Prescription Description
| Prescription ID | TCMF3371 |
| Pinyin Name | Fu Fang Zhi Jin Gan Chong Ji |
| Chinese Name | 复方制金柑冲剂 |
| English Name | Fu Fang Zhi Jin Gan Infusion |
| Function Description | 胃脘痛, 腹胀 |
| Indications | Stomach ache disorder |
| Disease ICD-11 Category |
SA51 [Stomach ache disorder (TM1), 胃脘痛 (TM1)
]; |
| Human Tissues Associated with Indication | Intestine, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1097 | Fortunella japonica | 金柑 | TCMH1097 | AB456110 |
| TCMH486 | Syzygium aromaticum | 丁香 | TCMH486 | GBVI185-11 |
| TCMH1742 | Cinnamomum cassia | 肉桂 | TCMH1742 | GQ255631 |
| TCMH1803 | Amomum villosum | 砂仁 | TCMH1803 | ITSAD521-14 |
| TCMH512 | Fructus amomi rotundus | 豆蔻 | TCMH512 | |
| TCMH1533 | Saussurea lappa | 木香 | TCMH1533 | |
| TCMH249 | Aquilaria agallocha | 沉香 | TCMH249 | KU879012 |
| TCMH1466 | Rosa rugosa | 玫瑰花 | TCMH1466 | ITSAJ4480-14 |
| TCMH2376 | Corydalis yanhusuo | 延胡索 | TCMH2376 | |
| TCMH1469 | Flos mume | 梅花 | TCMH1469 | |
| TCMH2265 | Cyperus rotundus | 香附 | TCMH2265 | GENG1049-15 |
| TCMH2281 | Citrus medica | 香橼 | TCMH2281 | ITSAJ4663-14 |
| TCMH407 | Salvia miltiorrhiza | 丹参 | TCMH407 | ITSAH2408-14 |
| TCMH1080 | Platycodon grandiflorum | 桔梗 | TCMH1080 | ITSAJ4293-14 |
| TCMH890 | Cortex magnoliae officinalis | 厚朴 | TCMH890 | ITSAM1591-14 |
| TCMH672 | Alpinia officinarum | 高良姜 | TCMH672 | ITSAK2176-14 |
| TCMH1059 | Glycine max | 姜 | TCMH1059 | ITSAJ4675-14 |
| TCMH2618 | Citrus aurantium | 枳壳 | TCMH2618 | ITSAA1279-14 |
| TCMH619 | Citrus medica var. sarcodactylis | 佛手 | TCMH619 | ITSAJ4647-14 |
| TCMH160 | Piper cubeba | 毕澄茄 | TCMH160 | MH493317 |
| TCMH243 | Pericarpium citri reticulatae | 陈皮 | TCMH243 | |
| TCMH1695 | Pericarpium citri reticulatae viride | 青皮 | TCMH1695 | |
| TCMH728 | Pogostemon cablin | 广藿香 | TCMH728 | ITSAJ4146-14 |
| TCMH2216 | Evodia rutaecarpa | 吴茱萸 | TCMH2216 | |
| TCMH2532 | Curcuma aromatica | 郁金 | TCMH2532 | ITSAF2298-14 |
| TCMH2721 | Perilla frutescens var. arguta | 紫苏梗 | TCMH2721 | ITSAF2620-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
Showing 1 to 10 of 167 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1168 | Trichomonas vaginalis |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1183 | Candida albicans SC5314 |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1187 | Enterococcus faecalis ATCC 29212 |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1201 | Staphylococcus epidermidis ATCC 12228 |
Showing 1 to 10 of 88 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, RELA, SRC | 4.25967 |
| [BP] GO:0000904 | cell morphogenesis involved in differentiation | AR, AXL, MET, SRC, TEK | 2.05049 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGES, RELA, SLC6A4, SRC | 3.0635 |
| [BP] GO:0001503 | ossification | ALPL, BCL2, EGFR, MMP2, MMP9, TEK | 2.67005 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, HTR1A, INSR, MAOA, SLC6A2, SLC6A4, SMAD3 | 5.52766 |
| [BP] GO:0001659 | None | ADORA1, DRD1, DRD2, HTR2A | 2.86493 |
| [BP] GO:0001662 | None | BCL2, DRD1, HTR1A, HTR2C | 2.91346 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, DRD2, MMP2, PPARA, SLC6A4, SMAD3, SRC, TEK, TERT | 4.61138 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGES, TBXAS1 | 3.93029 |
| [BP] GO:0001817 | regulation of cytokine production | ADRA2A, AXL, CYP1B1, DRD2, F2, HSPA1A, HTR2B, MAP3K7, MIF, MMP12, RELA, SMAD3, SRC | 2.63341 |
Showing 1 to 10 of 711 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCG2 | 0.5699 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | MAP2K1, FLT3, PIM1, RELA | 2.8204 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, SMAD3, CSNK2A1, SRC, INSR, MAP3K7, MET, EGFR, IGF1R | 7.9382 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA, RELA | 1.0225 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2, CACNA1C, ADRA1A | 1.0596 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | SMAD3, MMP2, BCL2, PIM1, F3, RELA | 3.7469 |
| Alcoholism_Homo sapiens_hsa05034 | MAP2K1, MAOA, DRD1, DRD2 | 1.4041 |
| Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | CACNA1C | 0.3904 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | INSR | 0.6078 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP, CACNA1C | 0.5397 |
Showing 1 to 10 of 187 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples