| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CHRM1, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KDR, KIT, MAOA, MET, MIF, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS1, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
24.025 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ABCG2, AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IDO1, IGF1R, INSR, KDR, KIT, MMP2, MMP9, MPO, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TOP1, TRPV1, TYR |
18.4248 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HTR1B, HTR5A, IDO1, IGF1R, INSR, MMP2, MMP9, MPO, PIK3CA, POLB, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
17.6657 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IDO1, IGF1R, INSR, KDR, KIT, MMP2, MPO, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
16.5527 |
|
[BP] GO:0007187 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, GRM1, GRM3, GRM5, GRM8, HRH3, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
15.357 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.3029 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.3029 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, DRD2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
14.1053 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.822 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.7641 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TRPV1 |
13.4787 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, ABCG2, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, EGFR, FABP3, HMGCR, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KDR, POLB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TOP1, TRPV1 |
12.7591 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH4, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.7139 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
12.5718 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH4, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.4668 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA7, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HRH3, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KCNA3, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
12.2291 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GRIK5, GRM1, GRM5, HMGCR, HRH4, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IDO1, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP1, TOP2A, TRPV1, TYR |
12.1886 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
12.1487 |
|
[BP] GO:0007188 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
12.0084 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1B1, DNMT1, DRD2, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IDO1, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, PRKCA, PTAFR, PTGES, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
11.9333 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
11.8285 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.7189 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
11.7129 |
|
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
11.5804 |
|
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
11.5804 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, PRKCE, PTGS2 |
11.5405 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, KIT, PRKCE, PTGS2 |
11.5405 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESRRA, FLT3, HSD11B2, HTR1B, HTR5A, PRKCE, PRKCG, PTAFR, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
11.3758 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, PTGS2 |
11.2668 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, FABP3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR2B, HTR2C, IDO1, MIF, MPO, PIK3CA, PIM1, PPARA, PTAFR, PTGES, PTGS1, PTGS2, TBXAS1, TYR, XDH |
11.2668 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, HRH3, HRH4, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.0744 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.0316 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, HRH3, HRH4, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.9643 |
|
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM4, DRD1, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
10.7953 |
|
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM4, DRD1, DRD2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
10.7953 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IDO1, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.7697 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.7566 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CYP19A1, DRD1, DRD2, EGFR, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HRH3, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, KCNA3, MIF, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
10.7566 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, HTR1B, HTR5A, IDO1, MPO, PRKCE, PTAFR, PTGES, PTGS2, RORC, SRC, TYR |
10.6937 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
10.6688 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, CNR1, DRD1, DRD2, EGFR, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
10.55 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, GPR35, GRM1, HMGCR, HRH4, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
10.4575 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AXL, BCL2, CA1, CA2, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
10.4474 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, GRM5, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, KIT, MMP2, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1 |
10.3563 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AXL, BCL2, CHRM1, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GRM1, GRM5, GRM8, HMGCR, HRH3, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IDO1, IGF1R, INSR, KIT, MET, MMP1, MMP12, MMP2, MMP9, MPO, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TOP1, TRPV1, TYR |
10.1278 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CHRM1, CHRM4, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HTR1D, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
9.99542 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, POLA1, POLB, PRKCB, PRKCE, SMAD3, SRC, TERT, TRPV1 |
9.92074 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MIF, MMP9, MPO, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
9.92074 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGES, PTGS1, PTGS2, TBXAS1 |
9.82546 |
|
[BP] GO:0003018 |
None
|
ADORA1, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
9.82546 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.78509 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.78509 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.54271 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.4637 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, EGFR, GRM1, HMGCR, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, KIT, MMP2, MPO, POLB, PPARA, PRKCB, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
9.44167 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, TOP1, XDH |
9.40553 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, PIM1, PRKCA, PTAFR, PTGS2, TEK, TERT |
9.36594 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP9, MPO, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.32136 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, APP, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, PTAFR, SRC |
9.30637 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, INSR, KIT, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TEK, TRPV1 |
9.27237 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HMGCR, HRH3, HRH4, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, MPO, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.19737 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CES2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, KIT, MET, MIF, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
9.18865 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, HTR2C, PRKCA, PRKCE, SLC22A1 |
9.1521 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.11116 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
9.07167 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, MMP9, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TERT, TRPV1 |
8.86918 |
|
[BP] GO:0097746 |
None
|
ADORA1, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.80197 |
|
[BP] GO:0035296 |
None
|
ADORA1, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.80197 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, TOP1, XDH |
8.7942 |
|
[BP] GO:0097756 |
None
|
ADORA1, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
8.73971 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, AKR1B1, APP, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, EGFR, ESR1, FABP3, FABP4, GPR35, GRIK5, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.73265 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, EGFR, FABP3, FLT3, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
8.72231 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
8.71119 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
8.71119 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
8.70566 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HRH4, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.60159 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
8.59228 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MAOA, MPO, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
8.59228 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DRD2, DUSP3, EGFR, FLT3, GRM1, HMGCR, HRH4, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
8.54032 |
|
[BP] GO:0050880 |
None
|
ADORA1, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.51038 |
|
[BP] GO:0035150 |
None
|
ADORA1, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2 |
8.47224 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
8.3813 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IDO1, IGF1R, KDR, MIF, MMP9, MPO, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.35719 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DRD2, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
8.35719 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, KIT, MMP9, PRKCD, PTGES, PTGS2, SRC, TERT |
8.32506 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.29968 |
|
[BP] GO:0003013 |
None
|
ADORA1, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTAFR, PTGS2, SRC, TEK |
8.25935 |
|
[BP] GO:0007267 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1, TEK |
8.25696 |
|
[BP] GO:0007154 |
None
|
ADORA1, AXL, BCL2, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, PTGS2, SLC1A1, TEK, TRPV1 |
8.21159 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP1 |
8.17443 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IDO1, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, MPO, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.17138 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, HTR2A, HTR2B, HTR2C, MIF, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
8.07614 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.07503 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, EGFR, FABP3, FLT3, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
8.05202 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
8.03237 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2, DRD2, HTR1B, PRKCE |
7.9741 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
7.96994 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, EGFR, GRIK5, HRH3, HTR1A, INSR, MAOA, PTGS2, SLC1A1, SLC22A2, SLC22A3, SMAD3, TRPV1 |
7.96549 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
7.96048 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD1, DRD2, EGFR, GRM1, GRM5, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IDO1, INSR, KIT, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
7.95072 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IDO1, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
7.9229 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.88458 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
7.85895 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM3, GRM5, HMGCR, HRH3, HRH4, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
7.84552 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, APP, BCL2, CA2, CA7, CHRM1, CNR1, DRD1, DRD2, GPR35, GRM5, HRH3, HTR1A, HTR1B, HTR2A, KCNA3, MIF, MMP9, PRKCD, PRKCE, PTAFR, PTGS2 |
7.76599 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
7.76066 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, HMGCR, HTR1B, HTR1D, KDR, POLB, PRKCD, PRKCE, SRC |
7.70277 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, GRM1, GRM5, HMGCR, HRH4, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.60457 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
7.60457 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, FABP3, FLT3, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, KIT, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
7.55056 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
7.44724 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CDK6, CYP1B1, DNMT1, DRD1, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, PIK3CA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SRC, TRPV1 |
7.44583 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HRH4, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
7.42722 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.42032 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
7.42032 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MIF, MMP1, MMP2, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
7.417 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HRH4, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.40992 |
|
[BP] GO:0023052 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1, TEK |
7.39932 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.36474 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.30903 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, IDO1, MIF, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
7.30903 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GRM1, GRM3, GRM5, HMGCR, HRH3, HRH4, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MET, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
7.20634 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TERT |
7.17618 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.02698 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM1, GRM5, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MIF, MMP2, MMP9, NUAK1, PIK3CA, POLA1, POLB, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
7.01082 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.98988 |
|
[BP] GO:0007200 |
None
|
CHRM1, CHRM2, CHRM4, DRD1, DRD2, ESR1, GRM5, HTR2A, HTR2B, HTR2C |
6.96975 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
6.89623 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
6.89623 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP1 |
6.85274 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, APP, BCL2, CHRM1, CNR1, CNR2, CYP1B1, DRD1, DRD2, EGFR, GRM1, GRM5, GRM8, HMGCR, HRH3, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, KIT, PIK3CA, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
6.77983 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, APP, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CNR1, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IDO1, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPRS, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
6.77098 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CHRM1, CNR1, DRD1, DRD2, EGFR, GRM5, HMGCR, HRH3, HTR2A, INSR, KIT, PRKCG, PTGS2 |
6.69866 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, DUSP3, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PRKCA, PTPN1, SRC, TEK |
6.66004 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, EGFR, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.65398 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.64809 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.64495 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TUBB3, TYR, XDH |
6.63568 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CHRM4, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
6.61276 |
|
[BP] GO:0030815 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, PRKCA |
6.61077 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRM1, HMGCR, HRH4, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
6.58259 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, PIM1, PRKCG, SRC, TEK |
6.57748 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, PRKCA, SRC, TEK |
6.55288 |
|
[BP] GO:1900543 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, PPARA, PRKCA |
6.54347 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, GRIK5, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.53624 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, HTR1B, KDR, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TRPV1 |
6.52024 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
6.49823 |
|
[BP] GO:0045980 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, PPARA, PRKCA |
6.49823 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.49823 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, DRD1, DRD2, EGFR, ESR1, F3, FABP4, HMGCR, IDO1, KDR, MET, MIF, MMP12, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPRS, SMAD3, TEK |
6.49279 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ESR1, HTR7, KIT, PPARA, PRKCG, RORC, SRC, TOP1, TOP2A |
6.49279 |
|
[BP] GO:0030800 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, PRKCA |
6.49279 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.47234 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.47234 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, GRIK5, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, POLA1, PRKCB, PRKCE, SMAD3, TRPV1 |
6.47234 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS, TOP1 |
6.4379 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, POLB, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.36577 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, IDO1, KDR, KIT, MET, MIF, MMP12, MMP9, PIM1, PRKCA, PRKCB, PRKCE, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
6.33471 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
6.3338 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
6.3338 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTAFR, PTGS2, TERT |
6.31937 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, HTR2A, HTR2B, HTR2C, KDR, PRKCE, SRC, TRPV1 |
6.315 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5, PTAFR |
6.29249 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.29211 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, HRH4, HSD11B2, HSPA1A, HTR1A, HTR2C, IDO1, KIT, MIF, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
6.27408 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, EGFR, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
6.25222 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.22051 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DUSP3, ESR1, FABP4, GPR35, GRM3, HMGCR, HRH3, HRH4, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
6.20309 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.19045 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD1, DRD2, EGFR, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.1695 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA6, CA7, CA9 |
6.16422 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, MPO, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCD, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
6.15683 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.14128 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD2, GPR35, HRH3, HTR1B, HTR2A, MMP9, PRKCE, PTGS2 |
6.14128 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGES, PTGS1, PTGS2, TBXAS1 |
6.0677 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, GRM5, HRH3, MIF, PRKCD, PTAFR |
6.06429 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.03369 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, GBA2, HMGCR, HTR1A, MAOA, PTAFR, TYR |
5.99788 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
5.98749 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS, TOP1 |
5.9668 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, NQO2, PTGS1, RORC |
5.95598 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD2, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
5.94372 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
5.91969 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, CNR2, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
5.91667 |
|
[BP] GO:0090066 |
None
|
ADORA1, ALOX15, CHRM1, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PRKCD, PRKCE, PTAFR, PTGS2 |
5.8975 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, BCL2, CHRM1, CHRM4, CYP1A1, EGFR, ESR1, FLT3, HTR1A, KIT, MET, MIF, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TYR |
5.8975 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, CNR2, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
5.89158 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
5.851 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, HTR2A, MIF, MPO, POLB, PRKCD, PTGS2, TERT |
5.83411 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
5.83395 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, APP, BCL2, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.79041 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, ESRRB, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, HTR2A, INSR, PPARA, PRKCA |
5.77456 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, APP, BCL2, DRD1, DRD2, EGFR, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.76789 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, EGFR, GRIK5, HCAR2, HMGCR, HRH3, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PRKCA, PRKCE, PTAFR, SRC, TRPV1 |
5.74049 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD1, DRD2, HTR1B, HTR2A, PTGS2 |
5.72336 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
5.72336 |
|
[BP] GO:0006855 |
None
|
ABCB1, ABCG2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
5.72336 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
5.65194 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, DYRK1A, EGFR, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP1, TOP2A |
5.65174 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, ESRRB, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, HTR2A, INSR, PPARA, PRKCA |
5.64007 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
5.63415 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, EGFR, GRIK5, HCAR2, HMGCR, HRH3, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, PRKCA, PRKCE, PTAFR, SRC |
5.61779 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, ESR1, FLT3, GRM5, HTR1B, IGF1R, INSR, KIT, MMP2, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
5.6086 |
|
[BP] GO:0030818 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
5.59346 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F3, FLT3, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, KIT, MET, MIF, MMP9, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.59346 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, DRD1, DRD2, EGFR, HCAR2, HTR2B, INSR, MIF, MMP12, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TERT, TRPV1 |
5.53139 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, GRM5, HTR1B, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
5.53139 |
|
[BP] GO:0030803 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
5.46561 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DNMT1, DRD2, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HRH3, HRH4, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MET, MIF, MMP12, MMP9, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
5.42089 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, DRD2, EGFR, GPR35, GRM1, HCAR2, HTR2A, HTR2C, KIT, PRKCA, PTAFR, PTGS2, SLC1A1, SMAD3, TRPV1 |
5.3852 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, IDO1, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, PTPRS, SMAD3, SRC |
5.37491 |
|
[BP] GO:0006939 |
None
|
DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, TRPV1 |
5.33887 |
|
[BP] GO:0042310 |
None
|
HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
5.32984 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.30597 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, EGFR, HSPA1A, IDO1, MAOA, MPO |
5.28406 |
|
[BP] GO:1900372 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
5.28406 |
|
[BP] GO:0030809 |
None
|
DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
5.28406 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
5.23215 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
5.23215 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.13317 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.13317 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
5.12685 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, KIT, MMP9, PTGES, PTGS2, TERT |
5.11697 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, GRM5, HTR1B, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
5.09028 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD1, DRD2, EGFR, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
5.07566 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.06531 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.05032 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.03854 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.02945 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2 |
5.01403 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
5.01073 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, HRH4, KIT, MIF, PIK3CA, PIK3CB, POLB, PTAFR, PTGES, PTGS1, PTGS2, TRPV1 |
5.00774 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, KIT, MIF, MMP9, MPO, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, RORC, SMAD3, SRC, TRPV1 |
5.00209 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, HTR2A, KIT, MIF, PRKCD, PRKCE, PTPN1, SRC |
4.98845 |
|
[BP] GO:0015893 |
None
|
ABCB1, ABCG2, CA2, DRD1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.98518 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HRH4, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.98463 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.97215 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, IDO1, MIF, MPO, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.95956 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD1, DRD2, EGFR, GRM5, HMGCR, HTR2A, INSR, KIT, PRKCG, PTGS2 |
4.91619 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, GRM5, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, KIT, MET, MIF, NUAK1, PIK3CA, PIK3CB, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, SRC, TEK |
4.9006 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPL, AOX1, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, CYP3A4, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
4.88187 |
|
[BP] GO:0030814 |
None
|
DRD1, DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, PRKCA |
4.87613 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HRH4, HTR2A, HTR2B, HTR2C, PRKCE, SMAD3, TRPV1 |
4.87613 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
4.79752 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
4.78777 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.77921 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, MPO, PRKCD, PTGS1, PTGS2, SRC |
4.7736 |
|
[BP] GO:0006811 |
None
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD1, DRD2, FABP3, GRIA2, GRIA4, GRIK5, HTR2A, HTR2B, HTR2C, KCNA3, PPARA, PRKCB, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
4.76621 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD1, DRD2, EGFR, PRKCE, PTGS2 |
4.7315 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
4.7315 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GRM5, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
4.68917 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.67669 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, IDO1, MMP12, MMP2, PPARA, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK |
4.66725 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, PTAFR, PTGS2, RORC, SRC, TRPV1 |
4.6632 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, IDO1, MIF, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.66245 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.64551 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.64551 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.61332 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTAFR, PTGS2, TERT |
4.53827 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, IDO1, MIF, MPO, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.53303 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
4.52654 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.52607 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, KIT, PIK3CA, POLB, PPARA, PTPRS, SMAD3, SRC, TEK, TYR |
4.48368 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CHRM1, CNR1, DRD2, EGFR, HCAR2, HMGCR, HTR2B, HTR2C, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.46312 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, DRD2, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
4.45303 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CNR1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A, HTR2A, HTR2C, PRKCA, PRKCE |
4.43501 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
4.41879 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.39762 |
|
[BP] GO:0030817 |
None
|
DRD1, DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
4.39762 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DUSP3, EGFR, INSR, MIF, PRKCA, PRKCE, SRC, TERT |
4.39762 |
|
[BP] GO:0045913 |
None
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, PTAFR, SRC |
4.37705 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNA3, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
4.3274 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HRH3, HRH4, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.29136 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.27977 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.24923 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.24923 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
4.2392 |
|
[BP] GO:0030799 |
None
|
DRD1, DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, HTR1E, PRKCA |
4.18679 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, DRD1, DRD2, HMGCR, MIF, PPARA, PRKCD, PTPRS, SMAD3, TEK |
4.18416 |
|
[BP] GO:0006693 |
None
|
CES2, MIF, PTGES, PTGS1, PTGS2 |
4.15067 |
|
[BP] GO:0006692 |
None
|
CES2, MIF, PTGES, PTGS1, PTGS2 |
4.15067 |
|
[BP] GO:0015872 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
4.09685 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
4.09685 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.09685 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD1, DRD2, EGFR, HTR1B, PRKCE, PRKCG, PTAFR |
4.09439 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DUSP3, DYRK1A, ESR1, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
4.09439 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, EGFR, HMGCR, HSPA1A, IGF1R, MET, MIF, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, PTPRS, TERT, XDH |
4.08223 |
|
[BP] GO:0051952 |
None
|
ADORA1, CNR1, DRD1, DRD2, HRH3, HTR1B, HTR2A |
4.06835 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
4.04424 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HRH4, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.0441 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CNR1, CNR2, DRD1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
4.04409 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.04409 |
|
[BP] GO:0008217 |
None
|
ADORA1, CNR1, DRD2, HSD11B2, PPARA, PTAFR, PTGS1, PTGS2, SMAD3 |
4.03482 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.03104 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HRH3, HRH4, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.00932 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AURKB, CSNK2A1, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HRH3, HRH4, HSPA1A, HTR1B, HTR1E, IGF1R, MIF, MMP12, MMP9, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.00906 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
4.00892 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, HTR1A, MAOA, TYR |
4.00892 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, DRD1, PRKCA, PRKCB, PRKCD |
4.00848 |
|
[BP] GO:0001516 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
3.96621 |
|
[BP] GO:0046457 |
None
|
MIF, PTGES, PTGS1, PTGS2 |
3.96621 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX15, MIF, PTGES, PTGS1, PTGS2 |
3.93227 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CDK6, CYP1B1, DUSP3, IDO1, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, SMAD3, SRC, TEK |
3.92057 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, SRC |
3.90966 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA, PRKCD, PRKCE |
3.90966 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, HTR1B, PTAFR, PTGS2, SRC |
3.90841 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
DRD1, DRD2, ESR1, GPR35, GRM1, HRH4, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.89536 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CHRM1, CNR1, CNR2, CYP1B1, DRD1, DRD2, EGFR, GRM1, GRM5, GRM8, HMGCR, HRH3, HTR2A, INSR, KIT, PRKCG, PTGS2, TRPV1, TYR |
3.86701 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.86626 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA3, ALOX15, APP, AXL, BCL2, CNR2, DRD1, HRH4, HTR1A, HTR2C, KIT, MIF, MPO, PIK3CA, PIK3CB, POLB, PRKCD, PTAFR, PTGES, PTGS1, PTGS2, SRC, TRPV1 |
3.84699 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, HTR2A, MET, PIK3CA, TRPV1 |
3.84286 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, KIT, PRKCD, PTAFR, PTGS2 |
3.84157 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
3.83706 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR1B, HTR2A |
3.83706 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
BCL2, DRD1, HTR1A, HTR2C, IDO1, PRKCG |
3.82374 |
|
[BP] GO:0030802 |
None
|
DRD1, DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
3.82298 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.81999 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, HTR2A, TRPV1 |
3.8028 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.8028 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
3.78372 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.7519 |
|
[BP] GO:0007194 |
None
|
DRD2, GRM3, HRH3, HRH4, PRKCA |
3.73587 |
|
[BP] GO:0051937 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.71781 |
|
[BP] GO:0097553 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.69575 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM4 |
3.69379 |
|
[BP] GO:0071502 |
None
|
HTR1B, HTR2B, TRPV1 |
3.69379 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.69379 |
|
[BP] GO:0060359 |
None
|
CNR1, DRD1, DRD2, HTR1B, PRKCE, PRKCG, PTAFR |
3.69298 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD2, GPR35, HMGCR, HRH3, HSPA1A, HTR1B, HTR2A, MMP9, PRKCB, PRKCE, PTGS2 |
3.69216 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, HMGCR |
3.68213 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
3.68213 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
3.68206 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.67971 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.65942 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
3.63686 |
|
[BP] GO:0051588 |
None
|
DRD1, DRD2, GRIK5, HRH3, HTR1A, HTR1B, HTR2C |
3.63686 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
3.63686 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, HMGCR, IDO1, MIF, MPO, PTAFR, PTGES, PTGS1, PTGS2 |
3.63378 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
3.62569 |
|
[BP] GO:0031280 |
None
|
DRD2, GRM3, HRH3, HRH4, PRKCA |
3.62242 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTAFR, PTGES, PTGS2, SRC |
3.62069 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.61817 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, CNR1, DNMT1, DRD2, ESR1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.61701 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, MMP12, PPARA, PRKCD, SMAD3, TEK |
3.60437 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, PTAFR, SRC, TRPV1 |
3.59683 |
|
[BP] GO:1900371 |
None
|
DRD1, DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
3.59657 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, HTR1B, PTAFR, PTGS2, SRC |
3.58792 |
|
[BP] GO:0030808 |
None
|
DRD1, DRD2, GRM3, GRM8, HRH3, HRH4, HTR1B, PRKCA |
3.57366 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.56708 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
3.55223 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
3.55081 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, PTAFR, SRC, TEK |
3.5345 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DRD2, DUSP3, ESR1, HSPA1A, IDO1, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, PTPRS, SMAD3, SRC |
3.5345 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, IDO1, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.5345 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CYP1B1, F3, KDR, KIT, PRKCA, PRKCB, PTGS2, TEK, TERT |
3.5345 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, CHRM1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.52463 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
3.51849 |
|
[BP] GO:0051350 |
None
|
DRD2, GRM3, HRH3, HRH4, PRKCA |
3.5155 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CNR1, DRD2, EGFR, HCAR2, HMGCR, HTR2B, HTR2C, MIF, MMP12, PRKCA, PRKCE, SRC |
3.51284 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.506 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PTGES, PTGS2, SRC |
3.50042 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, IDO1, KDR, MET, MIF, PRKCA, PTGS2, SMAD3 |
3.4718 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, EGFR, PPARA, SMAD3 |
3.46454 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TERT, TNKS, TOP2A |
3.45916 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, GRM5, HMGCR, INSR, KIT, PTGS2 |
3.44901 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
3.44901 |
|
[BP] GO:0060402 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.44901 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB, PTAFR |
3.44901 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, IDO1, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.44671 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM4 |
3.44556 |
|
[BP] GO:0032229 |
None
|
ADORA1, CNR2, HTR1B |
3.44556 |
|
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.44556 |
|
[BP] GO:0045936 |
None
|
DRD2, DUSP3, FABP4, GRM3, GRM8, HMGCR, HRH3, HRH4, HTR1B, HTR1E, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
3.44258 |
|
[BP] GO:0010563 |
None
|
DRD2, DUSP3, FABP4, GRM3, GRM8, HMGCR, HRH3, HRH4, HTR1B, HTR1E, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
3.43437 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR1D, HTR2B |
3.43426 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM1, CHRM2, KIT, PTAFR, PTGS2 |
3.41893 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TERT, TNKS |
3.38245 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, IDO1, MIF, MMP12, PTPRS |
3.34913 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.34777 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CHRM1, CNR1, DRD2, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.32991 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, EGFR, HMGCR, HSD11B2, HTR2A, IDO1, KIT, MMP12, MPO, PRKCD, PTAFR, PTGES, PTGS2, SMAD3, SRC, TRPV1, TYR |
3.31556 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
3.31415 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.29983 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
3.29119 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DUSP3, INSR, PRKCA, TERT |
3.28897 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR, IDO1 |
3.2795 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, HTR5A, INSR, KDR, KIT, MMP9, PIK3CA, PIM1, POLB, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TYR |
3.27283 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.26529 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.26529 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MPO, PTGES, PTGS2, SRC |
3.26166 |
|
[BP] GO:0032409 |
None
|
ABCB1, APP, BCL2, DRD2, GPR35, GRM5, MMP9, PRKCD, PRKCE, PTAFR |
3.25754 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, CHRM1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.24515 |
|
[BP] GO:0040016 |
embryonic cleavage
|
PIK3CB, TOP1, TOP2A |
3.23049 |
|
[BP] GO:0009820 |
alkaloid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.23049 |
|
[BP] GO:0014062 |
None
|
HRH3, HTR1A, HTR1B |
3.23049 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.23049 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.23049 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
3.22166 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, PPARA, PTAFR |
3.22166 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR |
3.20808 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DUSP3, EGFR, HSPA1A, INSR, MIF, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
3.2012 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.18424 |
|
[BP] GO:0015844 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.17996 |
|
[BP] GO:0045934 |
None
|
APEX1, AURKB, DNMT1, DRD2, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HRH3, HRH4, HSPA1A, HTR1B, HTR1E, MMP12, PPARA, PRKCA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
3.1777 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, HMGCR, HTR2A, HTR2C, IDO1, INSR, KDR, KIT, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT |
3.14419 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
3.12938 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CHRM1, CNR1, DRD2, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.10535 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
3.10418 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
3.10317 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
3.10317 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AURKB, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.10317 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, HTR2A, HTR2C, IDO1, INSR, KDR, KIT, MIF, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
3.10317 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, SRC, TRPV1, TYR |
3.10122 |
|
[BP] GO:0045761 |
None
|
DRD2, GRM3, HRH3, HRH4, PRKCA |
3.08844 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, SRC |
3.0854 |
|
[BP] GO:0051282 |
None
|
DRD1, DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.07053 |
|
[BP] GO:0060401 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.06814 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, BCL2, CHRM1, CNR1, CSNK2A1, DRD2, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.05415 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, GRM1, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.05415 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC, TERT |
3.05415 |
|
[BP] GO:0042737 |
drug catabolic process
|
ACHE, CYP1A2, CYP2A6, CYP2D6, CYP3A4, MAOA, MPO |
3.05233 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.05233 |
|
[BP] GO:0051234 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CHRM1, DRD1, DRD2, EGFR, F10, FABP3, GRIA2, GRIA4, GRIK5, HRH3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KCNA3, KIT, MIF, MMP12, MMP9, MPO, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TERT, TNKS, TRPV1, XDH |
3.04657 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.043 |
|
[BP] GO:0051953 |
None
|
ADORA1, CNR1, DRD2, HRH3 |
3.0376 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.0376 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, PRKCD, SMAD3, TEK |
3.03182 |
|
[BP] GO:0050433 |
None
|
CNR1, DRD2, HRH3, HTR1B, HTR2A |
3.00885 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.00885 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
2.96689 |
|
[BP] GO:0032098 |
None
|
HTR2C, HTR4, PPARA, SLC22A3 |
2.96689 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MPO |
2.96689 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, HMGCR, KIT |
2.96689 |
|
[BP] GO:1901570 |
None
|
ALOX15, ALOX5, MIF, PTGES, PTGS1, PTGS2 |
2.95608 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PRKCD, PTAFR, PTGES, PTGS2, SMAD3, SRC |
2.94372 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
2.91955 |
|
[BP] GO:0048169 |
None
|
APP, DRD2, GRM5, KIT |
2.8991 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, IDO1, MIF, PIK3CB |
2.8991 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
2.8991 |
|
[BP] GO:0010359 |
None
|
ABCB1, GRM5, PTAFR |
2.8991 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, FABP3, FABP4, FUT7, GBA2, HSPA1A, IDO1, MAOA, MMP1, MMP12, MMP2, MMP9, MPO, PIK3CB, SRC, XDH |
2.87579 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
2.83531 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT, PTAFR |
2.8189 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.81026 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
2.79837 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, CHRM1, DRD2, F10, F3, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
2.79821 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, GRM5, HTR2A, KIT, MIF, PTPN1, SRC |
2.77963 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, HMGCR, KIT |
2.77601 |
|
[BP] GO:0051179 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ALOX15, ALOX5, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CHRM1, DRD1, DRD2, EGFR, ESR1, F10, FABP3, GRIA2, GRIA4, GRIK5, HRH3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KCNA3, KIT, MIF, MMP12, MMP9, MPO, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.76619 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
2.76572 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.7614 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, MPO, PTGS2, SRC, TRPV1, TYR |
2.7523 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
2.75038 |
|
[BP] GO:0006810 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CHRM1, DRD1, DRD2, F10, FABP3, GRIA2, GRIA4, GRIK5, HRH3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KCNA3, KIT, MIF, MMP12, MMP9, MPO, PPARA, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
2.7485 |
|
[BP] GO:0022898 |
None
|
ABCB1, APP, BCL2, DRD2, GPR35, GRM5, MMP9, PRKCE, PTAFR |
2.7295 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, IDO1, MMP12, MPO, PRKCD, PTAFR, PTGES, PTGS2, SMAD3, SRC |
2.7295 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.72584 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC, TERT |
2.72584 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
2.72584 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
2.72584 |
|
[BP] GO:0051482 |
None
|
DRD1, GPR35, GRM1, HTR2C |
2.72584 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.72584 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD2, HTR1B, HTR2A |
2.72584 |
|
[BP] GO:2001023 |
None
|
CNR1, DRD1, DRD2, HTR1B, HTR2A, MET |
2.72584 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, EGFR, HMGCR, KIT, PTGS2, TYR |
2.72584 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, DRD2, EGFR, HTR2A, PTAFR, PTGS2, SLC1A1 |
2.72584 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AURKB, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, PPARA, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.7207 |
|
[BP] GO:0032768 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
2.71272 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.7054 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.7054 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.7054 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.7054 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, GRM1, GRM5, HTR2C, IDO1, PRKCE |
2.70114 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, KIT, MMP9, TERT |
2.68426 |
|
[BP] GO:0043279 |
None
|
CNR1, DRD2, HTR1B, PRKCE, PRKCG, TRPV1 |
2.68408 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, HTR1A, MAOA |
2.65346 |
|
[BP] GO:0002031 |
None
|
DRD2, HTR1B, HTR2B |
2.65346 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.65346 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, SRC |
2.65346 |
|
[BP] GO:0072347 |
None
|
CNR1, DRD2, HTR1B, PRKCE, PRKCG |
2.65346 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.65346 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GRM1, GRM5, HMGCR, HRH4, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
2.64486 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
2.62817 |
|
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.628 |
|
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.628 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.628 |
|
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, EGFR, MPO |
2.628 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, PTAFR, SRC |
2.628 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DYRK1A, EGFR, HTR7, PPARA, RORC, TOP1 |
2.628 |
|
[BP] GO:0050708 |
None
|
ACHE, CNR1, DRD2, EGFR, HCAR2, HMGCR, HTR2B, MIF, MMP12, PRKCA, PRKCE, SRC |
2.59771 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.59021 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6, CYP3A4 |
2.59021 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTAFR, PTGS2 |
2.57163 |
|
[BP] GO:0019229 |
None
|
CHRM1, EGFR, HTR2A, PTAFR, PTGS2 |
2.55639 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, EGFR, HSPA1A, INSR, MIF, PRKCE, TERT, TNKS |
2.54699 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.54668 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.54668 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.54668 |
|
[BP] GO:0070989 |
oxidative demethylation
|
CYP1A2, CYP2D6, CYP3A4 |
2.54668 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, IDO1, INSR, KIT, MMP2, MMP9, PTAFR, PTGS2, SRC, TOP2A |
2.53965 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.53072 |
|
[BP] GO:0031279 |
None
|
DRD2, GRM3, HRH3, HRH4, PRKCA |
2.53072 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, PPARA, PRKCG, RORC, TOP2A |
2.53072 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.53072 |
|
[BP] GO:0043278 |
None
|
CNR1, DRD2, PRKCE, PRKCG |
2.53072 |
|
[BP] GO:0014072 |
None
|
CNR1, DRD2, PRKCE, PRKCG |
2.53072 |
|
[BP] GO:0042596 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.53072 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CNR1, CNR2, CSNK2A1, DRD2, DUSP3, FABP4, GRM3, HMGCR, HRH3, HRH4, IGF1R, MMP9, PRKCA, PRKCD, PTGS2, PTPN1, SRC |
2.50758 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, PIK3CA, PTGS2 |
2.50758 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, TRPV1, TYR |
2.50215 |
|
[BP] GO:0051339 |
None
|
DRD2, GRM3, HRH3, HRH4, PRKCA |
2.50165 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PTGS2, SRC, TEK, TUBB3 |
2.48492 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.4832 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.4832 |
|
[BP] GO:0045907 |
None
|
EGFR, HTR2A, PTAFR, PTGS2 |
2.4832 |
|
[BP] GO:0051704 |
multi-organism process
|
APP, AXL, BCL2, CDK6, CHRM2, CYP1A1, DYRK1A, EGFR, HSD11B2, HSPA1A, HTR2A, IDO1, INSR, KDR, MET, MMP1, MMP12, MPO, POLA1, PRKCD, PTAFR, SMAD3, SRC, TOP1 |
2.48202 |
|
[BP] GO:0034762 |
None
|
ABCB1, APP, BCL2, CA2, DRD1, DRD2, GPR35, GRM5, KCNA3, MMP9, PRKCE, PTAFR |
2.47552 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.46811 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.46811 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.46811 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.46811 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
2.45945 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.45344 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
CA2, CA7, PRKCE |
2.45344 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR, MPO |
2.44706 |
|
[BP] GO:0072330 |
monocarboxylic acid biosynthetic process
|
ALOX15, CYP1A1, IDO1, MIF, PTGES, PTGS1, PTGS2 |
2.42583 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.42583 |
|
[BP] GO:0009266 |
None
|
ADORA1, HSPA1A, HTR1B, HTR2A, HTR2B, PTGS2, TRPV1 |
2.39012 |
|
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, PTGS2 |
2.38123 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.38123 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.38123 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, KDR, PRKCE, SMAD3, TEK |
2.36004 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.35766 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, PIK3CA, TNKS2 |
2.35719 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.35719 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
2.33408 |
|
[BP] GO:0048167 |
None
|
ADORA1, APP, DRD1, DRD2, GRM5, KIT, PTGS2 |
2.32628 |
|
[BP] GO:0003012 |
None
|
ADORA1, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
2.313 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.31299 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, PRKCE |
2.30306 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.30166 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GRM5, IGF1R, INSR, PRKCD, SRC |
2.30131 |
|
[BP] GO:0045321 |
leukocyte activation
|
ALOX5, AXL, BCL2, FLT3, FUT7, HSPA1A, KIT, MIF, MMP9, MPO, PRKCB, PRKCD, PRKCE, PTAFR, RORC, SMAD3, TRPV1 |
2.3 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AURKB, DNMT1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, PPARA, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.3 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, CNR1, HCAR2, HSPA1A, IDO1, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, SRC |
2.29952 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.29743 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.29743 |
|
[BP] GO:0009822 |
alkaloid catabolic process
|
CYP2D6, CYP3A4 |
2.29743 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.29743 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.29743 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.29743 |
|
[BP] GO:0031644 |
None
|
ADORA1, GPR35, GRM1, HTR2C, PTAFR |
2.28609 |
|
[BP] GO:1903524 |
None
|
EGFR, HTR2A, PTAFR, PTGS2, SLC1A1 |
2.28609 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
CYP1B1, DRD2, HSPA1A, HTR2B, IDO1, MIF, MMP12, PTAFR, PTGS2, SMAD3, SRC |
2.28609 |
|
[BP] GO:0050965 |
None
|
ADORA1, HTR2A, TRPV1 |
2.28609 |
|
[BP] GO:0050961 |
None
|
ADORA1, HTR2A, TRPV1 |
2.28609 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.28609 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, HTR2B, KDR, MMP12, PRKCA, SMAD3, TEK, XDH |
2.282 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.27832 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.27765 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
2.27765 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CYP1B1, F3, KDR, KIT, PRKCA, PRKCB, PTGS2, TEK, TERT, XDH |
2.27447 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, HMGCR, KIT |
2.26394 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, GBA2 |
2.26394 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AXL, BCL2, CBR1, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HTR2B, KDR, KIT, MET, MIF, MMP2, MMP9, PRKCD, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
2.2397 |
|
[BP] GO:0006936 |
None
|
DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
2.23945 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.23911 |
|
[BP] GO:0038128 |
None
|
EGFR, PIK3CA, PRKCA, SRC |
2.23911 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
2.23911 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
2.22809 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, INSR, PRKCE, TERT |
2.22122 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX15, CYP19A1, CYP3A4, HMGCR, PTAFR, TYR |
2.22122 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
2.22122 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
2.21414 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.21414 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.21414 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM4 |
2.21414 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.21414 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.21414 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, PTGS2 |
2.21414 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.21414 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, IDO1, PTGES, PTGS2, SMAD3, TERT, XDH |
2.19095 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DNMT1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.18622 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PRKCG, PTPN1, SRC |
2.18388 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, CNR1, CSNK2A1, DNMT1, DRD2, EGFR, ESR1, ESR2, GRIK5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PIK3CB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.17814 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, KDR, KIT, POLB, TEK, TYR |
2.15146 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
2.15146 |
|
[BP] GO:0046890 |
None
|
FABP3, HMGCR, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
2.15146 |
|
[BP] GO:0046903 |
None
|
ALOX5, APP, AXL, CA2, CA9, CHRM1, DRD2, HRH3, HSPA1A, KIT, MIF, MMP9, MPO, PRKCD, PTAFR, SLC1A1, SLC22A2, TRPV1, XDH |
2.14806 |
|
[BP] GO:0032412 |
None
|
ABCB1, APP, DRD2, GPR35, GRM5, MMP9, PRKCE, PTAFR |
2.14798 |
|
[BP] GO:0050865 |
regulation of cell activation
|
APP, AXL, BCL2, CNR1, CNR2, DUSP3, IDO1, MIF, PIK3CA, PRKCA, PRKCD, PTAFR, SRC |
2.14569 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.14224 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.14224 |
|
[BP] GO:1903034 |
regulation of response to wounding
|
F3, HMGCR, PRKCA, PRKCD, PRKCE, PTPRS, SMAD3 |
2.13992 |
|
[BP] GO:1903793 |
None
|
ABCB1, MIF, PRKCD, PTAFR |
2.1324 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, KIT, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.12959 |
|
[BP] GO:0031349 |
positive regulation of defense response
|
CNR1, EGFR, FABP4, HSPA1A, IDO1, MMP12, MMP2, PRKCD, PRKCE, PTGS2, SRC |
2.10533 |
|
[BP] GO:0050900 |
leukocyte migration
|
CNR2, FUT7, KIT, MIF, MMP1, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.09705 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, MAOA |
2.09652 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, MAOA |
2.09652 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.09652 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.08518 |
|
[BP] GO:0090257 |
None
|
ADORA1, CHRM1, CHRM2, KIT, PRKCA, PTAFR, PTGS2, SMAD3 |
2.08088 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, EGFR, HMGCR, KIT, POLB, PTGS2, TYR |
2.07696 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.07696 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.07696 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.07696 |
|
[BP] GO:0070542 |
None
|
FABP3, PRKCE, PTAFR, PTGS2, SRC |
2.05466 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, HTR5A, PTGS2 |
2.05189 |
|
[BP] GO:0050679 |
None
|
EGFR, F3, HTR2B, KDR, MMP12, PRKCA, TEK |
2.0505 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.0505 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.0505 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.0505 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.0505 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.0505 |
|
[BP] GO:1901529 |
None
|
ABCB1, PTAFR |
2.0505 |
|
[BP] GO:0014063 |
None
|
HRH3, HTR1B |
2.0505 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.0505 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.0505 |
|
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.0505 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.03608 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, BCL2, CSNK2A1, DRD2, EGFR, ESR2, HSPA1A, INSR, MPO, PIK3CA, PIM1, PTPRS, SMAD3, TNKS2 |
2.02927 |
|
[BP] GO:0016048 |
None
|
ADORA1, HTR2A, TRPV1 |
2.02041 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.02041 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.02041 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.02041 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.02041 |
|
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, EGFR, PRKCE, PTAFR, SRC |
2.01626 |
|
[BP] GO:0090342 |
None
|
CDK6, MIF, NUAK1, TERT |
2.00621 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, DRD1, DRD2, EGFR, ESR1, F10, F3, FLT3, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNA3, KDR, KIT, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TERT, TRPV1 |
14.7959 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CA4, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, F10, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HRH3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
14.2101 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ABCG2, ADORA1, ADORA3, ALOX15, APP, AXL, BACE1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, DUSP3, EGFR, F10, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HRH3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNA3, KDR, KIT, MET, PRKCG, PTAFR, PTGS2, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
13.1856 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HRH3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTAFR, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
12.7406 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALOX15, ALOX5, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
12.0084 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, PIK3CA, PIK3CB, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TBXAS1, TEK, TRPV1, TYR |
10.175 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ABCG2, ADORA1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, DRD1, DRD2, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, INSR, MET, PRKCG, PTGS2, SLC1A1, SLC22A1, SRC, TEK, TRPV1 |
8.40058 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, BACE1, CA2, CHRM1, CHRM2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, KCNA3, PRKCG, PTGS2, PTPRS, SRC, TUBB3 |
6.40156 |
|
[CC] GO:0031224 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALPL, APP, AXL, BACE1, CA12, CA14, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP3A4, DRD1, DRD2, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, PTAFR, PTGES, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TBXAS1, TEK, TRPV1, TYR |
6.2641 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, BACE1, CA2, CHRM1, CHRM2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HRH3, HTR2A, HTR2B, HTR5A, IDO1, INSR, KCNA3, PRKCG, PTGS1, PTGS2, PTPRS, SLC22A2, SRC, TOP1, TRPV1, TUBB3 |
6.18861 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CNR1, CNR2, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, KCNA3, PIK3CA, PRKCG, PTGS2, PTPRS, SRC, TEK, TUBB3 |
5.74753 |
|
[CC] GO:0016021 |
None
|
ABCB1, ABCG2, ADORA1, ADORA3, ALPL, APP, AXL, BACE1, CA12, CA14, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP3A4, DRD1, DRD2, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, PTAFR, PTGES, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TBXAS1, TEK, TRPV1, TYR |
5.64066 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CHRM1, CHRM2, CHRM4, CNR1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HRH3, PRKCG, PTPRS, SLC22A2, SRC, TRPV1 |
5.49287 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CNR1, CNR2, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, KCNA3, PIK3CA, PRKCG, PTGS2, PTPRS, SRC, TEK, TUBB3 |
5.25554 |
|
[CC] GO:0097060 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, TRPV1 |
4.84261 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, MIF, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.724 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, F10, FLT3, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGES, PTGS1, PTGS2, PTPN1, TBXAS1 |
4.34069 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGES, PTGS1, PTGS2, TBXAS1 |
3.69448 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CES2, CYP19A1, CYP2D6, FLT3, GBA2, GRIK5, HMGCR, HSPA1A, HTR5A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, XDH |
3.55758 |
|
[CC] GO:0042734 |
None
|
CNR1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
3.51849 |
|
[CC] GO:0045121 |
membrane raft
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KCNA3, KDR, PTGS2, SRC, TEK |
3.29585 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KCNA3, KDR, PTGS2, SRC, TEK |
3.27271 |
|
[CC] GO:0014069 |
None
|
ADORA1, CHRM1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
3.15807 |
|
[CC] GO:0099572 |
None
|
ADORA1, CHRM1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
3.15807 |
|
[CC] GO:0030424 |
None
|
APP, BACE1, CA2, CNR1, DRD2, GRM3, HTR2A, KCNA3, PTPRS, TUBB3 |
3.05878 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.05415 |
|
[CC] GO:0098793 |
None
|
ADORA1, APP, CHRM1, CHRM2, DRD2, GRIK5, HRH3, SLC22A2 |
2.89807 |
|
[CC] GO:0009330 |
None
|
TOP1, TOP2A |
2.7054 |
|
[CC] GO:0098589 |
membrane region
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KCNA3, KDR, PTGS2, SRC, TEK |
2.64486 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, APP, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA7, CBR1, CDC25B, CDK6, CES2, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA2, GRIA4, GRIK5, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR4, HTR5A, IDO1, INSR, KDR, KIT, MAOA, MIF, MMP2, MMP9, MPO, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
2.62676 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, PTGES, SRC, TNKS2, TYR |
2.53072 |
|
[CC] GO:0043235 |
receptor complex
|
ABCG2, APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
2.34686 |
|
[CC] GO:0045211 |
None
|
CHRM1, CHRM2, CHRM4, GRIA2, GRIA4, GRIK5, GRM3, TRPV1 |
2.27765 |
|
[CC] GO:0030425 |
None
|
CHRM1, CHRM2, CNR2, DRD2, GRIA2, GRIK5, GRM1, HTR5A, PRKCG, TUBB3 |
2.24468 |
|
[CC] GO:0043204 |
None
|
CNR2, DRD2, GRIK5, HTR5A, PTPRS, TOP1 |
2.20629 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.15146 |
|
[CC] GO:0044309 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.11895 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CNR1, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM3, HTR2A, INSR, PTGS1, SRC, TRPV1 |
2.09102 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CNR1, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM3, HTR2A, INSR, PTGS1, SRC, TRPV1 |
2.09102 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA6, CA9, CBR1, CDK6, CES2, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HMGCR, HSPA1A, HTR2A, HTR4, HTR5A, HTR6, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MIF, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP1, TOP2A, TUBB3, TYR, XDH |
2.03128 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM4, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
22.7081 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM4, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
20.3674 |
|
[MF] GO:0008227 |
None
|
CHRM1, CHRM2, CHRM4, DRD2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
18.9274 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ABCG2, ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TUBB3, TYR, XDH |
17.6424 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
17.3602 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PIM1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
15.7689 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
15.4761 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PTAFR, RORC, TEK, TRPV1 |
15.3343 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PPARA, PRKCE, PTAFR, RORC, SMAD3, TEK, TRPV1 |
15.1312 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.4717 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.4717 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK, TRPV1 |
14.3387 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, PTAFR, TEK, TRPV1 |
14.3387 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.3029 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.3029 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TUBB3, TYR, XDH |
13.9845 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ABCG2, ACHE, AURKB, AXL, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, DRD1, DRD2, DYRK1A, EGFR, FLT3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
13.0718 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, KIT, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
11.8687 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
10.7953 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, MAOA, MPO, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
10.5861 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
10.2175 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, IDO1, MPO, PTGS1, PTGS2, SRC, TBXAS1 |
9.78509 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, IDO1, MPO, PTGS1, PTGS2, SRC, TBXAS1 |
9.36594 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
9.03036 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD1, DRD2, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HRH3, HRH4, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, PTAFR |
8.83108 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HMGCR, HSD11B2, HSD17B1, IDO1, MPO, NQO2, POLA1, PTGES, PTGS1, PTGS2, SRC, TBXAS1, XDH |
8.76592 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
8.70566 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, TBXAS1, XDH |
7.55772 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, POLB |
7.55695 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA6, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
7.49217 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
7.48564 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1 |
7.22085 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.02698 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
6.98976 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, TBXAS1, TYR |
6.68823 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, TBXAS1, TYR |
6.62138 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, IDO1, KIT, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.49279 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1 |
6.48739 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TERT, TOP1 |
6.28259 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
6.19481 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
6.19045 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.0677 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.03951 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1 |
5.83395 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ABCG2, ALOX15, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, F10, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTPRS, SLC1A1, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3, XDH |
5.57989 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ABCG2, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MMP12, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP1, TOP2A, TRPV1, TUBB3, XDH |
5.57708 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
5.53139 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.29004 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ABCG2, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3, XDH |
5.27225 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.20069 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3, XDH |
5.11962 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3, XDH |
5.11697 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, GLO1, POLB |
5.0595 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ABCG2, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IDO1, IGF1R, INSR, KDR, KIT, MET, MMP12, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP1, TOP2A, TRPV1, TUBB3, XDH |
5.00514 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
4.94195 |
|
[MF] GO:0005496 |
steroid binding
|
CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
4.79914 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR, KIT |
4.64551 |
|
[MF] GO:0015238 |
None
|
ABCB1, ABCG2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.52654 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CES2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HRH3, HRH4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IDO1, IGF1R, INSR, KCNA3, KDR, KIT, MAOA, MET, MIF, MMP1, MMP12, MMP2, MMP9, MPO, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGES, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.3863 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
4.24923 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
4.05991 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.04424 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.04424 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.04409 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1 |
4.01408 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ABCG2, ADORA1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MPO, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPRS, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3 |
3.82808 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.82298 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, HMGCR, HSPA1A, KIT, MET, MIF, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.79265 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM4 |
3.69379 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
3.62569 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CDK6, CSNK2A1, DYRK1A, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, TOP1 |
3.50385 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.44556 |
|
[MF] GO:0004969 |
None
|
HRH3, HRH4, HTR6 |
3.44556 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, KIT, MET, MIF, MMP9, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
3.33939 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, PTAFR, RORC, TRPV1 |
3.33292 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, NQO2, XDH |
3.18424 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3 |
3.10072 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.8991 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
2.8991 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.8991 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
2.83531 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3 |
2.83412 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, NQO2 |
2.8189 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3 |
2.80517 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP1, TOP2A, TRPV1, TUBB3 |
2.79827 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.77675 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
2.77675 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.7054 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.7054 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.7054 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.7054 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.7054 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.7054 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.67731 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.65346 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.54668 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, BACE1, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SRC, TEK, TOP1 |
2.50165 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.38372 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.30166 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.29743 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.29743 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.29743 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.29743 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.29743 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.29743 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.29743 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.29743 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.29743 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.29743 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.19452 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.19224 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.14224 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ABCG2, ACHE, AOX1, BCL2, DRD2, FLT3, HMGCR, KIT, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TYR, XDH |
2.13444 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.13444 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM4 |
2.07696 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.06334 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.0505 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.0505 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.0505 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.0505 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.0505 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, POLA1, PRKCB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.02041 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.02041 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.02041 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.01626 |
