Prescription Description
| Prescription ID | TCMFx818 |
| Pinyin Name | Bao Ji Wan |
| Chinese Name | ä¿æµŽä¸¸ |
| English Name | Bao Ji Pills |
| Function Description | 腹痛, 腹泻, 晕动病, 感冒 |
| Indications | Abdominal pain disorder, Common cold disorder, Common cold, Diarrhea |
| Disease ICD-11 Category |
SA58 [Abdominal pain disorder (TM1), 腹痛 (TM1)
]; SA60 [Common cold disorder (TM1), 感冒 (TM1) ]; CA00 [Acute nasopharyngitis, 急性鼻咽炎 ]; ME05.1 [Diarrhoea, 腹泻 ]; |
| Human Tissues Associated with Indication | Lung, Intestine, Stomach, Blood |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH695 | Uncaria rhynchophylla | é’©è—¤ | TCMH695 | ITSAM939-14 |
| TCMH1181 | Chrysanthemum morifolium | èŠèŠ± | TCMH1181 | KX675020 |
| TCMH1024 | Tribulus terrestris | 蒺藜 | TCMH1024 | ITSAJ4258-14 |
| TCMH890 | Cortex magnoliae officinalis | 厚朴 | TCMH890 | ITSAM1591-14 |
| TCMH1533 | Saussurea lappa | 木香 | TCMH1533 | |
| TCMH211 | Atractylodes lancea | è‹æœ¯ | TCMH211 | ITSAN4439-14 |
| TCMH728 | Pogostemon cablin | 广藿香 | TCMH728 | ITSAJ4146-14 |
| TCMH677 | Pueraria lobata | è‘›æ ¹ | TCMH677 | ITSAJ4206-14 |
| TCMH925 | Exocarpium citri grandis | 化橘红 | TCMH925 | |
| TCMH118 | Angelica dahurica | 白芷 | TCMH118 | ITSAK3312-14 |
| TCMH436 | Fructus oryzae germinatus | 稻芽 | TCMH436 | |
| TCMH188 | Mentha haplocalyx | è–„è· | TCMH188 | HM595443 |
| TCMH606 | Wolfiporia cocos | 茯苓 | TCMH606 | GBPOL314-13 |
| TCMH722 | Massa medicata fermentata | 广东神曲 | TCMH722 | |
| TCMH2086 | Trichosanthes kirilowii | 天花粉 | TCMH2086 | ITSAO4359-14 |
| TCMH2486 | Coix lacryma- jobi var. ma - yuen | è–è‹¡ä» | TCMH2486 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
| TCMT140 | CA5B | Carbonic anhydrase VB | Lyase | Q9Y2D0 |
| TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT143 | CA3 | Carbonic anhydrase III | Lyase | P07451 |
| TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT190 | PTPN2 | T-cell protein-tyrosine phosphatase | Hydrolase | P17706 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT208 | MAOA | Monoamine oxidase A | Oxidoreductase | P21397 |
| TCMT212 | SRC | Tyrosine-protein kinase SRC | Kinase | P12931 |
| TCMT215 | CYP1A1 | Cytochrome P450 1A1 | Oxidoreductase | P04798 |
| TCMT217 | CYP2C8 | Cytochrome P450 2C8 | Oxidoreductase | P10632 |
| TCMT219 | CYP1A2 | Cytochrome P450 1A2 | Oxidoreductase | P05177 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT23 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | Hydrolase | P05186 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
| TCMT249 | CDK6 | Cyclin-dependent kinase 6 | Kinase | Q00534 |
| TCMT254 | CBR1 | Carbonyl reductase [NADPH] 1 | Oxidoreductase | P16152 |
| TCMT257 | CYP1B1 | Cytochrome P450 1B1 | Oxidoreductase | Q16678 |
| TCMT260 | FLT3 | Tyrosine-protein kinase receptor FLT3 | Kinase | P36888 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
| TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
| TCMT298 | FABP3 | Fatty acid binding protein muscle | Hydrolase | P05413 |
| TCMT302 | HMGCR | HMG-CoA reductase | Oxidoreductase | P04035 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT322 | MMP13 | Matrix metalloproteinase 13 | Hydrolase | P45452 |
| TCMT337 | XPO1 | Exportin-1 | Unclassified | O14980 |
| TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
| TCMT355 | CSNK1D | Casein kinase I delta | Kinase | P48730 |
