| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CHRM1, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, DRD3, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, INSR, KDR, KIT, MET, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS1, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
22.0651 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, GPER1, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, POLB, PPARA, PRKCB, PRKCD, PRKCE, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
17.4496 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
16.9131 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, ABCG2, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR3C1, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
16.3658 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, KIT, MET, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TRPV1 |
15.2705 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPER1, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.6128 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPER1, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.5825 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
13.3004 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPER1, GPR35, GRM1, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.0092 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, FLT3, GPER1, HSD11B2, NR3C1, PRKCE, PRKCG, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
11.9811 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, ALOX12, APP, AR, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, GPER1, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, NUAK1, PIM1, PRKCA, PTGES, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
11.6733 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.6346 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
11.4613 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.4439 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
11.4439 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.4439 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX12, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, GPER1, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
11.4439 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPER1, GPR35, GRM1, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MET, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
11.2245 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
11.1612 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, FABP3, FUT7, GBA2, GLO1, HMGCR, HSD17B3, HSPA1A, HTR2C, PIK3CA, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR, XDH |
11.1612 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.1396 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD2, DRD3, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, KIT, PRKCE, PTGS2 |
11.0343 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD2, DRD3, EGFR, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8, KIT, PRKCE, PTGS2 |
11.0343 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, GPER1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HTR1A, HTR2C, PRKCA, PRKCE, SLC22A1 |
10.5234 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GPER1, GRIK5, GRM1, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
10.513 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, GRM5, HSD11B2, IGF1R, INSR, KIT, MMP2, NR3C1, PPARA, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1 |
10.4841 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
10.4658 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, ABCG2, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DRD2, DRD3, EGFR, FABP3, HMGCR, HSD11B2, HTR2C, KDR, NR3C1, POLB, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TRPV1 |
10.4658 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, GPER1, GPR35, GRM1, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
10.4435 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.4435 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.4394 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GPER1, GRIK5, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
10.3871 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPER1, GPR35, GRM1, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MET, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.3871 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, AKR1B1, ALOX12, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, FLT3, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2C, INSR, MET, PIK3CA, PIK3CB, POLA1, POLB, PRKCB, PRKCE, SMAD3, SRC, TERT, TRPV1 |
10.3255 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX12, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
10.2215 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CHRM1, CHRM4, CYP19A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
10.1311 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, KIT, MET, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
10.0468 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD11B2, INSR, KIT, NR3C1, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK, TRPV1 |
9.98991 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.96427 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GPER1, HSD11B2, HSD17B2, NR3C1, PRKCE, PTGES, PTGS2, RORC, SRC, TYR |
9.95922 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TERT, TRPV1 |
9.94829 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DNMT1, EGFR, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM5, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
9.63028 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HMGCR, HTR2C, KDR, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
9.48009 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, ALOX12, AR, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, GPER1, HMGCR, HTR1A, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, PIM1, PRKCA, PTGS2, TEK, TERT |
9.47869 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
9.41735 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.32869 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.23068 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2, TBXAS1 |
9.07912 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A |
8.96955 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.9272 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, KIT, MMP9, PRKCD, PTGES, PTGS2, SRC, TERT |
8.85096 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, AKR1B1, ALOX12, APP, BCL2, CA12, CA2, CA7, CNR1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2C, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.84493 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CDK6, CYP1B1, DNMT1, EGFR, ESR1, GPER1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TRPV1 |
8.79581 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, KIT, MET, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.78483 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.77526 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, APP, AR, AXL, BCL2, CHRM1, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GPER1, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HSD17B2, HTR1A, HTR2C, IGF1R, INSR, KIT, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
8.76378 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
8.76378 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.75084 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD2, DRD3, EGFR, FABP3, FLT3, GPER1, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
8.74047 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, FABP3, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2C, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.72108 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, FABP3, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2C, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.72108 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
8.69473 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, GRM8, HMGCR, HTR2C, IGF1R, INSR, KDR, KIT, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.69473 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.62088 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, GRM8, HMGCR, HTR2C, IGF1R, INSR, KDR, KIT, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.60348 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, GPER1, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
8.49989 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CYP19A1, DRD2, DRD3, EGFR, GPER1, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, INSR, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
8.47281 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2C, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.458 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.39794 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPI, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
8.38186 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, ALOX12, APP, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, GPER1, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
8.29193 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPER1, GPR35, GRM3, GRM8, HMGCR, HSPA1A, HTR2C, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.26705 |
|
[BP] GO:0007187 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1A |
8.26452 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DNMT1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.2603 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2C, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.20735 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DRD2, EGFR, FLT3, GPER1, GRM1, HMGCR, HTR2C, INSR, KDR, KIT, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
8.17972 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.16173 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD2, DRD3, EGFR, FABP3, FLT3, GPER1, GRM5, HSD11B2, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
8.11594 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ALOX12, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.06189 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, DRD3, FABP3, FLT3, GPER1, HCAR2, HMGCR, HTR2C, KIT, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
8.06005 |
|
[BP] GO:0007188 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, DRD2, DRD3, GPER1, GRM1, GRM3, GRM5, GRM8, HTR1A |
8.05252 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.97816 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPI, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
7.83506 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DRD2, DUSP3, EGFR, FLT3, GPER1, GRM1, HMGCR, HTR2C, IGF1R, INSR, KDR, KIT, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
7.83063 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
7.82724 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DNMT1, EGFR, ESR1, FABP4, FLT3, GPER1, GRIK5, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, POLA1, POLB, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
7.80385 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, ALOX12, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
7.77785 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ALOX12, APP, BCL2, EGFR, F10, F3, GPER1, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.7358 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
7.70148 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
7.54892 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPER1, GPR35, GRM1, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
7.54892 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.54809 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD2, DRD3, EGFR, GPER1, GRIK5, HTR1A, INSR, PTGS2, SLC1A1, SLC22A2, SLC22A3, SMAD3, TRPV1 |
7.48014 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
7.45249 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPER1, GPR35, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, HTR2C, IGF1R, KDR, KIT, MET, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.33649 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.24314 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2C, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.23406 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.23183 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GPER1, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2C, INSR, KDR, KIT, MET, MMP12, MMP9, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
7.16913 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.10879 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD2, DRD3, EGFR, GRM1, HMGCR, HSD11B2, HSPA1A, KIT, MMP2, POLB, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
7.06035 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
7.00908 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD2, DRD3, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GPER1, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KIT, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
7.00214 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX12, ALOX15, AR, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPER1, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, XDH |
6.99255 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
6.98615 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, PIM1, PRKCG, SRC, TEK |
6.94756 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX12, ALOX15, ALPI, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2 |
6.88859 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2C, IGF1R, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.8775 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, FABP4, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
6.84471 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, POLB, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.77122 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CHRM4, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
6.71544 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
6.71544 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPER1, GPR35, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KIT, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
6.71544 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, GPER1, HCAR2, HMGCR, HSPA1A, KDR, KIT, MET, MMP12, MMP9, PIM1, PRKCA, PRKCB, PRKCE, PTGS2, SLC1A1, SMAD3, SRC, TEK, TERT, TRPV1 |
6.68336 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2, DRD2, PRKCE |
6.6662 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD2, DRD3, HMGCR, KDR, POLB, PRKCD, PRKCE, SRC |
6.61692 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPER1, GPR35, GRM1, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
6.60942 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GPER1, GRM1, GRM5, HMGCR, HTR2C, IGF1R, INSR, KDR, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.59397 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.50188 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, ALOX12, CNR1, CNR2, CYP19A1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, GPER1, HMGCR, KDR, MET, MMP12, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, SMAD3, TEK |
6.48486 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX12, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, DRD3, GBA2, HMGCR, HSD17B3, HTR1A, TYR |
6.44498 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AR, AURKB, BCL2, CHRM1, CHRM4, CYP1A1, EGFR, ESR1, FLT3, HTR1A, KIT, MET, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TYR |
6.44498 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.44158 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, FABP4, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
6.38136 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
6.35531 |
|
[BP] GO:0032787 |
None
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1 |
6.3408 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, DRD2, DRD3, EGFR, ESR1, FABP3, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.29179 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
6.27504 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.26209 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.25764 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.23358 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGES, PTGS1, PTGS2, TBXAS1 |
6.16229 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.16229 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, DNMT1, EGFR, ESR1, FLT3, GPER1, GRM5, IGF1R, INSR, KIT, MMP2, NR3C1, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
6.15353 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
6.11278 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
6.05791 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, DYRK1A, EGFR, ESR1, KIT, PPARA, PRKCG, RORC, SRC, TOP2A |
6.04678 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2C, KIT, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
5.90867 |
|
[BP] GO:0006855 |
None
|
ABCB1, ABCG2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
5.89894 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
5.89894 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, APP, BCL2, CA12, CA2, CA7, DRD2, DRD3, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.8861 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, DRD2, DRD3, EGFR, GPER1, GPR35, GRM1, HCAR2, HTR2C, KIT, PRKCA, PTGS2, SLC1A1, SMAD3, TRPV1 |
5.84311 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, APEX1, APP, BCL2, CA2, CA7, DRD2, DRD3, ESR1, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2C, PIK3CA, PIK3CB, POLA1, PRKCB, PRKCE, SMAD3, TRPV1 |
5.81423 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GPER1, GRM5, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
5.81423 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2C, KIT, PRKCD, SRC, TEK |
5.80592 |
|
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2C, PRKCG, SLC1A1 |
5.79078 |
|
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2C, PRKCG, SLC1A1 |
5.79078 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, GPER1, NR3C1, PTGS2, RORC, SRC, TRPV1 |
5.79 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD2, DRD3, ESR1, GPER1, GPR35, GRIK5, GRM1, GRM5, HTR2C, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.78325 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DNMT1, DRD2, DRD3, ESR1, GPER1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
5.77489 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
5.74508 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD2, DRD3, GPER1, HTR2C, KDR, PRKCE, SRC, TRPV1 |
5.74313 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PPARA, RORC, SRC |
5.71215 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
5.69096 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, PIK3CA, POLB, PPARA, SMAD3, SRC, TEK, TYR |
5.67264 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, DRD2, DRD3, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.63151 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD2, DRD3, EGFR, GRM1, GRM5, HMGCR, HTR1A, HTR2C, INSR, KIT, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
5.61607 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPER1, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
5.57305 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPER1, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
5.54844 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
ALOX12, CYP1B1, F3, GPER1, KDR, KIT, PRKCA, PRKCB, PTGS2, TEK, TERT |
5.54063 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PIM1, PPARA, RORC, SRC |
5.54063 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, GPER1, INSR, PRKCA, PRKCE, SRC, TERT |
5.50461 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, KIT, MMP9, PTGES, PTGS2, TERT |
5.4757 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, APP, AR, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, INSR, KIT, MET, MMP9, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.45303 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CHRM1, CNR1, DRD2, DRD3, EGFR, GRM5, HMGCR, INSR, KIT, PRKCG, PTGS2 |
5.40943 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, DUSP3, EGFR, GPER1, HMGCR, HTR2C, KDR, PRKCA, PTPN1, SRC, TEK |
5.37604 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD2, DRD3, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.36655 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, DRD2, DRD3, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.36655 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPI, ALPL, AOX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, CYP3A4, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.35159 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2, HSD17B3 |
5.331 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, HTR2C, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
5.32982 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD2, DRD3, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.32853 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, GPER1, HSD11B2, HSPA1A, HTR1A, HTR2C, KIT, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
5.31601 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.27104 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, EGFR, KDR, NR3C1, PRKCD, PRKCE, PTGS2, SRC, TRPV1 |
5.24902 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, DRD2, DRD3, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.20945 |
|
[BP] GO:0008217 |
None
|
ADORA1, AR, CNR1, DRD2, DRD3, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
5.20436 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.20199 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.20199 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, APP, BCL2, CA2, CA7, DRD2, DRD3, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.18797 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DRD3, DUSP3, DYRK1A, ESR1, GPER1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
5.18109 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, NQO2, PTGS1, RORC |
5.15463 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, DRD2, DRD3, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
5.15266 |
|
[BP] GO:0007154 |
None
|
ADORA1, AR, AXL, BCL2, CHRM1, CHRM2, CHRM4, CNR1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2C, PRKCG, PTGS2, SLC1A1, TEK, TRPV1 |
5.13705 |
|
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM4, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2C, PRKCG, SLC1A1 |
5.10022 |
|
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM4, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2C, PRKCG, SLC1A1 |
5.10022 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, EGFR, GPER1, HMGCR, HTR2C, KDR, PRKCA, SRC, TEK |
5.07405 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DYRK1A, EGFR, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP2A |
5.07178 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, DRD2, DRD3, EGFR, GPER1, HCAR2, INSR, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TERT, TRPV1 |
5.00441 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CHRM1, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HMGCR, HTR2C, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.99792 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD2, EGFR, GPER1, PRKCE, PTGS2 |
4.95536 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.94235 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.9395 |
|
[BP] GO:0006811 |
None
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, GRIA2, GRIA4, GRIK5, HTR2C, PPARA, PRKCB, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
4.93691 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, APP, BCL2, CA2, CA7, CHRM1, CNR1, DRD2, DRD3, GPER1, GPR35, GRM5, HTR1A, MMP9, PRKCD, PRKCE, PTGS2 |
4.92009 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.91945 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, APP, BCL2, DRD2, DRD3, EGFR, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.8925 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX12, ALOX15, ALOX5, PTGES, PTGS1, PTGS2 |
4.86553 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, APP, BCL2, DRD2, DRD3, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.84392 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
4.83864 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
4.82088 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PPARA, RORC, SRC |
4.79472 |
|
[BP] GO:0007267 |
None
|
ADORA1, AR, CHRM1, CHRM2, CHRM4, CNR1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2C, PRKCG, SLC1A1, TEK |
4.75137 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CNR1, CYP19A1, DRD2, EGFR, GPER1, HCAR2, HMGCR, HTR1A, HTR2C, PRKCA, PRKCE |
4.74888 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.71586 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.71559 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, GPER1, MMP12, PPARA, PRKCD, SMAD3, TEK |
4.71348 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.7002 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, NR3C1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.69713 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, GPER1, HCAR2, HSPA1A, KIT, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
4.66368 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, GPER1, HSD11B2, NR3C1, PTGS2, SRC |
4.66319 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, GPER1, HSPA1A, MMP12, MMP2, PPARA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.60348 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.54124 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5 |
4.51015 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, ALOX12, CNR2, CYP19A1, DRD2, DRD3, GPER1, HMGCR, PPARA, PRKCD, SMAD3, TEK |
4.49621 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, EGFR, GPER1, GRM5, IGF1R, INSR, MMP2, PRKCD, PTGS2, SRC, TRPV1 |
4.45975 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TERT, TNKS, TOP2A |
4.45388 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, APP, BCL2, CHRM1, CNR1, CNR2, CYP1B1, DRD2, DRD3, EGFR, GPER1, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HTR1A, INSR, KIT, PIK3CA, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
4.44775 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD2, DRD3, GPR35, MMP9, PRKCE, PTGS2 |
4.44382 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
4.44208 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, KIT, PIK3CB, PRKCD, PTPN1, SRC |
4.41587 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CNR1, CNR2, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
4.40337 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2C, KIT, PRKCD, SRC, TEK |
4.38995 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD2, DRD3, EGFR, GRM5, HMGCR, INSR, KIT, PRKCG, PTGS2 |
4.38097 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
4.37874 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, PRKCA, TERT |
4.37694 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.31075 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.30621 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.30307 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.29018 |
|
[BP] GO:0015893 |
None
|
ABCB1, ABCG2, CA2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.28393 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GPER1, GRM1, GRM5, HSPA1A, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
4.25877 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2, TERT |
4.2443 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
4.23863 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
4.23205 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, DRD3, GPER1, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.22348 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, GPER1, HSPA1A, INSR, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TERT, TNKS, TOP2A |
4.2065 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
4.17966 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
ALOX12, CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
4.15751 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
ALOX12, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, GPER1, HMGCR, HTR2C, INSR, KDR, KIT, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT |
4.15669 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.1422 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, GPER1, HSD11B2, NR3C1, PTGS2, SRC |
4.14086 |
|
[BP] GO:0003018 |
None
|
ADORA1, CHRM1, EGFR, GPER1, HMGCR, HTR1A, PTGS2, SRC, TEK |
4.14086 |
|
[BP] GO:0023052 |
None
|
ADORA1, AR, CHRM1, CHRM2, CHRM4, CNR1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR2C, PRKCG, SLC1A1, TEK |
4.14086 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, GPER1, PPARA, PRKCD, SMAD3, TEK |
4.12444 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX12, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DNMT1, DRD2, DRD3, EGFR, ESR1, ESR2, GPER1, GRIK5, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PIK3CB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
4.11855 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.10969 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
AR, BCL2, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPER1, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT, XDH |
4.10842 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, EGFR, GPER1, GRM5, IGF1R, INSR, MMP2, PRKCD, PTGS2, SRC, TRPV1 |
4.09977 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.09862 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
4.07887 |
|
[BP] GO:0010676 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, SRC |
4.06159 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA, PRKCD, PRKCE |
4.06159 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX12, ALOX15, PTGES, PTGS1, PTGS2 |
4.05565 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CHRM1, CNR1, CSNK2A1, DRD2, DRD3, EGFR, GPER1, HCAR2, HMGCR, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
4.03332 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, GPER1, KIT, PIK3CA, PIK3CB, POLB, PTGES, PTGS1, PTGS2, TRPV1 |
4.03014 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.02438 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, APP, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, ESR1, GPER1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, INSR, PIK3CA, PIK3CB, SRC |
4.02438 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CDK6, CHRM1, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, HSD17B3, INSR, KDR, KIT, MMP9, PIK3CA, PIM1, POLB, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
4.01945 |
|
[BP] GO:0050793 |
regulation of developmental process
|
ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GPER1, HMGCR, HTR2C, INSR, KDR, KIT, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
3.97505 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
3.9613 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, KIT, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, RORC, SMAD3, SRC, TRPV1 |
3.9458 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.93492 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
3.92506 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
3.90689 |
|
[BP] GO:0007200 |
None
|
CHRM1, CHRM2, CHRM4, DRD2, ESR1, GRM5, HTR2C |
3.89922 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, HMGCR |
3.88569 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
3.88569 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, DRD3, EGFR, GPER1, GRIK5, HCAR2, HMGCR, HTR1A, HTR2C, MMP12, PRKCA, PRKCE, SRC, TRPV1 |
3.8696 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
3.86781 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, GPER1, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.86083 |
|
[BP] GO:0043278 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
3.86083 |
|
[BP] GO:0014072 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
3.86083 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HMGCR, HTR2C, MMP12, PRKCA, PRKCE, SRC |
3.86083 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, GPER1, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.85977 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.84597 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, GPER1, HMGCR, MMP2, MMP9, PTGS2, TERT |
3.82186 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
ALOX12, CYP1B1, F3, GPER1, KDR, KIT, PRKCA, PRKCB, PTGS2, TEK, TERT, XDH |
3.81953 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
3.81832 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX12, ALOX15, BCL2, CDK6, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, SMAD3, SRC, TEK |
3.79694 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CHRM1, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HMGCR, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.78293 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GPER1, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.78293 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DRD2, DRD3, EGFR, HSPA1A |
3.78293 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
3.78293 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, DNMT1, DRD2, DRD3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, GPER1, GRM3, GRM8, HSPA1A, MMP12, NR3C1, PPARA, PRKCA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
3.76488 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, GPER1, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
3.76488 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.76203 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM4 |
3.7593 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DNMT1, DRD2, DRD3, EGFR, GPER1, GRM5, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
3.7521 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, DNMT1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSPA1A, IGF1R, INSR, MET, MMP12, NR3C1, PPARA, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
3.74069 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, ALOX12, CHRM1, DRD2, F10, F3, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
3.74051 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX12, ALOX15, ALOX5, PTGS2 |
3.71008 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, DRD3, EGFR, GPER1, GRIK5, HCAR2, HMGCR, HTR1A, HTR2C, MMP12, PRKCA, PRKCE, SRC |
3.70417 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, EGFR, PPARA, SMAD3 |
3.69714 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TERT, TNKS |
3.68524 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, AR, EGFR, ESR1, FLT3, GPER1, INSR, KIT, NR3C1, PRKCD, PRKCE, SRC |
3.68524 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
3.6834 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, KIT, PRKCD, PRKCE, PTPN1, SRC |
3.66893 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, POLB, PRKCD, PTGS2, TERT |
3.66893 |
|
[BP] GO:0007612 |
None
|
APP, DRD2, DRD3, GRM5, HMGCR, INSR, KIT, PTGS2 |
3.65553 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
3.61181 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, PRKCG, RORC, TOP2A |
3.60168 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
3.57773 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM1, CHRM2, GPER1, KIT, PTGS2 |
3.55624 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
3.53677 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CHRM1, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HMGCR, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.53017 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX12, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, PTGS1, PTGS2, TBXAS1, TYR |
3.50563 |
|
[BP] GO:0032409 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCD, PRKCE |
3.50234 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM4 |
3.49218 |
|
[BP] GO:2001300 |
lipoxin metabolic process
|
ALOX12, ALOX15, ALOX5 |
3.49218 |
|
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.49218 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
3.49105 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.48752 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.47436 |
|
[BP] GO:0045913 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, SRC |
3.45658 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD2, DRD3, EGFR, NR3C1, PRKCE, PRKCG |
3.44919 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
3.44249 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, GPER1, HSPA1A, INSR, PRKCE, TERT, TNKS |
3.43331 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR, HSD17B3 |
3.42377 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, DYRK1A, EGFR, HMGCR, HSPA1A, IGF1R, MET, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, TERT, XDH |
3.38112 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.37689 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.37689 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR |
3.37547 |
|
[BP] GO:1900543 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA, PRKCA |
3.35766 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.35195 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CHRM1, CNR1, CNR2, CYP1B1, DRD2, DRD3, EGFR, GRM1, GRM5, GRM8, HMGCR, INSR, KIT, PRKCG, PTGS2, TRPV1, TYR |
3.34232 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, DRD3, PPARA |
3.33051 |
|
[BP] GO:0045980 |
None
|
DRD2, DRD3, GRM3, GRM8, PPARA, PRKCA |
3.32751 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, GRM1, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.32017 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, GPER1, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
3.32017 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.29697 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, CHRM1, DRD2, EGFR, GPER1, HCAR2, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.2885 |
|
[BP] GO:0009820 |
alkaloid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.27781 |
|
[BP] GO:0003013 |
None
|
ADORA1, CHRM1, EGFR, GPER1, HMGCR, HTR1A, PTGS2, SRC, TEK |
3.27147 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC, TERT |
3.27147 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, GPER1, NR3C1, SRC |
3.26761 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, GPER1, HCAR2, MMP12, PRKCE, SRC, TRPV1 |
3.26334 |
|
[BP] GO:0030818 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.24149 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTGES, PTGS2, SRC |
3.22844 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GPER1, GRM5, IGF1R, INSR, PRKCD, SRC |
3.22611 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
3.22611 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.21698 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, GPER1, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.20319 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GPER1, GRM1, GRM5, HMGCR, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.20319 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, HSD17B3, INSR, KIT, PTGS2, SRC |
3.19611 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, RORC |
3.19288 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.17969 |
|
[BP] GO:0030803 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.1566 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX12, ALOX15, CYP19A1, CYP3A4, HMGCR, HSD17B3, TYR |
3.1566 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, GPER1, NR3C1, SRC |
3.15127 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD2, DRD3, HTR1A, TYR |
3.15127 |
|
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, HSD17B3, INSR, KIT, SRC |
3.13921 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, ALOX12, DRD2, MET, PIK3CA, TRPV1 |
3.1299 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.11647 |
|
[BP] GO:1901570 |
None
|
ALOX12, ALOX15, ALOX5, PTGES, PTGS1, PTGS2 |
3.09472 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, PRKCE, TERT |
3.09091 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.09007 |
|
[BP] GO:0008542 |
None
|
APP, DRD2, DRD3, HMGCR, KIT |
3.07877 |
|
[BP] GO:0030815 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.07877 |
|
[BP] GO:0010675 |
None
|
ESRRB, GPER1, INSR, PPARA, PRKCE, RORC, SRC |
3.07136 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, PRKCE, SRC |
3.07136 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, ALPI, CSNK2A1, DRD2, EGFR, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
3.05209 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.0499 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, GRM5, PRKCD |
3.04359 |
|
[BP] GO:1900372 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.04197 |
|
[BP] GO:0030809 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.04197 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, BCL2, CDK6, CYP1B1, DRD2, FABP3, GPER1, HSPA1A, PTGES, PTGS2, SMAD3, TERT, XDH |
3.01171 |
|
[BP] GO:0097746 |
None
|
ADORA1, CHRM1, EGFR, GPER1, HMGCR, HTR1A, PTGS2 |
3.01171 |
|
[BP] GO:0035296 |
None
|
ADORA1, CHRM1, EGFR, GPER1, HMGCR, HTR1A, PTGS2 |
3.01171 |
|
[BP] GO:0030800 |
None
|
DRD2, DRD3, GRM3, GRM8, PRKCA |
3.00416 |
|
[BP] GO:0048169 |
None
|
APP, DRD2, GRM5, KIT |
2.98583 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, CHRM1, DRD2, EGFR, GPER1, HCAR2, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
2.98576 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
ALOX12, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, GPER1, HMGCR, INSR, KDR, KIT, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
2.98576 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
DRD2, ESR1, GPER1, GPR35, GRM1, GRM5, HTR2C, PRKCE, SMAD3, TRPV1 |
2.96679 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD2, DRD3, EGFR, HMGCR, KIT, PTGS2, TYR |
2.96679 |
|
[BP] GO:0022898 |
None
|
ABCB1, APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE |
2.9551 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.93038 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
2.92744 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CHRM1, CSNK2A1, DRD2, DRD3, EGFR, GPER1, GRIK5, HMGCR, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.91386 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, PRKCE, SRC |
2.90283 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC, TERT |
2.89584 |
|
[BP] GO:0007632 |
None
|
APP, DRD2, DRD3, HMGCR, KIT |
2.89584 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, CDK6, EGFR, ESR1, FLT3, GPER1, NR3C1, PRKCE, RORC, SRC |
2.88057 |
|
[BP] GO:1900542 |
None
|
DRD2, DRD3, ESRRB, GPER1, GRM3, GRM8, INSR, PPARA, PRKCA |
2.87576 |
|
[BP] GO:0050708 |
None
|
ACHE, CNR1, DRD2, DRD3, EGFR, GPER1, HCAR2, HMGCR, MMP12, PRKCA, PRKCE, SRC |
2.87468 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD2, DRD3, GPR35, HMGCR, HSPA1A, MMP9, PRKCB, PRKCE, PTGS2 |
2.86568 |
|
[BP] GO:0050880 |
None
|
ADORA1, CHRM1, EGFR, GPER1, HMGCR, HTR1A, PTGS2 |
2.85903 |
|
[BP] GO:0051588 |
None
|
DRD2, DRD3, GPER1, GRIK5, HTR1A, HTR2C |
2.84286 |
|
[BP] GO:0035150 |
None
|
ADORA1, CHRM1, EGFR, GPER1, HMGCR, HTR1A, PTGS2 |
2.83973 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DNMT1, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, GPER1, HMGCR, HSPA1A, IGF1R, KDR, MMP12, MMP9, NR3C1, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.82823 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.81927 |
|
[BP] GO:0043279 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG, TRPV1 |
2.81927 |
|
[BP] GO:0040008 |
regulation of growth
|
ALOX12, APP, AR, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HSPA1A, INSR, PIK3CA, PIM1, SMAD3, TNKS2 |
2.81927 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, PRKCA, PRKCB, PRKCD |
2.81163 |
|
[BP] GO:0008209 |
androgen metabolic process
|
CYP19A1, CYP3A4, ESR1, HSD17B3 |
2.81163 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, KIT, PIK3CB, PRKCD, PTPN1, SRC |
2.81163 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, HSD17B3, INSR, KIT, MMP2, MMP9, PTGS2, SRC, TOP2A |
2.80799 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
2.80799 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, KIT, MMP9, TERT |
2.79447 |
|
[BP] GO:0006140 |
None
|
DRD2, DRD3, ESRRB, GPER1, GRM3, GRM8, INSR, PPARA, PRKCA |
2.79145 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.77915 |
|
[BP] GO:0072347 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
2.76208 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.76208 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPI, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.75331 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.75129 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX12, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, HMGCR, HSD17B3, PTGES, PTGS1, PTGS2 |
2.74897 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTGS2 |
2.73427 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.73031 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.73031 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.73031 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.73031 |
|
[BP] GO:2001301 |
lipoxin biosynthetic process
|
ALOX12, ALOX15 |
2.73031 |
|
[BP] GO:2001302 |
lipoxin A4 metabolic process
|
ALOX12, ALOX15 |
2.73031 |
|
[BP] GO:2001303 |
lipoxin A4 biosynthetic process
|
ALOX12, ALOX15 |
2.73031 |
|
[BP] GO:0035265 |
organ growth
|
AR, BCL2, CYP19A1, ESR1 |
2.71379 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.71379 |
|
[BP] GO:0045936 |
None
|
DRD2, DRD3, DUSP3, FABP4, GPER1, GRM3, GRM8, HMGCR, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
2.71357 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.71357 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.71357 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.71032 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6, CYP3A4 |
2.71032 |
|
[BP] GO:0010563 |
None
|
DRD2, DRD3, DUSP3, FABP4, GPER1, GRM3, GRM8, HMGCR, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
2.71032 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, TRPV1, TYR |
2.69798 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, FLT3, GPER1, KDR, KIT, TEK |
2.69692 |
|
[BP] GO:0061041 |
regulation of wound healing
|
ALOX12, F3, HMGCR, PRKCA, PRKCD, PRKCE, SMAD3 |
2.67643 |
|
[BP] GO:0030817 |
None
|
DRD2, DRD3, GPER1, GRM3, GRM8, PRKCA |
2.67348 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, GPER1, HSPA1A, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.65915 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.64536 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, GPER1, HCAR2, MMP12, PRKCE, SRC |
2.63205 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, HMGCR, HSD11B2, KIT, MMP12, PRKCD, PTGES, PTGS2, SMAD3, SRC, TRPV1, TYR |
2.62933 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.62817 |
|
[BP] GO:0007194 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.61409 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, AR, BCL2, CHRM1, CSNK2A1, EGFR, GPER1, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.6105 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.6068 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.6068 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.6068 |
|
[BP] GO:0015872 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.6068 |
|
[BP] GO:0070989 |
oxidative demethylation
|
CYP1A2, CYP2D6, CYP3A4 |
2.6068 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPI, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.60126 |
|
[BP] GO:0036211 |
protein modification process
|
ALPI, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.60126 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.5953 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
ALOX12, BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.59072 |
|
[BP] GO:0051234 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, DRD2, DRD3, EGFR, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR2C, KIT, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TERT, TNKS, TRPV1, XDH |
2.58757 |
|
[BP] GO:0090276 |
None
|
CNR1, DRD2, EGFR, GPER1, HMGCR, HTR2C, PRKCA, PRKCE |
2.57843 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.57461 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.57461 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA3, ALOX15, APP, AXL, BCL2, CNR2, GPER1, HTR1A, HTR2C, KIT, PIK3CA, PIK3CB, POLB, PRKCD, PTGES, PTGS1, PTGS2, SRC, TRPV1 |
2.57461 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD2, PTGS2 |
2.56461 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, DRD3, HTR1A |
2.56461 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPI, ALPL, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.56461 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, PPARA, RORC |
2.53898 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, KIT, PIK3CB, PTPN1, SRC |
2.53746 |
|
[BP] GO:0031280 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.52762 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, GPER1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.52726 |
|
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, F3, KDR, MMP12, PRKCA, SMAD3, TEK, XDH |
2.51434 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.51424 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
CA2, CA7, PRKCE |
2.51424 |
|
[BP] GO:0001516 |
None
|
PTGES, PTGS1, PTGS2 |
2.51424 |
|
[BP] GO:0046457 |
None
|
PTGES, PTGS1, PTGS2 |
2.51424 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, KDR, PRKCE, SMAD3, TEK |
2.51317 |
|
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
FLT3, GPER1, KDR, KIT, TEK |
2.51052 |
|
[BP] GO:1903829 |
positive regulation of cellular protein localization
|
APP, BCL2, CHRM1, EGFR, GPER1, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TERT |
2.50218 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.48066 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, GBA2 |
2.47424 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC, TERT |
2.4659 |
|
[BP] GO:0006650 |
glycerophospholipid metabolic process
|
ACHE, ALOX15, ALPI, CSNK2A1, DRD2, EGFR, KIT, MET, PIK3CA, PIK3CB |
2.46096 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
2.46033 |
|
[BP] GO:0032465 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.45576 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CNR1, CNR2, CSNK2A1, DRD2, DRD3, DUSP3, FABP4, GRM3, HMGCR, IGF1R, MMP9, PRKCA, PRKCD, PTGS2, PTPN1, SRC |
2.45347 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, GPER1, MMP12 |
2.45307 |
|
[BP] GO:0051350 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.4461 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
2.4461 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.42981 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.42644 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
2.41733 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX12, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.40224 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, PTGS2, SRC |
2.40155 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, KIT, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.39794 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, KDR, MET, PRKCA, PTGS2, SMAD3 |
2.37935 |
|
[BP] GO:0008306 |
None
|
APP, DRD2, DRD3, HMGCR, KIT |
2.37565 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, GPER1, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PPARA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.37517 |
|
[BP] GO:0051179 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, DRD2, DRD3, EGFR, ESR1, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR2C, KIT, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.37306 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PRKCG, PTPN1, SRC |
2.36772 |
|
[BP] GO:0048806 |
genitalia development
|
AXL, CYP19A1, ESR1, HSD17B3 |
2.36355 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.36355 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.35244 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.35143 |
|
[BP] GO:0051937 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.34387 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.34387 |
|
[BP] GO:0032412 |
None
|
ABCB1, APP, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE |
2.33962 |
|
[BP] GO:0030814 |
None
|
DRD2, DRD3, GPER1, GRM3, GRM8, PRKCA |
2.33962 |
|
[BP] GO:0038128 |
None
|
EGFR, PIK3CA, PRKCA, SRC |
2.33962 |
|
[BP] GO:0097756 |
None
|
ADORA1, HMGCR, HTR1A, PTGS2 |
2.33962 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
GPER1, MMP2, MMP9, TERT |
2.33962 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.33962 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.33962 |
|
[BP] GO:0009822 |
alkaloid catabolic process
|
CYP2D6, CYP3A4 |
2.33962 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.33962 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.33962 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.33962 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.33962 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD2, DRD3, EGFR, HMGCR, KIT, POLB, PTGS2, TYR |
2.33938 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, KDR, KIT, POLB, TEK, TYR |
2.32923 |
|
[BP] GO:1903034 |
regulation of response to wounding
|
ALOX12, F3, HMGCR, PRKCA, PRKCD, PRKCE, SMAD3 |
2.31451 |
|
[BP] GO:0032413 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.29314 |
|
[BP] GO:0050866 |
negative regulation of cell activation
|
ALOX12, AXL, CNR1, CNR2, DUSP3, GPER1, PRKCD |
2.28606 |
|
[BP] GO:0030802 |
None
|
DRD2, DRD3, GPER1, GRM3, GRM8, PRKCA |
2.286 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.2839 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.2839 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM4 |
2.2839 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.2839 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.2839 |
|
[BP] GO:0032225 |
None
|
DRD2, DRD3, PTGS2 |
2.2839 |
|
[BP] GO:0090257 |
None
|
ADORA1, CHRM1, CHRM2, GPER1, KIT, PRKCA, PTGS2, SMAD3 |
2.28184 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD2, EGFR, FUT7, KDR, KIT, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
2.27452 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPI, ALPL, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CDK6, CHRM1, CSNK2A1, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUT7, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.26521 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.2633 |
|
[BP] GO:0033043 |
regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, DRD3, GPER1, GRIK5, HSPA1A, INSR, KDR, MET, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.2484 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GPER1, INSR, PPARA, PRKCE, RORC, SRC |
2.23496 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, PTGS2, SRC |
2.23031 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DRD2, DUSP3, ESR1, HSPA1A, KIT, MMP12, MMP2, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
2.23031 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, F3, KDR, MMP12, PRKCA, TEK |
2.22159 |
|
[BP] GO:0045765 |
regulation of angiogenesis
|
ALOX12, CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
2.22133 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.21285 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.21285 |
|
[BP] GO:0034762 |
None
|
ABCB1, APP, BCL2, CA2, DRD2, DRD3, GPER1, GPR35, GRM5, MMP9, PRKCE |
2.21213 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, GPER1, PTGS2 |
2.20477 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, GPER1, HCAR2, MMP12, PRKCE, SRC |
2.20455 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.19696 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, GPER1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.19328 |
|
[BP] GO:0090066 |
None
|
ADORA1, ALOX15, CHRM1, EGFR, GPER1, HMGCR, HTR1A, PRKCD, PRKCE, PTGS2 |
2.19161 |
|
[BP] GO:0046887 |
positive regulation of hormone secretion
|
CYP19A1, DRD2, EGFR, GPER1, HCAR2, PRKCE |
2.18899 |
|
[BP] GO:0006810 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, DRD2, DRD3, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR2C, KIT, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
2.18312 |
|
[BP] GO:1903076 |
None
|
AR, CSNK2A1, EGFR, GPER1, PRKCE |
2.18312 |
|
[BP] GO:0007626 |
None
|
APP, DRD2, DRD3, GRM1, GRM5, HTR2C, PRKCE |
2.17033 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, TERT |
2.16293 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.14602 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.14602 |
|
[BP] GO:0090330 |
regulation of platelet aggregation
|
ALOX12, PRKCA, PRKCD |
2.14602 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.13848 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.13848 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, FABP3, FABP4, FUT7, GBA2, HSPA1A, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
2.13247 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD2, DRD3, HTR1A |
2.13247 |
|
[BP] GO:0045761 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.13231 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2C, PRKCE, TRPV1 |
2.13231 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.13231 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2C, PRKCE, TRPV1 |
2.13231 |
|
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CDK6, CNR1, DRD2, DRD3, EGFR, ESRRA, ESRRB, GPER1, HTR2C, KDR, KIT, PPARA, PRKCA, PRKCB, PTGS2, RORC, SMAD3, TERT, TRPV1, XDH |
2.12853 |
|
[BP] GO:1900371 |
None
|
DRD2, DRD3, GPER1, GRM3, GRM8, PRKCA |
2.12673 |
|
[BP] GO:0030258 |
lipid modification
|
ALOX12, CYP1A1, CYP3A4, EGFR, KIT, MET, PIK3CA, PIK3CB |
2.12131 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, KIT, PRKCD, PTGS2 |
2.12131 |
|
[BP] GO:0032410 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.12131 |
|
[BP] GO:1904063 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.12131 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.1123 |
|
[BP] GO:0030808 |
None
|
DRD2, DRD3, GPER1, GRM3, GRM8, PRKCA |
