| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS1, PTGS2, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, XDH |
20.7519 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HTR1B, HTR5A, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PRKCB, PRKCD, PRKCE, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
18.4004 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
18.0226 |
|
[BP] GO:0042221 |
response to chemical
|
ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GRIK5, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
17.7158 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
16.1236 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
16.0817 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.871 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.871 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FLT3, HSD11B2, HTR1B, HTR5A, NR3C1, PRKCE, PRKCG, PTGES, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
14.5004 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRA1A, CNR1, CNR2, DRD1, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7 |
14.1294 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
13.7348 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
13.4952 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
13.4952 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
13.2984 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
12.8535 |
|
[BP] GO:0042493 |
response to drug
|
ADRA1A, AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, FABP3, HMGCR, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KDR, NR3C1, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TRPV1 |
12.6509 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADRA1A, APP, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, PRKCE, PTGS2 |
12.5551 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADRA1A, APP, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, PRKCE, PTGS2 |
12.5551 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRA1A, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CDK6, CNR1, CNR2, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
12.4362 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, AKR1B1, APP, AR, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PGR, PIM1, PRKCA, PTGES, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
12.0018 |
|
[BP] GO:0007193 |
None
|
ADORA1, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
11.9851 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA1A, AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, GRM5, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, MMP2, NR3C1, PPARA, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1 |
11.8988 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD1, DRD2, EGFR, GRM1, GRM3, GRM5, GRM8, HTR1B, HTR2A, PTGS2 |
11.8945 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
11.8945 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.8793 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MET, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
11.8557 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, GRM1, GRM3, GRM5, GRM8, HMGCR, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
11.7732 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2, TRPV1 |
11.7706 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, CNR1, DRD1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, KDR, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
11.7441 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRA1A, CNR1, DRD1, DRD2, DRD3, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7 |
11.7441 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA1A, AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, INSR, NR3C1, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK, TRPV1 |
11.3191 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TRPV1 |
11.3191 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, HTR1B, HTR5A, NR3C1, PRKCE, PTGES, PTGS2, RORC, SRC, TYR |
11.2887 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
11.2376 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
10.9853 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GRIK5, GRM1, GRM5, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, TYR |
10.8558 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
10.8493 |
|
[BP] GO:0097756 |
None
|
ADORA1, ADRA1A, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
10.776 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, TYR |
10.7711 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
10.6854 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.6646 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.6646 |
|
[BP] GO:0099536 |
None
|
CNR1, DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
10.6544 |
|
[BP] GO:0099537 |
None
|
CNR1, DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
10.6544 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, GRIK5, HCAR2, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
10.4554 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.2483 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRA1A, AR, AXL, BCL2, CNR1, DRD1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, PRKCG, PTGS2, SLC1A1, TEK, TRPV1 |
10.2115 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, PRKCG, SLC1A1, TEK |
10.1544 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ADRA1A, AKR1B1, APP, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
10.1161 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, ADRA1A, CA2, CA7, CNR1, CNR2, DRD2, HTR1B, PRKCE |
9.97161 |
|
[BP] GO:0007268 |
None
|
DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
9.79682 |
|
[BP] GO:0098916 |
None
|
DRD1, DRD2, DRD3, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PRKCG, SLC1A1 |
9.79682 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, ADRA1A, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, SRC, TRPV1 |
9.64148 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.62782 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
9.60489 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.59676 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HTR1B, IGF1R, INSR, KDR, MMP2, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
9.55782 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.50437 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR2B, HTR2C, PIK3CA, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR, XDH |
9.4718 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
9.44696 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRA1A, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SRC, TEK |
9.4424 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CNR1, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, HTR2C, PRKCA, PRKCE, SLC22A1 |
9.40861 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA1A, ALOX15, APP, AR, DRD2, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
9.38113 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.38113 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.36196 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM5, HSPA1A, HTR1B, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
9.32528 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
9.2325 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD1, DRD2, DRD3, ESR2, GRIA2, GRIK5, GRM1, GRM3, GRM5, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, PGR, PRKCG, SLC1A1, TEK |
9.23164 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
9.13103 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CNR1, CYP19A1, DRD1, DRD2, DRD3, EGFR, GPR35, GRIK5, GRM5, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, MMP12, MMP9, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TRPV1 |
9.11895 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.04285 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA1A, ALOX15, APP, AR, DRD2, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
8.98676 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRA1A, APP, CA2, CNR1, CNR2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, PIK3CA, PIK3CB, SIGMAR1, SRC |
8.97382 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.95029 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
8.92532 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PRKCA, PTGS2, TEK |
8.58856 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, HMGCR, HTR1B, HTR1D, KDR, PRKCD, PRKCE, SRC |
8.57719 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CDK6, CYP1B1, DRD1, EGFR, ESR1, GRIK5, GRM5, IGF1R, INSR, MMP2, MMP9, NR3C1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TRPV1 |
8.56106 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.55306 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, GRM5, HSD11B2, HTR1B, IGF1R, INSR, MMP2, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
8.55306 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
8.42977 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CNR1, CYP1A1, DRD3, FABP3, FLT3, HCAR2, HMGCR, HTR2A, HTR2B, HTR2C, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
8.3837 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
8.38172 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.37238 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.32316 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
8.32316 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRA1A, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
8.30619 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRA1A, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
8.30619 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.25561 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD1, DRD2, DRD3, EGFR, GRM1, GRM5, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
8.15934 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, GRM1, HMGCR, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1, TYR |
8.1462 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRA1A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM3, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
8.14099 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
8.09565 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.085 |
|
[BP] GO:0050801 |
ion homeostasis
|
ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, FABP3, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
8.0746 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
8.0746 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRA1A, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
8.0224 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRA1A, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
7.98699 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRA1A, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2, SRC, TEK |
7.97858 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.96864 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, HTR2A, HTR2B, HTR2C, KDR, PRKCE, SRC, TRPV1 |
7.90219 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
7.90219 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.89779 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, HTR1D, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
7.86724 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.81464 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRIK5, HTR1A, INSR, PTGS2, SLC1A1, SLC22A2, SLC22A3, SMAD3, TRPV1 |
7.7816 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, PRKCD, PTGES, PTGS2, SRC |
7.66176 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ADRA1A, APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.64888 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, HTR2A, HTR2B, HTR2C, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
7.62215 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HCAR2, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
7.55494 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MMP9, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.52604 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.52604 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.52604 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRA1A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GRM1, GRM3, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TRPV1, XDH |
7.50664 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
7.43693 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, DUSP3, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, PRKCA, PTPN1, SRC, TEK |
7.38362 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, PRKCD, SRC, TEK |
7.38095 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
7.38051 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
7.37363 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
7.37363 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRA1A, AKR1B1, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GRM1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.3275 |
|
[BP] GO:0007215 |
None
|
APP, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.31274 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, PTGS1, PTGS2 |
7.29502 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, HTR1B, KDR, NR3C1, PRKCD, PRKCE, PTGS2, SRC, TRPV1 |
7.23482 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
7.22506 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.20665 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.20665 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, MET, PIK3CA, PIK3CB, PPARA, PTGES, PTGS1, PTGS2 |
7.20164 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ADRA1A, ALOX15, APP, DRD2, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, PRKCA, SRC, TEK |
7.195 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
7.16914 |
|
[BP] GO:0042310 |
None
|
ADRA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
7.14463 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
7.11272 |
|
[BP] GO:0055080 |
cation homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.09374 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
7.07931 |
|
[BP] GO:0006939 |
None
|
ADRA1A, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, TRPV1 |
7.02903 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRA1A, AKR1B1, APP, BCL2, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRM1, GRM5, GRM8, HMGCR, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, PIK3CA, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
7.02903 |
|
[BP] GO:0006811 |
None
|
ADRA1A, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, FABP3, GRIA2, GRIA4, GRIK5, HTR2A, HTR2B, HTR2C, PPARA, PRKCB, PRKCE, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
7.02903 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
6.9994 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.98529 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ADRA1A, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.91583 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
6.86342 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ADRA1A, APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, DRD3, ESR1, GPR35, GRIK5, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.84758 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, FABP4, GPR35, GRM3, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
6.82218 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.8098 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.70615 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD2, DRD3, GPR35, HTR1B, HTR2A, MMP9, PRKCE, PTGS2 |
6.6462 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC22A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
6.61728 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA1A, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, KDR, MET, MMP12, MMP9, PIM1, PRKCA, PRKCB, PRKCE, PTGS2, SLC1A1, SMAD3, SRC, TEK, TRPV1 |
6.61637 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, MET, MMP2, MMP9, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
6.60647 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
6.59384 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, EGFR, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.59384 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ADRA1A, APP, BCL2, DRD1, DRD2, DRD3, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
6.58048 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA1A, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
6.56886 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA1A, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
6.54045 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
6.53228 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.52666 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
6.50999 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, GRIK5, GRM1, GRM5, HSPA1A, HTR1B, IGF1R, INSR, KDR, MMP2, MMP9, NR3C1, NUAK1, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
6.47774 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD2, DRD3, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
6.4234 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.36893 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRA1A, ALOX15, AR, BCL2, CDK6, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.36593 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
6.31893 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, HTR7, PGR, PPARA, PRKCG, RORC, SRC, TOP2A |
6.31231 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
6.26983 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRA1A, APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, GRM1, HCAR2, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, SLC1A1, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
6.24086 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, HMGCR, KDR, MET, MMP12, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, SMAD3, TEK |
6.20286 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.20286 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADRA1A, APP, CA2, CA7, DRD1, DRD2, EGFR, PRKCE, PTGS2 |
6.19662 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
6.16411 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, PPARA, PTGES, PTGS1, PTGS2 |
6.1079 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD1, DRD2, HTR1B, HTR2A, PTGS2 |
6.09446 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.09414 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, NR3C1, PTGS2, RORC, SRC, TRPV1 |
6.06884 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.99819 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.96351 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
5.95023 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.88097 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.87737 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, DRD1, EGFR, ESR1, FLT3, GRM5, HTR1B, IGF1R, INSR, MMP2, NR3C1, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
5.81472 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRA1A, ALOX15, DRD1, EGFR, HMGCR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PRKCD, PRKCE, PTGS2 |
5.79628 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.78902 |
|
[BP] GO:1900543 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PPARA, PRKCA |
5.75525 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
5.75406 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.74113 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
5.71762 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, PRKCD, SRC, TEK |
5.71762 |
|
[BP] GO:0045980 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PPARA, PRKCA |
5.71762 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MET, MMP12, MMP9, NR3C1, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
5.70035 |
|
[BP] GO:0030815 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
5.66562 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CNR1, DRD1, DRD2, DRD3, EGFR, GRM5, HMGCR, HTR2A, INSR, PRKCG, PTGS2 |
5.65862 |
|
[BP] GO:0030800 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
5.54324 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GRM1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.52602 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, HTR1B, NR3C1, PRKCE, PRKCG |
5.47276 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, DRD3, ESRRB, GRM3, GRM8, HTR1B, HTR1E, HTR2A, INSR, PPARA, PRKCA |
5.45213 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.45213 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD1, DRD2, DRD3, EGFR, GRM5, HMGCR, HTR2A, INSR, PRKCG, PTGS2 |
5.43509 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, GRM1, GRM5, HTR2A, HTR2B, HTR2C, PRKCE, SMAD3, TRPV1 |
5.43406 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
5.41624 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRA1A, APP, AR, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F3, FLT3, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, MET, MMP9, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
5.40825 |
|
[BP] GO:0042391 |
None
|
ADORA1, ADRA1A, APP, BCL2, CNR1, CNR2, DRD1, GPR35, GRIA2, GRIA4, GRIK5, GRM5, KDR, SRC, TRPV1 |
5.37892 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP12, PRKCA, PRKCE, SRC, TRPV1 |
5.3483 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK |
5.34014 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, DRD3, ESRRB, GRM3, GRM8, HTR1B, HTR1E, HTR2A, INSR, PPARA, PRKCA |
5.33026 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
5.32903 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.31476 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.31476 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, PRKCG, SRC, TEK |
5.29838 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GRM5, HSD11B2, IGF1R, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
5.29246 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
5.2315 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, GBA2, HMGCR, HTR1A, TYR |
5.20388 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, APP, BCL2, CA2, CA7, CNR1, DRD1, DRD2, DRD3, GPR35, GRM5, HTR1A, HTR1B, HTR2A, MMP9, PRKCD, PRKCE, PTGS2 |
5.20228 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PPARA, PTGES, PTGS1, PTGS2 |
5.17198 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, DRD3, EGFR, GRIK5, HCAR2, HMGCR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP12, PRKCA, PRKCE, SRC |
5.17198 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
5.13985 |
|
[BP] GO:0007200 |
None
|
ADRA1A, DRD1, DRD2, ESR1, GRM5, HTR2A, HTR2B, HTR2C |
5.1242 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
5.07847 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
5.01895 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
5.01381 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.96193 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CNR1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A, HTR2A, HTR2C, PRKCA, PRKCE |
4.95067 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, ADRA1A, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PIK3CA, PPARA, SMAD3, SRC, TEK, TYR |
4.9452 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, GRM1, GRM5, HMGCR, HTR2A, HTR2B, IGF1R, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.87292 |
|
[BP] GO:0060402 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.84537 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTGS2, SRC |
4.84308 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.82998 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.82437 |
|
[BP] GO:0007196 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.8074 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.8074 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, F10, FLT3, IGF1R, INSR, KDR, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS, TOP2A |
4.79325 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
ADRA1A, BCL2, DRD2, DRD3, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PRKCD, PTGS2, PTPN1, SRC, XDH |
4.75414 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRA1A, DRD2, DRD3, EGFR, GPR35, GRM1, HCAR2, HTR2A, HTR2C, PRKCA, PTGS2, SLC1A1, SMAD3, TRPV1 |
4.73311 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
4.73284 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, HTR2C, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.69409 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, GRM5, HTR1B, IGF1R, INSR, MMP2, PRKCD, PTGS2, SRC, TRPV1 |
4.68469 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
4.61137 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA1A, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, GRM1, GRM5, HSPA1A, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.60995 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.59253 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
4.58411 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.5738 |
|
[BP] GO:0030818 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.56432 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA1A, AKR1B1, AXL, BCL2, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRM5, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
4.54298 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.51399 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.51164 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.51164 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.49959 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DRD2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.49753 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.483 |
|
[BP] GO:0030803 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.4603 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.45323 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.4497 |
|
[BP] GO:0002031 |
None
|
DRD2, DRD3, HTR1B, HTR2B |
4.43266 |
|
[BP] GO:0019371 |
None
|
CBR1, PTGES, PTGS1, PTGS2 |
4.43266 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2 |
4.40161 |
|
[BP] GO:0051952 |
None
|
ADORA1, CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A |