| TCMT369 | IGF1R | Insulin-like growth factor I receptor | Kinase | P08069 |
| TCMT370 | KDR | Vascular endothelial growth factor receptor 2 | Kinase | P35968 |
| TCMT374 | AURKB | Serine/threonine-protein kinase Aurora-B | Kinase | Q96GD4 |
| TCMT38 | DRD2 | Dopamine D2 receptor | GPCR | P14416 |
| TCMT388 | AXL | Tyrosine-protein kinase receptor UFO | Kinase | P30530 |
| TCMT401 | MET | Hepatocyte growth factor receptor | Kinase | P08581 |
| TCMT417 | DYRK2 | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | Kinase | Q92630 |
| TCMT422 | CAMK2B | CaM kinase II beta | Kinase | Q13554 |
| TCMT44 | GLO1 | Glyoxalase I | Lyase | Q04760 |
| TCMT445 | NEK2 | Serine/threonine-protein kinase NEK2 | Kinase | P51955 |
| TCMT458 | HASPIN | Serine/threonine-protein kinase haspin | Kinase | Q8TF76 |
| TCMT462 | NEK6 | Serine/threonine-protein kinase NEK6 | Kinase | Q9HC98 |
| TCMT473 | PIM3 | Serine/threonine-protein kinase PIM3 | Kinase | Q86V86 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT484 | PLK1 | Serine/threonine-protein kinase PLK1 | Kinase | P53350 |
| TCMT558 | TOP2A | DNA topoisomerase II alpha | Isomerase | P11388 |
| TCMT563 | CDC25B | Dual specificity phosphatase Cdc25B | Hydrolase | P30305 |
| TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
| TCMT592 | XDH | Xanthine dehydrogenase | Oxidoreductase | P47989 |
| TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
| TCMT599 | UBE2N | Ubiquitin-conjugating enzyme E2 N | Transferase | P61088 |
| TCMT614 | EGLN1 | Egl nine homolog 1 | Oxidoreductase | Q9GZT9 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
| TCMT65 | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | Oxidoreductase | P14061 |
| TCMT66 | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | Oxidoreductase | P37059 |
| TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
| TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
| TCMT734 | MMP12 | Matrix metalloproteinase 12 | Hydrolase | P39900 |
| TCMT737 | APOBEC3G | DNA dC->dU-editing enzyme APOBEC-3G | Unclassified | Q9HC16 |
| TCMT740 | PIK3CG | PI3-kinase p110-gamma subunit | Transferase | P48736 |
| TCMT747 | ABCG2 | ATP-binding cassette sub-family G member 2 | Transporter | Q9UNQ0 |
| TCMT751 | DYRK1A | Dual-specificity tyrosine-phosphorylation regulated kinase 1A | Kinase | Q13627 |
| TCMT752 | CSNK2A1 | Casein kinase II alpha | Kinase | P68400 |
| TCMT763 | DYRK3 | Dual-specificity tyrosine-phosphorylation regulated kinase 3 | Kinase | O43781 |
| TCMT784 | AVPR2 | Vasopressin V2 receptor | GPCR | P30518 |
| TCMT785 | CXCR1 | Interleukin-8 receptor A | GPCR | P25024 |
| TCMT786 | CCR4 | C-C chemokine receptor type 4 | GPCR | P51679 |
| TCMT791 | PKN1 | Protein kinase N1 | Kinase | Q16512 |
| TCMT793 | PYGL | Liver glycogen phosphorylase | Transferase | P06737 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT807 | SLC22A12 | Solute carrier family 22 member 12 | Transporter | Q96S37 |
| TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
| TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
| TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
| TCMT814 | CLK1 | Dual specificty protein kinase CLK1 | Kinase | P49759 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT829 | NISCH | Nischarin | Unclassified | Q9Y2I1 |
| TCMT83 | CD38 | Lymphocyte differentiation antigen CD38 | Unclassified | P28907 |
| TCMT831 | DYRK4 | Dual specificity tyrosine-phosphorylation-regulated kinase 4 | Kinase | Q9NR20 |
| TCMT832 | DYRK1B | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Kinase | Q9Y463 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
| TCMT884 | PHF8 | Histone lysine demethylase PHF8 | Oxidoreductase | Q9UPP1 |
| TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
| TCMT965 | KDM7A | Lysine-specific demethylase 7 | Oxidoreductase | Q6ZMT4 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1172 | Staphylococcus aureus subsp. aureus RN4220 |
| TCMT1174 | Mycobacterium bovis BCG |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1177 | Haemophilus influenzae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1180 | Human herpesvirus 2 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1183 | Candida albicans SC5314 |
| TCMT1184 | Mycobacterium fortuitum |
| TCMT1185 | Mycobacterium phlei |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1187 | Enterococcus faecalis ATCC 29212 |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1191 | Bacillus megaterium |
| TCMT1192 | Bacteria |
| TCMT1193 | Staphylococcus |
| TCMT1194 | Shigella sonnei |
| TCMT1196 | Salmonella |
| TCMT1198 | Serratia marcescens |
| TCMT1199 | Streptococcus sp. 'group A' |
| TCMT1200 | Bacillus thuringiensis |
| TCMT1201 | Staphylococcus epidermidis ATCC 12228 |
| TCMT1202 | Mycoplasma hominis |
| TCMT1203 | Mycoplasma pneumoniae |
| TCMT1204 | Clostridium perfringens |
| TCMT1207 | Legionella pneumophila |
| TCMT1208 | Escherichia coli K12 |
| TCMT1209 | Staphylococcus haemolyticus |
| TCMT1210 | Streptococcus sobrinus |
| TCMT1211 | Fusobacterium nucleatum |
| TCMT1212 | Verticillium dahliae |
| TCMT1213 | Neisseria gonorrhoeae |
| TCMT1214 | Enterococcus faecium |
| TCMT1215 | Pseudomonas aeruginosa PAO1 |
| TCMT1216 | Vibrio cholerae |
| TCMT1217 | Bacillus anthracis |
| TCMT1218 | Staphylococcus aureus |
| TCMT1219 | Enterococcus |
| TCMT1220 | Streptococcus pneumoniae R6 |
| TCMT1222 | Plasmodium falciparum D6 |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1224 | Proteus mirabilis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1227 | Streptococcus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1234 | Bacillus coagulans |
| TCMT1235 | Clostridium sporogenes |
| TCMT1236 | Mycobacterium bovis |
| TCMT1237 | Mycobacterium kansasii |
| TCMT1238 | Mycobacterium xenopi |
| TCMT1239 | Mycobacterium marinum |
| TCMT1243 | Aspergillus flavus |
| TCMT1244 | Staphylococcus saprophyticus |
| TCMT1246 | Escherichia coli |
| TCMT1247 | Human herpesvirus 1 |
| TCMT1248 | Hepatitis C virus |
| TCMT1249 | Dengue virus 2 |
| TCMT1251 | Candida albicans |
| TCMT1252 | Alcaligenes faecalis |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1260 | Streptococcus agalactiae |
| TCMT1262 | Mycoplasma putrefaciens |
| TCMT1266 | Mycobacterium abscessus |
| TCMT1267 | Mycobacterium chelonae |
| TCMT1271 | Shigella flexneri |
| TCMT1272 | Campylobacter jejuni |
| TCMT1273 | Pseudomonas putida |
| TCMT1274 | Shigella boydii |
| TCMT1276 | Klebsiella |
| TCMT1277 | Serratia |
| TCMT1278 | Pseudomonas |
| TCMT1281 | Clostridium difficile |
| TCMT1284 | Penicillium expansum |
| TCMT1286 | Bacillus cereus |
| TCMT1287 | Bacillus subtilis subsp. spizizenii ATCC 6633 |
| TCMT1289 | Shigella dysenteriae |
| TCMT1290 | Acinetobacter calcoaceticus |
| TCMT1291 | Haemophilus parainfluenzae |
| TCMT1294 | Human parainfluenza virus 3 |
| TCMT1296 | Influenza A virus H3N2 |
| TCMT1299 | Morganella morganii |
| TCMT1300 | Enterobacter |
| TCMT1301 | Klebsiella sp. |
| TCMT1303 | Bacillus |
| TCMT1304 | Staphylococcus capitis |
| TCMT1305 | Salmonella enteritidis |
| TCMT1307 | Penicillium marneffei |
| TCMT1309 | Aspergillus clavatus |
| TCMT1310 | Enterococcus hirae |
| TCMT1314 | Streptococcus viridans |
| TCMT1315 | Streptococcus sp. |
| TCMT1317 | Staphylococcus lentus |
| TCMT1321 | Staphylococcus hominis |
| TCMT1322 | Streptococcus mitis |
| TCMT1326 | Shigella |
| TCMT1331 | Acinetobacter sp. |
| TCMT1332 | Bacillus licheniformis |
| TCMT1334 | Chlamydia trachomatis |
| TCMT1340 | Staphylococcus faecalis |
| TCMT1341 | Streptococcus oralis |
| TCMT1342 | Streptococcus salivarius |
| TCMT1343 | Staphylococcus simulans |
| TCMT1344 | Staphylococcus sciuri |
| TCMT1345 | Prevotella loescheii |
| TCMT1346 | Helicobacter pylori |
| TCMT1349 | Helicobacter pylori SS1 |
| TCMT1355 | Rhodococcus equi |
| TCMT1356 | Campylobacter coli |
| TCMT1358 | Bacteroides vulgatus |
| TCMT1361 | Neisseria meningitidis |
| TCMT1362 | Bordetella pertussis |
| TCMT1363 | Peptostreptococcus anaerobius |
| TCMT1366 | Prevotella bivia |
| TCMT1370 | Prevotella melaninogenica |
| TCMT1371 | Veillonella parvula |
| TCMT1375 | Clostridium tetani |
| TCMT1377 | Staphylococcus lugdunensis |
| TCMT1378 | Acinetobacter haemolyticus |
| TCMT1381 | Listeria innocua |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1383 | Streptomyces griseus |
| TCMT1388 | Prevotella disiens |
| TCMT1389 | Klebsiella oxytoca |
| TCMT1393 | Vibrio sp. |
| TCMT1394 | Mycobacterium aurum |
| TCMT1395 | Staphylococcus sp. |
| TCMT1396 | Fusobacterium |
| TCMT1399 | Chlamydophila pneumoniae |
| TCMT1400 | Mycobacterium mageritense |
| TCMT1401 | Staphylococcus warneri |
| TCMT1402 | Staphylococcus cohnii |
| TCMT1403 | Streptococcus constellatus |
| TCMT1404 | Streptococcus intermedius |
| TCMT1406 | Mycobacterium leprae |
| TCMT1407 | Aeromonas punctata |
| TCMT1408 | Colletotrichum gloeosporioides |
| TCMT1409 | Escherichia coli O157:H7 |
| TCMT1410 | Listeria monocytogenes |
| TCMT1411 | Vibrio parahaemolyticus |
| TCMT1412 | Salmonella typhimurium |
| TCMT1413 | Vibrio splendidus |
| TCMT1414 | Vibrio vulnificus |
| TCMT1415 | Vibrio fluvialis |
| TCMT1416 | Plesiomonas shigelloides |
| TCMT1417 | Aeromonas sobria |
| TCMT1418 | Enterobacteriaceae |
| TCMT1420 | Klebsiella pneumoniae subsp. ozaenae |
| TCMT1421 | Vibrio mimicus |
| TCMT1422 | Clostridium histolyticum |
| TCMT1423 | Peptostreptococcus |
| TCMT1424 | Haemophilus ducreyi |
| TCMT1425 | Moraxella bovis |
| TCMT1427 | Proteus inconstans |
| TCMT1429 | Acinetobacter pittii |
| TCMT1431 | Coxiella burnetii |
| TCMT1432 | Serratia sp. |
| TCMT1434 | Plesiomonas |
| TCMT1435 | Corynebacterium |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1442 | Leishmania donovani |
| TCMT1443 | Leishmania amazonensis |
| TCMT1444 | Fusarium oxysporum |
| TCMT1448 | Enterobacter aerogenes |
| TCMT1449 | Influenza A virus |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1457 | Leishmania major |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1460 | Mycobacterium intracellulare |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1464 | Hepatitis B virus |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples