GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
17.1934 |
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
17.1934 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA12, CA2, CA7, CHRM1, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, ESR1, FABP3, FABP4, FLT3, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, KDR, MET, PIK3CA, PIK3CB, POLA1, POLB, PTGS1, PTGS2, SRC, TNKS, TNKS2, XDH |
12.0326 |
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, ESR1, FABP3, FLT3, HSD11B2, HSD17B2, HTR1B, HTR5A, PTGS2, RORC, SRC, TYR |
9.93358 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALOX15, ALPL, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, KDR, MMP2, MMP9, PIK3CA, POLB, PTGS2, RORC, SRC, TYR |
9.81923 |
[BP] GO:0007187 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, CNR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
9.81193 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, AXL, BCL2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, HSD11B2, HSD17B2, HTR1B, HTR5A, IGF1R, MMP2, MMP9, PIK3CA, POLB, PTGS2, RORC, SRC, TYR |
9.65173 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HTR1B, HTR5A, IGF1R, KDR, MMP2, PIK3CA, POLB, PTGS2, RORC, SRC, TYR |
8.46858 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FUT7, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PIK3CA, PIK3CB, PTGS1, PTGS2, TBXAS1 |
8.46858 |
[BP] GO:0007193 |
None
|
CHRM1, CHRM2, CHRM4, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
8.0757 |
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FLT3, HSD11B2, HTR1B, HTR5A, PTGS2, RORC, SRC, TYR |
7.1295 |
[BP] GO:0097756 |
None
|
HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
7.1295 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, BCL2, CA9, CNR1, CNR2, CYP1A1, CYP1B1, FABP3, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KDR, POLB, PTGS2, SRC |
7.07742 |
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.91498 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.79134 |
[BP] GO:0007188 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
6.74031 |
[BP] GO:0032501 |
multicellular organismal process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AXL, BCL2, CHRM1, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, ESR1, FABP4, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IGF1R, MET, MMP1, MMP2, MMP9, PIK3CA, PIM1, PTGS2, RORC, SRC, TNKS2, TYR |
6.67478 |
[BP] GO:0010647 |
positive regulation of cell communication
|
AKR1B1, ALOX15, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, HTR2A, HTR2B, HTR2C, HTR6, KDR, MET, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
6.67478 |
[BP] GO:0023056 |
positive regulation of signaling
|
AKR1B1, ALOX15, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, HTR2A, HTR2B, HTR2C, HTR6, KDR, MET, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
6.67174 |
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA3, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, ESR1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, PIK3CA, PIK3CB, SRC |
6.46542 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, TYR |
6.44141 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FUT7, HTR2B, HTR2C, PIK3CA, PIM1, PTGS1, PTGS2, TBXAS1, TYR, XDH |
6.38039 |
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
6.37047 |
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
6.37047 |
[BP] GO:0042310 |
None
|
HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
6.36923 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, TBXAS1 |
6.31056 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
6.21821 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
6.18536 |
[BP] GO:0032844 |
regulation of homeostatic process
|
AURKB, BCL2, CA2, CA7, CNR1, HTR2A, HTR2B, HTR2C, KDR, PIK3CB, PTGS2, SRC, TNKS, TNKS2 |
6.17302 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA3, AKR1B1, ALOX15, ALPL, AURKB, AXL, BCL2, CA2, CA9, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, KDR, MMP2, MMP9, PIK3CA, PIK3CB, POLA1, POLB, PTGS1, PTGS2, PTPN1, RORC, SRC, TYR |
6.16373 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, HTR1B, HTR1D, KDR, POLB, SRC |
6.05866 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, TBXAS1 |
6.0169 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
5.99826 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.88282 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, HTR2C |
5.84952 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, TBXAS1 |
5.82591 |
[BP] GO:0003018 |
None
|
CHRM1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SRC |
5.74892 |
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM4, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
5.53672 |
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM4, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
5.53672 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA3, AKR1B1, BCL2, CDC25B, CHRM1, CSNK2A1, CYP1B1, ESR1, FABP3, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, KDR, MMP2, MMP9, PIM1, PTGS1, PTGS2, SRC, XDH |
5.51797 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
AKR1B1, ALOX15, AXL, BCL2, CYP1B1, FLT3, HTR2A, HTR2B, HTR2C, HTR6, KDR, MET, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
5.49513 |
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC |
5.47031 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PIK3CA, PIK3CB, PTGS1, PTGS2 |
5.45877 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, MMP9, PTGS2, SRC |
5.45288 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CHRM1, CHRM4, CYP1A1, ESR1, FLT3, HTR1A, MET, PIK3CB, PIM1, POLA1, SRC, TYR |
5.44531 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
AKR1B1, ALOX15, AXL, BCL2, CSNK2A1, CYP1B1, FLT3, HTR2A, HTR2B, HTR2C, HTR6, KDR, MET, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
5.44072 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, BCL2, CA2, CA9, CSNK2A1, CYP1A2, ESR1, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, PTGS2, SRC |
5.41666 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CHRM1, CSNK2A1, ESR1, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, KDR, MMP2, MMP9, PIM1, PTGS2 |
5.36292 |
[BP] GO:0032502 |
developmental process
|
ACHE, AKR1B1, ALOX15, ALPL, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP4, FLT3, FUT7, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, POLB, PTGS2, RORC, SRC, TNKS2, TYR |
5.36292 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
5.35304 |
[BP] GO:0097746 |
None
|
CHRM1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.32947 |
[BP] GO:0035296 |
None
|
CHRM1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.32947 |
[BP] GO:0007165 |
signal transduction
|
ADORA3, AKR1B1, AXL, BCL2, CA1, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP1B1, ESR1, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, POLB, PTPN1, RORC, SRC, TNKS, TNKS2 |
5.29828 |
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
5.2678 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
5.25197 |
[BP] GO:0050880 |
None
|
CHRM1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.15216 |
[BP] GO:0035150 |
None
|
CHRM1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.13139 |
[BP] GO:0007200 |
None
|
CHRM1, CHRM2, CHRM4, ESR1, HTR2A, HTR2B, HTR2C |
5.12523 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, MET, PIK3CA, PIK3CB, PTGS1, PTGS2, TBXAS1 |
4.89021 |
[BP] GO:0042592 |
homeostatic process
|
AKR1B1, AXL, BCL2, CA12, CA2, CA7, CNR1, ESR1, FABP3, FABP4, FLT3, HTR2A, HTR2B, HTR2C, MET, PIK3CA, PIK3CB, POLA1, POLB, SRC |
4.87134 |
[BP] GO:0003013 |
None
|
CHRM1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SRC |
4.85394 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, ESR1, FABP3, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, KDR, MET, MMP1, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, RORC, SRC, TNKS, TNKS2, XDH |
4.83847 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
AKR1B1, ALOX15, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, ESR1, FLT3, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
4.8039 |
[BP] GO:0043067 |
regulation of programmed cell death
|
AKR1B1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, ESR1, FLT3, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, XDH |
4.79948 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, BCL2, CA2, CA9, CSNK2A1, CYP1A2, ESR1, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, IGF1R, MMP2, PTGS2, SRC |
4.79549 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, TBXAS1 |
4.74536 |
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
4.7039 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.69697 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
AKR1B1, ALOX15, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, FABP4, FLT3, HTR2A, HTR2B, HTR2C, HTR6, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
4.68568 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, TBXAS1 |
4.68568 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
CA2, CA7, CNR1, CNR2, HTR1B |
4.65234 |
[BP] GO:0050795 |
None
|
CNR1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
4.5914 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
4.55622 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.425 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP4, FLT3, HTR1B, IGF1R, KDR, MMP2, MMP9, PIK3CA, PTGS2, RORC, SRC |
4.32691 |
[BP] GO:0010941 |
regulation of cell death
|
AKR1B1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, ESR1, FLT3, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, XDH |
4.30906 |
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC |
4.30594 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, AURKB, AXL, BCL2, CDC25B, CSNK2A1, FLT3, HTR2B, HTR2C, IGF1R, KDR, MET, PIK3CA, PIK3CB, PIM1, POLB, PTGS2, PTPN1, SRC, TNKS, XDH |
4.285 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, AXL, BCL2, CYP1A1, CYP1B1, ESR1, FABP4, FLT3, HTR1B, IGF1R, KDR, MMP2, PIK3CA, PTGS2, RORC, SRC |
4.26819 |
[BP] GO:0008152 |
metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FLT3, FUT7, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, KDR, MET, MMP1, MMP2, MMP9, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, RORC, SRC, TBXAS1, TNKS, TNKS2, TYR, XDH |
4.26045 |
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.26045 |
[BP] GO:0042981 |
regulation of apoptotic process
|
AKR1B1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, ESR1, FLT3, HTR2B, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, XDH |
4.26018 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, PTGS2, SRC |
4.20718 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FLT3, FUT7, HSD17B1, HSD17B2, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, KDR, MET, MMP1, MMP2, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, RORC, SRC, TBXAS1, TNKS, TNKS2, TYR, XDH |
4.08024 |
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM4 |
4.08024 |
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
4.08024 |
[BP] GO:0007154 |
None
|
AXL, BCL2, CHRM1, CHRM2, CHRM4, CNR1, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PTGS2 |
4.06873 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
AKR1B1, AURKB, AXL, BCL2, CSNK2A1, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SRC |
4.06873 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, ESR1, FABP3, FABP4, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, KDR, MET, MMP1, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, RORC, SRC, TNKS, TNKS2, XDH |
4.00679 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, AURKB, AXL, BCL2, CDC25B, CSNK2A1, FLT3, HTR2B, HTR2C, IGF1R, KDR, MET, PIK3CA, PIK3CB, PIM1, POLB, PTGS2, PTPN1, SRC, TNKS, XDH |
3.98005 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
CNR1, CYP1A1, FABP3, FLT3, HTR2A, HTR2B, HTR2C, PTGS2, RORC, SRC |
3.8677 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
BCL2, CA2, CA7, HTR2A, HTR2B, HTR2C, KDR, SRC |
3.80751 |
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM4 |
3.80751 |
[BP] GO:0032845 |
None
|
BCL2, HTR2A, HTR2B, HTR2C, SRC, TNKS, TNKS2 |
3.79448 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP4, FLT3, HTR1B, IGF1R, KDR, MMP2, MMP9, PIK3CA, POLA1, POLB, PTGS2, PTPN1, RORC, SRC |
3.79448 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, ESR1, FLT3, HSD11B1, HSD17B2, KDR, PIK3CA, POLB, SRC, TYR |
3.78051 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, PTGS1, PTGS2, TBXAS1 |
3.67566 |
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, FLT3, HSD11B2, HTR1B, PTGS2, SRC |
3.66388 |
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, BCL2, CA12, CA2, CA7, CNR1, ESR1, FABP3, FABP4, HTR2A, HTR2B, HTR2C, MET, PIK3CA, PIK3CB |
3.66124 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ALOX15, BCL2, CDC25B, FLT3, HTR2A, HTR2B, HTR2C, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
3.65291 |
[BP] GO:0060548 |
negative regulation of cell death
|
AKR1B1, AURKB, AXL, BCL2, CSNK2A1, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SRC |
3.62759 |
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, FLT3, HSD11B2, HTR1B, PTGS2, SRC |
3.61155 |
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.60641 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.59997 |
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, PIK3CB, PTGS2, TNKS, TNKS2 |
3.58596 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ALOX15, BCL2, CDC25B, FABP3, FLT3, HTR2A, HTR2B, HTR2C, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
3.55278 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ALOX15, BCL2, CDC25B, FABP3, FLT3, HTR2A, HTR2B, HTR2C, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
3.55278 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC |
3.55131 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
AKR1B1, AURKB, AXL, BCL2, CSNK2A1, HTR2B, IGF1R, KDR, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SRC |
3.4716 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ALOX15, BCL2, CDC25B, FLT3, HTR2A, HTR2B, HTR2C, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
3.44719 |
[BP] GO:0007267 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
3.4121 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ALOX15, BCL2, CDC25B, FABP3, FABP4, FLT3, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
3.40416 |
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.38835 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ALOX15, BCL2, CDC25B, FABP3, FABP4, FLT3, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
3.35857 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA3, ALOX15, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1B1, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MET, MMP9, PIK3CB, PTGS2, PTPN1, SRC |
3.30325 |
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, CNR2, HTR1B, HTR2A, PTGS2 |
3.30325 |
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PTGS2 |
3.30325 |
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.30325 |
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, NQO2, PTGS1, RORC |
3.29075 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, ESR1, FABP4, IGF1R, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, TNKS |
3.279 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.13868 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, AKR1B1, ALOX15, ALPL, AXL, BCL2, CA2, CHRM1, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FLT3, HSD11B1, HSD17B2, HTR5A, KDR, MMP9, PIK3CA, PIM1, POLB, PTGS2, RORC, SRC, TYR |
3.08963 |
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
3.0661 |
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CSNK2A1, FLT3, HTR2B, IGF1R, KDR, MET, PIK3CA, PIM1, SRC, TNKS |
3.0661 |
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.05742 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, IGF1R, KDR, PIM1, SRC |
3.02173 |
[BP] GO:0019371 |
None
|
PTGS1, PTGS2, TBXAS1 |
3.02173 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ALOX15, BCL2, CDC25B, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
3.01643 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGS2, SRC |
3.01643 |
[BP] GO:0090066 |
None
|
ALOX15, CHRM1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
3.0086 |
[BP] GO:0023052 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7 |
2.99858 |
[BP] GO:0003008 |
None
|
AKR1B1, BCL2, CHRM1, CNR1, CNR2, CYP1B1, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, PTGS2, SRC, TYR |
2.99542 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, HTR1B, MMP2, MMP9, PTGS2 |
2.97893 |
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, PTGS1, PTGS2 |
2.92026 |
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGS2, SRC |
2.82383 |
[BP] GO:0043271 |
negative regulation of ion transport
|
BCL2, CNR1, HTR1B, HTR2A, MMP9, PTGS2 |
2.81853 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.81853 |
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.81853 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, CA2, CA7, CNR1, CNR2, HTR1B, HTR2A, PTGS2 |
2.78964 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, CA2, CA7, CNR1, CNR2, HTR1B, HTR2A, PTGS2 |
2.78964 |
[BP] GO:0009628 |
response to abiotic stimulus
|
AKR1B1, AURKB, BCL2, CA2, CYP1A1, HSD11B2, HTR1B, HTR2A, HTR2B, MMP2, POLB, PTGS2, SRC, TYR |
2.78198 |
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CSNK2A1, FLT3, HTR2B, IGF1R, KDR, MET, PIK3CA, PIK3CB, PIM1, SRC, TNKS |
2.75082 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ALOX15, FLT3, HTR2A, HTR2B, HTR2C, KDR, PIK3CB, PTPN1, SRC, XDH |
2.73156 |
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.73051 |
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.71885 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA3, BCL2, CHRM1, CHRM4, CYP19A1, CYP1B1, HTR1D, IGF1R, KDR, MET, MMP9, PTGS2, SRC |
2.67199 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, CNR1, CNR2, FABP3, FLT3, HSD11B2, HTR1B, IGF1R, MMP2, PTGS2, SRC, TYR |
2.67006 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, BCL2, CYP19A1, CYP1A1, CYP1B1, HTR1A, TYR |
2.66337 |
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA3, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FLT3, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, MMP1, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, RORC, SRC, TNKS, TNKS2, XDH |
2.66337 |
[BP] GO:0010038 |
response to metal ion
|
ALOX15, BCL2, CA2, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.63022 |
[BP] GO:0007568 |
aging
|
AURKB, BCL2, CNR1, CYP1A1, HTR2A, POLB, PTGS2 |
2.62586 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ALOX15, BCL2, CDC25B, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
2.59015 |
[BP] GO:0048583 |
regulation of response to stimulus
|
AKR1B1, ALOX15, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, FABP4, FLT3, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
2.58318 |
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.57553 |
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM4 |
2.57553 |
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.57553 |
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.57553 |
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, MMP9, PTGS2, PTPN1, SRC |
2.57225 |
[BP] GO:0031401 |
positive regulation of protein modification process
|
ALOX15, BCL2, CDC25B, FLT3, HTR2A, HTR2B, HTR2C, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
2.54823 |
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, HSD11B2, PTGS2, SRC, TYR |
2.54341 |
[BP] GO:0006939 |
None
|
HTR1D, HTR2A, HTR2B, HTR7 |
2.53482 |
[BP] GO:0051049 |
regulation of transport
|
ACHE, ALOX15, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CYP19A1, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP9, PIK3CB, PTGS2, PTPN1, SRC |
2.53482 |
[BP] GO:0006954 |
inflammatory response
|
ADORA3, ALOX15, AXL, CNR2, PIK3CA, PIK3CB, POLB, PTGS1, PTGS2 |
2.52595 |
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.50653 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC |
2.481 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA3, AKR1B1, ALOX15, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, HSD11B2, HTR1A, HTR2C, MMP2, MMP9, PIK3CA, PIK3CB, POLA1, POLB, PTGS1, PTGS2, PTPN1, SRC |
2.44726 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AXL, BCL2, CYP1B1, MMP9, PTGS1, PTGS2, SRC |
2.44272 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.41359 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
2.40844 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, CNR1, CNR2, FABP3, FLT3, HSD11B2, HTR1B, IGF1R, MMP2, PTGS2, SRC, TYR |
2.39741 |
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.38823 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, CYP1A1, CYP1B1, ESR1, FLT3, PTGS2, RORC, SRC |
2.38799 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, BCL2, CYP1B1, MMP9, SRC |
2.38799 |
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.38016 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, BCL2, CYP1B1, SRC |
2.347 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, SRC |
2.347 |
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, FUT7, HTR2B, HTR6, KDR, MMP1, MMP9, PIK3CA, PIK3CB, SRC |
2.34153 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA3, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, ESR1, FABP4, FLT3, HTR2A, HTR2B, IGF1R, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, XDH |
2.31379 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ALOX15, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, KDR, PIK3CB, PTPN1, SRC, XDH |
2.2687 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.26153 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.26153 |
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ALOX15, BCL2, CDC25B, CSNK2A1, ESR1, FLT3, HTR2A, HTR2B, HTR2C, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
2.25333 |
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, MMP2, MMP9 |
2.25241 |
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, PTGS1, PTGS2, TBXAS1 |
2.25241 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.25241 |
[BP] GO:0009966 |
regulation of signal transduction
|
AKR1B1, ALOX15, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, ESR1, FLT3, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TNKS, TNKS2, XDH |
2.24771 |
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.23958 |
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
CNR1, HTR1B, HTR2A, PTGS2 |
2.23958 |
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, HTR2A, HTR2B, HTR2C, KDR, PTPN1, SRC |
2.23958 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.22271 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA3, AKR1B1, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, ESR1, FABP3, FABP4, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, RORC, SRC, TNKS, TNKS2, XDH |
2.21893 |
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9 |
2.21893 |
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.21893 |
[BP] GO:0043269 |
regulation of ion transport
|
BCL2, CA2, CA7, CHRM1, CNR1, HTR1A, HTR1B, HTR2A, MMP9, PTGS2 |
2.20142 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, HTR1B, KDR, PTGS2, SRC |
2.18084 |
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.18084 |
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.18084 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.18084 |
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.18084 |
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.18084 |
[BP] GO:0095500 |
None
|
CHRM1, CHRM2, CHRM4 |
2.18084 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.18084 |
[BP] GO:1903831 |
None
|
CHRM1, CHRM2, CHRM4 |
2.18084 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, AURKB, AXL, BCL2, CNR1, ESR1, IGF1R, KDR, MET, MMP1, MMP9, SRC, TNKS, TNKS2 |
2.17758 |
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, ESR1, HTR7, RORC, SRC |
2.17273 |
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, FUT7, HTR2B, HTR6, KDR, MET, MMP1, MMP9, PIK3CA, PIK3CB, SRC |
2.17273 |
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, HTR2A, HTR2B, HTR2C, KDR, SRC |
2.1552 |
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.13685 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AXL, CYP1B1, ESR1, IGF1R, MMP2, MMP9, PIK3CA, PTGS2, RORC, SRC |
2.13536 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.13536 |
[BP] GO:0070482 |
response to oxygen levels
|
BCL2, CYP1A1, HSD11B2, MMP2, POLB, PTGS2, SRC |
2.11614 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC |
2.11187 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, ESR1, HSD11B2, HSD17B2, MMP2, MMP9, PTGS2, SRC |
2.08609 |
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, HTR1B, MMP2, MMP9, PTGS2 |
2.0664 |
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, ESR1, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
2.05334 |
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ALOX15, BCL2, CDC25B, ESR1, FLT3, HTR2A, HTR2B, HTR2C, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, XDH |
2.05161 |
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.04536 |
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.04308 |
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, HSD11B2, PTGS2, SRC, TYR |
2.04262 |
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, FUT7, HTR2B, HTR6, KDR, MMP1, MMP9, PIK3CA, PIK3CB, SRC |
2.02915 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, MET, PIK3CA, PIK3CB, SRC, XDH |
2.01522 |
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.00379 |
[BP] GO:0007271 |
None
|
CHRM1, CHRM2, CHRM4 |
2.00379 |
[BP] GO:0071502 |
None
|
HTR1B, HTR2B |
2.00083 |
[CC] GO:0016020 |
membrane
|
ACHE, ADORA3, ALOX15, ALOX5, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FLT3, FUT7, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TNKS, TNKS2, TYR |
6.28693 |
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA3, AXL, CA4, CHRM1, CHRM2, CHRM4, CNR1, CNR2, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET |
6.28043 |
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET |
5.92327 |
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA3, ALOX15, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FLT3, FUT7, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, MPEG1, PIK3CA, PIK3CB, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TYR |
5.84952 |
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA3, ALOX15, ALPL, AXL, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, ESR1, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PTPN1, SRC |
5.15339 |
[CC] GO:0044459 |
plasma membrane part
|
ADORA3, ALOX15, AXL, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, PTGS2, SRC |
4.73977 |
[CC] GO:0031224 |
None
|
ACHE, ADORA3, ALPL, AXL, CA12, CA14, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, ESR1, FLT3, FUT7, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, MPEG1, TBXAS1, TYR |
2.21893 |
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
20.3843 |
[MF] GO:0008227 |
None
|
CHRM1, CHRM2, CHRM4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
17.8073 |
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
17.1934 |
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
17.1934 |
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
16.968 |
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
16.968 |
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.2042 |
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
11.1907 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX15, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FLT3, HSD17B1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, KDR, MET, MMP1, MMP2, MMP9, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, RORC, SRC, TBXAS1, TNKS, TNKS2, TYR, XDH |
10.4126 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.1522 |
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
9.81193 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, MMP1, MMP2, MMP9, NQO2, PIM1, PTPN1, RORC, TBXAS1, TNKS, TYR, XDH |
9.56114 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, MMP1, MMP2, MMP9, NQO2, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, RORC, TBXAS1, TNKS, TNKS2, TYR, XDH |
8.01556 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, FUT7, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP2, MMP9, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TNKS, TNKS2, TYR, XDH |
7.47214 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, ESR1, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, RORC |
7.36478 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
7.1295 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, POLB |
6.69224 |
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET |
6.67174 |
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET |
6.67174 |
[MF] GO:0004872 |
receptor activity
|
ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, ESR1, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, RORC |
6.47436 |
[MF] GO:0060089 |
molecular transducer activity
|
ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, ESR1, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, RORC |
6.28693 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.28043 |
[MF] GO:0004871 |
signal transducer activity
|
ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, ESR1, FLT3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, KDR, MET, RORC |
5.82591 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MET, NQO2, PIK3CA, PIK3CB, PIM1, SRC |
5.76698 |
[MF] GO:0004930 |
None
|
ADORA3, CHRM1, CHRM2, CHRM4, CNR1, CNR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
5.44531 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD11B2, HSD17B1, NQO2, POLA1, PTGS1, PTGS2, SRC, TBXAS1, XDH |
5.28628 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, SRC, TBXAS1 |
5.24703 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, SRC, TBXAS1 |
5.0157 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2, TBXAS1, TYR |
4.68568 |
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, TBXAS1, XDH |
4.5914 |
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, POLB |
4.17167 |
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM4 |
4.08024 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
3.94585 |
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, ESR1, MMP1, MMP2, MMP9, NQO2, PTPN1, RORC, TNKS |
3.69374 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TBXAS1, TYR |
3.67566 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.66124 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.4716 |
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.41166 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.35857 |
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.30325 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.18792 |
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, MMP1, MMP2, MMP9, NQO2, PIM1, POLA1, POLB, PTGS1, PTGS2, PTPN1, RORC, TBXAS1, TNKS, TNKS2, TYR, XDH |
3.03987 |
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, PIK3CA, PIK3CB |
3.02173 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
2.90106 |
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.81853 |
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.81853 |
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.81853 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
2.62586 |
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM4 |
2.43639 |
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.41359 |
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.41359 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, NQO2, XDH |
2.347 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.30551 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIK3CA, PIK3CB, PIM1, POLA1, POLB, SRC |
2.20713 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX15, ALOX5, PTGS2 |
2.04308 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIK3CA, PIK3CB, PIM1, SRC |
2.00379 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX15, ALOX5, PTGS2 |
2.00379 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIK3CA, PIM1, SRC |
2.00083 |