Component: Herba selaginellae doederleinii 石上柏

Description of the Component

Component ID
Latin Name
Herba selaginellae doederleinii
English Name
Doederlein's spikemoss herb
Chinese Pinyin Name
Shi Shang Bai
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Geo-authentic habitats (道地产区)
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3615 Bi Yan Ling Tablets 鼻咽灵片
TCMFx1169 Bi Yan Ling Tablet 鼻咽灵片
TCMFx4033 Kang Ai Ping Pills 抗癌平丸

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT575 PLA2G2A Phospholipase A2 group IIA Hydrolase P14555
TCMT599 UBE2N Ubiquitin-conjugating enzyme E2 N Transferase P61088
TCMT61 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 Unclassified Q07820
TCMT666 VCP Transitional endoplasmic reticulum ATPase Transporter P55072
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1099 Neuraminidase
TCMT1104 Sortase
TCMT1218 Staphylococcus aureus
TCMT1442 Leishmania donovani

Ingredient Structrues

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC680
Formula: C30H18O10

Ingredient ID: TCMC2288
Formula: C32H22O10

Ingredient ID: TCMC1831
Formula: C21H22NO4

Ingredient ID: TCMC1735
Formula: C27H32O14

Ingredient ID: TCMC1391
Formula: C32H22O10


Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC680 C30H18O10 Amentoflavone 538.09 -3.769 3.66 2.302 2 6 173.98 9 6 40 1
TCMC995 C35H60O6 Daucosterol 576.44 -0.4469 4.65 10.487 6 4 99.38 19 5 41 1
TCMC1391 C32H22O10 Isoginkgetin 566.12 -2.952 3.88 3.34 2 4 151.98 11 6 42 0
TCMC1735 C27H32O14 Naringin 580.18 -4.8082 2.89 -1.045 10 8 225.06 15 5 41 1
TCMC1831 C21H22NO4 Palmitine 352.15 -1.3839 3.22 2.969 0 0 40.8 8 4 26 0
TCMC2288 C32H22O10 Ginkgetin 566.12 -2.952 3.88 3.34 2 4 151.98 11 6 42 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)