| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA12, CA2, CA7, CHRM1, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, EGFR, ESR1, F10, F2, FABP3, FABP4, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS1, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, XDH |
17.7467 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AXL, BCL2, CA3, CA9, CNR1, CNR2, CSNK2A1, CXCL8, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, GRIK5, GRM5, HMGCR, HSD17B2, IGF1R, INSR, MMP2, MMP9, PIK3CA, POLB, PPARA, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
15.6288 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CNR1, CNR2, CSNK2A1, CXCL8, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, PIK3CA, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
15.097 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CNR1, CNR2, CSNK2A1, CXCL8, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PIK3CA, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
12.8894 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.5817 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, F2, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
11.3867 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, F2, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
11.3625 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, FABP3, FABP4, FUT7, HMGCR, HSD11B1, HSD17B1, HSD17B2, MET, PIK3CA, PIK3CB, PPARA, PPARD, PTGS1, PTGS2, TBXAS1, TRPV1 |
10.9539 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.9539 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, F2, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
10.2995 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, FABP3, FUT7, GLO1, HMGCR, HSPA1A, PIK3CA, PIM1, PPARA, PPARD, PTAFR, PTGS1, PTGS2, TBXAS1, TYR, XDH |
10.2995 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, F2, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
10.1377 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, F10, F2, FLT3, GPR35, GRM1, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.78987 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CNR1, CSNK2A1, CXCL8, CYP1B1, EGFR, ESRRA, F10, F2, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.77631 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARD, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
9.77631 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AXL, BCL2, CYP1B1, EGFR, F10, F2, FLT3, GPR35, GRM1, HMGCR, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.59215 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
9.578 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CSNK2A1, CXCL8, CYP19A1, CYP1B1, EGFR, F10, F2, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1 |
9.57546 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CNR1, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.45728 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA, PPARD, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
9.45728 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
9.33378 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PPARD, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
9.28746 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CXCL8, CYP1A1, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, IGF1R, INSR, KDR, MMP2, PIK3CA, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
8.8601 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, APP, BCL2, CA2, CA9, CSNK2A1, CXCL8, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GRM5, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1 |
8.83998 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AXL, BCL2, CXCL8, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PIK3CA, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SMAD3, SRC, TRPV1 |
8.77533 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
8.72855 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CXCL8, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD17B2, PPARD, PRKCE, PTAFR, PTGS2, RORC, SRC, TYR |
8.63304 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA3, CA6, CA9, CHRM2, CNR1, CNR2, CSNK2A1, CXCL8, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, F10, F2, FABP3, FABP4, FLT3, GRIK5, GRM1, GRM5, HMGCR, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR |
8.63304 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CHRM1, CNR1, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.60992 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, ESRRA, FLT3, PRKCE, PRKCG, PTAFR, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
8.59135 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, F10, F2, FLT3, GPR35, GRM1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.45931 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, BCL2, CDC25B, CHRM1, CSNK2A1, CXCL8, CYP1B1, EGFR, ESR1, ESRRA, F2, FABP3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARD, PRKCA, PTAFR, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
8.43471 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CXCL8, CYP1B1, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, PIK3CA, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, RORC, SRC, TRPV1 |
8.30418 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
8.28071 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
8.25262 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CHRM1, CNR1, CYP19A1, EGFR, F2, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, INSR, MMP12, MMP9, PIK3CB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TRPV1 |
8.24097 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CHRM4, CSNK2A1, CXCL8, EGFR, F2, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
8.21628 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
8.20171 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, ESR1, HMGCR, HSD11B1, HSD17B1, HSD17B2, PPARD |
8.15505 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
8.00183 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, ESRRB, F2, FABP3, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.89841 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, ESRRB, F2, FABP3, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.89841 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PPARD, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.89841 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, INSR, PPARA, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TEK, TRPV1 |
7.87929 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, EGFR, ESR1, F2, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, INSR, MET, PIK3CA, PIK3CB, POLA1, POLB, PRKCB, PRKCE, SMAD3, SRC, TRPV1 |
7.87823 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.84893 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.84893 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.83249 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, APEX1, AXL, BCL2, CA3, CA9, CNR1, CNR2, CYP1A1, CYP1B1, EGFR, FABP3, HMGCR, KDR, POLB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TRPV1 |
7.81468 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.74907 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CHRM1, CHRM4, CXCL8, CYP19A1, CYP1B1, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PPARD, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
7.72831 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, PPARA, PPARD, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
7.72831 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, HMGCR, HSD11B1, HSD17B1, HSD17B2, NQO2, PPARD, PTGS1, PTGS2, TBXAS1, TYR, XDH |
7.68341 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
7.65398 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CXCL8, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM1, GRM5, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NUAK1, PIK3CA, POLA1, POLB, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
7.49366 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CXCL8, CYP19A1, CYP1B1, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PPARD, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
7.44329 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD17B1, HSD17B2, PPARD, PRKCA, PRKCE, SLC22A1 |
7.39188 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIM1, PPARD, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.36586 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.32814 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CNR1, CNR2, CYP19A1, DUSP3, EGFR, ESR1, F2, FABP4, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, XDH |
7.21035 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, CNR1, CNR2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCE, PTGS2 |
7.13045 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, CNR1, CNR2, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCE, PTGS2 |
7.13045 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, FABP3, FABP4, FUT7, HMGCR, MET, PIK3CA, PIK3CB, PPARA, PPARD, PTGS1, PTGS2, TBXAS1 |
7.09193 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CNR1, EGFR, F2, HCAR2, HMGCR, KDR, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
7.04316 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
7.0207 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F2, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.02061 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CXCL8, CYP19A1, CYP1B1, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PPARD, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.98023 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, ESRRB, F2, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.89125 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, EGFR, FABP3, FLT3, GRM5, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
6.87546 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AXL, BCL2, CHRM1, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRB, F10, F2, FABP4, GRM1, GRM5, GRM8, HMGCR, HSD17B2, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PPARD, PRKCD, PRKCG, PTAFR, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
6.87512 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, CXCL8, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.67936 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.67936 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PIK3CA, POLB, PPARA, PPARD, PTPRS, SMAD3, SRC, TEK, TYR |
6.66902 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, F2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
6.66731 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CXCL8, CYP19A1, EGFR, ESR1, F2, FABP4, HMGCR, KDR, MET, MMP12, PPARA, PPARD, PRKCA, PRKCD, PRKCG, PTGS2, PTPRS, SMAD3, TEK |
6.66731 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, APP, BCL2, CA12, CA2, CA7, CNR1, EGFR, ESR1, F2, FABP3, FABP4, GPR35, GRIK5, GRM1, GRM5, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.61131 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, F2, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
6.60162 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AXL, BCL2, CA1, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CXCL8, CYP1B1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
6.59058 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, APP, AXL, BCL2, CA2, CHRM1, CHRM2, CNR1, CXCL8, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F2, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPRS, SLC1A1, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
6.49132 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, CXCL8, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.48748 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7, GRM5, PTAFR |
6.48371 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, MMP9, PRKCD, PTGS2, SRC |
6.43864 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CNR1, CNR2, CYP1A1, CYP1B1, HMGCR, KDR, POLB, PRKCD, PRKCE, SRC |
6.4326 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS1, PTGS2, TBXAS1 |
6.41427 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, EGFR, GRM1, GRM3, GRM5, GRM8, PTGS2 |
6.41427 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CXCL8, CYP19A1, CYP1B1, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PPARD, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.39309 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CXCL8, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F2, FABP4, FLT3, GPR35, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TRPV1, XDH |
6.38037 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, PPARD, PTGS1, PTGS2, TBXAS1 |
6.36179 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, EGFR, FABP3, FLT3, GRM5, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
6.35193 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CHRM1, CHRM2, CNR1, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD11B1, HSD17B2, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PPARD, PRKCA, PRKCD, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
6.35193 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, CXCL8, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.35103 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.25643 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.25087 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, F2, FABP3, FLT3, HCAR2, HMGCR, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
6.18954 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, EGFR, GRM1, HMGCR, HSPA1A, MMP2, POLB, PPARA, PPARD, PRKCB, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK, TRPV1, TYR |
6.18954 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, CXCL8, EGFR, F10, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TEK |
6.15236 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
6.06442 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DUSP3, EGFR, ESR1, F2, FABP4, FLT3, GRM1, GRM3, GRM5, HMGCR, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
6.01673 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, FABP4, HSPA1A, MMP12, MMP2, PPARA, PPARD, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK |
5.9844 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, BCL2, CNR1, CNR2, CXCL8, CYP19A1, DUSP3, EGFR, ESR1, ESR2, F2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PPARD, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, XDH |
5.95351 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AURKB, AXL, BCL2, CSNK2A1, CXCL8, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, F2, FLT3, GPR35, GRM1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
5.94468 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, CXCL8, EGFR, F2, FLT3, FUT7, HSPA1A, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, RORC, SMAD3, SRC, TRPV1 |
5.88337 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, ESRRB, F2, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
5.84948 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, BCL2, CHRM1, CHRM4, CYP1A1, EGFR, ESR1, FLT3, MET, PIK3CB, PIM1, POLA1, PPARD, PRKCD, SRC, TEK, TYR |
5.84009 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CHRM1, CSNK2A1, EGFR, ESR1, F2, FLT3, HMGCR, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PPARD, PRKCA, PTAFR, PTGS2, TEK |
5.83735 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.75909 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CNR1, CNR2, CXCL8, CYP19A1, DUSP3, ESR1, ESRRA, F2, HCAR2, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, PTPRS, SMAD3, SRC |
5.71205 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.65924 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CA3, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
5.6591 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, DUSP3, ESR1, FABP4, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
5.65564 |
|
[BP] GO:0007193 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, GRM1, GRM3, GRM5, GRM8 |
5.65052 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, MMP2, POLB, PPARA, PPARD, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.59952 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.55169 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CNR2, CXCL8, CYP1A1, CYP1A2, CYP1B1, EGFR, F2, HSPA1A, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PPARD, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1 |
5.54715 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, PRKCG, SRC, TEK |
5.49412 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, F2, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
5.4793 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, F2, PPARA, PPARD, PRKCD, SMAD3, TEK |
5.44317 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2, PRKCE |
5.39769 |
|
[BP] GO:0006811 |
None
|
ABCB1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, GRIA2, GRIA4, GRIK5, PPARA, PPARD, PRKCB, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
5.37773 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, KDR, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
5.26895 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, F10, F2, FLT3, IGF1R, INSR, KDR, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP2A |
5.26497 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, BCL2, CNR1, CNR2, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PIK3CA, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
5.26133 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CHRM1, CYP19A1, EGFR, F2, HCAR2, INSR, MMP12, PPARD, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
5.25503 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, MMP2, PPARA, PPARD, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.25303 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, F2, FLT3, GRM1, GRM5, HMGCR, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.23843 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
F2, FABP3, FLT3, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
5.2171 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, ESR1, F2, FLT3, GRM1, GRM5, HMGCR, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.17547 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
5.17009 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, EGFR, FLT3, GRM1, HMGCR, INSR, KDR, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
5.17009 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AXL, BCL2, CA2, CNR1, CXCL8, CYP1B1, EGFR, ESRRB, F2, HCAR2, HMGCR, HSPA1A, KDR, MET, MMP12, MMP9, PIM1, PRKCA, PRKCB, PRKCE, PTAFR, PTGS2, SLC1A1, SMAD3, SRC, TEK, TRPV1 |
5.16751 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, F2, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
5.13528 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, MMP2, PPARA, PPARD, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.13324 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, F2, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
5.11829 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, FABP4, PPARA, PPARD, PRKCD, PTGS2, SMAD3, TEK |
5.07489 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, F2, MMP12, PPARA, PPARD, PRKCD, SMAD3, TEK |
5.07489 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
5.00432 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, DUSP3, EGFR, F2, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
5.00019 |
|
[BP] GO:0006855 |
None
|
ABCB1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
4.94036 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, EGFR, F2, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
4.93741 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, CXCL8, EGFR, ESR1, FLT3, GRM5, IGF1R, INSR, MMP2, PRKCD, PRKCE, PTAFR, PTGS2, SMAD3, SRC, TRPV1 |
4.92571 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, EGFR, F2, PPARA, PPARD, SMAD3 |
4.90687 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, KDR, PRKCD, PRKCE, PTAFR, PTGS2, SRC, TRPV1 |
4.90283 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.88319 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.85748 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, EGFR, F2, FLT3, GRM1, GRM5, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
4.83702 |
|
[BP] GO:0007187 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, CNR2, GRM1, GRM3, GRM5, GRM8 |
4.83274 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.80726 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PPARA, PPARD, PTGS1, PTGS2, TBXAS1 |
4.79834 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD17B1, HSD17B2 |
4.79834 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GRM5, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
4.79834 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.77983 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, PTAFR, PTGS2, RORC, SRC, TRPV1 |
4.77407 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HMGCR, HSD11B1, HSD17B1, HSD17B2, PIK3CA, PIK3CB, PPARD, PTGS1, PTGS2 |
4.77113 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.72142 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, APP, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, F2, FLT3, GRM1, GRM5, HSPA1A, INSR, MET, MMP9, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.63186 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.58845 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
4.58845 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.58845 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CHRM1, CNR1, EGFR, F2, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.54277 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, CXCL8, F2, PIK3CA, PIK3CB, POLB, PTAFR, PTGS1, PTGS2, TRPV1 |
4.54002 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
4.52606 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTAFR, PTGS2 |
4.48446 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, EGFR, GRIK5, INSR, PTGS2, SLC1A1, SLC22A2, SLC22A3, SMAD3, TRPV1 |
4.47511 |
|
[BP] GO:0003018 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PPARD, PTAFR, PTGS2, SRC, TEK |
4.46004 |
|
[BP] GO:0007188 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, GRM1, GRM3, GRM5, GRM8 |
4.43835 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGS1, PTGS2, TBXAS1 |
4.43686 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, NQO2, PTGS1, RORC |
4.42939 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, CNR2, CXCL8, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, XDH |
4.4135 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, F2, FABP3, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.4061 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CXCL8, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTAFR, SMAD3, SRC, TEK |
4.4061 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, CNR2, CXCL8, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, XDH |
4.39494 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DUSP3, EGFR, F2, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.34509 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, EGFR, F10, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
4.32328 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, GRM5, PRKCD, PTAFR |
4.28295 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, F2, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.28295 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, APP, BCL2, CA2, CA7, CHRM1, CNR1, F2, GPR35, GRM5, MMP9, PRKCD, PRKCE, PTAFR, PTGS2 |
4.26258 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
4.25777 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GRM5, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
4.25021 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, SRC |
4.25021 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA, PRKCD, PRKCE |
4.25021 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CNR1, CNR2, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
4.19215 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, APP, AXL, BCL2, CA2, CHRM1, CHRM2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FLT3, HSD11B1, HSD17B2, INSR, KDR, MMP9, PIK3CA, PIM1, POLB, PPARA, PPARD, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TYR |
4.16522 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR, HMGCR, PPARD |
4.16066 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
4.16066 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.14416 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
4.14129 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, F2, HMGCR, PPARA, PPARD, PRKCD, PTPRS, SMAD3, TEK |
4.14129 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, ESR1, F2, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, POLA1, PRKCB, PRKCE, SMAD3, TRPV1 |
4.13978 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, BCL2, CNR1, CSNK2A1, DUSP3, ESR1, ESR2, ESRRA, F2, FABP4, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PIK3CA, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
4.13659 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PPARD, PTAFR, PTGS2 |
4.09511 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.09511 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, PPARD, RORC, SRC |
4.07779 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HMGCR, PPARD, PTAFR, TYR |
4.0569 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC, SRC |
4.05572 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.02698 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, EGFR, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.01546 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, EGFR, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.00069 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
3.91178 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, ESR1, F2, GPR35, GRIK5, GRM1, GRM5, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.90978 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, EGFR, GRM5, IGF1R, INSR, MMP2, PRKCD, PTAFR, PTGS2, SRC, TRPV1 |
3.90977 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD17B1, HSD17B2 |
3.88504 |
|
[BP] GO:0099536 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
3.88504 |
|
[BP] GO:0099537 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
3.88504 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, APP, CA2, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CXCL8, ESR1, F2, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, INSR, PIK3CA, PIK3CB, PTAFR, SRC |
3.88504 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CHRM1, CNR1, EGFR, F2, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.88504 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CBR1, CDC25B, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.86885 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CBR1, CDC25B, CHRM1, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.81773 |
|
[BP] GO:0007197 |
None
|
CHRM1, CHRM2, CHRM4 |
3.79885 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, CHRM1, EGFR, F2, HCAR2, MMP12, PPARD, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.77719 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PPARD, PTGS2, TRPV1, TYR |
3.76464 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.75667 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, HMGCR, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
3.75667 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
3.75087 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, CHRM1, CHRM2, EGFR, GPR35, GRM1, HCAR2, PRKCA, PTAFR, PTGS2, SLC1A1, SMAD3, TRPV1 |
3.74594 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, EGFR, ESR1, F2, FLT3, GRM1, GRM5, HSPA1A, INSR, PIK3CA, PIK3CB, PRKCD, PRKCE, PTAFR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.72805 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.69574 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.68886 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, EGFR, F2, FLT3, GRM1, GRM5, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
3.67847 |
|
[BP] GO:0015893 |
None
|
ABCB1, CA2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.67847 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.65138 |
|
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, SRC |
3.63865 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.60398 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR, PPARD |
3.60011 |
|
[BP] GO:0007154 |
None
|
ADORA1, AXL, BCL2, CHRM1, CHRM2, CHRM4, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, PTGS2, SLC1A1, TEK, TRPV1 |
3.59541 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, CNR1, CSNK2A1, EGFR, ESR1, ESR2, F2, GRIK5, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PPARD, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.59018 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CHRM1, CNR1, EGFR, F2, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.5894 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.5791 |
|
[BP] GO:0003013 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PPARD, PTAFR, PTGS2, SRC, TEK |
3.57865 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
3.57164 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.57164 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.54576 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.54576 |
|
[BP] GO:0007207 |
None
|
CHRM1, CHRM2, CHRM4 |
3.54079 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, F2, KDR, PRKCE, SRC, TRPV1 |
3.53737 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CSNK2A1, CYP1A1, CYP1A2, CYP3A4, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, GLO1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.52947 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.52724 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.52724 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.52724 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.51674 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, EGFR, F2, FLT3, GRM1, GRM5, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
3.51471 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, EGFR, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.5061 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AURKB, AXL, BCL2, CNR1, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.48815 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.46759 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CHRM1, CNR1, EGFR, GRM5, HMGCR, INSR, PRKCG, PTGS2 |
3.46593 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.4515 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DUSP3, EGFR, HMGCR, KDR, PRKCA, PTPN1, SRC, TEK |
3.44062 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, PRKCD, SRC, TEK |
3.4369 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, CHRM1, EGFR, F2, HCAR2, MMP12, PPARD, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.4369 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CXCL8, CYP1A1, CYP1A2, F2, MMP12, PPARD, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
3.4369 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, APP, BCL2, CHRM1, CNR1, CNR2, CYP1B1, EGFR, GRM1, GRM5, GRM8, HMGCR, INSR, PIK3CA, PPARD, PRKCG, PTAFR, PTGS2, SRC, TEK, TRPV1, TYR |
3.42744 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CXCL8, CYP1A1, CYP1A2, PPARD, PTGS2, SRC |
3.40582 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, CXCL8, EGFR, F2, FABP4, KDR, MET, PRKCA, PTGS2, SMAD3 |
3.37969 |
|
[BP] GO:0051234 |
None
|
ABCB1, ACHE, ADORA1, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, CXCL8, EGFR, F10, F2, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, MMP12, MMP9, PPARA, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
3.37333 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.37333 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.36887 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC, SRC |
3.34952 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD, TNKS |
3.34842 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.34115 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.34115 |
|
[BP] GO:1903034 |
regulation of response to wounding
|
F2, HMGCR, PPARD, PRKCA, PRKCD, PRKCE, PTPRS, SMAD3 |
3.33708 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AURKB, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, GRM3, GRM8, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, PPARA, PPARD, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
3.33306 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.33101 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, EGFR, ESR1, PPARA, PRKCG, RORC, SRC, TOP2A |
3.3306 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, EGFR, PRKCE, PTGS2 |
3.31243 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
3.31243 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TNKS, TOP2A |
3.29569 |
|
[BP] GO:0051179 |
None
|
ABCB1, ACHE, ADORA1, ALOX15, ALOX5, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, CXCL8, EGFR, ESR1, F10, F2, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, MMP12, MMP9, PPARA, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TNKS2, TRPV1, XDH |
3.28616 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.28259 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CXCL8, CYP1B1, EGFR, F2, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCD, SRC, TEK |
3.28222 |
|
[BP] GO:0006810 |
None
|
ABCB1, ACHE, ADORA1, ALOX15, ALOX5, APP, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CHRM1, CXCL8, F10, F2, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, MMP12, MMP9, PPARA, PPARD, PRKCB, PRKCD, PRKCE, PTAFR, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
3.28222 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CXCL8, CYP1B1, EGFR, GRM5, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, SRC, TEK |
3.282 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.28081 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.27617 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CXCL8, CYP1B1, EGFR, F2, FUT7, KDR, MET, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCD, PTAFR, SRC, TEK |
3.26577 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DUSP3, ESR1, F2, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTAFR, PTPN1, PTPRS, SMAD3, SRC |
3.26577 |
|
[BP] GO:0097746 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PPARD, PTAFR, PTGS2 |
3.25763 |
|
[BP] GO:0035296 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PPARD, PTAFR, PTGS2 |
3.25763 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PPARD, PTGS2, TYR |
3.25069 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, BCL2, CHRM1, CNR1, CSNK2A1, EGFR, F2, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.24919 |
|
[BP] GO:0007268 |
None
|
CHRM1, CHRM2, CHRM4, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
3.24919 |
|
[BP] GO:0098916 |
None
|
CHRM1, CHRM2, CHRM4, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1 |
3.24919 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CXCL8, CYP1A1, CYP1A2, F2, MMP12, PPARD, PRKCD, PTAFR, PTGS2, SMAD3, SRC |
3.24375 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, F2, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.24301 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, PRKCD, PRKCE, PTPN1, SRC |
3.24301 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, POLB, PRKCD, PTGS2 |
3.24301 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, PPARD, PTGS2, SRC, TRPV1, TYR |
3.23796 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HMGCR, HSD11B1, HSD17B1, HSD17B2 |
3.22429 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CXCL8, CYP1A1, CYP1A2, PPARD, PTGS2, SRC |
3.20626 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD, TNKS |
3.17504 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
3.1742 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.1742 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
3.16483 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARD, PTGS1, PTGS2, TBXAS1, TYR |
3.15356 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.14852 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, F2, PRKCD, PTGS2, SMAD3, SRC |
3.14852 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
3.14852 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DUSP3, EGFR, INSR, PRKCA, PRKCE, SRC |
3.13536 |
|
[BP] GO:0050880 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PPARD, PTAFR, PTGS2 |
3.10756 |
|
[BP] GO:0032409 |
None
|
ABCB1, APP, BCL2, GPR35, GRM5, MMP9, PRKCD, PRKCE, PTAFR |
3.10051 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.09843 |
|
[BP] GO:0035150 |
None
|
ADORA1, CHRM1, EGFR, HMGCR, PPARD, PTAFR, PTGS2 |
3.08968 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, IGF1R, INSR, KDR, MET, MMP12, PPARA, PPARD, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
3.04928 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CXCL8, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TNKS, TOP2A |
3.04928 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.04747 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
3.04084 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.03559 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.03559 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, EGFR, HCAR2, MMP12, PPARD, PRKCE, PTAFR, SRC, TRPV1 |
3.03521 |
|
[BP] GO:0010359 |
None
|
ABCB1, GRM5, PTAFR |
3.03521 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, EGFR, GRM1, GRM5, HMGCR, INSR, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
2.9919 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, CXCL8, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, XDH |
2.96708 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.96155 |
|
[BP] GO:0007267 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1, TEK |
2.96155 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, EGFR, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
2.95485 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, GPR35, MMP9, PRKCE, PTGS2 |
2.94752 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.93665 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, PRKCA, PRKCB, PRKCD |
2.9365 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CXCL8, CYP1A1, CYP1A2, EGFR, F2, HMGCR, MMP12, PPARD, PRKCD, PTAFR, PTGS2, SMAD3, SRC, TRPV1, TYR |
2.9365 |
|
[BP] GO:0001525 |
angiogenesis
|
CXCL8, CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.9365 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTAFR, PTGS2, SRC |
2.9365 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.93185 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, EGFR, HMGCR, KDR, PRKCA, SRC, TEK |
2.91889 |
|
[BP] GO:0061041 |
regulation of wound healing
|
F2, HMGCR, PPARD, PRKCA, PRKCD, PRKCE, SMAD3 |
2.9167 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.90192 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DUSP3, INSR, PRKCA |
2.90146 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, F2, FLT3, KDR, PPARD, TEK |
2.89804 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, CHRM1, F10, F2, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
2.87651 |
|
[BP] GO:0042307 |
positive regulation of protein import into nucleus
|
APP, EGFR, F2, PRKCD, PTGS2, SMAD3 |
2.87587 |
|
[BP] GO:0002684 |
positive regulation of immune system process
|
APP, AXL, BCL2, CA2, CNR1, CXCL8, HCAR2, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, SRC |
2.8692 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PTAFR, PTGS2, TEK, TRPV1, TYR |
2.8692 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CXCL8, CYP1B1, EGFR, HSPA1A, MMP9, NUAK1, POLA1, POLB, PPARD, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TOP2A, TRPV1 |
2.86802 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CNR1, CYP19A1, EGFR, HCAR2, HMGCR, PPARD, PRKCA, PRKCE |
2.86109 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AXL, BCL2, CA2, CNR1, CXCL8, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F2, HMGCR, INSR, KDR, NUAK1, PIK3CA, PIM1, PPARA, PPARD, PRKCA, PRKCB, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
2.85239 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CXCL8, CYP1B1, EGFR, F2, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCD, SRC, TEK |
2.84055 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CNR1, CYP19A1, EGFR, GRIK5, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCE, PTAFR, SRC, TRPV1 |
2.84033 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.83861 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, PPARD, PTGS2, SRC, TRPV1, TYR |
2.83861 |
|
[BP] GO:1904591 |
positive regulation of protein import
|
APP, EGFR, F2, PRKCD, PTGS2, SMAD3 |
2.83749 |
|
[BP] GO:0008217 |
None
|
ADORA1, CNR1, PPARA, PTAFR, PTGS1, PTGS2, SMAD3 |
2.82348 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, PTPRS, XDH |
2.82348 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC |
2.81927 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, ESR1, F2, GPR35, GRM1, GRM5, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
2.81643 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.81481 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, BCL2, CSNK2A1, EGFR, ESR2, F2, HSPA1A, INSR, PIK3CA, PIM1, PPARD, PTPRS, SMAD3, TNKS2 |
2.79843 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, PPARD |
2.78718 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GRM5, IGF1R, INSR, PRKCD, SRC |
2.78037 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
2.77492 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.76634 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.76634 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.76634 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CXCL8, CYP1B1, KDR, PRKCA, PRKCB, PTGS2, TEK |
2.74904 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TNKS |
2.74756 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, PTAFR, PTGS2, SRC |
2.735 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
2.70523 |
|
[BP] GO:0006940 |
None
|
ADORA1, CHRM1, CHRM2, PTAFR, PTGS2 |
2.70134 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.69973 |
|
[BP] GO:0006775 |
fat-soluble vitamin metabolic process
|
CBR1, CYP1A1, CYP3A4, PPARD |
2.69973 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.69973 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
2.69893 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, MMP2, MMP9, PPARD, PTAFR, PTGS2, SRC, TOP2A |
2.6972 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARD, PTGS1, PTGS2, TBXAS1, TYR |
2.6972 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.6972 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.6972 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.6972 |
|
[BP] GO:0015872 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.6972 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
2.6972 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
2.6972 |
|
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
F2, FLT3, KDR, PPARD, TEK |
2.68349 |
|
[BP] GO:0050900 |
leukocyte migration
|
CNR2, CXCL8, F2, FUT7, MMP1, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.68332 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
2.66622 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, PTAFR, PTGS2, SRC |
2.65559 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.65559 |
|
[BP] GO:0016311 |
None
|
ALPL, APEX1, BCL2, CA3, CDC25B, DUSP3, POLB, PTPN1, PTPRS |
2.65329 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AXL, CXCL8, EGFR, ESR1, FLT3, PPARD, PRKCE, PTAFR, RORC, SRC |
2.63658 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX15, CYP19A1, CYP3A4, HMGCR, PTAFR, TYR |
2.63658 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CNR1, CYP19A1, EGFR, GRIK5, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCE, PTAFR, SRC |
2.6356 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CSNK2A1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.62326 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CSNK2A1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.62326 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, PPARD, PTGS1, PTGS2, TBXAS1, TYR |
2.61974 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, EGFR, FLT3, GRM1, GRM5, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.61974 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PPARD, PTGS2, SRC |
2.60762 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR |
2.60486 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.60486 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.60414 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
CA2, CA7, PRKCE |
2.60414 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CNR2, CXCL8, CYP1B1, EGFR, F2, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PPARD, PRKCA, PRKCD, PTGS2, SRC, TEK, TUBB3 |
2.60036 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
2.57819 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, BCL2, CDC25B, CSNK2A1, DUSP3, EGFR, ESR1, F2, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.56829 |
|
[BP] GO:0022898 |
None
|
ABCB1, APP, BCL2, GPR35, GRM5, MMP9, PRKCE, PTAFR |
2.55161 |
|
[BP] GO:0023052 |
None
|
ADORA1, CHRM1, CHRM2, CHRM4, CNR1, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SLC1A1, TEK |
2.54307 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CSNK2A1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.53863 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, PTGS1, PTGS2 |
2.53582 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, PRKCD, SRC, TEK |
2.529 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.529 |
|
[BP] GO:0090066 |
None
|
ADORA1, ALOX15, CHRM1, EGFR, HMGCR, PPARD, PRKCD, PRKCE, PTAFR, PTGS2 |
2.529 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, EGFR, HSPA1A |
2.52608 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.51639 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CHRM1, CNR1, CNR2, CYP1B1, EGFR, GRM1, GRM5, GRM8, HMGCR, INSR, PRKCG, PTGS2, TRPV1, TYR |
2.50247 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.50002 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.50002 |
|
[BP] GO:0007566 |
embryo implantation
|
MMP2, MMP9, PPARD, PTGS2 |
2.50002 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CNR1, EGFR, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCE, SRC |
2.48568 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, EGFR, GRM5, HMGCR, INSR, PRKCG, PTGS2 |
2.47638 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, INSR, PPARA, PRKCE, PTAFR, RORC, SRC |
2.47351 |
|
[BP] GO:0038128 |
None
|
EGFR, PIK3CA, PRKCA, SRC |
2.46016 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CXCL8, CYP1B1, KDR, PRKCA, PRKCB, PTGS2, TEK |
2.45959 |
|
[BP] GO:0051937 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.43342 |
|
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, EGFR, PRKCE, PTAFR, SRC |
2.41671 |
|
[BP] GO:0042060 |
None
|
ALOX15, EGFR, PPARA, PPARD, SMAD3 |
2.4068 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CSNK2A1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.39991 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.39618 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
2.37516 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, EGFR, GRM1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.37516 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.37516 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.37516 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.37516 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.37516 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, CXCL8, EGFR, INSR, KDR, SMAD3, SRC, TRPV1 |
2.37482 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CHRM1, CSNK2A1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.36908 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.36908 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.36908 |
|
[BP] GO:0007213 |
None
|
CHRM1, CHRM2, CHRM4 |
2.36908 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.36908 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.36908 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, PPARA, PTAFR |
2.36046 |
|
[BP] GO:1903035 |
None
|
F2, HMGCR, PRKCD, PTPRS, SMAD3 |
2.35318 |
|
[BP] GO:0070542 |
None
|
FABP3, PRKCE, PTAFR, PTGS2, SRC |
2.35318 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA3, ALOX15, APP, AXL, BCL2, CNR2, CXCL8, F2, PIK3CA, PIK3CB, POLB, PRKCD, PTAFR, PTGS1, PTGS2, SRC, TRPV1 |
2.35239 |
|
[BP] GO:0050865 |
regulation of cell activation
|
APP, AXL, BCL2, CNR1, CNR2, DUSP3, F2, PIK3CA, PRKCA, PRKCD, PTAFR, SRC |
2.35077 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP4, FLT3, GLO1, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.34927 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MET, MMP12, PPARA, PPARD, PRKCD, PTAFR, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.34874 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.30859 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.29853 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.29853 |
|
[BP] GO:0045321 |
leukocyte activation
|
ALOX5, AXL, BCL2, CXCL8, FLT3, FUT7, HSPA1A, MMP9, PRKCB, PRKCD, PRKCE, PTAFR, RORC, SMAD3, TRPV1 |
2.29408 |
|
[BP] GO:1903829 |
positive regulation of cellular protein localization
|
APP, BCL2, CHRM1, EGFR, F2, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
2.29408 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, PRKCD, PTAFR, PTGS2 |
2.28989 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, EGFR, HCAR2, MMP12, PPARD, PRKCE, SRC |
2.27639 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.25708 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.24329 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AXL, BCL2, CA2, CNR1, CXCL8, CYP1B1, ESRRB, HMGCR, INSR, KDR, PIM1, PPARD, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK |
2.24315 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.22974 |
|
[BP] GO:0007200 |
None
|
CHRM1, CHRM2, CHRM4, ESR1, GRM5 |
2.19871 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, FABP3, FABP4, FUT7, HSPA1A, MMP1, MMP12, MMP2, MMP9, PIK3CB, PPARD, SRC, XDH |
2.19809 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, GPR35, HMGCR, HSPA1A, MMP9, PRKCB, PRKCE, PTGS2 |
2.18551 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, INSR, PIK3CB, PTPN1, SRC |
2.18015 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, PTAFR, PTGS2 |
2.17447 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.16383 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, PPARA, PPARD, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.15833 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AURKB, CSNK2A1, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HMGCR, HSPA1A, IGF1R, KDR, MMP12, MMP9, PPARA, PPARD, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
2.15697 |
|
[BP] GO:0031349 |
positive regulation of defense response
|
CNR1, EGFR, FABP4, HSPA1A, MMP12, MMP2, PRKCD, PRKCE, PTGS2, SRC |
2.15545 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.12736 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.12214 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.12214 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.12214 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.12214 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.12214 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.12214 |
|
[BP] GO:1901529 |
None
|
ABCB1, PTAFR |
2.12214 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.12214 |
|
[BP] GO:0050708 |
None
|
ACHE, CNR1, EGFR, HCAR2, HMGCR, MMP12, PPARD, PRKCA, PRKCE, SRC |
2.11677 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.11616 |
|
[BP] GO:0035588 |
None
|
ADORA1, ADORA3, PTAFR |
2.1107 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
2.10376 |
|
[BP] GO:0097190 |
apoptotic signaling pathway
|
ADORA1, BCL2, CYP1B1, POLB, PPARD, PRKCA, PRKCD, SMAD3 |
2.09193 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CNR1, CNR2, CSNK2A1, DUSP3, FABP4, GRM3, HMGCR, IGF1R, MMP9, PRKCA, PRKCD, PTGS2, PTPN1, SRC |
2.08668 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, EGFR, PRKCE, PRKCG, PTAFR |
2.0801 |
|
[BP] GO:0006066 |
None
|
AKR1B1, AKR1B10, APP, CYP1B1, CYP3A4, HMGCR, PPARD, PTAFR |
2.07273 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.05213 |
|
[BP] GO:0015844 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.05213 |
|
[BP] GO:1903959 |
None
|
ABCB1, GRM5, PTAFR |
2.05213 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.04658 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, CXCL8, EGFR, INSR, KDR, SMAD3, SRC, TRPV1 |
2.04546 |
|
[BP] GO:1903827 |
regulation of cellular protein localization
|
APP, BCL2, CHRM1, CSNK2A1, EGFR, F2, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.04546 |
|
[BP] GO:0051591 |
None
|
APEX1, APP, PTAFR, TEK, TYR |
2.03227 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.03227 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, EGFR, HCAR2, MMP12, PPARD, PRKCE, PTAFR, SRC |
2.03055 |
|
[BP] GO:0019233 |
None
|
CNR1, CNR2, GRM1, PTGS2 |
2.02086 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.02086 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.02041 |
|
[BP] GO:0016101 |
None
|
AKR1B10, CYP1A1, CYP1B1, EGFR, PPARD |
2.01484 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, HMGCR, PTAFR, PTGS1, PTGS2 |
2.01474 |
|
[BP] GO:0034762 |
None
|
ABCB1, APP, BCL2, CA2, F2, GPR35, GRM5, MMP9, PRKCE, PTAFR |
2.01474 |
|
[BP] GO:0022612 |
gland morphogenesis
|
BCL2, EGFR, POLB |
2.00375 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.00375 |
|
[BP] GO:0050995 |
None
|
ADORA1, CNR1, HCAR2 |
2.00375 |
|
[BP] GO:0050996 |
None
|
PPARA, PRKCD, PRKCE |
2.00375 |
|
[BP] GO:0071702 |
None
|
ABCB1, ADORA1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, FABP3, MMP12, PPARA, PPARD, PRKCB, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TNKS, TRPV1 |
2.00317 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, EGFR, ESR1, F10, F2, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPN1, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TRPV1 |
8.64912 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ADORA1, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, MET, PRKCG, PTGS2, SLC1A1, SLC22A1, SRC, TEK, TRPV1 |
7.64078 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALOX5, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, F10, F2, FLT3, FUT7, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TRPV1, TYR |
6.90778 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ADORA1, ADORA3, ALOX15, APP, AXL, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, DUSP3, EGFR, F10, F2, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, PRKCG, PTAFR, PTGS2, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
6.82596 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, CA4, CHRM1, CHRM2, CHRM4, CNR1, CNR2, F10, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, PTAFR, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
6.61082 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, PTAFR, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
5.86969 |
|
[CC] GO:0097060 |
None
|
CHRM1, CHRM2, CHRM4, CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, TRPV1 |
5.65924 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CHRM1, CHRM2, CHRM4, CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, PTPRS, SLC22A2, SRC, TRPV1 |
5.47652 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, IGF1R, INSR, KDR, MET, PIK3CA, PIK3CB, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TBXAS1, TEK, TRPV1, TYR |
5.2055 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, CA2, CHRM1, CHRM2, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PRKCG, PTGS2, PTPRS, SRC, TUBB3 |
4.09166 |
|
[CC] GO:0042734 |
None
|
CNR1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
3.85161 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, CA2, CHRM1, CHRM2, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, INSR, PRKCG, PTGS1, PTGS2, PTPRS, SLC22A2, SRC, TRPV1, TUBB3 |
3.36887 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
3.05338 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, F10, F2, FLT3, GRIA2, HMGCR, HSD11B1, HSD17B2, PTGS1, PTGS2, PTPN1, TBXAS1 |
2.95485 |
|
[CC] GO:0014069 |
None
|
ADORA1, CHRM1, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
2.90633 |
|
[CC] GO:0099572 |
None
|
ADORA1, CHRM1, GRIK5, GRM1, GRM3, GRM5, PRKCG, SRC |
2.90633 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, CA2, CHRM1, CHRM2, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PIK3CA, PRKCG, PTGS2, PTPRS, SRC, TEK, TUBB3 |
2.88195 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, SRC, TNKS2, TYR |
2.84033 |
|
[CC] GO:0045211 |
None
|
CHRM1, CHRM2, CHRM4, GRIA2, GRIA4, GRIK5, GRM3, TRPV1 |
2.74756 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, FLT3, GRIK5, HMGCR, HSPA1A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, XDH |
2.72901 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, CA2, CHRM1, CHRM2, CNR1, CNR2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, PIK3CA, PRKCG, PTGS2, PTPRS, SRC, TEK, TUBB3 |
2.59674 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, APP, AURKB, BCL2, CA1, CA2, CA3, CA4, CA5A, CA5B, CA7, CBR1, CDC25B, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, GRIA2, GRIA4, GRIK5, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MMP2, MMP9, NQO2, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TBXAS1, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
2.529 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, GRIA2, HMGCR, HSD11B1, HSD17B2, PTGS1, PTGS2, TBXAS1 |
2.37516 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, SLC22A1, TEK |
2.32867 |
|
[CC] GO:0043235 |
receptor complex
|
APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, SMAD3 |
2.30859 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, FLT3, FUT7, GLO1, GRIA4, GRIK5, GRM1, GRM5, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
2.09396 |
|
[CC] GO:0030054 |
cell junction
|
ACHE, AKR1B1, APP, CHRM1, CHRM2, CHRM4, EGFR, GRIA2, GRIA4, GRIK5, HCAR2, HSPA1A, KDR, PRKCD, PRKCG, PTPRS, TEK, TRPV1 |
2.04838 |
|
[CC] GO:1903561 |
None
|
ABCB1, AKR1B1, AKR1B10, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, CBR1, DUSP3, F2, FABP3, FABP4, GLO1, GRIA4, GRM5, HSPA1A, INSR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, PTPRS, SLC1A1, SLC22A2, SRC, TUBB3 |
2.04393 |
|
[CC] GO:0043230 |
None
|
ABCB1, AKR1B1, AKR1B10, ALPL, AOX1, APP, AXL, CA1, CA2, CA4, CA6, CBR1, DUSP3, F2, FABP3, FABP4, GLO1, GRIA4, GRM5, HSPA1A, INSR, MMP9, NQO2, PRKCA, PRKCB, PRKCD, PTGS1, PTPRS, SLC1A1, SLC22A2, SRC, TUBB3 |
2.04382 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PIM1, PPARA, PPARD, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
21.0249 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
17.7467 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
14.8973 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, F10, F2, FLT3, FUT7, GLO1, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
13.1601 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
11.9291 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PPARA, PPARD, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
11.3561 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.6161 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.4233 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TBXAS1, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.2995 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PPARA, PPARD, PTAFR, RORC, TEK, TRPV1 |
9.59215 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CHRM1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
8.99422 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1, POLB |
8.63304 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, HMGCR, HSD11B1, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TBXAS1, TYR, XDH |
8.56374 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PPARA, PPARD, PRKCE, PTAFR, RORC, SMAD3, TEK, TRPV1 |
8.53632 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PPARA, PPARD, PTAFR, RORC, TEK, TRPV1 |
8.37711 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PPARA, PPARD, PTAFR, RORC, TEK, TRPV1 |
8.06622 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4 |
7.44329 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.3321 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, TBXAS1, XDH |
7.30131 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, SRC, TBXAS1 |
7.17311 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, SRC, TBXAS1 |
6.87546 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS1, PTGS2, TBXAS1, TYR |
6.41427 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.26867 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.2674 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
6.21514 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, HMGCR, HSD17B1, NQO2, POLA1, PTGS1, PTGS2, SRC, TBXAS1, XDH |
6.2088 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, TBXAS1, TYR |
6.08343 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.84763 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PTAFR, TEK, TRPV1 |
5.67485 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, CHRM1, CHRM2, CHRM4, CNR1, CNR2, EGFR, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, IGF1R, INSR, KDR, MET, PTAFR, TEK, TRPV1 |
5.67485 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
5.66219 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
5.66219 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, AOX1, APP, AURKB, AXL, CSNK2A1, EGFR, F10, F2, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPRS, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
5.65924 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.52723 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.43184 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.37235 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, PPARD, RORC |
5.16751 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AOX1, AURKB, AXL, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.97761 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
4.93483 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HMGCR, HSD11B1, HSD17B1, HSD17B2, XDH |
4.88996 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.87072 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
4.82602 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
4.58649 |
|
[MF] GO:0030594 |
None
|
CHRM1, CHRM2, CHRM4, GRIA2, GRIA4, GRIK5, GRM1, GRM5 |
4.5616 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, HSD17B1, PPARA, PPARD, PTAFR, RORC, TRPV1 |
4.34708 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, GRM5, HMGCR, HSPA1A, MET, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTAFR, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
4.16066 |
|
[MF] GO:0005496 |
steroid binding
|
CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD17B1, RORC |
4.16066 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.14416 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, AOX1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.05976 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, AOX1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.05704 |
|
[MF] GO:0015238 |
None
|
ABCB1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.9311 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP3A4 |
3.88504 |
|
[MF] GO:0016907 |
None
|
CHRM1, CHRM2, CHRM4 |
3.79885 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ADORA1, APP, AURKB, AXL, CSNK2A1, EGFR, F2, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTPRS, SRC, TEK, TOP2A, TRPV1, TUBB3 |
3.61447 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.54079 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.50188 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.35031 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD17B1, HSD17B2 |
3.34842 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.31499 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, NQO2 |
3.17504 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CHRM1, CHRM2, CHRM4, CNR1, CNR2, CSNK2A1, CXCL8, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTAFR, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
3.17031 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.03521 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.03521 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.03521 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.03521 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.78948 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, GRM5, POLA1, PRKCB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.76634 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.76634 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.76634 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.76634 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.76634 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, GRM5, POLA1, PRKCB, PRKCD, PTAFR, PTPN1, SMAD3, SRC, TOP2A |
2.7425 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.6972 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.68796 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.60829 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.58108 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.52608 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.51968 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.48081 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CSNK2A1, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
2.47887 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.44978 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.44143 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP2A, TRPV1, TUBB3, XDH |
2.38222 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.37516 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.37516 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.37516 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.37516 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.37516 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.37516 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.37516 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.37516 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.37516 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.37516 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, MET, MMP9, NQO2, PTGS2, SLC22A1, SMAD3, TOP2A, TRPV1, TYR, XDH |
2.35318 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ADORA1, AOX1, APEX1, APP, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PPARD, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP2A, TRPV1, TUBB3, XDH |
2.35239 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.29853 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.29408 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CSNK2A1, DUSP3, EGFR, F10, F2, FLT3, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SRC, TEK |
2.29408 |
|
[MF] GO:0015464 |
None
|
CHRM1, CHRM2, CHRM4 |
2.22974 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PRKCB, SMAD3, SRC |
2.17839 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.16383 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.16383 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.15937 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.12214 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.12214 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.12214 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.12214 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.12214 |
