Prescription Description
| Prescription ID | TCMF2547 |
| Pinyin Name | Jia Wei Li Yu Tang |
| Chinese Name | 加味鲤鱼汤 |
| English Name | Added Flavor cyprinus carpio Soup |
| Function Description | |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | |
| Reference | Chinese Classical Prescriptions |
| Reference Book/link | ISBN 7-5023-3930-2 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH120 | Atractylodes macrocephala | 白术 | TCMH120 | ITSAN4430-14 |
| TCMH1065 | Cortex zingiberis | 姜皮 | TCMH1065 | |
| TCMH104 | Paeonia lactiflora | 白芍 | TCMH104 | ITSAH2416-14 |
| TCMH421 | Angelica sinensis | 当归 | TCMH421 | ITSAF173-14 |
| TCMH607 | Exodermis poria | 茯苓皮 | TCMH607 | |
| TCMH243 | Pericarpium citri reticulatae | 陈皮 | TCMH243 | |
| TCMH357 | Pericarpium arecae | 大腹皮 | TCMH357 | |
| TCMH2208 | Lindera strychnifolia | 乌药 | TCMH2208 | |
| TCMH2618 | Citrus aurantium | 枳壳 | TCMH2618 | ITSAA1279-14 |
| TCMH2046 | folium perillae | 苏叶 | TCMH2046 | |
| TCMH1721 | Panax ginseng | 人参 | TCMH1721 | GBVE1679-11 |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
| TCMH2117 | Lepidium apetalum | 葶苈子 | TCMH2117 | ITSAB3973-14 |
| TCMH1263 | Cyprinus carpio | 鲤鱼 | TCMH1263 | AMS195-08 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
Showing 1 to 10 of 130 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1172 | Staphylococcus aureus subsp. aureus RN4220 |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1189 | Pseudomonas fluorescens |
Showing 1 to 10 of 78 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC | 2.96647 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC | 2.26773 |
| [BP] GO:0001503 | ossification | ALPL, BCL2, EGFR, MMP2, MMP9, TEK | 2.98489 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, CYP1B1, EGFR, HRH3, INSR, PTGS2, SMAD3, TRPV1 | 2.83583 |
| [BP] GO:0001516 | None | MIF, PTGS1, PTGS2 | 2.73579 |
| [BP] GO:0001525 | angiogenesis | CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PTGS2, TEK | 2.11522 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK | 4.43985 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2, TBXAS1 | 6.6846 |
| [BP] GO:0001775 | cell activation | ALOX5, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, MIF, MMP9, PIK3CA, PIK3CB, SMAD3, SRC, TRPV1 | 2.31645 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, HRH4, IGF1R, INSR, KDR, MIF, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH | 3.65961 |
Showing 1 to 10 of 416 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | PIK3CA, FLT3, PIM1, PIK3CB | 3.3826 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, SMAD3, CSNK2A1, SRC, INSR, MET, EGFR, IGF1R | 7.5267 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5281 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | PIK3CA, BCL2, PIK3CB | 1.3589 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | SMAD3, PIK3CA, MMP2, BCL2, PIM1, PIK3CB, F3 | 5.5167 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2, PIK3CA, INSR, PIK3CB | 3.9578 |
| Amoebiasis_Homo sapiens_hsa05146 | PIK3CA, PIK3CB | 0.9991 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | PIK3CA, INSR, PIK3CB, IGF1R | 2.3462 |
| Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | BCL2 | 0.6271 |
| Antigen processing and presentation_Homo sapiens_hsa04612 | HSPA1A | 0.5049 |
Showing 1 to 10 of 163 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples