3, ADRA1A, APP, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GBA, GPR35, GRM1, GRM3, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.9263 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
6.9263 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, EGFR, HSPA1A, IDO1, MAOA, MPO |
6.91332 |
|
[BP] GO:0042310 |
None
|
ADRA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
6.89675 |
|
[BP] GO:1900542 |
None
|
ADORA2A, DRD1, DRD2, DRD3, ESRRB, GRM3, GRM8, HIF1A, HTR1B, HTR1E, HTR2A, INSR, PPARA, PRKCA |
6.82449 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA1A, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, GPR35, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
6.81116 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA1A, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, GPR35, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
6.78339 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, ADRA1A, APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GAA, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, POLA1, SMAD3 |
6.76765 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, DYRK1A, EGFR, ESR1, HTR7, KIT, PPARA, RORC, SRC, TOP1, TOP2A |
6.69371 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, DRD1, EGFR, F10, F3, HIF1A, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
6.69293 |
|
[BP] GO:0006140 |
None
|
ADORA2A, DRD1, DRD2, DRD3, ESRRB, GRM3, GRM8, HIF1A, HTR1B, HTR1E, HTR2A, INSR, PPARA, PRKCA |
6.67469 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
6.65145 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, GBA, GRIK5, GRM1, GRM5, HIF1A, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MIF, MMP2, MMP9, NUAK1, PIK3CA, POLA1, POLB, PPARD, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A |
6.61866 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, ADORA2A, APEX1, APP, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GRM3, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
6.59839 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, GBA, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PPARD, PTGES, PTGS1, PTGS2 |
6.59839 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.56791 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, POLB, PPARA, PPARD, PTGS2, SMAD3, SRC, TEK, TERT |
6.56738 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GBA, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
6.54555 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, ADORA2A, CNR1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PPARD, PRKCA, SRC |
6.51364 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, ADORA2A, BCL2, CA2, CA7, DRD1, DRD2, DRD3, HTR2A, HTR2B, HTR2C, KDR, SRC |
6.48698 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
ADORA2A, AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
6.42566 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, ADORA2A, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRIK5, HTR1A, INSR, MAOA, PTGS2, SLC1A1, SMAD3 |
6.38423 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, ADRA1A, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HIF1A, HSD11B1, HSD17B2, INSR, KDR, KIT, PHF8, PIK3CA, POLB, PPARA, PPARD, SMAD3, SRC, TEK, TYR |
6.38423 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, MPO, PIM1, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
6.38052 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, ADORA2A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
6.35387 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DAO, DRD1, DRD2, DRD3, HTR1A, MAOA, TYR |
6.35062 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
ADRA1A, BCL2, DRD2, DRD3, DUSP3, DYRK1A, ESR1, GBA, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP9, PTGS2, PTPN1, SRC, XDH |
6.31978 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PPARD, PTGS2, SMAD3, SRC, TEK, TERT |
6.30897 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
6.26594 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA6, CA7, CA9 |
6.25067 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, ADORA2A, CNR1, CYP19A1, DRD2, EGFR, HCAR2, HIF1A, HMGCR, HTR1A, HTR2A, HTR2C, PPARD, PRKCA |
6.23416 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, ALOX15, ALPL, APP, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FLT3, GAA, GBA2, HIF1A, HSD11B1, HSD17B2, HTR5A, INSR, KDR, KIT, MMP9, PHF8, PIK3CA, PIM1, POLB, PPARA, PPARD, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
6.22197 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, HTR2A, HTR2B, HTR2C, MIF, SRC, TNKS, TNKS2 |
6.1873 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, ADORA2A, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
6.17426 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HIF1A, HSD11B2, MMP2, PPARA, PPARD, PTGS2, SMAD3, SRC, TEK, TERT |
6.15858 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, GRIK5, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, SMAD3 |
6.15115 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, BCL2, CHRM1, CHRM4, CYP1A1, EGFR, ESR1, FLT3, HTR1A, KIT, MET, MIF, PIK3CB, PIM1, POLA1, PPARD, SRC, TEK, TYR |
6.14156 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGES, PTGS1, PTGS2, TBXAS1 |
6.13054 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, ADORA2A, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PTPN1, SRC |
6.09743 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADORA2A, ADRA1A, ALOX15, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PPARD, PTGS2 |
6.09004 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, PIM1, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
6.09004 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, HIF1A, KIT, MMP9, PTGES, PTGS2, TERT |
6.0835 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, SRC, TEK, TNKS, TOP1 |
6.02681 |
|
[BP] GO:0007568 |
aging
|
ADRA1A, APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, HTR2A, MIF, MPO, POLB, PTGS2, TERT |
5.99184 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, ADORA2A, CNR1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HIF1A, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PPARD, PRKCA, SRC |
5.99184 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, ADORA2A, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
5.97861 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA2A, ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, FABP4, GBA, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PTGS2, PTPN1, SRC, TNKS |
5.97422 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
5.97012 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, ADORA2A, APP, BCL2, CA2, CA7, CHRM1, CNR1, DRD1, DRD2, DRD3, GPR35, GRM5, HTR1A, HTR1B, HTR2A, MIF, MMP9, PTGS2 |
5.96589 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, ADORA2A, CNR2, CYP19A1, DRD1, DRD2, DRD3, GBA, HMGCR, MIF, PPARA, PPARD, SMAD3, TEK |
5.94697 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DAO, FABP3, GBA2, GLO1, HIF1A, IDO1, MIF, MPO, PIM1, PPARA, PPARD, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
5.93453 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD1, DRD2, DRD3, EGFR, GRM5, HIF1A, HMGCR, HTR2A, INSR, KIT, PTGS2 |
5.9192 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, ADORA2A, APP, CA2, CHRM1, CNR1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, HTR2B, HTR2C, MIF, MMP12, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC |
5.89421 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADORA2A, ADRA1A, APP, CA2, CA7, DRD1, DRD2, EGFR, PTGS2 |
5.85888 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, PIM1, SRC, TEK |
5.84298 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD1, DRD2, HTR1B, HTR2A, PTGS2 |
5.82071 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, ADORA2A, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, DRD1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HTR2B, INSR, MIF, MMP12, PPARD, PTGS2, SMAD3, SRC, TERT |
5.81135 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PPARA, PTGS2, SRC, TEK |
5.79742 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.75056 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.74368 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, ADORA2A, CNR1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, HTR2B, HTR2C, MIF, MMP12, PPARD, PRKCA, SRC |
5.69622 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, XDH |
5.68384 |
|
[BP] GO:0042391 |
None
|
ADORA1, ADORA2A, ADRA1A, APP, BCL2, CNR1, CNR2, DRD1, GBA, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC |
5.64291 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
ADORA2A, APEX1, APP, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GBA, GRM3, GRM8, HIF1A, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
5.5888 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.58763 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA2A, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, GBA, HIF1A, HSD11B2, HSPA1A, HTR1A, HTR2C, IDO1, KIT, MIF, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PPARD, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A |
5.56273 |
|
[BP] GO:1900543 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PPARA, PRKCA |
5.481 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, ADORA2A, CNR2, CYP19A1, DRD2, GBA, MMP12, PPARA, PPARD, SMAD3, TEK |
5.48029 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, HSPA1A, IDO1, MAOA, MGAM, MMP1, MMP12, MMP2, MMP9, MPO, PIK3CB, PPARD, SRC, XDH |
5.46376 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, SRC, TEK |
5.4393 |
|
[BP] GO:0045980 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PPARA, PRKCA |
5.4393 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A, HMGCR, KIT |
5.42327 |
|
[BP] GO:0030815 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
5.42327 |
|
[BP] GO:0006939 |
None
|
ADRA1A, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7 |
5.42327 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, GRM5, HIF1A, HMGCR, INSR, KIT, PTGS2 |
5.41371 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.40549 |
|
[BP] GO:0030800 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
5.30592 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.30092 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GAA, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, XDH |
5.29679 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HIF1A, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.29324 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD2, DRD3, GPR35, HTR1B, HTR2A, MMP9, PTGS2 |
5.27774 |
|
[BP] GO:0051952 |
None
|
ADORA1, ADORA2A, CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A |
5.27706 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTGS2, TERT |
5.27706 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DAO, DRD1, DRD2, DRD3, GBA, HTR1A, MAOA |
5.23551 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA2A, ADORA3, APP, AXL, BCL2, CA1, CHRM4, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
5.20267 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CDK6, CYP1B1, DNMT1, DRD1, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, PIK3CA, PPARD, PTGS2, RORC, SRC |
5.18385 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.18349 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.18349 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.17249 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.16109 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
5.15228 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A, HMGCR, KIT |
5.15228 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
5.0841 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT |
5.08081 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRA1A, CNR1, DRD2, DRD3, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
5.07629 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, ADORA2A, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, GBA, IDO1, PPARA, PPARD, PTGS2, SMAD3, TEK |
5.06816 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, NQO2, PTGS1, RORC |
5.03943 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, ADORA2A, CNR2, CYP19A1, GBA, PPARA, PPARD, SMAD3, TEK |
5.00964 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
5.00484 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, FUCA1, GBA, GBA2 |
5.00459 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, ADRA1A, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F3, FLT3, GRM1, GRM5, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
4.99844 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, SRC, TEK, TNKS, TOP1 |
4.9864 |
|
[BP] GO:0030814 |
None
|
ADORA2A, DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
4.98609 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, SMAD3 |
4.9414 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.92258 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, ADORA2A, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, GBA, HSPA1A, IDO1, MMP12, MMP2, PPARA, PPARD, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.89895 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT |
4.86856 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA1A, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
4.85252 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
4.80142 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GBA, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.79344 |
|
[BP] GO:2001023 |
None
|
ADORA2A, CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A, MET |
4.79287 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.76077 |
|
[BP] GO:0051588 |
None
|
ADORA2A, DRD1, DRD2, DRD3, GRIK5, HTR1A, HTR1B, HTR2C |
4.75784 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, HMGCR, PPARD |
4.73012 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, ADORA2A, DRD2, EGFR, HCAR2, HIF1A, HTR2B, MIF, MMP12, PPARD, SRC |
4.70982 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, PPARD, SLC1A1 |
4.6927 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.68919 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.68919 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.6831 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.67476 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
ADORA2A, APP, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, HIF1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, PHF8, PPARA, PPARD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
4.67461 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PPARD, PTGS2, TERT |
4.65587 |
|
[BP] GO:0050877 |
None
|
ADORA1, ADORA2A, APP, CHRM1, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, EGFR, GAA, GRM1, GRM5, GRM8, HIF1A, HMGCR, HTR2A, INSR, KIT, PTGS2, TYR |
4.64791 |
|
[BP] GO:0050708 |
None
|
ACHE, ADORA2A, CNR1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, PPARD, PRKCA, SRC |
4.6289 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
4.62601 |
|
[BP] GO:0070201 |
None
|
ACHE, ADORA2A, APP, BCL2, CHRM1, CNR1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC |
4.60976 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.602 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
4.60129 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
4.58876 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
4.57295 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, MIF, PRKCA, SRC, TERT |
4.57208 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, SRC, TEK |
4.52383 |
|
[BP] GO:0030817 |
None
|
ADORA2A, DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.50344 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5 |
4.49379 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, GBA, HCAR2, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PTPN1, SMAD3 |
4.48804 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, FUCA1, GBA, GBA2, PPARD |
4.47811 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.47675 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3, MAOA |
4.44634 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DAO, DRD1, DRD2, DRD3, MAOA |
4.44634 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GBA, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
4.43593 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, ADORA2A, CYP19A1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HTR2B, MIF, MMP12, PPARD, SRC |
4.43544 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, EGFR, PPARA, PPARD, SMAD3 |
4.41931 |
|
[BP] GO:0007626 |
None
|
ADORA2A, APP, DRD1, DRD2, DRD3, GAA, GRM1, GRM5, HTR2C, IDO1 |
4.41931 |
|
[BP] GO:0030818 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.39402 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HIF1A, HTR2B, TERT |
4.39402 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GBA, GLO1, GRM1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.38573 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PPARD, PTGES, PTGS2, SRC |
4.37666 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
ADORA2A, APP, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GBA, HIF1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, PHF8, PPARA, PPARD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
4.37425 |
|
[BP] GO:0051223 |
None
|
ACHE, ADORA2A, APP, CHRM1, CNR1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC |
4.37425 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, HIF1A, HMGCR, KIT |
4.36191 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, CNR1, DNMT1, DRD2, DRD3, ESR1, GBA, HIF1A, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.36191 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PTPN1, SRC |
4.33124 |
|
[BP] GO:0002031 |
None
|
DRD2, DRD3, HTR1B, HTR2B |
4.33124 |
|
[BP] GO:0030799 |
None
|
ADORA2A, DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
4.32433 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, ADORA2A, APP, BCL2, CHRM1, DRD2, EGFR, HCAR2, HIF1A, HTR2B, MIF, MMP12, PPARD, PTGS2, SMAD3, SRC |
4.32433 |
|
[BP] GO:0030803 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.29335 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADORA2A, ADRA1A, AKR1B1, AXL, BCL2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, EGFR, GRM5, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, KIT, MET, MIF, NUAK1, PIK3CA, PIK3CB, POLB, PRKCA, PTPN1, SRC, TEK |
4.28309 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ADORA2A, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HIF1A, HSPA1A, IDO1, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC |
4.27861 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, PRKCA, TERT |
4.27861 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, HMGCR, KIT, PTGS2, TYR |
4.26558 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
4.25656 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, PPARD |
4.25656 |
|
[BP] GO:0050714 |
None
|
ACHE, ADORA2A, DRD2, EGFR, HCAR2, HIF1A, HTR2B, MIF, MMP12, PPARD, SRC |
4.25656 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, ADORA2A, APP, BCL2, CHRM1, CNR1, CSNK2A1, DRD2, DRD3, EGFR, HCAR2, HIF1A, HMGCR, HTR2B, MIF, MMP12, PPARD, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TERT |
4.25656 |
|
[BP] GO:0050433 |
None
|
ADORA2A, CNR1, DRD2, DRD3, HTR1B, HTR2A |
4.2484 |
|
[BP] GO:0001975 |
None
|
ADORA2A, CNR2, DRD1, DRD2, DRD3 |
4.2455 |
|
[BP] GO:0009410 |
None
|
ADORA2A, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, GBA, HTR1B |
4.24008 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
4.2334 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TERT, TNKS, TOP2A |
4.2334 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, MPO, PTGS1, PTGS2, SRC |
4.22743 |
|
[BP] GO:0001775 |
cell activation
|
ADORA2A, ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUCA1, FUT7, GAA, HSPA1A, KIT, MGAM, MIF, MMP9, MPO, PIK3CA, PIK3CB, PRKCA, RORC, SMAD3, SRC |
4.1929 |
|
[BP] GO:1900372 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.15025 |
|
[BP] GO:0030809 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.15025 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT |
4.15025 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PPARD, PTGES, PTGS2, SRC |
4.1128 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.10367 |
|
[BP] GO:0042417 |
None
|
DAO, DRD1, DRD2, DRD3, MAOA |
4.09096 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD2, DRD3, HTR1B, HTR2A |
4.09096 |
|
[BP] GO:0042737 |
drug catabolic process
|
ACHE, CYP1A2, CYP2A6, CYP2D6, CYP3A4, DAO, MAOA, MPO |
4.06849 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, GBA, HSD11B2, HTR1B, PTGS2, SRC |
4.04065 |
|
[BP] GO:0060134 |
None
|
ADORA2A, DRD1, DRD2, DRD3 |
4.04065 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
ADORA2A, ADRA1A, CA2, CA7 |
4.04065 |
|
[BP] GO:0001516 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.04065 |
|
[BP] GO:0046457 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
4.04065 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ADRA1A, ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, GBA, HMGCR, HSD11B2, HTR2A, IDO1, KIT, MMP12, MPO, PPARD, PTGES, PTGS2, SMAD3, SRC, TYR |
4.03337 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, ADORA2A, APP, CHRM1, DRD2, EGFR, HCAR2, HIF1A, HTR2B, MIF, MMP12, PPARD, PTGS2, SMAD3, SRC |
4.02983 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX15, MIF, PTGES, PTGS1, PTGS2 |
4.02345 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, DRD3, GBA, HIF1A, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.01596 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, HIF1A, IDO1, MIF, PIK3CB |
3.98884 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, ADORA2A, CA2, CA7, GRM5, MIF |
3.98884 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, GBA, HTR2A, MET, PIK3CA |
3.97056 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, SRC, TEK |
3.95045 |
|
[BP] GO:0030802 |
None
|
ADORA2A, DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
3.94613 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
3.91314 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR1B, HTR2A |
3.91314 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.88788 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, GBA, HMGCR, HSD11B2, MPO, PPARD, PTGS2, SRC, TYR |
3.88532 |
|
[BP] GO:0032768 |
None
|
CNR1, CNR2, EGFR, HIF1A, HTR2B, TERT |
3.88266 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA2A, ADORA3, ADRA1A, APP, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, IDO1, PPARD, PTGES, PTGS2, SMAD3, TERT, XDH |
3.87727 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA2A, ADORA3, ALOX15, AXL, CNR2, KIT, MIF, PIK3CA, PIK3CB, POLB, PTGES, PTGS1, PTGS2 |
3.85357 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, HIF1A, HMGCR, HTR2A, HTR2C, IDO1, INSR, KDR, KIT, PIM1, PPARD, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT |
3.84471 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, GBA, HMGCR, IDO1, MIF, MPO, PTGES, PTGS1, PTGS2 |
3.81168 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA1A, BCL2, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GBA, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
3.80477 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PRKCA, PTGS2, SRC, TEK |
3.80133 |
|
[BP] GO:0001963 |
None
|
ADORA2A, DRD1, DRD2, DRD3 |
3.79443 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
ADORA2A, APP, AURKB, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HIF1A, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, PHF8, PPARA, PPARD, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
3.78922 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.7785 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, SRC, TEK |
3.77835 |
|
[BP] GO:1902893 |
None
|
HIF1A, PPARA, PPARD, SMAD3, TERT |
3.76325 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM4 |
3.75612 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.75612 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADORA2A, ADRA1A, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GBA, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.74741 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, GBA, HSD11B2, HTR1B, PTGS2, SRC |
3.7235 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT |
3.72176 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6, CYP3A4, PHF8 |
3.72176 |
|
[BP] GO:1900371 |
None
|
ADORA2A, DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
3.71227 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, DYRK1A, EGFR, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCA, SRC, TEK, TNKS, TOP1, TOP2A |
3.69915 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC, SRC |
3.69025 |
|
[BP] GO:0030808 |
None
|
ADORA2A, DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
3.69025 |
|
[BP] GO:0051172 |
None
|
ADORA2A, APEX1, APP, AURKB, CSNK2A1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GBA, GRM3, GRM8, HMGCR, HSPA1A, HTR1B, HTR1E, IGF1R, MIF, MMP12, MMP9, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
3.69002 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.69002 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
3.69002 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, HIF1A, HTR2B, KDR, MMP12, PPARD, PRKCA, SMAD3, TEK, XDH |
3.68585 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CYP1B1, F3, HIF1A, KDR, KIT, PRKCA, PTGS2, TEK, TERT |
3.66104 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, PPARD, RORC, SRC |
3.66104 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.65014 |
|
[BP] GO:0045936 |
None
|
ADORA2A, DRD2, DRD3, DUSP3, FABP4, GBA, GRM3, GRM8, HMGCR, HTR1B, HTR1E, IGF1R, PPARA, PRKCA, PTPN1, XDH |
3.62474 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, GRM5, HTR1B, IGF1R, INSR, MMP2, PTGS2, SRC |
3.62474 |
|
[BP] GO:0010563 |
None
|
ADORA2A, DRD2, DRD3, DUSP3, FABP4, GBA, GRM3, GRM8, HMGCR, HTR1B, HTR1E, IGF1R, PPARA, PRKCA, PTPN1, XDH |
3.61741 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, IDO1, KDR, MET, MIF, PRKCA, PTGS2, SMAD3 |
3.61707 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT |
3.61112 |
|
[BP] GO:0003014 |
None
|
ADORA1, ADORA2A, ADRA1A, AKR1B1, BCL2, DRD2, HSD11B2 |
3.5813 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, HTR1B, KDR, PTGS2, SRC |
3.57864 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, DYRK1A, EGFR, HTR7, PPARA, RORC, TOP1 |
3.56219 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.54369 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, HTR2A, KIT, MIF, PTPN1, SRC |
3.54369 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, SMAD3 |
3.53975 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRA1A, CHRM1, CHRM2, DRD2, EGFR, GAA, HTR2A, PTGS2, SLC1A1 |
3.53975 |
|
[BP] GO:0042752 |
None
|
ADORA1, ADORA2A, DRD2, DRD3, PPARA, RORC, TOP2A |
3.52836 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, GBA, HMGCR, HSD11B2, MPO, PPARD, PTGS2, SRC, TYR |
3.52189 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ADORA2A, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, IDO1, MIF, MMP12 |
3.51212 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, HIF1A, HMGCR, HTR2A, HTR2C, IDO1, INSR, KDR, KIT, MIF, NUAK1, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
3.51212 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
ADORA2A, BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
3.50617 |
|
[BP] GO:0006940 |
None
|
ADORA1, ADRA1A, CHRM1, CHRM2, KIT, PTGS2 |
3.50465 |
|
[BP] GO:0045821 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.497 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR1D, HTR2B |
3.497 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM4 |
3.497 |
|
[BP] GO:0032229 |
None
|
ADORA1, CNR2, HTR1B |
3.497 |
|
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.497 |
|
[BP] GO:0014075 |
None
|
ADORA2A, CNR2, DRD1, DRD2, DRD3 |
3.49393 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADORA2A, ADRA1A, DRD1, DRD2, DRD3, EGFR, GRM5, HTR2B, HTR5A, KDR |
3.49208 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, ESR1, FLT3, GRM5, HTR1B, IGF1R, INSR, KIT, MMP2, PTGS2, SMAD3, SRC |
3.48392 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GRM5, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK |
3.47019 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
ADORA2A, BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
3.46289 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, PPARD, SLC1A1 |
3.4515 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
3.4488 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, PTGS2, RORC, SRC |
3.4488 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, MIF, PIM1, PRKCA, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
3.44808 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
3.44224 |
|
[BP] GO:0045187 |
None
|
ADORA1, ADORA2A, DRD2, DRD3 |
3.41118 |
|
[BP] GO:0051197 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.41118 |
|
[BP] GO:0045913 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA, SRC |
3.40989 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.40989 |
|
[BP] GO:1903532 |
None
|
ACHE, ADORA2A, CYP19A1, DRD2, EGFR, HCAR2, HIF1A, HTR2B, MIF, MMP12, PPARD, SRC |
3.39595 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FABP4, FUCA1, GAA, GBA, GBA2, HSPA1A, IDO1, MAOA, MGAM, MPO, PIK3CB, PPARD, SRC, XDH |
3.37774 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR, IDO1 |
3.37571 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HIF1A, HSD11B2, HSD17B2, IDO1, INSR, KIT, MMP2, MMP9, PPARD, PTGS2, SRC, TOP2A |
3.37215 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HIF1A, HMGCR, KIT, POLB, PTGS2, TYR |
3.35983 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3, HTR2A |
3.32728 |
|
[BP] GO:0035813 |
None
|
ADORA1, ADORA2A, DRD2, DRD3 |
3.32728 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, GRM5, HTR1B, IGF1R, INSR, MMP2, PTGS2, SRC |
3.29979 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, DRD3, PPARA |
3.29979 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DAO, FABP3, FABP4, FUCA1, FUT7, GAA, GBA, GBA2, HSPA1A, IDO1, MAOA, MGAM, PPARD, XDH |
3.29584 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.28827 |
|
[BP] GO:0040016 |
embryonic cleavage
|
PIK3CB, TOP1, TOP2A |
3.28827 |
|
[BP] GO:0009820 |
alkaloid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.28827 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.28827 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GBA, GLO1, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, XDH |
3.25187 |
|
[BP] GO:0051968 |
None
|
ADORA2A, DRD1, EGFR, PTGS2 |
3.24826 |
|
[BP] GO:0042749 |
None
|
ADORA1, ADORA2A, DRD2, DRD3 |
3.24826 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, F3, HIF1A, KDR, PRKCA, PTGS2, TEK, TERT |
3.21626 |
|
[BP] GO:0048167 |
None
|
ADORA1, ADORA2A, APP, DRD1, DRD2, GRM5, KIT, PTGS2 |
3.21626 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, EGFR, HIF1A, HMGCR, HSPA1A, IGF1R, MET, MIF, NUAK1, PTGS2, PTPN1, TERT, XDH |
3.18946 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
3.16859 |
|
[BP] GO:0051194 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
3.16859 |
|
[BP] GO:0097366 |
None
|
ADORA2A, CNR2, DRD1, DRD2, DRD3 |
3.16452 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HIF1A, HSPA1A, INSR, MPO, PIK3CA, PIM1, PPARD, SMAD3, TNKS2 |
3.16013 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.14739 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.14298 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.14298 |
|
[BP] GO:0060078 |
None
|
ADORA1, ADORA2A, GRIA2, GRIA4, GRIK5, GRM5 |
3.12632 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MET, PIK3CA, PPARA, SMAD3 |
3.11228 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.1055 |
|
[BP] GO:0016139 |
None
|
FUCA1, GBA, GBA2 |
3.1055 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.1055 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
ADORA2A, BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
3.1055 |
|
[BP] GO:0003012 |
None
|
ADORA1, ADRA1A, DRD1, DRD2, GAA, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA |
3.10305 |
|
[BP] GO:0044062 |
None
|
ADORA1, ADORA2A, DRD2, DRD3 |
3.10129 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
3.08686 |
|
[BP] GO:2000107 |
negative regulation of leukocyte apoptotic process
|
AURKB, AXL, HIF1A, IDO1, MIF |
3.08552 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.08552 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX15, CYP19A1, CYP3A4, DAO, GBA, HMGCR, TYR |
3.0768 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ADORA2A, ALOX15, BCL2, CDK6, CYP1B1, DUSP3, IDO1, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, SMAD3, SRC, TEK |
3.04765 |
|
[BP] GO:1901570 |
None
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
3.04409 |
|
[BP] GO:0006936 |
None
|
ADRA1A, DRD1, DRD2, GAA, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA |
3.04324 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.03261 |
|
[BP] GO:0007202 |
None
|
ADRA1A, EGFR, HTR2A, HTR2B |
3.03261 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MPO |
3.03261 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, SRC, TNKS, TOP1 |
3.02531 |
|
[BP] GO:0045934 |
None
|
APEX1, AURKB, DNMT1, DRD2, DRD3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, MMP12, PPARA, PPARD, PRKCA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2 |
3.02531 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HIF1A, HSD17B2, INSR, KIT, PPARD, PTGS2, SRC |
3.01889 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, HIF1A, KDR, KIT, POLB, TEK, TYR |
2.99207 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC, SRC |
2.99207 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PPARD, PTGS2, TYR |
2.99207 |
|
[BP] GO:0048169 |
None
|
APP, DRD2, GRM5, KIT |
2.96644 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, HIF1A, IDO1, KIT, PTGS2 |
2.9638 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, HIF1A, INSR, PTGS2, SMAD3, XDH |
2.95821 |
|
[BP] GO:0048143 |
None
|
ADORA2A, APP, EGFR |
2.95273 |
|
[BP] GO:0001973 |
None
|
ADORA1, ADORA2A, ADORA3 |
2.95273 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, ADORA2A, AKR1B1, CHRM1, DRD2, F10, F3, GBA, HIF1A, MET, PRKCA, XDH |
2.95104 |
|
[BP] GO:1901214 |
regulation of neuron death
|
ADORA2A, AXL, BCL2, GBA, GRIK5, HIF1A, PIK3CA, PPARA, SIGMAR1, TERT |
2.93278 |
|
[BP] GO:0046887 |
positive regulation of hormone secretion
|
ADORA2A, CYP19A1, DRD2, EGFR, HCAR2, HIF1A, PPARD |
2.9204 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B, KIT |
2.91267 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
HIF1A, KDR, MET, PRKCA, PTGS2, TEK |
2.91267 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, CNR1, CSNK2A1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESR2, GBA, GRIK5, HIF1A, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PHF8, PIK3CB, PPARD, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.9117 |
|
[BP] GO:0046466 |
None
|
CYP1B1, FUCA1, GBA, GBA2 |
2.9095 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
2.9095 |
|
[BP] GO:0006693 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
2.9095 |
|
[BP] GO:0006692 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
2.9095 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, GRM5, HTR2A, KIT, MIF, PTPN1, SRC |
2.89868 |
|
[BP] GO:0044242 |
None
|
AKR1B10, CYP1B1, FABP3, FABP4, FUCA1, GBA, GBA2, PPARD |
2.89868 |
|
[BP] GO:0001938 |
None
|
F3, HIF1A, HTR2B, KDR, PRKCA, TEK |
2.89069 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, SMAD3, SRC, TERT, TNKS |
2.88623 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
2.8831 |
|
[BP] GO:0050679 |
None
|
EGFR, F3, HIF1A, HTR2B, KDR, MMP12, PRKCA, TEK |
2.8661 |
|
[BP] GO:0098900 |
None
|
ADRA1A, CNR1, CNR2, GBA, GPR35 |
2.85967 |
|
[BP] GO:0007271 |
None
|
ADORA2A, CHRM1, CHRM2, CHRM4 |
2.84985 |
|
[BP] GO:0051341 |
None
|
CNR1, CNR2, EGFR, HIF1A, HTR2B, TERT |
2.84007 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HIF1A, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PTGS2, SRC, TEK |
2.82711 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
BCL2, DRD1, HTR1A, HTR2C, IDO1 |
2.8252 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.82072 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, GBA, HIF1A, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PTPN1 |
2.80972 |
|
[BP] GO:0051482 |
None
|
DRD1, GPR35, GRM1, HTR2C |
2.79148 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.79148 |
|
[BP] GO:0031623 |
None
|
ACHE, DRD2, DRD3, HTR1B, HTR2B |
2.79148 |
|
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC, TOP1 |
2.79148 |
|
[BP] GO:0006811 |
None
|
ABCB1, ADRA1A, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD1, DRD2, DRD3, FABP3, GRIA2, GRIA4, GRIK5, HTR2A, HTR2B, HTR2C, PPARA, PPARD, SLC1A1 |
2.78004 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ADORA2A, ALPL, APP, AXL, BCL2, CBR1, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HIF1A, HMGCR, HTR2B, KDR, KIT, MET, MIF, MMP2, MMP9, PPARD, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
2.77934 |
|
[BP] GO:0001936 |
None
|
F3, HIF1A, HTR2B, KDR, PRKCA, TEK, XDH |
2.77335 |
|
[BP] GO:0019933 |
None
|
ADORA2A, ADRA1A, DRD1, DRD2, DRD3, HTR5A |
2.76885 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, KIT, MMP9, TERT |
2.75773 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA2A, ADORA3, ALOX15, APP, AXL, BCL2, CNR2, DRD1, HTR1A, HTR2C, KIT, MIF, MPO, PIK3CA, PIK3CB, POLB, PTGES, PTGS1, PTGS2, SRC |
2.75109 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.74595 |
|
[BP] GO:0006680 |
None
|
GBA, GBA2 |
2.74595 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.74595 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.74595 |
|
[BP] GO:0070229 |
negative regulation of lymphocyte apoptotic process
|
AURKB, HIF1A, IDO1, MIF |
2.74595 |
|
[BP] GO:0007205 |
None
|
ADORA2A, CHRM1, HTR1B, HTR2B |
2.74595 |
|
[BP] GO:0001667 |
ameboidal-type cell migration
|
CYP1B1, HIF1A, HTR2B, KDR, KIT, PIK3CA, PPARD |
2.74431 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, SRC, TNKS, TOP1 |
2.73868 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, MIF, TERT, TNKS |
2.72938 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD2, DRD3, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, MMP9, PTGS2 |
2.72254 |
|
[BP] GO:1901215 |
negative regulation of neuron death
|
ADORA2A, AXL, BCL2, GBA, HIF1A, PIK3CA, PPARA, TERT |
2.70792 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.70792 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
ADORA2A, APP, CNR1, CNR2, CSNK2A1, DRD2, DRD3, DUSP3, FABP4, GBA, GRM3, HMGCR, IGF1R, MMP9, PRKCA, PTGS2, PTPN1, SRC |
2.69893 |
|
[BP] GO:0035265 |
organ growth
|
ADRA1A, BCL2, CYP19A1, ESR1 |
2.69467 |
|
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.69467 |
|
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.69467 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.69467 |
|
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, EGFR, MPO |
2.69467 |
|
[BP] GO:0007631 |
None
|
ADORA2A, APP, DRD1, DRD2, HTR1B, HTR2C |
2.68371 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
2.68126 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, GBA, HSD11B2, PTGS2 |
2.6736 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PPARD, PTGES, PTGS2, SMAD3, SRC |
2.67062 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.66974 |
|
[BP] GO:0042220 |
None
|
CNR1, DRD2, DRD3, HTR1B |
2.64332 |
|
[BP] GO:0045777 |
None
|
ADORA1, ADRA1A, CNR1, HSD11B2 |
2.64332 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, HTR2A |
2.64332 |
|
[BP] GO:0010039 |
response to iron ion
|
BCL2, CYP1A1, DRD2, HIF1A |
2.64332 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, FLT3, KDR, KIT, PPARD, TEK |
2.63923 |
|
[BP] GO:0019229 |
None
|
ADRA1A, CHRM1, EGFR, HTR2A, PTGS2 |
2.63856 |
|
[BP] GO:0051234 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADRA1A, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CHRM1, DRD1, DRD2, DRD3, EGFR, F10, FABP3, FUCA1, GAA, GRIA2, GRIA4, GRIK5, HIF1A, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KIT, MGAM, MIF, MMP12, MMP9, MPO, PPARA, PPARD, SIGMAR1, SLC1A1, SRC, TERT, TNKS, XDH |
2.63834 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, GRM1, HTR2A, HTR2B, HTR2C |
2.6152 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PPARD, PTGS2, TYR |
2.60949 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.60663 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.60258 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.60258 |
|
[BP] GO:0070989 |
oxidative demethylation
|
CYP1A2, CYP2D6, CYP3A4 |
2.60258 |
|
[BP] GO:0043523 |
regulation of neuron apoptotic process
|
ADORA2A, AXL, BCL2, GRIK5, HIF1A, PIK3CA, SIGMAR1, TERT |
2.59997 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.59997 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.59997 |
|
[BP] GO:0040013 |
None
|
ADORA1, ADORA2A, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF, PPARD |
2.59997 |
|
[BP] GO:0007194 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.59997 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.59997 |
|
[BP] GO:0098801 |
None
|
ADORA1, ADORA2A, DRD2, DRD3 |
2.59997 |
|
[BP] GO:0042596 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.59997 |
|
[BP] GO:0019935 |
None
|
ADORA2A, ADRA1A, DRD1, DRD2, DRD3, HTR5A |
2.57754 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, GRM1, INSR, KIT, PIK3CA, PIK3CB, PTPN1, SRC |
2.55679 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.55679 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.55679 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.55679 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.55679 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.5529 |
|
[BP] GO:0006775 |
fat-soluble vitamin metabolic process
|
CBR1, CYP1A1, CYP3A4, PPARD |
2.5529 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.5529 |
|
[BP] GO:0045907 |
None
|
ADRA1A, EGFR, HTR2A, PTGS2 |
2.5529 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
ADORA2A, BCL2, HIF1A, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.53775 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, MPO |
2.53695 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, HIF1A, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.52804 |
|
[BP] GO:0072330 |
monocarboxylic acid biosynthetic process
|
ALOX15, CYP1A1, IDO1, MIF, PTGES, PTGS1, PTGS2 |
2.52804 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.52804 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PTGS2 |
2.52631 |
|
[BP] GO:0060402 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, HTR2C |
2.52631 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.52631 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.51017 |
|
[BP] GO:0035815 |
None
|
ADORA2A, DRD2, DRD3 |
2.51017 |
|
[BP] GO:1903580 |
None
|
ESRRB, HIF1A, HTR2A, INSR |
2.50944 |
|
[BP] GO:0031280 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.50944 |
|
[BP] GO:0071456 |
cellular response to hypoxia
|
BCL2, HIF1A, PPARD, PTGS2, SRC, TERT |
2.49793 |
|
[BP] GO:0090276 |
None
|
CNR1, DRD2, EGFR, HIF1A, HMGCR, HTR2C, PPARD, PRKCA |
2.49666 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGES, PTGS2, SRC |
2.48191 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PPARD, PTGES, PTGS2, SMAD3, SRC |
2.48068 |
|
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, PTGS2 |
2.47812 |
|
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
FLT3, KDR, KIT, PPARD, TEK |
2.47067 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SRC, TERT |
2.45674 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
ADORA2A, CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.44274 |
|
[BP] GO:0014910 |
regulation of smooth muscle cell migration
|
APEX1, BCL2, PPARD, SRC, TERT |
2.44264 |
|
[BP] GO:0006110 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA |
2.44264 |
|
[BP] GO:0015908 |
None
|
DRD2, DRD3, FABP3, PPARA, PPARD |
2.44264 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF, PPARD |
2.42951 |
|
[BP] GO:0051350 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.42114 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.42114 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.42114 |
|
[BP] GO:0019377 |
None
|
FUCA1, GBA, GBA2 |
2.42114 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
CYP1B1, DRD2, HIF1A, HSPA1A, HTR2B, IDO1, MIF, MMP12, PTGS2, SMAD3, SRC |
2.42016 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
2.41999 |
|
[BP] GO:0051179 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADRA1A, ALOX15, ALOX5, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CHRM1, DRD1, DRD2, DRD3, EGFR, ESR1, F10, FABP3, FUCA1, GAA, GRIA2, GRIA4, GRIK5, HIF1A, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KIT, MGAM, MIF, MMP12, MMP9, MPO, PPARA, PPARD, SIGMAR1, SLC1A1, SRC, TERT, TNKS, TNKS2, XDH |
2.4127 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CYP1B1, F3, HIF1A, KDR, KIT, PRKCA, PTGS2, TEK, TERT, XDH |
2.39656 |
|
[BP] GO:0060079 |
None
|
ADORA1, ADORA2A, GRIA2, GRIA4, GRIK5 |
2.38991 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.38083 |
|
[BP] GO:0031644 |
None
|
ADORA1, GBA, GPR35, GRM1, HTR2C |
2.36268 |
|
[BP] GO:1903524 |
None
|
ADRA1A, EGFR, HTR2A, PTGS2, SLC1A1 |
2.36268 |
|
[BP] GO:0036294 |
cellular response to decreased oxygen levels
|
BCL2, HIF1A, PPARD, PTGS2, SRC, TERT |
2.3613 |
|
[BP] GO:2001251 |
None
|
DNMT1, PHF8, SRC, TNKS, TNKS2, TOP2A |
2.3613 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.35707 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
2.34843 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
2.34843 |
|
[BP] GO:0007566 |
embryo implantation
|
MMP2, MMP9, PPARD, PTGS2 |
2.34843 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.34843 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.34843 |
|
[BP] GO:0009822 |
alkaloid catabolic process
|
CYP2D6, CYP3A4 |
2.34843 |
|
[BP] GO:0000023 |
None
|
GAA, MGAM |
2.34843 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.34843 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.34843 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.34843 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.34843 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.34843 |
|
[BP] GO:0051704 |
multi-organism process
|
APP, AXL, BCL2, CDK6, CHRM2, CYP1A1, DRD3, DYRK1A, EGFR, HSD11B2, HSPA1A, HTR2A, IDO1, INSR, KDR, MET, MMP1, MMP12, MPO, POLA1, SMAD3, SRC, TOP1 |
2.34843 |
|
[BP] GO:0046903 |
None
|
ALOX5, APP, AXL, CA2, CA9, CHRM1, DRD2, DRD3, FUCA1, GAA, HIF1A, HSPA1A, KIT, MGAM, MIF, MMP9, MPO, SLC1A1, XDH |
2.34807 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, TERT |
2.34671 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
HIF1A, KDR, MET, MMP9, PRKCA, PTGS2, SRC, TEK |
2.34437 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
2.32528 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, GBA, HIF1A, IGF1R, INSR, KDR, MET, MMP12, PHF8, PPARA, PPARD, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.32423 |
|
[BP] GO:0007189 |
None
|
ADORA2A, ADRA1A, DRD1, DRD2, DRD3 |
2.32404 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.32404 |
|
[BP] GO:0038128 |
None
|
EGFR, PIK3CA, PRKCA, SRC |
2.31214 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
2.31214 |
|
[BP] GO:1900544 |
None
|
ADORA2A, DRD1, ESRRB, HIF1A, HTR2A, INSR |
2.2987 |
|
[BP] GO:0045981 |
None
|
ADORA2A, DRD1, ESRRB, HIF1A, HTR2A, INSR |
2.2987 |
|
[BP] GO:2000146 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF, PPARD |
2.28399 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
ADORA2A, APP, BCL2, CHRM1, CSNK2A1, DRD1, DRD2, DRD3, EGFR, GRIK5, HIF1A, HMGCR, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.28094 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.27483 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM4 |
2.27483 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.27483 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.27483 |
|
[BP] GO:0048546 |
None
|
BCL2, EGFR, HIF1A |
2.27483 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.27483 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ABCG2, ACHE, ADORA2A, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FLT3, FUCA1, FUT7, GBA, GBA2, GLO1, HIF1A, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PHF8, PIK3CA, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.26734 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, HIF1A, MET, SMAD3, SRC |
2.26734 |
|
[BP] GO:0019637 |
organophosphate metabolic process
|
ACHE, ADORA2A, ALOX15, CSNK2A1, DRD2, EGFR, HMGCR, HSPA1A, HTR2B, HTR2C, KIT, MET, PIK3CA, PIK3CB, PPARD, PTGS2, XDH |
2.25843 |
|
[BP] GO:0043470 |
None
|
ESRRB, HIF1A, HTR2A, INSR, PPARA |
2.25254 |
|
[BP] GO:0006810 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADRA1A, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CHRM1, DRD1, DRD2, DRD3, F10, FABP3, FUCA1, GAA, GRIA2, GRIA4, GRIK5, HIF1A, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KIT, MGAM, MIF, MMP12, MMP9, MPO, PPARA, PPARD, SIGMAR1, SLC1A1, SRC, TNKS, XDH |
2.24306 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.23996 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.23996 |
|
[BP] GO:0050900 |
leukocyte migration
|
CNR2, FUT7, KIT, MIF, MMP1, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.22946 |
|
[BP] GO:0060401 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, HTR2C |
2.22946 |
|
[BP] GO:0045598 |
None
|
HTR2A, HTR2C, PPARD, PTGS2, RORC, SMAD3 |
2.2118 |
|
[BP] GO:0042060 |
None
|
ALOX15, EGFR, PPARA, PPARD, SMAD3 |
2.20504 |
|
[BP] GO:0010631 |
epithelial cell migration
|
CYP1B1, KDR, KIT, PIK3CA, PPARD |
2.20504 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.20194 |
|
[BP] GO:0022898 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9 |
2.19425 |
|
[BP] GO:0090257 |
None
|
ADORA1, ADRA1A, CHRM1, CHRM2, KIT, PRKCA, PTGS2, SMAD3 |
2.19425 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.1895 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
APP, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, HIF1A, HMGCR, IDO1, INSR, KDR, KIT, PIM1, PPARD, PRKCA, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
2.1895 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, DYRK1A, PRKCA, TNKS |
2.18325 |
|
[BP] GO:0043467 |
regulation of generation of precursor metabolites and energy
|
ESRRB, HIF1A, HTR2A, INSR, PIK3CA, PPARA |
2.17905 |
|
[BP] GO:0001961 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.16906 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.16906 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, HIF1A, HTR2A, INSR, PPARA, RORC, SRC |
2.16169 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA2A, ADORA3, APEX1, APP, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GBA, GLO1, GRM3, GRM5, GRM8, HIF1A, HMGCR, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, PHF8, PIM1, POLA1, PPARA, PPARD, PRKCA, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.16039 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, HTR5A, PTGS2 |
2.14361 |
|
[BP] GO:0051000 |
None
|
HIF1A, HTR2B, TERT |
2.13396 |
|
[BP] GO:0043536 |
positive regulation of blood vessel endothelial cell migration
|
HIF1A, KDR, PRKCA, PTGS2 |
2.13396 |
|
[BP] GO:0051271 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF, PPARD |
2.12955 |
|
[BP] GO:0032963 |
collagen metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.11323 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ADORA2A, ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HIF1A, HTR2B, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NUAK1, PHF8, PIK3CA, PIM1, POLB, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.10661 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
ADORA2A, CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.10315 |
|
[BP] GO:0045761 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.10088 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.10088 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, HTR2C |
2.10088 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, HTR2C |
2.10088 |
|
[BP] GO:0071453 |
cellular response to oxygen levels
|
BCL2, HIF1A, PPARD, PTGS2, SRC, TERT |
2.09583 |
|
[BP] GO:0050673 |
epithelial cell proliferation
|
ESR1, KIT, PIK3CB, PPARD, TEK |
2.09583 |
|
[BP] GO:0098908 |
None
|
GBA, GPR35 |
2.09583 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.09583 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.09583 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.09583 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.09583 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.09583 |
|
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.09583 |
|
[BP] GO:0051241 |
negative regulation of multicellular organismal process
|
ADORA1, ADRA1A, APP, AXL, BCL2, CDK6, DRD2, DRD3, EGFR, GBA, GPR35, HIF1A, IDO1, PPARD, PTGS2, SMAD3, TEK, TERT, XDH |
2.08631 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.078 |
|
[BP] GO:0035162 |
embryonic hemopoiesis
|
HIF1A, KDR, KIT |
2.078 |
|
[BP] GO:0090342 |
None
|
CDK6, MIF, NUAK1, TERT |
2.07513 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, HTR2B |
2.05595 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.05595 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PTGS2, SMAD3, SRC, TERT |
2.05373 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, GBA, HIF1A, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PTPN1 |
2.04733 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.04731 |
|
[BP] GO:0032409 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9 |
2.04731 |
|
[BP] GO:0060760 |
None
|
AXL, HIF1A, HSPA1A, MMP12 |
2.04314 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.03853 |
|
[BP] GO:0030258 |
lipid modification
|
CYP1A1, CYP3A4, EGFR, KIT, MET, PIK3CA, PIK3CB, PPARD |
2.03692 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, DYRK1A, PRKCA, TNKS |
2.03685 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ADORA2A, ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUT7, HIF1A, HTR2B, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PHF8, PIK3CA, PIM1, POLB, PPARA, PPARD, PRKCA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.02025 |
|
[BP] GO:0035588 |
None
|
ADORA1, ADORA2A, ADORA3 |
2.02025 |
|
[BP] GO:0001892 |
None
|
EGFR, ESRRB, HIF1A |
2.02025 |
|
[BP] GO:0035249 |
None
|
ADORA2A, GRIA2, GRIK5 |
2.02025 |
|
[BP] GO:0035809 |
None
|
ADORA2A, AKR1B1, DRD2 |
2.02025 |
|
[BP] GO:0006633 |
None
|
ALOX15, MIF, PTGES, PTGS1, PTGS2 |
2.01853 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
HIF1A, MMP1, MMP12, MMP2, MMP9 |
2.01853 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA2A, ADORA3, ADRA1A, APP, AXL, BACE1, CA4, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, F10, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC1A1, TEK |
12.7868 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ABCG2, ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, APP, AXL, BACE1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, F10, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MGAM, PTGS2, SIGMAR1, SLC1A1, SRC, TEK |
11.7043 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA2A, ADORA3, ADRA1A, APP, AXL, BACE1, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC1A1, TEK |
11.4067 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, ALOX5, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MMP2, PHF8, PIK3CA, PIK3CB, PIM1, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TYR |
10.499 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, ALPL, APP, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, GAA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MGAM, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PTPN1, SLC1A1, SMAD3, SRC, TEK, TERT |
10.4985 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ABCG2, ADORA1, ADORA2A, ADRA1A, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, INSR, MET, MGAM, PTGS2, SIGMAR1, SLC1A1, SRC, TEK |
9.52303 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, ALOX15, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC1A1, SRC, TBXAS1, TEK, TYR |
8.11131 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, ADORA2A, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, SRC, TEK |
5.06816 |
|
[CC] GO:0120025 |
None
|
ADORA1, ADORA2A, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CNR1, CNR2, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PTGS2, SRC, TEK |
5.02253 |
|
[CC] GO:0043005 |
None
|
ADORA1, ADORA2A, APP, BACE1, CA2, CHRM1, CHRM2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, PTGS2, SRC |
4.85252 |
|
[CC] GO:0031224 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, ALPL, APP, AXL, BACE1, CA12, CA14, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, PTGES, SIGMAR1, SLC1A1, TBXAS1, TEK, TYR |
4.68101 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, F10, FLT3, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1, TBXAS1 |
4.63384 |
|
[CC] GO:0097458 |
None
|
ADORA1, ADORA2A, APP, BACE1, CA2, CHRM1, CHRM2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HIF1A, HTR2A, HTR2B, HTR5A, IDO1, INSR, PTGS1, PTGS2, SIGMAR1, SRC, TOP1 |
4.49318 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGES, PTGS1, PTGS2, SIGMAR1, TBXAS1 |
4.46009 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
4.3946 |
|
[CC] GO:0097060 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, SIGMAR1 |
4.24302 |
|
[CC] GO:0014069 |
None
|
ADORA1, ADORA2A, CHRM1, DRD2, GRIK5, GRM1, GRM3, GRM5, SIGMAR1, SRC |
4.07079 |
|
[CC] GO:0099572 |
None
|
ADORA1, ADORA2A, CHRM1, DRD2, GRIK5, GRM1, GRM3, GRM5, SIGMAR1, SRC |
4.07079 |
|
[CC] GO:0016021 |
None
|
ABCB1, ABCG2, ADORA1, ADORA2A, ADORA3, ADRA1A, ALPL, APP, AXL, BACE1, CA12, CA14, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, PTGES, SIGMAR1, SLC1A1, TBXAS1, TEK, TYR |
3.98134 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, ADORA2A, APP, CHRM1, CHRM2, CHRM4, CNR1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, SIGMAR1, SRC |
3.93955 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA6, CA9, CBR1, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR4, HTR5A, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MGAM, MIF, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
3.91258 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA7, CBR1, CDC25B, CDK6, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GRIA2, GRIA4, GRIK5, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR4, HTR5A, IDO1, INSR, KDR, KIT, MAOA, MGAM, MIF, MMP2, MMP9, MPO, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
3.82238 |
|
[CC] GO:0042734 |
None
|
CNR1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
3.61112 |
|
[CC] GO:0031090 |
None
|
ABCG2, ADRA1A, ALOX5, APP, BACE1, BCL2, CA4, CHRM2, CNR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DRD1, DRD2, EGFR, FUT7, GAA, GBA, GBA2, GRIA2, GRIA4, HMGCR, INSR, MAOA, MGAM, PHF8, PRKCA, PTGS1, PTGS2, SIGMAR1, SMAD3, SRC, TNKS, TNKS2, TYR |
3.60399 |
|
[CC] GO:0045121 |
membrane raft
|
ADRA1A, APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
3.44543 |
|
[CC] GO:0098857 |
membrane microdomain
|
ADRA1A, APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
3.42028 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ABCG2, ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA6, CBR1, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM5, HIF1A, HMGCR, HSPA1A, HTR2A, HTR4, HTR5A, IGF1R, INSR, KDR, KIT, MAOA, MGAM, MIF, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
3.36782 |
|
[CC] GO:0044463 |
None
|
ADORA1, ADORA2A, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CNR1, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM3, HIF1A, HTR2A, INSR, PTGS1, SIGMAR1, SRC |
3.1251 |
|
[CC] GO:0120038 |
None
|
ADORA1, ADORA2A, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CNR1, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM3, HIF1A, HTR2A, INSR, PTGS1, SIGMAR1, SRC |
3.1251 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.1055 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, GRIK5, HMGCR, HSPA1A, HTR5A, KDR, PRKCA, PTGS2, PTPN1, SIGMAR1, XDH |
2.83869 |
|
[CC] GO:0098589 |
membrane region
|
ADRA1A, APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.77682 |
|
[CC] GO:0009330 |
None
|
TOP1, TOP2A |
2.74595 |
|
[CC] GO:0043235 |
receptor complex
|
ABCG2, APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
2.48191 |
|
[CC] GO:0045211 |
None
|
CHRM1, CHRM2, CHRM4, GRIA2, GRIA4, GRIK5, GRM3, SIGMAR1 |
2.38155 |
|
[CC] GO:0099056 |
None
|
ADORA1, ADORA2A |
2.34843 |
|
[CC] GO:0098889 |
None
|
ADORA1, ADORA2A |
2.34843 |
|
[CC] GO:0005901 |
caveola
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.34843 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.24695 |
|
[CC] GO:0044422 |
organelle part
|
ABCG2, ADORA2A, ADRA1A, AKR1B1, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA4, CA9, CDC25B, CDK6, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GRIA2, GRIA4, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSPA1A, IDO1, INSR, MAOA, MGAM, MIF, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR |
2.22946 |
|
[CC] GO:0044309 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.2118 |
|
[CC] GO:0044446 |
intracellular organelle part
|
ABCG2, ADORA2A, ADRA1A, AKR1B1, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA4, CA9, CDC25B, CDK6, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GRIA2, GRIA4, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSPA1A, INSR, MAOA, MGAM, MIF, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR |
2.10839 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.02025 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM4, DRD1, DRD2, DRD3, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
21.4456 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PPARD, RORC, SIGMAR1, TEK |
18.7276 |
|
[MF] GO:0008227 |
None
|
ADRA1A, CHRM1, CHRM2, CHRM4, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
17.563 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
17.0271 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AXL, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PPARD, RORC, SIGMAR1, TEK |
16.9941 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PPARD, RORC, SIGMAR1, TEK |
16.8645 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ABCG2, ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
16.8645 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PHF8, PIM1, PPARA, PPARD, PRKCA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
16.6031 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PPARD, RORC, SIGMAR1, SMAD3, TEK |
15.9807 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, SIGMAR1, TEK |
15.0614 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA2A, ADORA3, ADRA1A, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, SIGMAR1, TEK |
15.0614 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
14.83 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.8004 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.8004 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5947 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5947 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MAOA, MPO, NQO2, PHF8, PTGS1, PTGS2, TBXAS1, TYR, XDH |
12.5766 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ABCG2, ACHE, AURKB, AXL, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DYRK1A, EGFR, FLT3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, SIGMAR1, SRC, TEK, TOP1, TOP2A |
12.4712 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
11.8155 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DRD3, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, KIT, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
11.7452 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
11.0471 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, IDO1, MPO, PTGS1, PTGS2, SRC, TBXAS1 |
10.0757 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA2A, ADORA3, ADRA1A, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DRD3, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, SIGMAR1 |
10.0211 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, HMGCR, HSD11B2, HSD17B1, IDO1, MPO, NQO2, POLA1, PTGES, PTGS1, PTGS2, SRC, TBXAS1, XDH |
9.98216 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, IDO1, MPO, PTGS1, PTGS2, SRC, TBXAS1 |
9.65576 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
9.24669 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
8.87739 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PHF8, TBXAS1, XDH |
8.84578 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PHF8, PTGS1, PTGS2, TBXAS1, TYR |
7.93039 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA6, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PHF8, PPARA, PPARD, PRKCA, PTPN1, RORC, SMAD3, TNKS |
7.85148 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, POLB |
7.73454 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
7.62385 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.17894 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.10873 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, TBXAS1, TYR |
6.78339 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
6.30699 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
6.30157 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, IDO1, KIT, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
5.97012 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
5.60509 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ABCG2, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HIF1A, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MMP12, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP1, TOP2A, XDH |
5.58763 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.41371 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
5.36722 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
5.36722 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, SRC, TEK |
5.25838 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, GLO1, POLB |
5.19021 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
5.00963 |
|
[MF] GO:0005496 |
steroid binding
|
CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
4.89785 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, SRC, TEK, TOP1 |
4.86706 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
4.85392 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ABCG2, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HIF1A, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MMP12, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP1, TOP2A, XDH |
4.75716 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR, KIT |
4.68919 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, SRC, TEK, TERT, TOP1 |
4.36191 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, SRC, TEK, TOP1 |
4.36191 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB |
4.33124 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA2A, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DAO, DNMT1, DRD1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUCA1, FUT7, GAA, GBA, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HIF1A, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MGAM, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PHF8, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
4.25656 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ABCG2, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARD, PRKCA, SLC1A1, SRC, TEK, TOP1, TOP2A, XDH |
4.01858 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.94613 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, SRC, TEK, TOP1 |
3.83862 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM4 |
3.75612 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ABCG2, ALOX15, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, DAO, DYRK1A, EGFR, F10, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARD, PRKCA, PTGES, SLC1A1, SRC, TEK, TOP1, TOP2A, XDH |
3.58836 |
|
[MF] GO:0019899 |
enzyme binding
|
ADORA2A, APP, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, HIF1A, HMGCR, HSPA1A, KIT, MET, MIF, POLA1, POLB, PPARA, PRKCA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.42135 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, SRC, TEK, TOP1, TOP2A, XDH |
3.33014 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DAO, DNMT1, DYRK1A, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, SRC, TEK, TOP1, TOP2A, XDH |
3.32833 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
3.28827 |
|
[MF] GO:0001609 |
None
|
ADORA1, ADORA2A, ADORA3 |
3.28827 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, ADORA2A, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, KIT, MET, MIF, MMP9, NQO2, PTGS2, SMAD3, TERT, TOP2A, TYR, XDH |
3.20828 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, PPARD, RORC |
3.0001 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ABCG2, ACHE, ADORA1, ADORA2A, ADRA1A, AOX1, AXL, BCL2, DAO, DRD2, EGFR, FLT3, HIF1A, HMGCR, KIT, NQO2, PPARD, PTGS2, SMAD3, TERT, TOP2A, TYR, XDH |
2.99207 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
2.95273 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, NQO2 |
2.91267 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
2.9095 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.84985 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
2.84985 |
|
[MF] GO:0051213 |
dioxygenase activity
|
ALOX15, ALOX5, IDO1, PHF8, PTGS1, PTGS2 |
2.79148 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.74595 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.74595 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.74595 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.74595 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.74595 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.74595 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3 |
2.60258 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3 |
2.51017 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.47067 |
|
[MF] GO:0015926 |
None
|
GAA, GBA2, MGAM |
2.42114 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A |
2.40888 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.38991 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.34843 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.34843 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.34843 |
|
[MF] GO:0032450 |
None
|
GAA, MGAM |
2.34843 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.34843 |
|
[MF] GO:0004348 |
None
|
GBA, GBA2 |
2.34843 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.31001 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A |
2.30949 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.29828 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, SRC, TEK, TOP1, TOP2A |
2.27546 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.27483 |
|
[MF] GO:0046982 |
protein heterodimerization activity
|
ADORA1, ADORA2A, ADRA1A, AXL, BCL2, DRD2, EGFR, HIF1A, PPARD, SMAD3, TOP2A, TYR |
2.1974 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.19675 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM4 |
2.13396 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.13396 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.09583 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.09583 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.09583 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.09583 |
|
[MF] GO:0004558 |
None
|
GAA, MGAM |
2.09583 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.09583 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.078 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.078 |
|
[MF] GO:0016798 |
None
|
APEX1, FUCA1, GAA, GBA, GBA2, MGAM |
2.05373 |
|
[MF] GO:1901338 |
None
|
DRD1, DRD2, DRD3 |
2.02025 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.02025 |