2.1123 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.10076 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.10007 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.10007 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
APP, AR, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, TNKS2 |
2.09767 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
2.09752 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.09752 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.09752 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.09752 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.09752 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.09752 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.09752 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.09752 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.09752 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.09752 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.08997 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
DRD2, ESR1, GPER1, GPR35, GRM1, HTR2C, PRKCE, TRPV1 |
2.08087 |
|
[BP] GO:0006633 |
None
|
ALOX12, ALOX15, PTGES, PTGS1, PTGS2 |
2.06807 |
|
[BP] GO:0042058 |
None
|
ADORA1, APP, EGFR, GPER1, MMP9 |
2.06807 |
|
[BP] GO:0045785 |
positive regulation of cell adhesion
|
ALOX12, ALOX15, CDK6, KDR, PIK3CA, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.06087 |
|
[BP] GO:0051090 |
regulation of DNA binding transcription factor activity
|
ADORA3, APP, AR, CYP1B1, ESR1, ESR2, HSPA1A, KIT, PIM1, PRKCB |
2.05316 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.03673 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, DYRK1A, EGFR, PPARA, RORC |
2.02893 |
|
[BP] GO:0046649 |
lymphocyte activation
|
AXL, BCL2, FLT3, FUT7, KIT, PRKCB, PRKCD, RORC, SMAD3 |
2.02866 |
|
[BP] GO:0060359 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
2.02866 |
|
[BP] GO:1904375 |
None
|
AR, CSNK2A1, EGFR, GPER1, PRKCE |
2.02866 |
|
[BP] GO:2000351 |
None
|
GPER1, KDR, TEK, TERT |
2.01914 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.01914 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALOX12, ALOX15, ALPI, ALPL, APP, AR, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TERT, TRPV1 |
11.3354 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALOX12, ALOX15, ALOX5, ALPI, ALPL, APP, AR, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
10.1071 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ABCG2, ADORA1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, DRD2, EGFR, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, MET, PRKCG, PTGS2, SLC1A1, SLC22A1, SRC, TEK, TRPV1 |
8.56046 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CA4, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, F10, F3, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR2C, IGF1R, INSR, KDR, MET, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
8.26452 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ABCG2, ADORA1, ADORA3, ALOX15, APP, AXL, BACE1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, DUSP3, EGFR, F10, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, PRKCG, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
8.11594 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALOX15, ALPI, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, PIK3CA, PIK3CB, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TBXAS1, TEK, TRPV1, TYR |
7.23021 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, FLT3, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR2C, IGF1R, INSR, KDR, MET, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
6.98085 |
|
[CC] GO:0097060 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, TRPV1 |
5.9911 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CHRM1, CHRM2, CHRM4, CNR1, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, SLC22A2, SRC, TRPV1 |
5.37605 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, EGFR, F10, FLT3, GBA2, GPER1, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, PTGES, PTGS1, PTGS2, PTPN1, TBXAS1 |
5.00752 |
|
[CC] GO:0042734 |
None
|
CNR1, GPER1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
4.79826 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, EGFR, GBA2, GPER1, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HSD17B3, PTGES, PTGS1, PTGS2, TBXAS1 |
4.76248 |
|
[CC] GO:0014069 |
None
|
ADORA1, CHRM1, DRD2, GPER1, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
4.18224 |
|
[CC] GO:0099572 |
None
|
ADORA1, CHRM1, DRD2, GPER1, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
4.18224 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, GPER1, GRIK5, HMGCR, HSD17B3, HSPA1A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, XDH |
4.06159 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, BACE1, CA2, CHRM1, CHRM2, CNR1, CNR2, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PRKCG, PTGS2, SRC |
3.99561 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CBR1, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GRIA4, GRIK5, GRM1, GRM5, HMGCR, HSD17B3, HSPA1A, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.49218 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, GPER1, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, PTGES, SRC, TNKS2, TYR |
3.40519 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CBR1, CDC25B, CDK6, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GRIA2, GRIA4, GRIK5, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, INSR, KDR, KIT, MMP2, MMP9, NQO2, NR3C1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.3543 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.28412 |
|
[CC] GO:0031224 |
None
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, ALPI, ALPL, APP, AXL, BACE1, CA12, CA14, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP3A4, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, PTGES, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TBXAS1, TEK, TRPV1, TYR |
3.12236 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.09986 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CNR1, CNR2, DRD2, DRD3, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PIK3CA, PRKCG, PTGS2, SRC, TEK |
3.09817 |
|
[CC] GO:0098793 |
None
|
ADORA1, APP, CHRM1, CHRM2, DRD2, GPER1, GRIK5, SLC22A2 |
3.09047 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CBR1, CDK6, CHRM1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GRIA4, GRIK5, GRM1, GRM3, GRM5, HMGCR, HSD17B3, HSPA1A, IGF1R, INSR, KDR, KIT, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.07865 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, BACE1, CA2, CHRM1, CHRM2, CNR1, CNR2, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, PRKCG, PTGS1, PTGS2, SLC22A2, SRC, TRPV1 |
3.03585 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, BACE1, CA2, CDK6, CHRM1, CHRM2, CNR1, CNR2, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PIK3CA, PRKCG, PTGS2, SRC, TEK |
3.01892 |
|
[CC] GO:0043235 |
receptor complex
|
ABCG2, APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
2.59072 |
|
[CC] GO:0016021 |
None
|
ABCB1, ABCG2, ADORA1, ADORA3, ALPI, ALPL, APP, AXL, BACE1, CA12, CA14, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP3A4, DRD2, DRD3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPER1, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, PTGES, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TBXAS1, TEK, TRPV1, TYR |
2.52726 |
|
[CC] GO:0045211 |
None
|
CHRM1, CHRM2, CHRM4, GRIA2, GRIA4, GRIK5, GRM3, TRPV1 |
2.4659 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.30408 |
|
[CC] GO:0044309 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.27208 |
|
[CC] GO:0032589 |
None
|
ADORA1, GPER1, INSR, TRPV1 |
2.26725 |
|
[CC] GO:0045121 |
membrane raft
|
APP, BACE1, CNR1, EGFR, INSR, KDR, PTGS2, SRC, TEK |
2.26072 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, BACE1, CNR1, EGFR, INSR, KDR, PTGS2, SRC, TEK |
2.23996 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CNR1, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM3, INSR, PTGS1, SRC, TRPV1 |
2.09752 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CHRM1, CHRM2, CNR1, DRD2, GPER1, GRIA2, GRIA4, GRIK5, GRM3, INSR, PTGS1, SRC, TRPV1 |
2.09752 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, SLC22A1, TEK |
2.09752 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.03673 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX12, ALOX15, ALOX5, ALPI, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, PIM1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
22.2595 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ABCG2, ACHE, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
16.9131 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
15.1853 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.0239 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, HTR1A, HTR2C, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
12.2978 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AR, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, NR3C1, PPARA, RORC, TEK, TRPV1 |
11.9811 |
|
[MF] GO:0008270 |
zinc ion binding
|
ALPI, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
11.6346 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ABCG2, ACHE, AURKB, AXL, CDK6, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, DRD2, DRD3, DYRK1A, EGFR, FLT3, HSPA1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
11.6346 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AR, AXL, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, NR3C1, PPARA, RORC, TEK, TRPV1 |
10.8044 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AR, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, NR3C1, PPARA, PRKCE, RORC, SMAD3, TEK, TRPV1 |
10.5661 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AR, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, NR3C1, PPARA, RORC, TEK, TRPV1 |
10.5661 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
10.5234 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
10.3615 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.2215 |
|
[MF] GO:0005496 |
steroid binding
|
AR, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, GPER1, HSD11B2, HSD17B1, NR3C1, RORC, SHBG |
9.71249 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
8.99908 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX12, ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, TBXAS1, XDH |
8.91582 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
8.84019 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM4, DRD2, DRD3, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR1A, HTR2C |
8.62088 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, EGFR, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, TEK, TRPV1 |
8.11594 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, EGFR, F3, FLT3, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, TEK, TRPV1 |
8.11594 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, SRC, TBXAS1 |
7.89902 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HMGCR, HSD11B2, HSD17B1, NQO2, POLA1, PTGES, PTGS1, PTGS2, SRC, TBXAS1, XDH |
7.80385 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
7.65801 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, SRC, TBXAS1 |
7.55249 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, NR3C1, PPARA, RORC |
7.45249 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, GPER1, HSD17B1, IGF1R, INSR, NQO2, NR3C1, SHBG |
7.32785 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.26213 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1, POLB |
7.23912 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.16718 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
7.14678 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, TBXAS1, TYR |
7.03232 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, TBXAS1, TYR |
6.9039 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PPARA, RORC |
6.76052 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, GPER1, PPARA, RORC |
6.76052 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, XDH |
6.56855 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.477 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
6.4157 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TERT |
6.38826 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.35284 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.16229 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.82051 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
5.6838 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, GPER1, HSD11B2, HSD17B1, NR3C1, PPARA, RORC, SHBG, TRPV1 |
5.55764 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.29705 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ABCG2, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
5.2291 |
|
[MF] GO:0019899 |
enzyme binding
|
ALPI, APP, AR, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, HMGCR, HSPA1A, KIT, MET, NR3C1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
5.18109 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
5.11823 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, DNMT1, DYRK1A, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
5.11481 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
5.07368 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
5.01093 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ABCG2, ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GPER1, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SHBG, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, XDH |
4.77959 |
|
[MF] GO:0015238 |
None
|
ABCB1, ABCG2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.72592 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR, KIT |
4.71559 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ABCG2, ALOX15, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, F10, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
4.57254 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.46128 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.28206 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.23205 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
4.18862 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.09862 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3 |
4.05565 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX12, ALOX15, ALOX5, ALPI, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD2, DRD3, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPER1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SHBG, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.86083 |
|
[MF] GO:0008227 |
None
|
CHRM1, CHRM2, CHRM4, DRD2, HTR1A, HTR2C |
3.85564 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM4 |
3.7593 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2, GPER1 |
3.7593 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, KIT, MET, MMP9, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
3.73505 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ABCG2, ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, TRPV1, XDH |
3.63726 |
|
[MF] GO:0099528 |
None
|
CHRM1, CHRM2, CHRM4, HTR1A, HTR2C |
3.52327 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.49218 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CDK6, CSNK2A1, DYRK1A, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
3.22251 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DRD2, DRD3, GPER1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR2C |
2.98215 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.9551 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
2.9551 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.9551 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.93038 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
2.92744 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX12, ALOX15, ALOX5, PTGS2 |
2.86723 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.79208 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ABCG2, ADORA1, APP, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.78138 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.73031 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.73031 |
|
[MF] GO:0047977 |
hepoxilin-epoxide hydrolase activity
|
ALOX12, ALOX15 |
2.73031 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.73031 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.73031 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.73031 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.71357 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.6068 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.59072 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, ABCG2, AURKB, AXL, CDK6, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.58757 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.51052 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ABCG2, ACHE, AOX1, BCL2, DRD2, FLT3, HMGCR, KIT, NQO2, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TYR, XDH |
2.48012 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.47327 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.42981 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, BACE1, CDC25B, CDK6, CSNK2A1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
2.36551 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.35662 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD2, DRD3, HTR1A, HTR2C |
2.33962 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.33962 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.33962 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.33962 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.33962 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.33962 |
|
[MF] GO:0004052 |
arachidonate 12-lipoxygenase activity
|
ALOX12, ALOX15 |
2.33962 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.33962 |
|
[MF] GO:0051120 |
hepoxilin A3 synthase activity
|
ALOX12, ALOX15 |
2.33962 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.33962 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.33962 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.33962 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.33962 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.3174 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, NR3C1, POLA1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
2.313 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, NR3C1, POLA1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
2.30701 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.21285 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.16293 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM4 |
2.14602 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.09752 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.09752 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.09752 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.09752 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.09752 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.09752 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.09752 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.09752 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.05316 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.04801 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.03673 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PRKCB, SMAD3, SRC |
2.02866 |