4.38206 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTGS2 |
4.38206 |
|
[BP] GO:0060401 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.38206 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
ADRA1A, DRD1, DRD2, ESR1, GPR35, GRM1, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.35938 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, HTR1A, TYR |
4.31318 |
|
[BP] GO:1900372 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.31318 |
|
[BP] GO:0030809 |
None
|
DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
4.31318 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HMGCR, HSPA1A, HTR1B, HTR1E, IGF1R, MMP12, MMP9, NR3C1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
4.31318 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, GRM5, HTR1B, IGF1R, INSR, MMP2, PRKCD, PTGS2, SRC, TRPV1 |
4.31307 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.29926 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTGS2, SRC |
4.29926 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, NQO2, PTGS1, RORC |
4.29765 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD2, DRD3, GPR35, HMGCR, HSPA1A, HTR1B, HTR2A, MMP9, PRKCB, PRKCE, PTGS2 |
4.29615 |
|
[BP] GO:0015872 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
4.28165 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.26599 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, PRKCA, PRKCE, SRC |
4.24774 |
|
[BP] GO:0030814 |
None
|
DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
4.24653 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.23549 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, DRD1, PRKCA, PRKCB, PRKCD |
4.22899 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD2, DRD3, HTR1B, HTR2A |
4.22899 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, HCAR2, HTR2B, INSR, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
4.2021 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, HTR2A, MET, PIK3CA, TRPV1 |
4.19641 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PPARA, PRKCD, PRKCE |
4.17702 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.17362 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, HSD11B2, HSPA1A, HTR1A, HTR2C, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1 |
4.16851 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGES, PTGS2 |
4.15276 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MET, PIK3CA, PPARA, PRKCG, SMAD3 |
4.14463 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
ADRA1A, CA2, CA7, PRKCE |
4.14463 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, GRM1, GRM5, HTR2A, HTR2B, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
4.12608 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TNKS, TOP2A |
4.11315 |
|
[BP] GO:0035265 |
organ growth
|
ADRA1A, AR, BCL2, CYP19A1, ESR1 |
4.08979 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
4.08475 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
4.07531 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
4.07384 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, HTR2C, MMP12, PRKCA, PRKCE, SRC |
4.06993 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, HTR5A, INSR, KDR, MMP9, PGR, PIK3CA, PIM1, PPARA, PTGS2, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
4.0679 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
4.02901 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, HTR2A, TRPV1 |
4.02593 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
4.02593 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
4.02593 |
|
[BP] GO:0050678 |
None
|
AR, CDK6, EGFR, F3, HTR2B, KDR, MMP12, PGR, PRKCA, SMAD3, TEK, XDH |
4.02145 |
|
[BP] GO:0007216 |
None
|
GRM1, GRM3, GRM5, GRM8 |
4.02145 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR1B, HTR2A |
4.02145 |
|
[BP] GO:0060359 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR1B, PRKCE, PRKCG |
4.0068 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, EGFR, HSPA1A |
4.00349 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, MMP12, PPARA, PRKCD, SMAD3, TEK |
3.99189 |
|
[BP] GO:2001023 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR1B, HTR2A, MET |
3.9771 |
|
[BP] GO:0097553 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.97419 |
|
[BP] GO:0072347 |
None
|
CNR1, DRD2, DRD3, HTR1B, PRKCE, PRKCG |
3.97419 |
|
[BP] GO:0043278 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
3.96935 |
|
[BP] GO:0014072 |
None
|
CNR1, DRD2, DRD3, PRKCE, PRKCG |
3.96935 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRA1A, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.95244 |
|
[BP] GO:0051588 |
None
|
DRD1, DRD2, DRD3, GRIK5, HTR1A, HTR1B, HTR2C |
3.95244 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
3.95244 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.94101 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
3.94101 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, DRD1, DRD2, DRD3, HMGCR, PPARA, PRKCD, SMAD3, TEK |
3.93258 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.93217 |
|
[BP] GO:0043279 |
None
|
CNR1, DRD2, DRD3, HTR1B, PRKCE, PRKCG, TRPV1 |
3.92575 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.91176 |
|
[BP] GO:0051937 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.91103 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.89434 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.88266 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.86849 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, EGFR, PPARA, SMAD3 |
3.85282 |
|
[BP] GO:0071502 |
None
|
HTR1B, HTR2B, TRPV1 |
3.83758 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.83758 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, GRM5, HTR2A, PRKCD, PRKCE, PTPN1, SRC |
3.83758 |
|
[BP] GO:0007568 |
aging
|
ADRA1A, APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, HTR2A, PRKCD, PTGS2 |
3.83758 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.82812 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.80533 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
3.80533 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.80533 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, GRM5, HMGCR, INSR, PTGS2 |
3.8029 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.80131 |
|
[BP] GO:0008150 |
biological_process
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.76124 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.74507 |
|
[BP] GO:0030817 |
None
|
DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
3.74113 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, PRKCG, RORC, TOP2A |
3.74113 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
3.72094 |
|
[BP] GO:0006855 |
None
|
SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.72094 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, RORC, SMAD3, SRC, TRPV1 |
3.72094 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
3.70518 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
3.69376 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, PTGES, PTGS1, PTGS2 |
3.69376 |
|
[BP] GO:0030799 |
None
|
DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, HTR1E, PRKCA |
3.68109 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, PRKCA |
3.63698 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
3.61177 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.60825 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR1D, HTR2B |
3.60806 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, GRM1, HMGCR, HTR2A, HTR2B, IGF1R, INSR, PIK3CB, PRKCD, PTPN1, SRC |
3.60627 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, EGFR, GRM1, GRM5, GRM8, HMGCR, HTR2A, INSR, PRKCG, PTGS2, TRPV1, TYR |
3.6059 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
3.60419 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, MET, PIK3CB, PIM1, PRKCD, SRC, TEK, TYR |
3.58114 |
|
[BP] GO:0045913 |
None
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, SRC |
3.58114 |
|
[BP] GO:0032229 |
None
|
ADORA1, CNR2, HTR1B |
3.57609 |
|
[BP] GO:0015893 |
None
|
CA2, DRD1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.56005 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TNKS, TOP2A |
3.54765 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CNR1, CYP1B1, F3, GRIK5, HCAR2, HMGCR, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.53013 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.51049 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.48969 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.48969 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.48969 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
3.48969 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CDK6, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, SMAD3, SRC, TEK |
3.47067 |
|
[BP] GO:0045936 |
None
|
DRD2, DRD3, DUSP3, FABP4, GRM3, GRM8, HMGCR, HTR1B, HTR1E, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
3.47067 |
|
[BP] GO:0010563 |
None
|
DRD2, DRD3, DUSP3, FABP4, GRM3, GRM8, HMGCR, HTR1B, HTR1E, IGF1R, PPARA, PRKCA, PRKCD, PTPN1, XDH |
3.46487 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, HTR2B, MMP12, PRKCE, SRC, TRPV1 |
3.45712 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA1A, AR, BCL2, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PRKCB, PRKCD, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.45712 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, DRD3, PPARA |
3.44486 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.44461 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3, HTR2A |
3.43984 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.43981 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.39524 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, PIK3CB, PTPN1, SRC |
3.38612 |
|
[BP] GO:0003012 |
None
|
ADORA1, ADRA1A, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
3.38612 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.3773 |
|
[BP] GO:0051282 |
None
|
DRD1, DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.3773 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.36358 |
|
[BP] GO:0015844 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.35983 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.35494 |
|
[BP] GO:0051234 |
None
|
ACHE, ADORA1, ADRA1A, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, EGFR, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
3.35262 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, PRKCD, SMAD3, TEK |
3.33375 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CNR1, CSNK2A1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.32605 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.3163 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CDK6, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, HTR2A, HTR2C, INSR, KDR, NUAK1, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
3.31237 |
|
[BP] GO:0060078 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, GRM5, TRPV1 |
3.30596 |
|
[BP] GO:0006936 |
None
|
ADRA1A, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
3.30279 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.30182 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
3.29946 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD, TNKS |
3.27811 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, NR3C1, PGR, SRC |
3.27811 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MMP12, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.25085 |
|
[BP] GO:0030802 |
None
|
DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
3.2465 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
3.24553 |
|
[BP] GO:0006810 |
None
|
ACHE, ADORA1, ADRA1A, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TRPV1, XDH |
3.2408 |
|
[BP] GO:0050433 |
None
|
CNR1, DRD2, DRD3, HTR1B, HTR2A |
3.23013 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.23013 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PRKCD, PRKCE |
3.22728 |
|
[BP] GO:0051179 |
None
|
ACHE, ADORA1, ADRA1A, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, DRD3, EGFR, ESR1, F10, FABP3, GRIA2, GRIA4, GRIK5, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, MMP12, MMP9, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TNKS, TNKS2, TRPV1, XDH |
3.22221 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
3.21597 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, DRD2, DRD3, ESR1, ESR2, ESRRA, FABP4, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, MMP12, NR3C1, PPARA, PRKCA, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1 |
3.19466 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, PRKCE, SRC |
3.19339 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
3.19003 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TNKS |
3.19003 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.19003 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.19003 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.14999 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.14815 |
|
[BP] GO:0007202 |
None
|
ADRA1A, EGFR, HTR2A, HTR2B |
3.14815 |
|
[BP] GO:0032098 |
None
|
HTR2C, HTR4, PPARA, SLC22A3 |
3.14815 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HMGCR, PTGS2, TYR |
3.13339 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR, HMGCR |
3.125 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, HTR2B, PRKCE |
3.11314 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.10424 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, F3, HTR2B, KDR, MMP12, PRKCA, TEK |
3.09172 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, MMP2, MMP9, PGR, PTGS2, SRC, TOP2A |
3.08817 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, PRKCA, PRKCB, PRKCD, TNKS |
3.08713 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, HMGCR, HTR2A, HTR2C, INSR, KDR, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK |
3.07704 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, HTR1B, MMP2, MMP9, PTGS2 |
3.06505 |
|
[BP] GO:0050708 |
None
|
ACHE, CNR1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR2B, MMP12, PRKCA, PRKCE, SRC |
3.05887 |
|
[BP] GO:1900371 |
None
|
DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
3.0454 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, PRKCE, SRC |
3.0454 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.0388 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PRKCE, SRC |
3.0388 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, DRD3, GRM1, GRM5, HTR2C, PRKCE |
3.03386 |
|
[BP] GO:0030808 |
None
|
DRD1, DRD2, DRD3, GRM3, GRM8, HTR1B, PRKCA |
3.03083 |
|
[BP] GO:0035235 |
None
|
APP, GRIA2, GRIA4, GRIK5 |
3.0246 |
|
[BP] GO:0001975 |
None
|
CNR2, DRD1, DRD2, DRD3 |
3.0246 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRA1A, DRD1, DRD2, DRD3, EGFR, GRM5, HTR2B, HTR5A, KDR |
3.02274 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
3.00731 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
2.99351 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, DRD3, HTR1A |
2.98953 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
BCL2, DRD1, HTR1A, HTR2C, PRKCG |
2.96986 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
2.9621 |
|
[BP] GO:0031623 |
None
|
ACHE, DRD2, DRD3, HTR1B, HTR2B |
2.9332 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.93079 |
|
[BP] GO:0032409 |
None
|
APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCD, PRKCE |
2.93079 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, HCAR2, HTR2B, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
2.91034 |
|
[BP] GO:0051482 |
None
|
DRD1, GPR35, GRM1, HTR2C |
2.90349 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
CA2, CA7, GRM5 |
2.89983 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.89983 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ADRA1A, ALPL, AXL, BCL2, CDK6, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, HMGCR, HSD11B2, HTR2A, MMP12, PRKCD, PTGES, PTGS2, SMAD3, SRC, TRPV1, TYR |
2.89842 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MET, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
2.87107 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.86701 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTGS2 |
2.86494 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PGR, PTGS2, SRC |
2.85731 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX15, PTGES, PTGS1, PTGS2 |
2.85174 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.84846 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, PTGS2, TRPV1, TYR |
2.82616 |
|
[BP] GO:0003014 |
None
|
ADORA1, ADRA1A, AKR1B1, BCL2, DRD2, HSD11B2 |
2.82511 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, GRM1, INSR, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.81951 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.80348 |
|
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.79892 |
|
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.79892 |
|
[BP] GO:0051302 |
None
|
AURKB, CDC25B, DRD2, DRD3, ESRRB, HTR2B, PRKCE |
2.79693 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.79693 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DRD2, DRD3, EGFR, ESR1, ESR2, GRIK5, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.79693 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.79403 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.79403 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.79403 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.79054 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, HTR2B, MMP12, PRKCE, SRC |
2.78441 |
|
[BP] GO:0042220 |
None
|
CNR1, DRD2, DRD3, HTR1B |
2.75429 |
|
[BP] GO:0045777 |
None
|
ADORA1, ADRA1A, CNR1, HSD11B2 |
2.75429 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.74933 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.74933 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTGES, PTGS2, SRC |
2.74691 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.72397 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.72397 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.72397 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.72397 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.72174 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.72174 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, APP, AR, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, PTGES, PTGS2, SMAD3, XDH |
2.72174 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GRM3, GRM5, GRM8, HMGCR, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.71859 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, PTGS1, PTGS2, TYR |
2.71859 |
|
[BP] GO:0007194 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.71054 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.71054 |
|
[BP] GO:0042596 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.71054 |
|
[BP] GO:0009266 |
None
|
ADORA1, HSPA1A, HTR1B, HTR2A, HTR2B, PTGS2, TRPV1 |
2.68946 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.6872 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.6872 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC |
2.67752 |
|
[BP] GO:0043086 |
negative regulation of catalytic activity
|
APP, CNR1, CNR2, CSNK2A1, DRD2, DRD3, DUSP3, FABP4, GRM3, HMGCR, IGF1R, MMP9, PRKCA, PRKCD, PTGS2, PTPN1, SRC |
2.67132 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, DRD2, F10, F3, MET, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
2.66696 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.66694 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.66616 |
|
[BP] GO:0045907 |
None
|
ADRA1A, EGFR, HTR2A, PTGS2 |
2.66616 |
|
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, PTGS2 |
2.64599 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AR, AXL, BCL2, CBR1, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HTR2B, KDR, MET, MMP2, MMP9, PGR, PRKCD, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A |
2.64599 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GRM5, IGF1R, INSR, PRKCD, SRC |
2.639 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK |
2.6288 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, PRKCE, TNKS |
2.6286 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, KDR, PRKCE, SMAD3, TEK |
2.62622 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TRPV1, TYR |
2.62591 |
|
[BP] GO:0031280 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.61975 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, DRD2, EGFR, HCAR2, HTR2B, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
2.60965 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.60703 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.59118 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.59118 |
|
[BP] GO:0001516 |
None
|
PTGES, PTGS1, PTGS2 |
2.59118 |
|
[BP] GO:0046457 |
None
|
PTGES, PTGS1, PTGS2 |
2.59118 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.58536 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, PRKCE |
2.5805 |
|
[BP] GO:0032465 |
None
|
AURKB, CDC25B, DRD2, DRD3, PRKCE |
2.55584 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
APEX1, AR, EGFR, ESR1, FLT3, INSR, NR3C1, PRKCD, PRKCE, SRC |
2.55191 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
2.55191 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, PTGS2, SRC |
2.54715 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, CDK6, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, NUAK1, PRKCD, PRKCG, PTGS2, PTPN1, XDH |
2.54436 |
|
[BP] GO:0051350 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.53227 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR |
2.53031 |
|
[BP] GO:0060079 |
None
|
ADORA1, GRIA2, GRIA4, GRIK5, TRPV1 |
2.53031 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, KDR, MET, PRKCA, PTGS2, SMAD3 |
2.52679 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, AR, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HSPA1A, INSR, PIK3CA, PIM1, SMAD3, TNKS2 |
2.51962 |
|
[BP] GO:1903524 |
None
|
ADRA1A, EGFR, HTR2A, PTGS2, SLC1A1 |
2.50245 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PRKCG, PTPN1, SRC |
2.5024 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.50038 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.50038 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.49556 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, GRM1, HTR2A, HTR2B, INSR, PIK3CB, PTPN1, SRC |
2.47947 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
2.47848 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.45082 |
|
[BP] GO:0014075 |
None
|
CNR2, DRD1, DRD2, DRD3 |
2.45033 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.45033 |
|
[BP] GO:0046890 |
None
|
FABP3, HMGCR, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
2.43505 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, CDK6, EGFR, ESR1, FLT3, NR3C1, PRKCE, RORC, SRC |
2.43455 |
|
[BP] GO:0050965 |
None
|
ADORA1, HTR2A, TRPV1 |
2.41508 |
|
[BP] GO:0050961 |
None
|
ADORA1, HTR2A, TRPV1 |
2.41508 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3 |
2.41508 |
|
[BP] GO:0038128 |
None
|
EGFR, PIK3CA, PRKCA, SRC |
2.40956 |
|
[BP] GO:0071383 |
None
|
AR, EGFR, FLT3, NR3C1, SRC |
2.4002 |
|
[BP] GO:0022898 |
None
|
APP, BCL2, DRD2, DRD3, GPR35, GRM5, MMP9, PRKCE |
2.39482 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, PIK3CA, PIK3CB, PTGES, PTGS1, PTGS2, TRPV1 |
2.39042 |
|
[BP] GO:0099566 |
None
|
GRM1, GRM5 |
2.39042 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.39042 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.39042 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.39042 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.39042 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.39042 |
|
[BP] GO:0032413 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.38506 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.37258 |
|
[BP] GO:0098657 |
import into cell
|
ACHE, ADORA1, ALOX15, APP, AXL, DRD2, DRD3, HTR1B, HTR2B, SLC1A1, SLC22A3, TRPV1 |
2.36376 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, PTGS2, SRC |
2.36172 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PRKCE, RORC, SRC |
2.35346 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.34726 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.34726 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.34726 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.34726 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, RORC, SRC |
2.34726 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK |
2.33248 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, HCAR2, HTR2B, MMP12, PRKCE, SRC |
2.32346 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PRKCD, PRKCE, PTPN1 |
2.31512 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, HTR5A, PTGS2 |
2.30094 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.27939 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.27149 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.27149 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.26942 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.26942 |
|
[BP] GO:1901570 |
None
|
ALOX15, ALOX5, PTGES, PTGS1, PTGS2 |
2.2671 |
|
[BP] GO:0006816 |
None
|
ADRA1A, DRD2, HTR2A, HTR2B, HTR2C, PRKCB, PRKCE, TRPV1 |
2.25616 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GRM3, GRM5, GRM8, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.2527 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B |
2.23335 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, GRM3, GRM8, HSPA1A, HTR1B, HTR1E, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, NR3C2, PGR, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
2.22492 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
APP, AR, BCL2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, GRIK5, HMGCR, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.22346 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ADORA1, CA2, CA7, GRM5, PRKCD |
2.22222 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.22222 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.22222 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
APP, AR, BCL2, DRD2, DRD3, INSR, PIK3CA, PIM1, TNKS2 |
2.21948 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, INSR, KDR, NR3C1, SMAD3, SRC, TRPV1 |
2.2137 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.20501 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.20501 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.20501 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC |
2.20489 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PTGS2, TEK, TRPV1, TYR |
2.20489 |
|
[BP] GO:0045761 |
None
|
DRD2, DRD3, GRM3, PRKCA |
2.20489 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.20489 |
|
[BP] GO:0097366 |
None
|
CNR2, DRD1, DRD2, DRD3 |
2.20489 |
|
[BP] GO:0032410 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.20489 |
|
[BP] GO:1904063 |
None
|
DRD2, DRD3, GPR35, MMP9, PRKCE |
2.20489 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
2.17642 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, KDR, MMP12, MMP9, NR3C1, PGR, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
2.17361 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.15943 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.15943 |
|
[BP] GO:0001936 |
None
|
F3, HTR2B, KDR, PRKCA, TEK, XDH |
2.15765 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.14403 |
|
[BP] GO:0016048 |
None
|
ADORA1, HTR2A, TRPV1 |
2.14403 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.14403 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.14403 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, DRD1, EGFR, ESR1, PGR, PTGS2, SRC |
2.14179 |
|
[BP] GO:0001938 |
None
|
F3, HTR2B, KDR, PRKCA, TEK |
2.14109 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.13476 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.13476 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.13476 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.13476 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.13476 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.13476 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.13476 |
|
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.13476 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, EGFR, HTR7, PPARA, RORC |
2.11723 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.10753 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.08739 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.08114 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, MET, PIK3CA, PIK3CB |
2.05564 |
|
[BP] GO:0030534 |
None
|
APP, DRD1, DRD2, DRD3, HTR2A, PPARA |
2.05469 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PTGS2, SRC, TEK |
2.05204 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CNR1, CNR2, CYP19A1, DRD2, DUSP3, MMP12 |
2.04201 |
|
[BP] GO:0019933 |
None
|
ADRA1A, DRD1, DRD2, DRD3, HTR5A |
2.04201 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.03 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.02947 |
|
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.02947 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.02947 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DRD2, DUSP3, ESR1, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC |
2.0151 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.0151 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.0151 |
|
[BP] GO:0061041 |
regulation of wound healing
|
F3, HMGCR, PRKCA, PRKCD, PRKCE, SMAD3 |
2.01279 |
|
[BP] GO:0090276 |
None
|
CNR1, DRD2, EGFR, HMGCR, HTR2C, PRKCA, PRKCE |
2.0012 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, APP, AXL, CA4, CNR1, CNR2, DRD1, DRD2, DRD3, F10, F3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
13.4944 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TRPV1 |
12.8593 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP2, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, TYR |
11.9636 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, APP, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, FLT3, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
11.9636 |
|
[CC] GO:0044459 |
plasma membrane part
|
ADORA1, ADORA3, ADRA1A, ALOX15, APP, AXL, CA2, CA4, CA9, CNR1, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, F10, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PRKCG, PTGS2, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
11.0994 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ADRA1A, ALOX15, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C2, PIK3CA, PIK3CB, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SRC, TEK, TRPV1, TYR |
8.7982 |
|
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, ADRA1A, CA2, CA4, CA9, CNR1, DRD1, DRD2, EGFR, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, INSR, MET, PRKCG, PTGS2, SIGMAR1, SLC1A1, SLC22A1, SRC, TEK, TRPV1 |
7.71899 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGES, PTGS1, PTGS2, SIGMAR1 |
4.49725 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, GRIK5, HMGCR, HSPA1A, HTR5A, KDR, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SIGMAR1, XDH |
4.3397 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, F10, FLT3, GBA2, GRIA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1 |
4.32625 |
|
[CC] GO:0031224 |
None
|
ACHE, ADORA1, ADORA3, ADRA1A, ALPL, APP, AXL, CA12, CA14, CA4, CA9, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTGES, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TEK, TRPV1, TYR |
4.09021 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, CA2, CDK6, CNR1, CNR2, DRD1, DRD2, DRD3, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PRKCG, PTGS2, SRC, TEK |
3.85437 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CNR1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, SIGMAR1, SLC22A2, SRC, TRPV1 |
3.84902 |
|
[CC] GO:0097060 |
None
|
CNR1, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, PRKCG, SIGMAR1, TRPV1 |
3.83306 |
|
[CC] GO:0042734 |
None
|
CNR1, GRIK5, GRM1, GRM3, GRM5, GRM8 |
3.79274 |
|
[CC] GO:0044464 |
cell part
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA7, CA9, CBR1, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.78113 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, CA2, CDK6, CNR1, CNR2, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, HTR6, PIK3CA, PRKCG, PTGS2, SRC, TEK |
3.77113 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, CA2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, HTR2A, HTR2B, HTR5A, PRKCG, PTGS2, SRC |
3.71852 |
|
[CC] GO:0014069 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SIGMAR1, SRC |
3.54026 |
|
[CC] GO:0099572 |
None
|
ADORA1, DRD2, GRIK5, GRM1, GRM3, GRM5, PRKCG, SIGMAR1, SRC |
3.54026 |
|
[CC] GO:0016021 |
None
|
ADORA1, ADORA3, ADRA1A, ALPL, APP, AXL, CA12, CA14, CA9, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, GRIA2, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, PTGES, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, TEK, TRPV1, TYR |
3.4006 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CBR1, CDC25B, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA2, GRIA4, GRIK5, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR4, HTR5A, INSR, KDR, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.39199 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, CA2, CNR1, CNR2, DRD2, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HTR2A, HTR2B, HTR5A, INSR, PRKCG, PTGS1, PTGS2, SIGMAR1, SLC22A2, SRC, TRPV1 |
3.33427 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.19003 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, PTGES, SRC, TNKS2, TYR |
3.07929 |
|
[CC] GO:0045121 |
membrane raft
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
3.0414 |
|
[CC] GO:0098857 |
membrane microdomain
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
3.0246 |
|
[CC] GO:0043235 |
receptor complex
|
APP, EGFR, GRIA2, GRIA4, GRIK5, GRM1, IGF1R, INSR, NR3C2, SMAD3 |
2.74691 |
|
[CC] GO:0005901 |
caveola
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.47848 |
|
[CC] GO:0098589 |
membrane region
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, PTGS2, SRC, TEK |
2.45123 |
|
[CC] GO:0043197 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.39828 |
|
[CC] GO:0044309 |
None
|
ADORA1, APP, DRD2, GRIA2, GRIA4, GRM3 |
2.37132 |
|
[CC] GO:0044463 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CNR1, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM3, HTR2A, INSR, PTGS1, SIGMAR1, SRC, TRPV1 |
2.2935 |
|
[CC] GO:0120038 |
None
|
ADORA1, AKR1B1, APP, CA4, CA9, CNR1, DRD1, DRD2, GRIA2, GRIA4, GRIK5, GRM3, HTR2A, INSR, PTGS1, SIGMAR1, SRC, TRPV1 |
2.2935 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, SLC22A1, TEK |
2.19071 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.08739 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CBR1, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GRIA4, GRIK5, GRM1, GRM5, HMGCR, HSPA1A, HTR2A, HTR4, HTR5A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A2, SLC47A1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
2.04765 |
|
[CC] GO:0044853 |
plasma membrane raft
|
ADRA1A, HTR2A, INSR, PTGS2, SRC |
2.04201 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
20.3916 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
19.7851 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CDK6, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
18.0226 |
|
[MF] GO:0030594 |
None
|
DRD1, DRD2, DRD3, GRIA2, GRIA4, GRIK5, GRM1, GRM5, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
18.0226 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
17.9024 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRA1A, AR, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, NR3C1, NR3C2, PGR, PPARA, PRKCE, RORC, SIGMAR1, SMAD3, TEK, TRPV1 |
17.8296 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
17.7596 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.3919 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.9588 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.9588 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.871 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.871 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
14.4544 |
|
[MF] GO:0008227 |
None
|
ADRA1A, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
13.5102 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRA1A, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, TEK, TRPV1 |
13.4757 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, AXL, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, SIGMAR1, TEK, TRPV1 |
13.4757 |
|
[MF] GO:0099528 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
12.488 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
12.4467 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
12.2049 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, DRD1, DRD2, DRD3, EGFR, FLT3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SIGMAR1, SRC, TEK, TOP2A, TRPV1 |
11.3191 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
9.53048 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.36122 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.32471 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
9.02896 |
|
[MF] GO:0005496 |
steroid binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC |
8.75019 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, F10, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
8.55306 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
8.12082 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRA1A, CNR1, CNR2, DRD1, DRD2, DRD3, GPR35, GRM1, GRM3, GRM5, GRM8, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, SIGMAR1 |
8.05613 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SLC1A1, SMAD3, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.62839 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6 |
7.46399 |
|
[MF] GO:0008066 |
None
|
GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8 |
7.35566 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
6.96758 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
6.96758 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
6.52666 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.30266 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
6.20286 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.19662 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, XDH |
6.12692 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.11706 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
5.9785 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HMGCR, HSD11B2, HSD17B1, NQO2, PTGES, PTGS1, PTGS2, SRC, XDH |
5.84894 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.74573 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, SRC |
5.69595 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.54324 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.42273 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.42065 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TYR |
5.25699 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, RORC, TRPV1 |
5.22368 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, HSD17B1, IGF1R, INSR, NQO2, NR3C1 |
5.19736 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
4.95067 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
4.84211 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.83726 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PRKCD, SRC, TEK |
4.67604 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
4.51164 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.17362 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.17362 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
4.0241 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
3.91866 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
3.85282 |
|
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, ADRA1A, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, GRIA2, GRIA4, GRIK5, GRM1, GRM3, GRM5, GRM8, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, PTGS1, PTGS2, PTPN1, RORC, SIGMAR1, SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.76124 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.57609 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AR, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GRM5, HMGCR, HSPA1A, MET, NR3C1, PGR, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
3.47058 |
|
[MF] GO:0043168 |
anion binding
|
ALOX15, AOX1, APP, AURKB, AXL, CDK6, CSNK2A1, EGFR, F10, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGES, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
3.46487 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SLC1A1, SRC, TEK, TOP2A, TRPV1, XDH |
3.34701 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.036 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.036 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.036 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.01503 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.9633 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
2.89495 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, XDH |
2.89371 |
|
[MF] GO:0015238 |
None
|
SLC1A1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
2.86887 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.86656 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.85174 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
2.82613 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CDK6, CSNK2A1, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
2.8154 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.79403 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.79403 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.79403 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.79403 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.79403 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.79403 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.79054 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.68946 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, GRIK5, HMGCR, IGF1R, KDR, MET, MMP9, NQO2, PGR, PTGS2, SLC22A1, SMAD3, TOP2A, TRPV1, TYR, XDH |
2.68788 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3 |
2.6872 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.6872 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.61143 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3 |
2.59118 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.58876 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.47947 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.39042 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.39042 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.39042 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.39042 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.39042 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.39042 |
|
[MF] GO:0099583 |
None
|
GRM1, GRM5 |
2.39042 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.39042 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.39042 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.27149 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.23335 |
|
[MF] GO:0004970 |
None
|
GRIA2, GRIA4, GRIK5 |
2.14403 |
|
[MF] GO:0005234 |
None
|
GRIA2, GRIA4, GRIK5 |
2.14403 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.13476 |
|
[MF] GO:0004971 |
None
|
GRIA2, GRIA4 |
2.13476 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.13476 |
|
[MF] GO:0005231 |
None
|
GRIA2, GRIA4, GRIK5, TRPV1 |
2.11243 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PRKCB, SMAD3, SRC |
2.10337 |
|
[MF] GO:1901338 |
None
|
DRD1, DRD2, DRD3 |
2.08739 |
