Prescription Description
| Prescription ID | TCMF3162 |
| Pinyin Name | Ban Xia Zhi Ke Tang Jiang |
| Chinese Name | 半夏止咳糖浆 |
| English Name | Ban Xia Zhi Ke Syrup |
| Function Description | 感冒 |
| Indications | Common cold disorder, Common cold |
| Disease ICD-11 Category |
SA60 [Common cold disorder (TM1), 感冒 (TM1)
]; CA00 [Acute nasopharyngitis, 急性鼻咽炎 ]; |
| Human Tissues Associated with Indication | Lung, Blood |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH130 | Pinellia ternata | 半夏 | TCMH130 | GBVT1123-13, GBVY1693-14 |
| TCMH1219 | Semen armeniacae amarum | 苦杏仁 | TCMH1219 | |
| TCMH1223 | Tussilago farfara | 款冬花 | TCMH1223 | ITSAH4326-14 |
| TCMH2728 | Aster tataricus | 紫菀 | TCMH2728 | ITSAI2445-14 |
| TCMH243 | Pericarpium citri reticulatae | 陈皮 | TCMH243 | |
| TCMH706 | Trichosanthes kirilowii | 瓜蒌皮 | TCMH706 | ITSAO4359-14 |
| TCMH1398 | Ephedra sinica | 麻黄 | TCMH1398 | ITSAM882-14 |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT107 | GRIK2 | Glutamate receptor ionotropic kainate 2 | Ion channel | Q13002 |
| TCMT109 | GRIA2 | Glutamate receptor ionotropic, AMPA 2 | Ion channel | P42262 |
| TCMT110 | GRIA4 | Glutamate receptor ionotropic, AMPA 4 | Ion channel | P48058 |
| TCMT111 | GRIK5 | Glutamate receptor ionotropic kainate 5 | Ion channel | Q16478 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
Showing 1 to 10 of 100 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1191 | Bacillus megaterium |
Showing 1 to 10 of 79 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, MMP9, SRC | 2.48397 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, SRC | 2.4863 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, APP, BCL2, CDC25B, FABP4, FLT3, GRM1, GRM5, IGF1R, KDR, MIF, MMP9, PTPN1, SRC, XDH | 2.33417 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, APP, BCL2, CDC25B, FLT3, GRM1, GRM5, KDR, MIF, MMP9, PTPN1, SRC, XDH | 2.70669 |
| [BP] GO:0006145 | None | AOX1, XDH | 2.19453 |
| [BP] GO:0006468 | protein phosphorylation | APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, FLT3, IGF1R, KDR, MET, PIM1, SRC, TNKS | 3.3284 |
| [BP] GO:0006629 | lipid metabolic process | ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, ESR1, FABP3, FABP4, FUT7, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, MIF, PPARA | 8.5905 |
| [BP] GO:0006631 | fatty acid metabolic process | ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, MIF, PPARA | 2.94291 |
| [BP] GO:0006690 | icosanoid metabolic process | ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, MIF | 3.47784 |
| [BP] GO:0006694 | steroid biosynthetic process | AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 | 3.10776 |
Showing 1 to 10 of 258 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, PIM1 | 1.3247 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MET, IGF1R | 4.215 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5488 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2 | 0.3851 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1, F3 | 2.6275 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2 | 0.7093 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP | 0.3537 |
| Amphetamine addiction_Homo sapiens_hsa05031 | GRIA2, GRIA4 | 1.2549 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | IGF1R | 0.4264 |
| Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | GRIA2, BCL2 | 1.3868 |
Showing 1 to 10 of 144 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples