TCM-ID Component

Description of the Component

Component ID	TCMH346
Latin Name	Selaginella uncinata
English Name	Hooked spikemoss
Chinese Pinyin Name	Cui Yun Cao
中文名	ç¿ äº‘è‰
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAJ4370-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx3684	Cui Lian Jie Du Tablets	ç¿ èŽ²è§£æ¯’ç‰‡
TCMFx6082	Yin Ju Gan Mao Tablets	é“¶èŠæ„Ÿå†’ç‰‡

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT101	PTPN1	Protein-tyrosine phosphatase 1B	Hydrolase	P18031
TCMT156	CYP19A1	Cytochrome P450 19A1	Oxidoreductase	P11511
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636
TCMT203	G6PD	Glucose-6-phosphate 1-dehydrogenase	Oxidoreductase	P11413
TCMT3	ALOX15	Arachidonate 15-lipoxygenase	Oxidoreductase	P16050
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT46	F3	Coagulation factor III	Unclassified	P13726
TCMT575	PLA2G2A	Phospholipase A2 group IIA	Hydrolase	P14555
TCMT61	MCL1	Induced myeloid leukemia cell differentiation protein Mcl-1	Unclassified	Q07820
TCMT63	PPARA	Peroxisome proliferator-activated receptor alpha	Nuclear receptor	Q07869
TCMT64	PPARD	Peroxisome proliferator-activated receptor delta	Nuclear receptor	Q03181
TCMT666	VCP	Transitional endoplasmic reticulum ATPase	Transporter	P55072
TCMT67	PPARG	Peroxisome proliferator-activated receptor gamma	Nuclear receptor	P37231
TCMT69	THRB	Thyroid hormone receptor beta-1	Nuclear receptor	P10828
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2
TCMT99	SHBG	Testis-specific androgen-binding protein	Unclassified	P04278

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1248	Hepatitis C virus

Ingredient Structrues

Ingredient ID: TCMC715
Formula: C20H32O2

Common Name	Arachidonic Acid
IUPAC Name	(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
Canonical SMILES	CCCCC/C=CC/C=CC/C=CC/C=CCCCC(=O)O
Standard InCHI	InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
Standard InCHIKey	YZXBAPSDXZZRGB-DOFZRALJSA-N
External Identifiers	ChEMBL [CHEMBL15594]; PubChem [444899];
Reference of Component-Ingredient Pair	21731166

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1063	Curcuma longa	Jiang Huang	å§œé»„
TCMH1939	Combretum indicum	Shi Jun Zi Ren	ä½¿å›åä»
TCMH1987	Silybum marianum	Shui Fei Ji	æ°´é£žè“Ÿ
TCMH346	Selaginella uncinata	Cui Yun Cao	ç¿ äº‘è‰
TCMH1409	Cannabis sativa	Ma Ren	éº»ä»
TCMH1396	Portulaca oleracea	Ma Chi Xian	é©¬é½¿è‹‹
TCMH1734	Homo sapiens	Ren Zhong Bai	äººä¸ç™½
TCMH309	Curcuma longa	Chuan Yu Jin	å·éƒé‡‘
TCMH1005	Cannabis sativa	Huo Ma Ren	ç«éº»ä»
TCMH2710	Homo sapiens	Zi He Che	ç´«æ²³è½¦

Ingredient ID: TCMC680
Formula: C30H18O10

Common Name	Amentoflavone
IUPAC Name	8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Canonical SMILES	Oc1ccc(cc1)c1cc(=O)c2c(o1)c(c(cc2O)O)c1cc(ccc1O)c1cc(=O)c2c(o1)cc(cc2O)O
Standard InCHI	InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H
Standard InCHIKey	YUSWMAULDXZHPY-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL63354]; PubChem [5281600];
Reference of Component-Ingredient Pair	22837955

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH143	Albizia julibrissin	Bei He Huan	åŒ—åˆæ¬¢
TCMH224	Thuja orientalis	Ce Bai Ye	ä¾§æŸå¶
TCMH346	Selaginella uncinata	Cui Yun Cao	ç¿ äº‘è‰
TCMH121	Biota orientalis	Bai Zi Ren	æŸåä»
TCMH1649	Toxicodendron succedaneum	Qi Shu Gen	æ¼†æ ‘æ ¹
TCMH1950	Herba selaginellae doederleinii	Shi Shang Bai	çŸ³ä¸ŠæŸ
TCMH1197	Selaginella tamariscina	Juan Bai	å·æŸ
TCMH223	Platycladus orientalis	Ce Bai Tan	ä¾§æŸç‚
TCMH1367	Apocynum venetum	Luo Bu Ma	ç½—å¸ƒéº»
TCMH114	Platycladus orientalis	Bai Ye	æŸå¶
TCMH60	Ginkgo biloba	Bai Guo	ç™½æžœ
TCMH61	Ginkgo biloba	Bai Guo Ren	ç™½æžœä»
TCMH2506	Ginkgo biloba	Yin Xing Ye	é“¶æå¶
TCMH2267	Periploca sepium	Xiang Jia Pi	é¦™åŠ çš®

Ingredient ID: TCMC2046
Formula: C21H28O5

Common Name	Sarcrassin E
IUPAC Name	methyl (4E,6E,11S)-11-methyl-10,15-dioxo-4-propan-2-yl-16-oxabicyclo[9.3.2]hexadeca-1(14),4,6-triene-7-carboxylate
Canonical SMILES	COC(=O)/C/1=C/C=C(CCC2=CCC[C@](C(=O)CC1)(C)OC2=O)/C(C)C
Standard InCHI	InChI=1S/C21H28O5/c1-14(2)15-7-9-16-6-5-13-21(3,26-20(16)24)18(22)12-11-17(10-8-15)19(23)25-4/h6,8,10,14H,5,7,9,11-13H2,1-4H3/b15-8+,17-10+/t21-/m0/s1
Standard InCHIKey	SSRWHVBVQPAITB-WYLCAHHTSA-N
External Identifiers	ChEMBL [CHEMBL470654]; PubChem [16091635];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH346	Selaginella uncinata	Cui Yun Cao	ç¿ äº‘è‰

Ingredient ID: TCMC1935
Formula: C21H32O2

Common Name	Pregnenolone
IUPAC Name	1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Canonical SMILES	O[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]2([C@H]3CC[C@@H]2C(=O)C)C)C1)C
Standard InCHI	InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,15-19,23H,5-12H2,1-3H3/t15-,16-,17+,18-,19-,20-,21+/m0/s1
Standard InCHIKey	ORNBQBCIOKFOEO-QGVNFLHTSA-N
External Identifiers	ChEMBL [CHEMBL253363]; PubChem [8955];
Reference of Component-Ingredient Pair	29100959

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH346	Selaginella uncinata	Cui Yun Cao	ç¿ äº‘è‰
TCMH670	Ligusticum sinense	Gao Ben	è—æœ¬
TCMH1121	Cardiospermum halicacabum	Jin Si Ku Lian	é‡‘ä¸è‹¦æ¥
TCMH1734	Homo sapiens	Ren Zhong Bai	äººä¸ç™½
TCMH1943	Punica granatum	Shi Liu	çŸ³æ¦´
TCMH1944	Punica granatum	Shi Liu Pi	çŸ³æ¦´çš®
TCMH1945	Punica granatum	Shi Liu Zi	çŸ³æ¦´å
TCMH2710	Homo sapiens	Zi He Che	ç´«æ²³è½¦
TCMH2050	Punica granatum	Suan Shi Liu	é…¸çŸ³æ¦´

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC680	C30H18O10	Amentoflavone	538.09	-3.769	3.66	2.302	2	6	173.98	9	6	40	1
TCMC715	C20H32O2	Arachidonic Acid	304.24	1.2639	3.44	8.349	2	1	37.3	16	0	22	2
TCMC1935	C21H32O2	Pregnenolone	316.24	0.261	3.55	4.833	2	1	37.3	5	4	23	0
TCMC2046	C21H28O5	Sarcrassin E	360.19	1.9336	3.22	2.727	5	0	69.67	7	2	26	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Selaginella uncinata ç¿ äº‘è‰

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC715

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC680

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2046

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1935

Occurrence of the ingredient across TCM components

Properties

Download Data

Component: Selaginella uncinata ç¿ äº‘è‰