Component ID |
TCMH73 |
Latin Name |
Tribulus terrestris |
English Name |
Tribulus fruit |
Chinese Pinyin Name |
Bai Ji Li |
中文名 |
白蒺藜 |
TCM Properties |
Warm,Bitter |
TCM Meridians |
Lung,Liver |
Therapeutic Class English |
For calming liver and containing wind |
Therapeutic Class Chinese |
平肝息风 |
Functions |
subdue hyperactivity of the liver, promote blood circulation, dispel wind, clear the eye of opacity, and arrest itching |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
ITSAJ4258-14 |
Barcode Source |
BOLDSYSTEMS |
Prescription ID | Prescription English Name | Prescription Chinese Name |
---|---|---|
TCMFx1995 | Added Flavor BXHP Decoction | 价位半夏厚朴汤 |
TCMF2510 | Added Flavor Dang Gui Drink | 加味当归饮 |
TCMF1447 | Bolus of Dendrobii for Poor Vision | 石斛夜光丸 |
TCMF2627 | Bolus of Dendrobii for Poor Vision | 石斛夜光丸 |
TCMF1452 | Boyun Tuiyi Pills | 拨云退翳丸 |
TCMF2635 | Boyun Tuiyi Pills | 拨云退翳丸 |
TCMF2826 | Dang Gui Decoction | 当归饮子 |
TCMF7428 | Dang Gui Yin Zi | 当归饮子 |
TCMF2329 | Eyesight-Improving and Upper-Heat-Removing Bolus | 明目上清丸 |
TCMFx2185 | Hyperthyroidism Reduction Bolus | |
TCMFx2371 | Mind Opening and Pain Relieving Decoction | |
TCMFx2331 | Pills for Leucorrhagia | 内补丸 |
TCMF2546 | Qi and Liver Modulating Decoction | 益气调肝降脂汤 |
TCMF2473 | Rehmannia Bolus for Improving Eyesight | 明目地黄丸 |
TCMF1392 | Rehmannia Bolus for Improving Eyesight | 明目地黄丸 |
TCMFx1241 | Sanwei Jili Powder | 三味蒺藜散 |
TCMFx1636 | Sanwei Jili Powder | 三味蒺藜散 |
TCMF2753 | Tang kuei and Tribulus Combination | 当归饮子 |
TCMF2362 | Three Ginseng and Two White Colon Disease Decoction | 三参二白汤 |
TCMF5198 | Tui Zhang Yan Ointment | 退障眼膏 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
TCMT140 | CA5B | Carbonic anhydrase VB | Lyase | Q9Y2D0 |
TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
TCMT143 | CA3 | Carbonic anhydrase III | Lyase | P07451 |
TCMT151 | PRKCA | Protein kinase C alpha | Kinase | P17252 |
TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
TCMT161 | HCAR2 | Hydroxycarboxylic acid receptor 2 | GPCR | Q8TDS4 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
TCMT186 | MAOB | Monoamine oxidase B | Oxidoreductase | P27338 |
TCMT195 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | Kinase | Q02750 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT208 | MAOA | Monoamine oxidase A | Oxidoreductase | P21397 |
TCMT226 | PDPK1 | 3-phosphoinositide dependent protein kinase-1 | Kinase | O15530 |
TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
TCMT265 | GSK3B | Glycogen synthase kinase-3 beta | Kinase | P49841 |
TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
TCMT355 | CSNK1D | Casein kinase I delta | Kinase | P48730 |
TCMT374 | AURKB | Serine/threonine-protein kinase Aurora-B | Kinase | Q96GD4 |
TCMT407 | MYLK | Myosin light chain kinase, smooth muscle | Kinase | Q15746 |
TCMT417 | DYRK2 | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | Kinase | Q92630 |
TCMT42 | KMT2A | Histone-lysine N-methyltransferase MLL | Transferase | Q03164 |
TCMT445 | NEK2 | Serine/threonine-protein kinase NEK2 | Kinase | P51955 |
TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
TCMT458 | HASPIN | Serine/threonine-protein kinase haspin | Kinase | Q8TF76 |
TCMT460 | MAPKAPK2 | MAP kinase-activated protein kinase 2 | Kinase | P49137 |
TCMT462 | NEK6 | Serine/threonine-protein kinase NEK6 | Kinase | Q9HC98 |
TCMT466 | MAPK9 | c-Jun N-terminal kinase 2 | Kinase | P45984 |
TCMT473 | PIM3 | Serine/threonine-protein kinase PIM3 | Kinase | Q86V86 |
TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
TCMT484 | PLK1 | Serine/threonine-protein kinase PLK1 | Kinase | P53350 |
TCMT507 | MAPK14 | MAP kinase p38 alpha | Kinase | Q16539 |
TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
TCMT751 | DYRK1A | Dual-specificity tyrosine-phosphorylation regulated kinase 1A | Kinase | Q13627 |
TCMT763 | DYRK3 | Dual-specificity tyrosine-phosphorylation regulated kinase 3 | Kinase | O43781 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
TCMT814 | CLK1 | Dual specificty protein kinase CLK1 | Kinase | P49759 |
TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
TCMT829 | NISCH | Nischarin | Unclassified | Q9Y2I1 |
TCMT831 | DYRK4 | Dual specificity tyrosine-phosphorylation-regulated kinase 4 | Kinase | Q9NR20 |
TCMT832 | DYRK1B | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Kinase | Q9Y463 |
TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Target ID | Target Name |
---|---|
TCMT1218 | Staphylococcus aureus |
TCMT1223 | Staphylococcus epidermidis |
TCMT1246 | Escherichia coli |
TCMT1251 | Candida albicans |
TCMT1408 | Colletotrichum gloeosporioides |
TCMT1438 | Plasmodium falciparum |
TCMT1442 | Leishmania donovani |
TCMT1444 | Fusarium oxysporum |
TCMT1454 | Bacillus subtilis |
TCMT1463 | Mycobacterium tuberculosis |
Ingredient ID: TCMC2524
Formula: C34H28Br4N4O8
Ingredient ID: TCMC2512
Formula: C12H8S3
Ingredient ID: TCMC2500
Formula: C24H28N2O6
Ingredient ID: TCMC1767
Formula: C18H19NO4
Ingredient ID: TCMC1310
Formula: C12H10N2O
Ingredient ID: TCMC1309
Formula: C13H12N2O
Ingredient ID: TCMC1308
Formula: C12H10N2
Ingredient ID: TCMC1173
Formula: C10H10O4
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC1173 | C10H10O4 | Ferulic Acid | 194.06 | -0.3908 | 2.12 | 1.231 | 2 | 2 | 66.76 | 6 | 1 | 14 | 0 |
TCMC1308 | C12H10N2 | Harman | 182.08 | 0.0191 | 2.56 | 2.968 | 2 | 1 | 28.68 | 1 | 3 | 14 | 0 |
TCMC1309 | C13H12N2O | Harmine | 212.09 | -0.0327 | 2.56 | 2.313 | 2 | 1 | 37.91 | 3 | 3 | 16 | 0 |
TCMC1310 | C12H10N2O | Harmol | 198.08 | -0.8687 | 2.45 | 2.112 | 3 | 2 | 44.89 | 1 | 3 | 15 | 0 |
TCMC1767 | C18H19NO4 | N-Trans-Feruloyl Tyramine | 313.13 | -0.6499 | 2.89 | 3.109 | 2 | 3 | 82.28 | 10 | 2 | 23 | 0 |
TCMC2500 | C24H28N2O6 | Terrestribisamide | 440.19 | -1.4664 | 3.22 | 3.384 | 4 | 4 | 124.1 | 17 | 2 | 32 | 1 |
TCMC2512 | C12H8S3 | Alpha-Terthienyl | 247.98 | 1.7718 | 2.45 | 4.693 | 0 | 0 | 84.72 | 2 | 3 | 15 | 0 |
TCMC2524 | C34H28Br4N4O8 | Bastadin 13 | 935.86 | 1.875 | 3.44 | 8.378 | 4 | 6 | 189.28 | 10 | 4 | 50 | 2 |